Lista de obras - Alastair W Poole - Dominio Público Uruguay

Absence of platelet phenotype in mice lacking the motor protein myosin Va

artículo científico publicado en 2013

Antibody cross-linking of human platelet P-selectin induces calcium entry by a mechanism dependent upon Fcgamma receptor IIA

scientific article published on 01 September 2004

Antiplatelet effects of dietary nitrate in healthy volunteers: involvement of cGMP and influence of sex.

artículo científico publicado en 2013

Aquaporin-1 regulates platelet procoagulant membrane dynamics and in vivo thrombosis.

artículo científico publicado en 2018

Bcl-xL-inhibitory BH3 mimetic ABT-737 depletes platelet calcium stores

artículo científico publicado en 2012

Canonical Wnt signaling negatively regulates platelet function

scientific journal article

Carbonic Anhydrase Inhibitors suppress platelet procoagulant responses and in vivo thrombosis

artículo científico publicado en 2020

Characterization of a novel focal adhesion kinase inhibitor in human platelets.

artículo científico publicado en 2009

Chloride channels are necessary for full platelet phosphatidylserine exposure and procoagulant activity.

artículo científico publicado en 2013

Comment on "Platelet-derived nucleotides promote tumor cell transendothelial migration and metastasis via P2Y2 receptor" by Schumacher et al

scientific article published on 01 September 2013

Coordinated Membrane Ballooning and Procoagulant Spreading in Human Platelets.

artículo científico publicado en 2015

Cracking the platelet WIP

artículo científico publicado en 2009

Critical roles for the actin cytoskeleton and cdc42 in regulating platelet integrin alpha2beta1.

artículo científico publicado en 2008

Cytohesin-2 phosphorylation by protein kinase C relieves the constitutive suppression of platelet dense granule secretion by ADP-ribosylation factor 6.

artículo científico publicado en 2014

Distinct clathrin-coated pits sort different G protein-coupled receptor cargo.

artículo científico publicado en 2006

Distinct roles for protein kinase C isoforms in regulating platelet purinergic receptor function

artículo científico publicado en 2006

Diverse functions of protein kinase C isoforms in platelet activation and thrombus formation.

artículo científico publicado en 2009

Do platelets promote cardiac recovery post myocardial infarction: Roles beyond occlusive ischemic damage.

artículo científico publicado en 2018

Dual regulation of glycogen synthase kinase 3 (GSK3)α/β by protein kinase C (PKC)α and Akt promotes thrombin-mediated integrin αIIbβ3 activation and granule secretion in platelets.

artículo científico publicado en 2012

Dysfunction of the PI3 kinase/Rap1/integrin α(IIb)β(3) pathway underlies ex vivo platelet hypoactivity in essential thrombocythemia

artículo científico publicado en 2012

Epigenetic Regulation of Associates With Myocardial Infarction and Platelet Function

artículo científico publicado en 2022

Erratum to "Antiplatelet effects of dietary nitrate in healthy volunteers: Involvement of cGMP and influence of sex" [Free Radic. Biol. Med. 65 (2013) 1521-1532].

artículo científico publicado en 2015

Evidence that the purinergic receptor P2Y12 potentiates platelet shape change by a Rho kinase-dependent mechanism.

artículo científico publicado en 2005

Focusing on the role of platelets in immune defence against invading pathogens

artículo científico publicado en 2015

Functional divergence of platelet protein kinase C (PKC) isoforms in thrombus formation on collagen.

artículo científico publicado en 2010

Functional interaction of protein kinase Calpha with the tyrosine kinases Syk and Src in human platelets.

artículo científico publicado en 2004

GPIb potentiates GPVI-induced responses in human platelets.

artículo científico publicado en 2004

Genetic analysis of the role of protein kinase Ctheta in platelet function and thrombus formation

artículo científico publicado en 2008

Identification of roles for the SNARE-associated protein, SNAP29, in mouse platelets

artículo científico publicado en 2015

Intracellular Trafficking, Localization, and Mobilization of Platelet-Borne Thiol Isomerases.

artículo científico publicado en 2016

Is JAK2V617F finally off the hook?

artículo científico publicado en 2014

Isoform-specific functions of protein kinase C: the platelet paradigm.

artículo científico publicado en 2007

Leukemia-associated Rho guanine-nucleotide exchange factor is not critical for RhoA regulation, yet is important for platelet activation and thrombosis in mice.

