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Lista de obras de Benedetta Mannini

Bis(indolyl)phenylmethane derivatives are effective small molecules for inhibition of amyloid fibril formation by hen lysozyme.

artículo científico publicado en 2016

Chaperones as Suppressors of Protein Misfolded Oligomer Toxicity

artículo científico publicado en 2017

Differential Interactome and Innate Immune Response Activation of Two Structurally Distinct Misfolded Protein Oligomers

scientific article published on 02 August 2019

Multistep Inhibition of α-Synuclein Aggregation and Toxicity in Vitro and in Vivo by Trodusquemine

article

Proteome-wide observation of the phenomenon of life on the edge of solubility

artículo científico publicado en 2019

Rational design of a conformation-specific antibody for the quantification of Aβ oligomers

artículo científico publicado en 2020

Rationally Designed Antibodies as Research Tools to Study the Structure-Toxicity Relationship of Amyloid-β Oligomers

artículo científico publicado en 2020

Single molecule secondary structure determination of proteins through infrared absorption nanospectroscopy

artículo científico publicado en 2020

Small-molecule sequestration of amyloid-β as a drug discovery strategy for Alzheimer's disease

artículo científico publicado en 2020

Stabilization and Characterization of Cytotoxic Aβ40 Oligomers Isolated from an Aggregation Reaction in the Presence of Zinc Ions

artículo científico publicado en 2018

Surface-Catalyzed Secondary Nucleation Dominates the Generation of Toxic IAPP Aggregates

artículo científico publicado en 2021

Systematic development of small molecules to inhibit specific microscopic steps of Aβ42 aggregation in Alzheimer's disease

artículo científico publicado en 2017

Toxic HypF-N Oligomers Selectively Bind the Plasma Membrane to Impair Cell Adhesion Capability.

artículo científico publicado en 2018

Toxicity of protein oligomers is rationalized by a function combining size and surface hydrophobicity

artículo científico publicado en 2014

Transthyretin suppresses the toxicity of oligomers formed by misfolded proteins in vitro

artículo científico publicado en 2013

Trodusquemine displaces protein misfolded oligomers from cell membranes and abrogates their cytotoxicity through a generic mechanism

scientific article published on 13 August 2020

Trodusquemine enhances Aβ aggregation but suppresses its toxicity by displacing oligomers from cell membranes

scientific article published in Nature Communications

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