Lista de obras - Avril A.B. Robertson - Dominio Público Uruguay

A multicomponent toxin from Bacillus cereus incites inflammation and shapes host outcome via the NLRP3 inflammasome

artículo científico publicado en 2018

A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases.

artículo científico publicado en 2015

An optimized whole blood assay measuring expression and activity of NLRP3, NLRC4 and AIM2 inflammasomes

artículo científico publicado en 2017

An optimized whole blood assay measuring expression and activity of NLRP3-, NLRC4 and AIM2-inflammasomes.

artículo científico publicado en 2015

Antimicrobial octapeptin C4 analogues active against Cryptococcus species.

artículo científico publicado en 2017

Bacillus cereus non-haemolytic enterotoxin activates the NLRP3 inflammasome ⬇️

artículo científico publicado en 2020

Caspase-1-dependent inflammasomes mediate photoreceptor cell death in photo-oxidative damage-induced retinal degeneration

artículo científico publicado en 2020

Characterisation of small molecule ligands 4CMTB and 2CTAP as modulators of human FFA2 receptor signalling

artículo científico publicado en 2018

Clonal hematopoiesis associated with TET2 deficiency accelerates atherosclerosis development in mice

artículo científico publicado en 2017

Cryptococcus neoformans ADS lyase is an enzyme essential for virulence whose crystal structure reveals features exploitable in antifungal drug design.

artículo científico publicado en 2017

Efficient synthesis of anacardic acid analogues and their antibacterial activities.

artículo científico publicado en 2013

Fishing for Drug Targets: A Focus on Diazirine Photoaffinity Probe Synthesis.

artículo científico publicado en 2018

GMP Synthase Is Required for Virulence Factor Production and Infection by Cryptococcus neoformans.

artículo científico publicado en 2017

High-performance liquid chromatographic separation of natural and synthetic desulphoglucosinolates and their chemical validation by UV, NMR and chemical ionisation-MS methods

scientific article published on 01 July 2001

Human Monocytes Engage an Alternative Inflammasome Pathway

artículo científico publicado en 2016

Identification, Synthesis, and Biological Evaluation of the Major Human Metabolite of NLRP3 Inflammasome Inhibitor MCC950.

artículo científico publicado en 2016

Inflammasome activity is essential for one kidney/deoxycorticosterone acetate/salt-induced hypertension in mice.

artículo científico publicado en 2015

Inflammasome inhibition prevents α-synuclein pathology and dopaminergic neurodegeneration in mice

artículo científico publicado en 2018

Inflammasome-Independent Role for NLRP3 in Controlling Innate Antihelminth Immunity and Tissue Repair in the Lung

scientific article published on 04 October 2019

Inflammasomes in the lung.

artículo científico publicado en 2017

Inhibiting the NLRP3 inflammasome with MCC950 promotes non-phlogistic clearance of amyloid-β and cognitive function in APP/PS1 mice.

artículo científico publicado en 2016

MCC950 directly targets the NLRP3 ATP-hydrolysis motif for inflammasome inhibition

scientific article published on 13 May 2019

Metabolic competition between host and pathogen dictates inflammasome responses to fungal infection

artículo científico publicado en 2020

Myeloid-derived miR-223 regulates intestinal inflammation via repression of the NLRP3 inflammasome.

artículo científico publicado en 2017

NLRP3 inflammasome activation downstream of cytoplasmic LPS recognition by both caspase-4 and caspase-5.

artículo científico publicado en 2015

NLRP3 inflammasome blockade reduces liver inflammation and fibrosis in experimental NASH in mice.

artículo científico publicado en 2017

Natural product and natural product derived drugs in clinical trials.

artículo científico publicado en 2014

PB1-F2 Peptide Derived from Avian Influenza A Virus H7N9 Induces Inflammation via Activation of the NLRP3 Inflammasome.

artículo científico publicado en 2016

Pharmacological targeting of the transcription factor SOX18 delays breast cancer in mice.

artículo científico publicado en 2017

Pressor response to angiotensin II is enhanced in aged mice and associated with inflammation, vasoconstriction and oxidative stress

artículo científico publicado en 2017

Prevention of the foreign body response to implantable medical devices by inflammasome inhibition

artículo científico publicado en 2022

Reassessing the role of the NLRP3 inflammasome during pathogenic influenza A virus infection via temporal inhibition

artículo científico publicado en 2016

Small-Molecule Inhibitors of the SOX18 Transcription Factor.

artículo científico publicado en 2017

Specific inhibition of NLRP3 in chikungunya disease reveals a role for inflammasomes in alphavirus-induced inflammation.

artículo científico publicado en 2017

Strain- and host species-specific inflammasome activation, IL-1β release, and cell death in macrophages infected with uropathogenic Escherichia coli

artículo científico publicado en 2015

Sulfonylureas as Concomitant Insulin Secretagogues and NLRP3 Inflammasome Inhibitors.

artículo científico publicado en 2017

Synthesis of deuterium-labelled analogues of NLRP3 inflammasome inhibitor MCC950.