artículo científico

Loss of the insulin receptor in murine megakaryocytes/platelets causes thrombocytosis and alterations in IGF signalling.

artículo científico publicado en 2015

Loss of the mitochondrial kinase PINK1 does not alter platelet function

scientific article published in Scientific Reports

Mouse Platelet Ral GTPases Control P-Selectin Surface Expression, Regulating Platelet-Leukocyte Interaction.

artículo científico publicado en 2018

Multiple membrane extrusion sites drive megakaryocyte migration into bone marrow blood vessels

artículo científico publicado en 2018

Munc13-4 is critical for thrombosis through regulating release of ADP from platelets

scientific article published on 01 April 2013

Networks of enzymatically oxidized membrane lipids support calcium-dependent coagulation factor binding to maintain hemostasis.

artículo científico publicado en 2017

P2Y1 and P2Y12 receptors for ADP desensitize by distinct kinase-dependent mechanisms.

artículo científico publicado en 2005

PKCalpha regulates platelet granule secretion and thrombus formation in mice

artículo científico publicado en 2009

PKCdelta regulates collagen-induced platelet aggregation through inhibition of VASP-mediated filopodia formation

artículo científico publicado en 2006

PKCtheta in platelet activation.

artículo científico publicado en 2009

PKCα negatively regulates in vitro proplatelet formation and in vivo platelet production in mice.

artículo científico publicado en 2013

Phosphoinositide 3-kinase p110α negatively regulates thrombopoietin-mediated platelet activation and thrombus formation.

artículo científico publicado en 2018

Phosphoinositide 3-kinases p110α and p110β have differential roles in insulin-like growth factor-1-mediated Akt phosphorylation and platelet priming.

artículo científico publicado en 2014

Physical and functional interaction between protein kinase C delta and Fyn tyrosine kinase in human platelets

artículo científico publicado en 2003

Platelet Rho GTPases-a focus on novel players, roles and relationships.

artículo científico publicado en 2015

Platelet Syk is a HIT target

artículo científico publicado en 2011

Platelet dense granule secretion defects may obscure α-granule secretion mechanisms: evidence from Munc13-4-deficient platelets.

artículo científico publicado en 2015

Platelet secretion: From haemostasis to wound healing and beyond

artículo científico publicado en 2014

Platelet signaling-a primer.

artículo científico publicado en 2012

Platelet-specific deletion of SNAP23 ablates granule secretion, substantially inhibiting arterial and venous thrombosis in mice

Procoagulant platelets: generation, function, and therapeutic targeting in thrombosis

artículo científico publicado en 2017

Protein kinase C alpha enhances sodium–calcium exchange during store-operated calcium entry in mouse platelets ⬇️

artículo científico publicado el 20 de noviembre de 2010

Protein kinase C mediates platelet secretion and thrombus formation through protein kinase D2

artículo científico publicado en 2011

Protein kinase Calpha: disease regulator and therapeutic target.

artículo científico publicado en 2010

Protein kinase Ctheta negatively regulates store-independent Ca2+ entry and phosphatidylserine exposure downstream of glycoprotein VI in platelets.

artículo científico publicado en 2010

Protein kinase Cα (PKCα) regulates bone architecture and osteoblast activity.

artículo científico publicado en 2014

RGD-ligand mimetic antagonists of integrin alphaIIbbeta3 paradoxically enhance GPVI-induced human platelet activation.

artículo científico publicado en 2009

Rapid resensitization of purinergic receptor function in human platelets.

artículo científico publicado en 2008

Reciprocal cross-talk between P2Y1 and P2Y12 receptors at the level of calcium signaling in human platelets.

artículo científico publicado en 2004

RhoG protein regulates platelet granule secretion and thrombus formation in mice.

scientific article published on 08 October 2013

SDF-1α is a novel autocrine activator of platelets operating through its receptor CXCR4.

artículo científico publicado en 2014

Secrets of platelet exocytosis - what do we really know about platelet secretion mechanisms?

artículo científico publicado en 2013

Small GTPases in platelet membrane trafficking

scientific article published on 26 October 2018

Store-operated calcium entry and non-capacitative calcium entry have distinct roles in thrombin-induced calcium signalling in human platelets ⬇️

artículo científico publicado el 8 de julio de 2011

Survival protein anoctamin-6 controls multiple platelet responses including phospholipid scrambling, swelling, and protein cleavage.

