Lista de obras - Stephen G Ward - Dominio Público Uruguay

Activation of phosphatidylinositol 3-kinase by interleukin-13. An inhibitory signal for inducible nitric-oxide synthase expression in epithelial cell line HT-29.

artículo científico publicado en 1997

Activation of the PI3K effector protein kinase B following ligation of CD28 or Fas

artículo científico publicado en 1997

Analysis of CXCR3 and atypical variant expression and signalling in human T lymphocytes.

artículo científico publicado en 2010

Antagonism of the platelet activating factor-induced rise of the intracellular calcium ion concentration of U937 cells ⬇️

artículo científico publicado el 1 de abril de 1988

Antibody ligation of CD7 leads to association with phosphoinositide 3-kinase and phosphatidylinositol 3,4,5-trisphosphate formation in T lymphocytes

artículo científico publicado en 1995

Both CD28 ligands CD80 (B7-1) and CD86 (B7-2) activate phosphatidylinositol 3-kinase, and wortmannin reveals heterogeneity in the regulation of T cell IL-2 secretion.

artículo científico publicado en 1995

CD28 stimulates tyrosine phosphorylation, cellular redistribution and catalytic activity of the inositol lipid 5-phosphatase SHIP

scientific article published on 01 November 1999

CD28: a signalling perspective.

artículo científico publicado en 1996

Chemokines and T lymphocytes: more than an attraction

artículo científico publicado en 1998

Chemokines: understanding their role in T-lymphocyte biology.

artículo científico publicado en 1998

Comparison of infrared thermography and laser speckle contrast imaging for the dynamic assessment of digital microvascular function.

artículo científico publicado en 2011

Des-gamma-carboxy prothrombin stimulates human vascular endothelial cell growth and migration.

artículo científico publicado en 2009

Development and characterisation of tetracycline-regulated phosphoinositide 3-kinase mutants: assessing the role of multiple phosphoinositide 3-kinases in chemokine signaling.

artículo científico publicado en 2003

Differential modulation of COX-2 expression in A549 airway epithelial cells by structurally distinct PPAR(gamma) agonists: evidence for disparate functional effects which are independent of NF-(kappa)B and PPAR(gamma).

artículo científico publicado en 2005

Differential regulation of prostaglandin E biosynthesis by interferon-gamma in colonic epithelial cells

artículo científico publicado en 2004

Evidence that SHIP-1 contributes to phosphatidylinositol 3,4,5-trisphosphate metabolism in T lymphocytes and can regulate novel phosphoinositide 3-kinase effectors

artículo científico publicado en 2002

Evidence that a kinase distinct from protein kinase C and phosphatidylinositol 3-kinase mediates ligation-dependent serine/threonine phosphorylation of the T-lymphocyte co-stimulatory molecule CD28.

artículo científico publicado en 1997

Evidence that phospholipase-C-dependent, calcium-independent mechanisms are required for directional migration of T-lymphocytes in response to the CCR4 ligands CCL17 and CCL22.

artículo científico publicado en 2006

Evidence that the lipid phosphatase SHIP-1 regulates T lymphocyte morphology and motility

artículo científico publicado en 2011

Expression and agonist responsiveness of CXCR3 variants in human T lymphocytes.

artículo científico publicado en 2011

Fine tuning T lymphocytes: a role for the lipid phosphatase SHIP-1.

artículo científico publicado en 2009

Genetic ablation of PI3Kγ results in defective IL-17RA signalling in T lymphocytes and increased IL-17 levels

artículo científico publicado en 2012

Heterologous regulation of chemokine receptor signaling by the lipid phosphatase SHIP in lymphocytes.

artículo científico publicado en 2005

High PD-1/PD-L1 checkpoint interaction infers tumor selection and therapeutic sensitivity to anti-PD-1/PD-L1 treatment

scientific article published on 27 August 2020

Hnf4α is a key gene that can generate columnar metaplasia in oesophageal epithelium.

artículo científico publicado en 2016

How does inflammation cause Barrett's metaplasia?

scientific article published on 12 October 2009

Hydrogen Peroxide Triggers a Dual Signaling Axis To Selectively Suppress Activated Human T Lymphocyte Migration.

artículo científico publicado en 2017

Inhibition by staurosporine of mitogen-induced calcium mobilisation in human T lymphoblasts

scientific article published on 01 November 1988

Inhibition of CD28-mediated T cell costimulation by the phosphoinositide 3-kinase inhibitor wortmannin

artículo científico publicado en 1995

Inhibition of PI3K signaling spurs new therapeutic opportunities in inflammatory/autoimmune diseases and hematological malignancies.

