Lista de obras - Hiroshi Iwasaki - Dominio Público Uruguay

A DNA polymerase alpha accessory protein, Mcl1, is required for propagation of centromere structures in fission yeast

artículo científico publicado en 2008

A yeast gene, MGS1, encoding a DNA-dependent AAA(+) ATPase is required to maintain genome stability.

artículo científico publicado en 2001

Abortive recombination in Escherichia coli ruv mutants blocks chromosome partitioning ⬇️

artículo científico publicado el 1 de abril de 1998

An in vitro assay for monitoring the formation and branch migration of holliday junctions mediated by a eukaryotic recombinase

artículo científico publicado en 2011

Analysis of substrate specificity of the RuvC holliday junction resolvase with synthetic Holliday junctions.

artículo científico publicado en 1996

Aphidicolin inhibits DNA polymerizing activity but not nucleolytic activity of Escherichia coli DNA polymerase II

scientific article published on 01 February 1992

Atomic structure of the RuvC resolvase: a holliday junction-specific endonuclease from E. coli

artículo científico publicado en 1994

Cell polarity in Saccharomyces cerevisiae depends on proper localization of the Bud9 landmark protein by the EKC/KEOPS complex.

artículo científico

Characterisation of an intrinsically disordered protein complex of Swi5–Sfr1 by ion mobility mass spectrometry and small-angle X-ray scattering ⬇️

artículo científico publicado el 7 de marzo de 2013

Cleavage of symmetric immobile DNA junctions by Escherichia coli RuvC

artículo científico publicado en 2000

Competition between the Rad50 complex and the Ku heterodimer reveals a role for Exo1 in processing double-strand breaks but not telomeres

artículo científico publicado en 2003

Cooperative interactions facilitate stimulation of Rad51 by the Swi5-Sfr1 auxiliary factor complex

scientific article published on 24 March 2020

Crystal structure of the Holliday junction DNA in complex with a single RuvA tetramer

artículo científico publicado en 2000

Crystal structure of the RuvA-RuvB complex: a structural basis for the Holliday junction migrating motor machinery

artículo científico publicado en 2002

DNA replication machinery prevents Rad52-dependent single-strand annealing that leads to gross chromosomal rearrangements at centromeres

scientific article published on 30 April 2020

Direct evidence that a conserved arginine in RuvB AAA+ ATPase acts as an allosteric effector for the ATPase activity of the adjacent subunit in a hexamer.

artículo científico publicado en 2004

Dual regulation of Dmc1-driven DNA strand exchange by Swi5-Sfr1 activation and Rad22 inhibition

artículo científico publicado en 2013

Establishment of DNA-DNA Interactions by the Cohesin Ring

artículo científico publicado en 2018

Evidence that phenylalanine 69 in Escherichia coli RuvC resolvase forms a stacking interaction during binding and destabilization of a Holliday junction DNA substrate.

artículo científico publicado en 2001

Expression, purification and crystallization of Swi5 and the Swi5-Sfr1 complex from fission yeast

artículo científico publicado en 2010

Fission Yeast Swi5-Sfr1 Protein Complex, an Activator of Rad51 Recombinase, Forms an Extremely Elongated Dogleg-shaped Structure ⬇️

artículo científico publicado el 27 de octubre de 2011

Fission yeast Swi5/Sfr1 and Rhp55/Rhp57 differentially regulate Rhp51-dependent recombination outcomes.

artículo científico publicado en 2007

Formation and branch migration of Holliday junctions mediated by eukaryotic recombinases.

artículo científico publicado en 2008

Functional analyses of the domain structure in the Holliday junction binding protein RuvA ⬇️

artículo científico publicado el 15 de enero de 1998

Functional overlap between RecA and MgsA (RarA) in the rescue of stalled replication forks in Escherichia coli

scientific article published on 01 March 2005

Fundamental cell cycle kinases collaborate to ensure timely destruction of the synaptonemal complex during meiosis

artículo científico publicado en 2017

Genetic and physical interactions between Schizosaccharomyces pombe Mcl1 and Rad2, Dna2 and DNA polymerase alpha: evidence for a multifunctional role of Mcl1 in DNA replication and repair.

artículo científico publicado en 2005

Holliday junction resolvases mediate chloroplast nucleoid segregation

artículo científico publicado en 2017

Identification of four acidic amino acids that constitute the catalytic center of the RuvC Holliday junction resolvase.

artículo científico publicado en 1995

In vitro site-specific recombination mediated by the tyrosine recombinase XerA of Thermoplasma acidophilum.

artículo científico publicado en 2017

Involvement in DNA repair of the ruvA gene of Escherichia coli.

artículo científico publicado en 1989

Mating-type switching by homology-directed recombinational repair: a matter of choice

artículo científico publicado en 2018

Mechanistic Insights into the Activation of Rad51-Mediated Strand Exchange from the Structure of a Recombination Activator, the Swi5-Sfr1 Complex ⬇️

artículo científico publicado el 7 de marzo de 2012

Molecular analysis of the Pseudomonas aeruginosa genes, ruvA, ruvB and ruvC, involved in processing of homologous recombination intermediates.

artículo científico publicado en 1996

Molecular characterization of the Schizosaccharomyces pombe nbs1+ gene involved in DNA repair and telomere maintenance

artículo científico publicado en 2003

Molecular characterization of the role of the Schizosaccharomyces pombe nip1+/ctp1+ gene in DNA double-strand break repair in association with the Mre11-Rad50-Nbs1 complex.

artículo científico publicado en 2008

Molecular mechanisms of Holliday junction processing in Escherichia coli.

