Lista de obras - Poul Henning Jensen - Dominio Público Uruguay

A Longitudinal Study of Total and Phosphorylated α-Synuclein with Other Biomarkers in Cerebrospinal Fluid of Alzheimer's Disease and Mild Cognitive Impairment

artículo científico publicado en 2018

A progressive dopaminergic phenotype associated with neurotoxic conversion of α-synuclein in BAC-transgenic rats

artículo científico publicado en 2013

Accumulation of toxic α-synuclein oligomer within endoplasmic reticulum occurs in α-synucleinopathy in vivo.

artículo científico publicado en 2012

Alpha-synuclein aggregates activate calcium pump SERCA leading to calcium dysregulation.

artículo científico publicado en 2018

Alpha-synuclein aggregation and Ser-129 phosphorylation-dependent cell death in oligodendroglial cells.

artículo científico publicado en 2009

Alpha-synuclein and presynaptic function: implications for Parkinson's disease.

artículo científico publicado en 2002

Alpha-synuclein redistributes to neuromelanin lipid in the substantia nigra early in Parkinson's disease.

artículo científico publicado en 2005

Association of alpha-synuclein and mutants with lipid membranes: spin-label ESR and polarized IR

scientific article published on 01 March 2006

Astrocytic but not neuronal increased expression and redistribution of parkin during unfolded protein stress

scientific journal article

Binding of alpha-synuclein to brain vesicles is abolished by familial Parkinson's disease mutation.

artículo científico publicado en 1998

CD4 T cells react to local increase of α-synuclein in a pathology-associated variant-dependent manner and modify brain microglia in absence of brain pathology.

artículo científico publicado en 2018

Ca2+ binding to alpha-synuclein regulates ligand binding and oligomerization

artículo científico publicado en 2001

Caspase I-related protease inhibition retards the execution of okadaic acid- and camptothecin-induced apoptosis and PAI-2 cleavage, but not commitment to cell death in HL-60 cells.

artículo científico publicado en 1999

Caspase-1 and caspase-8 cleave and inactivate cellular parkin

scientific article published on 11 April 2003

Caspase-mediated parkin cleavage in apoptotic cell death.

artículo científico publicado en 2002

Cell association and degradation of pregnancy zone protein-chymotrypsin complex in cultured human monocytes.

artículo científico publicado en 1988

Cerebrospinal fluid α-synuclein contributes to the differential diagnosis of Alzheimer's disease.

artículo científico publicado en 2018

Characterization of carbohydrates in the alpha 2-macroglobulin receptor

scientific article published on 01 June 1992

Characterizing the dynamics of α-synuclein oligomers using hydrogen/deuterium exchange monitored by mass spectrometry

artículo científico publicado en 2013

Cleaved intracellular plasminogen activator inhibitor 2 in human myeloleukaemia cells is a marker of apoptosis.

artículo científico publicado en 1994

Co-expression of C-terminal truncated alpha-synuclein enhances full-length alpha-synuclein-induced pathology.

artículo científico publicado en 2010

DJ-1 interactions with α-synuclein attenuate aggregation and cellular toxicity in models of Parkinson's disease

artículo científico publicado en 2014

Detection of elevated levels of soluble alpha-synuclein oligomers in post-mortem brain extracts from patients with dementia with Lewy bodies.

artículo científico publicado en 2009

Down-regulation of parkin protein in transient focal cerebral ischemia: A link between stroke and degenerative disease?

scientific journal article

ELISA method to detect α-synuclein oligomers in cell and animal models.

artículo científico publicado en 2018

Evidence for binding of human pregnancy zone protein-proteinase complex to α2-macroglobulin receptors

artículo científico publicado en 1986

Expression of tissue transglutaminase in human bladder carcinoma

scientific article published on 01 December 1997

How epigallocatechin gallate can inhibit α-synuclein oligomer toxicity in vitro

artículo científico publicado en 2014

Human hepatocytes exhibit receptors for alpha 2-macroglobulin and pregnancy zone protein-proteinase complexes

artículo científico publicado en 1988

Identification of synaptosomal proteins binding to monomeric and oligomeric α-synuclein.

artículo científico publicado en 2015

In situ and in vitro study of colocalization and segregation of alpha-synuclein, ubiquitin, and lipids in Lewy bodies

scientific article published on 01 December 2000

Incipient intranuclear inclusion body disease in a 78-year-old woman.

artículo científico publicado en 2011

Inflammation kinase PKR phosphorylates α-synuclein and causes α-synuclein-dependent cell death.