artículo científico

Interactions between phosphatidylinositol 3-kinase and nitric oxide: explaining the paradox.

artículo científico publicado en 2000

Isoform-specific phosphoinositide 3-kinase inhibitors as therapeutic agents.

artículo científico publicado en 2003

Leukocyte navigation mechanisms as targets in airway diseases.

artículo científico publicado en 2006

Ligation of CD28 stimulates the formation of a multimeric signaling complex involving grb-2-associated binder 2 (gab2), SRC homology phosphatase-2, and phosphatidylinositol 3-kinase: evidence that negative regulation of CD28 signaling requires the g

artículo científico publicado en 2006

Ligation of the T cell co-stimulatory receptor CD28 activates the serine-threonine protein kinase protein kinase B.

artículo científico publicado en 1997

Long term cannabinoid receptor (CB1) blockade in obesity: implications for the development of colorectal cancer.

artículo científico publicado en 2008

Macrophage Migration Inhibitory Factor is subjected to glucose modification and oxidation in Alzheimer's Disease

artículo científico publicado en 2017

Mechanisms of chemokine and antigen-dependent T-lymphocyte navigation.

artículo científico publicado en 2009

Millipede-like lymphocyte crawling: feeling the way with filopodia.

artículo científico publicado en 2009

Mitochondrial superoxide generation enhances P2X7R-mediated loss of cell surface CD62L on naive human CD4+ T lymphocytes.

artículo científico publicado en 2013

Modulation of P-glycoprotein activity by the substituted quinoxalinone compound QA3 in adriamycin-resistant K562/A02 cells

artículo científico publicado en 2010

New drug targets in inflammation: efforts to expand the anti-inflammatory armoury.

artículo científico publicado en 2008

New insights into mechanisms of gastrointestinal inflammation and cancer

artículo científico publicado en 2009

Nitric oxide in inflammatory bowel disease: a universal messenger in an unsolved puzzle.

artículo científico publicado en 2004

Optimal chemotactic responses of leukemic T cells to stromal cell-derived factor-1 requires the activation of both class IA and IB phosphoinositide 3-kinases.

artículo científico publicado en 2003

PI 3-K and T-cell activation: limitations of T-leukemic cell lines as signaling models.

artículo científico publicado en 2001

PI 3-kinase: a pivotal pathway in T-cell activation?

artículo científico publicado en 1996

PI3K comes of age

artículo científico publicado en 2003

PI3K inhibitors as potential therapeutics for autoimmune disease

artículo científico

PI3Kgamma is the dominant isoform involved in migratory responses of human T lymphocytes: effects of ex vivo maintenance and limitations of non-viral delivery of siRNA.

artículo científico publicado en 2007

Phosphoinositide 3-kinase alpha-dependent regulation of branching morphogenesis in murine embryonic lung: evidence for a role in determining morphogenic properties of FGF7

artículo científico publicado en 2014

Phosphoinositide 3-kinase signalling in lung disease: leucocytes and beyond.

artículo científico publicado en 2007

Phosphoinositide 3-kinase: a key biochemical signal for cell migration in response to chemokines.

artículo científico publicado en 2000

Phosphoinositide 3-kinases in T lymphocyte activation

artículo científico publicado en 2001

Phosphoinositide 3-kinases in the gut: a link between inflammation and cancer?

artículo científico publicado en 2001

Phosphoinositide lipid phosphatases: natural regulators of phosphoinositide 3-kinase signaling in T lymphocytes

artículo científico publicado en 2007

Protein arginine methylation: a new handle on T lymphocytes?

artículo científico publicado en 2010

Regulatory role of phosphatidylinositol 3-kinase on TNF-alpha-induced cyclooxygenase 2 expression in colonic epithelial cells.

artículo científico publicado en 2001

Sat-Nav for T cells: Role of PI3K isoforms and lipid phosphatases in migration of T lymphocytes ⬇️

artículo científico publicado el 17 de febrero de 2011

Small molecule inhibitors that discriminate between protein arginine N-methyltransferases PRMT1 and CARM1.

artículo científico publicado en 2011

Spotlight on new anti-inflammatory drug targets in the immune system

artículo científico publicado en 2003

Spurs in the hunt for new immunomodulatory drug targets.

artículo científico publicado en 2012

T lymphocytes on the move: chemokines, PI 3-kinase and beyond

artículo científico publicado en 2006

T-lymphocyte navigation and migration: beyond the PI3K paradigm

artículo científico publicado en 2007

Targeting PI3K isoforms and SHIP in the immune system: new therapeutics for inflammation and leukemia.