artículo científico publicado en 2017

T helper 1 immunity requires complement-driven NLRP3 inflammasome activity in CD4⁺ T cells.

artículo científico publicado en 2016

The Bohlmann–Rahtz route to functionalised pyridine scaffolds and their use in library synthesis

article published in 2003

The Endoplasmic Reticulum-Mitochondrion Tether ERMES Orchestrates Fungal Immune Evasion, Illuminating Inflammasome Responses to Hyphal Signals

artículo científico publicado en 2016

The NLRP3 inflammasome functions as a driver of the myelodysplastic syndrome phenotype ⬇️

artículo científico publicado en 2016

Lista de obras de Avril A.B. Robertson

A multicomponent toxin from Bacillus cereus incites inflammation and shapes host outcome via the NLRP3 inflammasome

A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases.

An optimized whole blood assay measuring expression and activity of NLRP3, NLRC4 and AIM2 inflammasomes

An optimized whole blood assay measuring expression and activity of NLRP3-, NLRC4 and AIM2-inflammasomes.

Antimicrobial octapeptin C4 analogues active against Cryptococcus species.

Bacillus cereus non-haemolytic enterotoxin activates the NLRP3 inflammasome ⬇️

Caspase-1-dependent inflammasomes mediate photoreceptor cell death in photo-oxidative damage-induced retinal degeneration

Characterisation of small molecule ligands 4CMTB and 2CTAP as modulators of human FFA2 receptor signalling

Clonal hematopoiesis associated with TET2 deficiency accelerates atherosclerosis development in mice

Cryptococcus neoformans ADS lyase is an enzyme essential for virulence whose crystal structure reveals features exploitable in antifungal drug design.

Efficient synthesis of anacardic acid analogues and their antibacterial activities.

Fishing for Drug Targets: A Focus on Diazirine Photoaffinity Probe Synthesis.

GMP Synthase Is Required for Virulence Factor Production and Infection by Cryptococcus neoformans.

High-performance liquid chromatographic separation of natural and synthetic desulphoglucosinolates and their chemical validation by UV, NMR and chemical ionisation-MS methods

Human Monocytes Engage an Alternative Inflammasome Pathway

Identification, Synthesis, and Biological Evaluation of the Major Human Metabolite of NLRP3 Inflammasome Inhibitor MCC950.

Inflammasome activity is essential for one kidney/deoxycorticosterone acetate/salt-induced hypertension in mice.

Inflammasome inhibition prevents α-synuclein pathology and dopaminergic neurodegeneration in mice

Inflammasome-Independent Role for NLRP3 in Controlling Innate Antihelminth Immunity and Tissue Repair in the Lung

Inflammasomes in the lung.

Inhibiting the NLRP3 inflammasome with MCC950 promotes non-phlogistic clearance of amyloid-β and cognitive function in APP/PS1 mice.

MCC950 directly targets the NLRP3 ATP-hydrolysis motif for inflammasome inhibition

Metabolic competition between host and pathogen dictates inflammasome responses to fungal infection

Myeloid-derived miR-223 regulates intestinal inflammation via repression of the NLRP3 inflammasome.

NLRP3 inflammasome activation downstream of cytoplasmic LPS recognition by both caspase-4 and caspase-5.

NLRP3 inflammasome blockade reduces liver inflammation and fibrosis in experimental NASH in mice.

Natural product and natural product derived drugs in clinical trials.

PB1-F2 Peptide Derived from Avian Influenza A Virus H7N9 Induces Inflammation via Activation of the NLRP3 Inflammasome.

Pharmacological targeting of the transcription factor SOX18 delays breast cancer in mice.

Pressor response to angiotensin II is enhanced in aged mice and associated with inflammation, vasoconstriction and oxidative stress

Prevention of the foreign body response to implantable medical devices by inflammasome inhibition

Reassessing the role of the NLRP3 inflammasome during pathogenic influenza A virus infection via temporal inhibition

Small-Molecule Inhibitors of the SOX18 Transcription Factor.

Specific inhibition of NLRP3 in chikungunya disease reveals a role for inflammasomes in alphavirus-induced inflammation.

Strain- and host species-specific inflammasome activation, IL-1β release, and cell death in macrophages infected with uropathogenic Escherichia coli

Sulfonylureas as Concomitant Insulin Secretagogues and NLRP3 Inflammasome Inhibitors.

Synthesis of deuterium-labelled analogues of NLRP3 inflammasome inhibitor MCC950.

T helper 1 immunity requires complement-driven NLRP3 inflammasome activity in CD4⁺ T cells.

The Bohlmann–Rahtz route to functionalised pyridine scaffolds and their use in library synthesis

The Endoplasmic Reticulum-Mitochondrion Tether ERMES Orchestrates Fungal Immune Evasion, Illuminating Inflammasome Responses to Hyphal Signals

The NLRP3 inflammasome functions as a driver of the myelodysplastic syndrome phenotype ⬇️