artículo científico publicado en 2018

Investigation of RNA Synthesis Using 5-Bromouridine Labelling and Immunoprecipitation

artículo científico publicado en 2018

Is alpha-synuclein the culprit of the Parkinsonian neurodegeneration?

scientific article published on 01 January 2008

Localization of a single transglutaminase-reactive glutamine in the third domain of RAP, the alpha2-macroglobulin receptor-associated protein

artículo científico publicado en 1999

Localization of transglutaminase-reactive glutamine residues in bovine osteopontin.

artículo científico publicado en 1994

Long-Term Exposure to PFE-360 in the AAV-α-Synuclein Rat Model: Findings and Implications

artículo científico publicado en 2019

Mannose 6-Phosphate Receptor Is Reduced in -Synuclein Overexpressing Models of Parkinsons Disease

artículo científico publicado en 2016

Multiple Roles of Heparin in the Aggregation of p25α

Natively unfolded tubulin polymerization promoting protein TPPP/p25 is a common marker of alpha-synucleinopathies

artículo científico publicado en 2004

Oligodendrocytes within astrocytes ("emperipolesis") in the cerebral white matter in hepatic and hypoglycemic encephalopathy.

artículo científico publicado en 2006

Organotypic slice culture model demonstrates inter-neuronal spreading of alpha-synuclein aggregates

scientific article published on 19 December 2019

P25α / TPPP expression increases plasma membrane presentation of the dopamine transporter and enhances cellular sensitivity to dopamine toxicity

artículo científico publicado en 2010

PFE-360-induced LRRK2 inhibition induces reversible, non-adverse renal changes in rats

artículo científico publicado en 2018

Parkin is recruited into aggresomes in a stress-specific manner: over-expression of parkin reduces aggresome formation but can be dissociated from parkin's effect on neuronal survival

artículo científico publicado en 2004

Parkinson's disease-like burst firing activity in subthalamic nucleus induced by AAV-α-synuclein is normalized by LRRK2 modulation.

artículo científico publicado en 2018

Pathogenic effects of alpha-synuclein aggregation.

artículo científico publicado en 2005

Peroxiredoxin 6 in human brain: molecular forms, cellular distribution and association with Alzheimer's disease pathology

artículo científico publicado en 2008

Phosphorylated α-synuclein in Parkinson's disease: correlation depends on disease severity

artículo científico publicado en 2015

Plasma α-synuclein and cognitive impairment in the Parkinson's Associated Risk Syndrome: A pilot study

scientific article published on 27 April 2018

Pregnancy zone protein: a re-evaluation of serum levels in healthy women and in women suffering from breast cancer or trophoblastic disease ⬇️

artículo científico publicado el 1 de septiembre de 1990

Proteasomal inhibition by alpha-synuclein filaments and oligomers.

artículo científico publicado en 2004

Protein Partners of α-Synuclein in Health and Disease

artículo científico publicado en 2016

Purification of the human placental α2 -macroglobulin receptor

artículo científico publicado en 1989

Receptors for alpha 2-macroglobulin- and pregnancy zone protein-proteinase complexes in the human placental syncytiotrophoblast.

artículo científico publicado en 1988

Reduced Cytosolic Calcium as an Early Decisive Cellular State in Parkinson's Disease and Synucleinopathies

artículo científico publicado en 2018

Residues in the synuclein consensus motif of the α-synuclein fragment, NAC, participate in transglutaminase-catalysed cross-linking to Alzheimer-disease amyloid βA4 peptide ⬇️

artículo científico publicado el 15 de agosto de 1995

Ser129D mutant alpha-synuclein induces earlier motor dysfunction while S129A results in distinctive pathology in a rat model of Parkinson's disease.

artículo científico publicado en 2013

Structural and functional characterization of two alpha-synuclein strains

artículo científico publicado en 2013

The C-D interhelical domain of the serpin plasminogen activator inhibitor-type 2 is required for protection from TNF-alpha induced apoptosis

scientific article published on 01 February 1998

The glycan structure of albumin Redhill, a glycosylated variant of human serum albumin.