artículo científico publicado en 2012

Temporal variation in CB2R levels following T lymphocyte activation: Evidence that cannabinoids modulate CXCL12-induced chemotaxis

article

The CC chemokine monocyte chemotactic peptide-1 activates both the class I p85/p110 phosphatidylinositol 3-kinase and the class II PI3K-C2alpha.

artículo científico publicado en 1998

The PI3K inhibitor arsenal: choose your weapon!

artículo científico publicado en 2007

The Role of Ubiquitination and Hepatocyte Growth Factor-Regulated Tyrosine Kinase Substrate in the Degradation of the Adrenomedullin Type I Receptor

artículo científico publicado en 2017

Therapeutic potential of phosphoinositide 3-kinase inhibitors.

artículo científico publicado en 2003

Time resolved amplified FRET identifies protein kinase B activation state as a marker for poor prognosis in clear cell renal cell carcinoma.

artículo científico publicado en 2017

Toll-like receptors in the spotlight

scientific article published on 01 April 2003

Toward the development of potent and selective bisubstrate inhibitors of protein arginine methyltransferases.

artículo científico publicado en 2010

Lista de obras de Stephen G Ward

Activation of phosphatidylinositol 3-kinase by interleukin-13. An inhibitory signal for inducible nitric-oxide synthase expression in epithelial cell line HT-29.

Activation of the PI3K effector protein kinase B following ligation of CD28 or Fas

Analysis of CXCR3 and atypical variant expression and signalling in human T lymphocytes.

Antagonism of the platelet activating factor-induced rise of the intracellular calcium ion concentration of U937 cells ⬇️

Antibody ligation of CD7 leads to association with phosphoinositide 3-kinase and phosphatidylinositol 3,4,5-trisphosphate formation in T lymphocytes

Both CD28 ligands CD80 (B7-1) and CD86 (B7-2) activate phosphatidylinositol 3-kinase, and wortmannin reveals heterogeneity in the regulation of T cell IL-2 secretion.

CD28 stimulates tyrosine phosphorylation, cellular redistribution and catalytic activity of the inositol lipid 5-phosphatase SHIP

CD28: a signalling perspective.

Chemokines and T lymphocytes: more than an attraction

Chemokines: understanding their role in T-lymphocyte biology.

Comparison of infrared thermography and laser speckle contrast imaging for the dynamic assessment of digital microvascular function.

Des-gamma-carboxy prothrombin stimulates human vascular endothelial cell growth and migration.

Development and characterisation of tetracycline-regulated phosphoinositide 3-kinase mutants: assessing the role of multiple phosphoinositide 3-kinases in chemokine signaling.

Differential modulation of COX-2 expression in A549 airway epithelial cells by structurally distinct PPAR(gamma) agonists: evidence for disparate functional effects which are independent of NF-(kappa)B and PPAR(gamma).

Differential regulation of prostaglandin E biosynthesis by interferon-gamma in colonic epithelial cells

Evidence that SHIP-1 contributes to phosphatidylinositol 3,4,5-trisphosphate metabolism in T lymphocytes and can regulate novel phosphoinositide 3-kinase effectors

Evidence that a kinase distinct from protein kinase C and phosphatidylinositol 3-kinase mediates ligation-dependent serine/threonine phosphorylation of the T-lymphocyte co-stimulatory molecule CD28.

Evidence that phospholipase-C-dependent, calcium-independent mechanisms are required for directional migration of T-lymphocytes in response to the CCR4 ligands CCL17 and CCL22.

Evidence that the lipid phosphatase SHIP-1 regulates T lymphocyte morphology and motility

Expression and agonist responsiveness of CXCR3 variants in human T lymphocytes.

Fine tuning T lymphocytes: a role for the lipid phosphatase SHIP-1.

Genetic ablation of PI3Kγ results in defective IL-17RA signalling in T lymphocytes and increased IL-17 levels

Heterologous regulation of chemokine receptor signaling by the lipid phosphatase SHIP in lymphocytes.

High PD-1/PD-L1 checkpoint interaction infers tumor selection and therapeutic sensitivity to anti-PD-1/PD-L1 treatment

Hnf4α is a key gene that can generate columnar metaplasia in oesophageal epithelium.

How does inflammation cause Barrett's metaplasia?

Hydrogen Peroxide Triggers a Dual Signaling Axis To Selectively Suppress Activated Human T Lymphocyte Migration.