artículo científico publicado en 2015

Syntaxin 8 regulates platelet dense granule secretion, aggregation, and thrombus stability

artículo científico publicado en 2014

The Fc receptor gamma-chain and the tyrosine kinase Syk are essential for activation of mouse platelets by collagen

scientific journal article

The role of individual protein kinase C isoforms in mouse mast cell function and their targeting by the immunomodulatory parasitic worm product, ES-62.

artículo científico publicado en 2015

The snake venom toxin alboaggregin-A activates glycoprotein VI.

artículo científico publicado en 2001

Transient receptor potential channels function as a coincidence signal detector mediating phosphatidylserine exposure.

artículo científico publicado en 2013

Unravelling the different functions of protein kinase C isoforms in platelets.

artículo científico publicado en 2011

Using zebrafish (Danio rerio) to assess gene function in thrombus formation

scientific article published on 01 January 2012

Vasodilator-stimulated phosphoprotein (VASP) is phosphorylated on Ser157 by protein kinase C-dependent and -independent mechanisms in thrombin-stimulated human platelets.

artículo científico publicado en 2006

WNT-3a modulates platelet function by regulating small GTPase activity

artículo científico publicado en 2012

Lista de obras de Alastair W Poole

Absence of platelet phenotype in mice lacking the motor protein myosin Va

Antibody cross-linking of human platelet P-selectin induces calcium entry by a mechanism dependent upon Fcgamma receptor IIA

Antiplatelet effects of dietary nitrate in healthy volunteers: involvement of cGMP and influence of sex.

Aquaporin-1 regulates platelet procoagulant membrane dynamics and in vivo thrombosis.

Bcl-xL-inhibitory BH3 mimetic ABT-737 depletes platelet calcium stores

Canonical Wnt signaling negatively regulates platelet function

Carbonic Anhydrase Inhibitors suppress platelet procoagulant responses and in vivo thrombosis

Characterization of a novel focal adhesion kinase inhibitor in human platelets.

Chloride channels are necessary for full platelet phosphatidylserine exposure and procoagulant activity.

Comment on "Platelet-derived nucleotides promote tumor cell transendothelial migration and metastasis via P2Y2 receptor" by Schumacher et al

Coordinated Membrane Ballooning and Procoagulant Spreading in Human Platelets.

Cracking the platelet WIP

Critical roles for the actin cytoskeleton and cdc42 in regulating platelet integrin alpha2beta1.

Cytohesin-2 phosphorylation by protein kinase C relieves the constitutive suppression of platelet dense granule secretion by ADP-ribosylation factor 6.

Distinct clathrin-coated pits sort different G protein-coupled receptor cargo.

Distinct roles for protein kinase C isoforms in regulating platelet purinergic receptor function

Diverse functions of protein kinase C isoforms in platelet activation and thrombus formation.

Do platelets promote cardiac recovery post myocardial infarction: Roles beyond occlusive ischemic damage.

Dual regulation of glycogen synthase kinase 3 (GSK3)α/β by protein kinase C (PKC)α and Akt promotes thrombin-mediated integrin αIIbβ3 activation and granule secretion in platelets.

Dysfunction of the PI3 kinase/Rap1/integrin α(IIb)β(3) pathway underlies ex vivo platelet hypoactivity in essential thrombocythemia

Epigenetic Regulation of Associates With Myocardial Infarction and Platelet Function

Erratum to "Antiplatelet effects of dietary nitrate in healthy volunteers: Involvement of cGMP and influence of sex" [Free Radic. Biol. Med. 65 (2013) 1521-1532].

Evidence that the purinergic receptor P2Y12 potentiates platelet shape change by a Rho kinase-dependent mechanism.

Focusing on the role of platelets in immune defence against invading pathogens

Functional divergence of platelet protein kinase C (PKC) isoforms in thrombus formation on collagen.

Functional interaction of protein kinase Calpha with the tyrosine kinases Syk and Src in human platelets.

GPIb potentiates GPVI-induced responses in human platelets.

Genetic analysis of the role of protein kinase Ctheta in platelet function and thrombus formation

Identification of roles for the SNARE-associated protein, SNAP29, in mouse platelets

Intracellular Trafficking, Localization, and Mobilization of Platelet-Borne Thiol Isomerases.