artículo científico publicado en 2001

Trans-synaptic spreading of alpha-synuclein pathology through sensory afferents leads to sensory nerve degeneration and neuropathic pain

artículo científico publicado en 2021

Tubulin polymerization-promoting protein (TPPP/p25α) promotes unconventional secretion of α-synuclein through exophagy by impairing autophagosome-lysosome fusion

artículo científico publicado en 2013

Type-1 inhibitor of plasminogen activators. Distinction between latent, activated and reactive centre-cleaved forms with thermal stability and monoclonal antibodies

artículo científico publicado en 1991

Type-2 plasminogen-activator inhibitor is a substrate for trophoblast transglutaminase and factor XIIIa. Transglutaminase-catalyzed cross-linking to cellular and extracellular structures

artículo científico publicado en 1993

Urokinase binds to a plasminogen activator inhibitor type-2-like molecule in placental microvillous membranes

artículo científico publicado en 1989

alpha-Synuclein fibrils constitute the central core of oligodendroglial inclusion filaments in multiple system atrophy.

artículo científico publicado en 2003

p25alpha Stimulates alpha-synuclein aggregation and is co-localized with aggregated alpha-synuclein in alpha-synucleinopathies

artículo científico publicado en 2005

p25alpha is flexible but natively folded and binds tubulin with oligomeric stoichiometry

artículo científico publicado en 2005

p25alpha relocalizes in oligodendroglia from myelin to cytoplasmic inclusions in multiple system atrophy

artículo científico publicado en 2007

α-Synuclein Association with Phosphatidylglycerol Probed by Lipid Spin Labels ⬇️

artículo científico publicado el 11 de noviembre de 2003

Lista de obras de Poul Henning Jensen

A Longitudinal Study of Total and Phosphorylated α-Synuclein with Other Biomarkers in Cerebrospinal Fluid of Alzheimer's Disease and Mild Cognitive Impairment

A progressive dopaminergic phenotype associated with neurotoxic conversion of α-synuclein in BAC-transgenic rats

Accumulation of toxic α-synuclein oligomer within endoplasmic reticulum occurs in α-synucleinopathy in vivo.

Alpha-synuclein aggregates activate calcium pump SERCA leading to calcium dysregulation.

Alpha-synuclein aggregation and Ser-129 phosphorylation-dependent cell death in oligodendroglial cells.

Alpha-synuclein and presynaptic function: implications for Parkinson's disease.

Alpha-synuclein redistributes to neuromelanin lipid in the substantia nigra early in Parkinson's disease.

Association of alpha-synuclein and mutants with lipid membranes: spin-label ESR and polarized IR

Astrocytic but not neuronal increased expression and redistribution of parkin during unfolded protein stress

Binding of alpha-synuclein to brain vesicles is abolished by familial Parkinson's disease mutation.

CD4 T cells react to local increase of α-synuclein in a pathology-associated variant-dependent manner and modify brain microglia in absence of brain pathology.

Ca2+ binding to alpha-synuclein regulates ligand binding and oligomerization

Caspase I-related protease inhibition retards the execution of okadaic acid- and camptothecin-induced apoptosis and PAI-2 cleavage, but not commitment to cell death in HL-60 cells.

Caspase-1 and caspase-8 cleave and inactivate cellular parkin

Caspase-mediated parkin cleavage in apoptotic cell death.

Cell association and degradation of pregnancy zone protein-chymotrypsin complex in cultured human monocytes.

Cerebrospinal fluid α-synuclein contributes to the differential diagnosis of Alzheimer's disease.

Characterization of carbohydrates in the alpha 2-macroglobulin receptor

Characterizing the dynamics of α-synuclein oligomers using hydrogen/deuterium exchange monitored by mass spectrometry

Cleaved intracellular plasminogen activator inhibitor 2 in human myeloleukaemia cells is a marker of apoptosis.

Co-expression of C-terminal truncated alpha-synuclein enhances full-length alpha-synuclein-induced pathology.

DJ-1 interactions with α-synuclein attenuate aggregation and cellular toxicity in models of Parkinson's disease

Detection of elevated levels of soluble alpha-synuclein oligomers in post-mortem brain extracts from patients with dementia with Lewy bodies.

Down-regulation of parkin protein in transient focal cerebral ischemia: A link between stroke and degenerative disease?

ELISA method to detect α-synuclein oligomers in cell and animal models.

Evidence for binding of human pregnancy zone protein-proteinase complex to α2-macroglobulin receptors

Expression of tissue transglutaminase in human bladder carcinoma

How epigallocatechin gallate can inhibit α-synuclein oligomer toxicity in vitro

Human hepatocytes exhibit receptors for alpha 2-macroglobulin and pregnancy zone protein-proteinase complexes

Identification of synaptosomal proteins binding to monomeric and oligomeric α-synuclein.

In situ and in vitro study of colocalization and segregation of alpha-synuclein, ubiquitin, and lipids in Lewy bodies

Incipient intranuclear inclusion body disease in a 78-year-old woman.