Inhibition by staurosporine of mitogen-induced calcium mobilisation in human T lymphoblasts

Inhibition of CD28-mediated T cell costimulation by the phosphoinositide 3-kinase inhibitor wortmannin

Inhibition of PI3K signaling spurs new therapeutic opportunities in inflammatory/autoimmune diseases and hematological malignancies.

Interactions between phosphatidylinositol 3-kinase and nitric oxide: explaining the paradox.

Isoform-specific phosphoinositide 3-kinase inhibitors as therapeutic agents.

Leukocyte navigation mechanisms as targets in airway diseases.

Ligation of CD28 stimulates the formation of a multimeric signaling complex involving grb-2-associated binder 2 (gab2), SRC homology phosphatase-2, and phosphatidylinositol 3-kinase: evidence that negative regulation of CD28 signaling requires the g

Ligation of the T cell co-stimulatory receptor CD28 activates the serine-threonine protein kinase protein kinase B.

Long term cannabinoid receptor (CB1) blockade in obesity: implications for the development of colorectal cancer.

Macrophage Migration Inhibitory Factor is subjected to glucose modification and oxidation in Alzheimer's Disease

Mechanisms of chemokine and antigen-dependent T-lymphocyte navigation.

Millipede-like lymphocyte crawling: feeling the way with filopodia.

Mitochondrial superoxide generation enhances P2X7R-mediated loss of cell surface CD62L on naive human CD4+ T lymphocytes.

Modulation of P-glycoprotein activity by the substituted quinoxalinone compound QA3 in adriamycin-resistant K562/A02 cells

New drug targets in inflammation: efforts to expand the anti-inflammatory armoury.

New insights into mechanisms of gastrointestinal inflammation and cancer

Nitric oxide in inflammatory bowel disease: a universal messenger in an unsolved puzzle.

Optimal chemotactic responses of leukemic T cells to stromal cell-derived factor-1 requires the activation of both class IA and IB phosphoinositide 3-kinases.

PI 3-K and T-cell activation: limitations of T-leukemic cell lines as signaling models.

PI 3-kinase: a pivotal pathway in T-cell activation?

PI3K comes of age

PI3K inhibitors as potential therapeutics for autoimmune disease

PI3Kgamma is the dominant isoform involved in migratory responses of human T lymphocytes: effects of ex vivo maintenance and limitations of non-viral delivery of siRNA.

Phosphoinositide 3-kinase alpha-dependent regulation of branching morphogenesis in murine embryonic lung: evidence for a role in determining morphogenic properties of FGF7

Phosphoinositide 3-kinase signalling in lung disease: leucocytes and beyond.

Phosphoinositide 3-kinase: a key biochemical signal for cell migration in response to chemokines.

Phosphoinositide 3-kinases in T lymphocyte activation

Phosphoinositide 3-kinases in the gut: a link between inflammation and cancer?

Phosphoinositide lipid phosphatases: natural regulators of phosphoinositide 3-kinase signaling in T lymphocytes

Protein arginine methylation: a new handle on T lymphocytes?

Regulatory role of phosphatidylinositol 3-kinase on TNF-alpha-induced cyclooxygenase 2 expression in colonic epithelial cells.

Sat-Nav for T cells: Role of PI3K isoforms and lipid phosphatases in migration of T lymphocytes ⬇️

Small molecule inhibitors that discriminate between protein arginine N-methyltransferases PRMT1 and CARM1.

Spotlight on new anti-inflammatory drug targets in the immune system

Spurs in the hunt for new immunomodulatory drug targets.

T lymphocytes on the move: chemokines, PI 3-kinase and beyond

T-lymphocyte navigation and migration: beyond the PI3K paradigm

Targeting PI3K isoforms and SHIP in the immune system: new therapeutics for inflammation and leukemia.

Temporal variation in CB2R levels following T lymphocyte activation: Evidence that cannabinoids modulate CXCL12-induced chemotaxis

The CC chemokine monocyte chemotactic peptide-1 activates both the class I p85/p110 phosphatidylinositol 3-kinase and the class II PI3K-C2alpha.

The PI3K inhibitor arsenal: choose your weapon!

The Role of Ubiquitination and Hepatocyte Growth Factor-Regulated Tyrosine Kinase Substrate in the Degradation of the Adrenomedullin Type I Receptor

Therapeutic potential of phosphoinositide 3-kinase inhibitors.

Time resolved amplified FRET identifies protein kinase B activation state as a marker for poor prognosis in clear cell renal cell carcinoma.

Toll-like receptors in the spotlight

Toward the development of potent and selective bisubstrate inhibitors of protein arginine methyltransferases.