Is JAK2V617F finally off the hook?

Isoform-specific functions of protein kinase C: the platelet paradigm.

Leukemia-associated Rho guanine-nucleotide exchange factor is not critical for RhoA regulation, yet is important for platelet activation and thrombosis in mice.

Loss of the insulin receptor in murine megakaryocytes/platelets causes thrombocytosis and alterations in IGF signalling.

Loss of the mitochondrial kinase PINK1 does not alter platelet function

Mouse Platelet Ral GTPases Control P-Selectin Surface Expression, Regulating Platelet-Leukocyte Interaction.

Multiple membrane extrusion sites drive megakaryocyte migration into bone marrow blood vessels

Munc13-4 is critical for thrombosis through regulating release of ADP from platelets

Networks of enzymatically oxidized membrane lipids support calcium-dependent coagulation factor binding to maintain hemostasis.

P2Y1 and P2Y12 receptors for ADP desensitize by distinct kinase-dependent mechanisms.

PKCalpha regulates platelet granule secretion and thrombus formation in mice

PKCdelta regulates collagen-induced platelet aggregation through inhibition of VASP-mediated filopodia formation

PKCtheta in platelet activation.

PKCα negatively regulates in vitro proplatelet formation and in vivo platelet production in mice.

Phosphoinositide 3-kinase p110α negatively regulates thrombopoietin-mediated platelet activation and thrombus formation.

Phosphoinositide 3-kinases p110α and p110β have differential roles in insulin-like growth factor-1-mediated Akt phosphorylation and platelet priming.

Physical and functional interaction between protein kinase C delta and Fyn tyrosine kinase in human platelets

Platelet Rho GTPases-a focus on novel players, roles and relationships.

Platelet Syk is a HIT target

Platelet dense granule secretion defects may obscure α-granule secretion mechanisms: evidence from Munc13-4-deficient platelets.

Platelet secretion: From haemostasis to wound healing and beyond

Platelet signaling-a primer.

Platelet-specific deletion of SNAP23 ablates granule secretion, substantially inhibiting arterial and venous thrombosis in mice

Procoagulant platelets: generation, function, and therapeutic targeting in thrombosis

Protein kinase C alpha enhances sodium–calcium exchange during store-operated calcium entry in mouse platelets ⬇️

Protein kinase C mediates platelet secretion and thrombus formation through protein kinase D2

Protein kinase Calpha: disease regulator and therapeutic target.

Protein kinase Ctheta negatively regulates store-independent Ca2+ entry and phosphatidylserine exposure downstream of glycoprotein VI in platelets.

Protein kinase Cα (PKCα) regulates bone architecture and osteoblast activity.

RGD-ligand mimetic antagonists of integrin alphaIIbbeta3 paradoxically enhance GPVI-induced human platelet activation.

Rapid resensitization of purinergic receptor function in human platelets.

Reciprocal cross-talk between P2Y1 and P2Y12 receptors at the level of calcium signaling in human platelets.

RhoG protein regulates platelet granule secretion and thrombus formation in mice.

SDF-1α is a novel autocrine activator of platelets operating through its receptor CXCR4.

Secrets of platelet exocytosis - what do we really know about platelet secretion mechanisms?

Small GTPases in platelet membrane trafficking

Store-operated calcium entry and non-capacitative calcium entry have distinct roles in thrombin-induced calcium signalling in human platelets ⬇️

Survival protein anoctamin-6 controls multiple platelet responses including phospholipid scrambling, swelling, and protein cleavage.

Syntaxin 8 regulates platelet dense granule secretion, aggregation, and thrombus stability

The Fc receptor gamma-chain and the tyrosine kinase Syk are essential for activation of mouse platelets by collagen

The role of individual protein kinase C isoforms in mouse mast cell function and their targeting by the immunomodulatory parasitic worm product, ES-62.

The snake venom toxin alboaggregin-A activates glycoprotein VI.

Transient receptor potential channels function as a coincidence signal detector mediating phosphatidylserine exposure.

Unravelling the different functions of protein kinase C isoforms in platelets.

Using zebrafish (Danio rerio) to assess gene function in thrombus formation

Vasodilator-stimulated phosphoprotein (VASP) is phosphorylated on Ser157 by protein kinase C-dependent and -independent mechanisms in thrombin-stimulated human platelets.

WNT-3a modulates platelet function by regulating small GTPase activity