Inflammation kinase PKR phosphorylates α-synuclein and causes α-synuclein-dependent cell death.

Investigation of RNA Synthesis Using 5-Bromouridine Labelling and Immunoprecipitation

Is alpha-synuclein the culprit of the Parkinsonian neurodegeneration?

Localization of a single transglutaminase-reactive glutamine in the third domain of RAP, the alpha2-macroglobulin receptor-associated protein

Localization of transglutaminase-reactive glutamine residues in bovine osteopontin.

Long-Term Exposure to PFE-360 in the AAV-α-Synuclein Rat Model: Findings and Implications

Mannose 6-Phosphate Receptor Is Reduced in -Synuclein Overexpressing Models of Parkinsons Disease

Multiple Roles of Heparin in the Aggregation of p25α

Natively unfolded tubulin polymerization promoting protein TPPP/p25 is a common marker of alpha-synucleinopathies

Oligodendrocytes within astrocytes ("emperipolesis") in the cerebral white matter in hepatic and hypoglycemic encephalopathy.

Organotypic slice culture model demonstrates inter-neuronal spreading of alpha-synuclein aggregates

P25α / TPPP expression increases plasma membrane presentation of the dopamine transporter and enhances cellular sensitivity to dopamine toxicity

PFE-360-induced LRRK2 inhibition induces reversible, non-adverse renal changes in rats

Parkin is recruited into aggresomes in a stress-specific manner: over-expression of parkin reduces aggresome formation but can be dissociated from parkin's effect on neuronal survival

Parkinson's disease-like burst firing activity in subthalamic nucleus induced by AAV-α-synuclein is normalized by LRRK2 modulation.

Pathogenic effects of alpha-synuclein aggregation.

Peroxiredoxin 6 in human brain: molecular forms, cellular distribution and association with Alzheimer's disease pathology

Phosphorylated α-synuclein in Parkinson's disease: correlation depends on disease severity

Plasma α-synuclein and cognitive impairment in the Parkinson's Associated Risk Syndrome: A pilot study

Pregnancy zone protein: a re-evaluation of serum levels in healthy women and in women suffering from breast cancer or trophoblastic disease ⬇️

Proteasomal inhibition by alpha-synuclein filaments and oligomers.

Protein Partners of α-Synuclein in Health and Disease

Purification of the human placental α2 -macroglobulin receptor

Receptors for alpha 2-macroglobulin- and pregnancy zone protein-proteinase complexes in the human placental syncytiotrophoblast.

Reduced Cytosolic Calcium as an Early Decisive Cellular State in Parkinson's Disease and Synucleinopathies

Residues in the synuclein consensus motif of the α-synuclein fragment, NAC, participate in transglutaminase-catalysed cross-linking to Alzheimer-disease amyloid βA4 peptide ⬇️

Ser129D mutant alpha-synuclein induces earlier motor dysfunction while S129A results in distinctive pathology in a rat model of Parkinson's disease.

Structural and functional characterization of two alpha-synuclein strains

The C-D interhelical domain of the serpin plasminogen activator inhibitor-type 2 is required for protection from TNF-alpha induced apoptosis

The glycan structure of albumin Redhill, a glycosylated variant of human serum albumin.

Trans-synaptic spreading of alpha-synuclein pathology through sensory afferents leads to sensory nerve degeneration and neuropathic pain

Tubulin polymerization-promoting protein (TPPP/p25α) promotes unconventional secretion of α-synuclein through exophagy by impairing autophagosome-lysosome fusion

Type-1 inhibitor of plasminogen activators. Distinction between latent, activated and reactive centre-cleaved forms with thermal stability and monoclonal antibodies

Type-2 plasminogen-activator inhibitor is a substrate for trophoblast transglutaminase and factor XIIIa. Transglutaminase-catalyzed cross-linking to cellular and extracellular structures

Urokinase binds to a plasminogen activator inhibitor type-2-like molecule in placental microvillous membranes

alpha-Synuclein fibrils constitute the central core of oligodendroglial inclusion filaments in multiple system atrophy.

p25alpha Stimulates alpha-synuclein aggregation and is co-localized with aggregated alpha-synuclein in alpha-synucleinopathies

p25alpha is flexible but natively folded and binds tubulin with oligomeric stoichiometry

p25alpha relocalizes in oligodendroglia from myelin to cytoplasmic inclusions in multiple system atrophy

α-Synuclein Association with Phosphatidylglycerol Probed by Lipid Spin Labels ⬇️