artículo científico publicado en 1995

Multiple regulation of Rad51-mediated homologous recombination by fission yeast Fbh1.

artículo científico publicado en 2014

Mutational analysis of the functional motifs of RuvB, an AAA+ class helicase and motor protein for holliday junction branch migration

artículo científico publicado en 2000

Mutational analysis on structure-function relationship of a holliday junction specific endonuclease RuvC

artículo científico publicado en 1998

Nbs1 Flexibly Tethers Ctp1 and Mre11-Rad50 to Coordinate DNA Double-Strand Break Processing and Repair

artículo científico publicado en 2009

New insights into donor directionality of mating-type switching in Schizosaccharomyces pombe.

artículo científico publicado en 2018

No braiding of Holliday junctions in positively supercoiled DNA molecules

artículo científico publicado en 1999

Opposing role of condensin hinge against replication protein A in mitosis and interphase through promoting DNA annealing ⬇️

artículo científico publicado el 1 de diciembre de 2011

Overproduction of human immunodeficiency virus type I reverse transcriptase in Escherichia coli and purification of the enzyme.

artículo científico publicado en 1990

Parallel symmetric immobile DNA junctions as substrates for E. coli RuvC Holliday junction resolvase

artículo científico publicado en 2002

Proteolytic processing of MucA protein in SOS mutagenesis: both processed and unprocessed MucA may be active in the mutagenesis.

artículo científico publicado en 1990

RAD6-RAD18-RAD5-pathway-dependent tolerance to chronic low-dose ultraviolet light.

artículo científico publicado en 2008

Rad62 protein functionally and physically associates with the smc5/smc6 protein complex and is required for chromosome integrity and recombination repair in fission yeast

artículo científico publicado en 2004

Real-time Observation of the DNA Strand Exchange Reaction Mediated by Rad51

scientific article published on 13 February 2019

Real-time tracking reveals catalytic roles for the two DNA binding sites of Rad51

scientific article published on 11 June 2020

RecA protein-dependent cleavage of UmuD protein and SOS mutagenesis.

artículo científico publicado en 1988

RecA requires two molecules of Mg2+ ions for its optimal strand exchange activity in vitro

artículo científico publicado en 2018

Reconstitution of DNA strand exchange mediated by Rhp51 recombinase and two mediators

artículo científico publicado en 2008

Reconstitution, morphology and crystallization of a fatty acid β-oxidation multienzyme complex from Pseudomonas fragi ⬇️

artículo científico publicado el 15 de diciembre de 1997

Recruitment and delivery of the fission yeast Rst2 transcription factor via a local genome structure counteracts repression by Tup1-family corepressors.

artículo científico publicado en 2017

Role of the Escherichia coli RecQ DNA helicase in SOS signaling and genome stabilization at stalled replication forks.

artículo científico publicado en 2004

Role of the RuvAB protein in avoiding spontaneous formation of deletion mutations in the Escherichia coli K-12 endogenous tonB gene

article

Role of the Schizosaccharomyces pombe F-Box DNA helicase in processing recombination intermediates

artículo científico publicado en 2005

Role of walker motif A of RuvB protein in promoting branch migration of holliday junctions. Walker motif a mutations affect Atp binding, Atp hydrolyzing, and DNA binding activities of Ruvb

artículo científico publicado en 1999

Roles of the recG gene product of Escherichia coli in recombination repair: effects of the delta recG mutation on cell division and chromosome partition.

artículo científico publicado en 1997

SOS-inducible DNA polymerase II of E coli is homologous to replicative DNA polymerase of eukaryotes.

artículo científico publicado en 1991

SOS-inducible DNA repair proteins, RuvA and RuvB, of Escherichia coli: functional interactions between RuvA and RuvB for ATP hydrolysis and renaturation of the cruciform structure in supercoiled DNA ⬇️

artículo científico publicado el 1 de octubre de 1991

Srs2 plays a critical role in reversible G2 arrest upon chronic and low doses of UV irradiation via two distinct homologous recombination-dependent mechanisms in postreplication repair-deficient cells.

artículo científico publicado en 2010

Structure and regulation of the Escherichia coli ruv operon involved in DNA repair and recombination.

artículo científico publicado en 1988

Swi5-Sfr1 protein stimulates Rad51-mediated DNA strand exchange reaction through organization of DNA bases in the presynaptic filament.

artículo científico publicado en 2013

Swi5-Sfr1 stimulates Rad51 recombinase filament assembly by modulating Rad51 dissociation

artículo científico publicado en 2018

The Gene Is Essential for Repairing Double-Strand DNA Breaks Spontaneously Occurring during Replication and Induced by DNA-Damaging Agents

The 4th International Symposium on 3R; DNA replication, recombination and repair

artículo científico publicado en 2004

The Schizosaccharomyces pombe rad60 gene is essential for repairing double-strand DNA breaks spontaneously occurring during replication and induced by DNA-damaging agents.

artículo científico publicado en 2002

The Swi5-Sfr1 complex stimulates Rhp51/Rad51- and Dmc1-mediated DNA strand exchange in vitro.

artículo científico publicado en 2006

The differentiated and conserved roles of Swi5-Sfr1 in homologous recombination.

artículo científico publicado en 2017

The fission yeast meiosis-specific Dmc1 recombinase mediates formation and branch migration of Holliday junctions by preferentially promoting strand exchange in a direction opposite to that of Rad51.

artículo científico publicado en 2011

Two auxiliary factors promote Dmc1-driven DNA strand exchange via stepwise mechanisms

scientific article published on 15 May 2020

Two basic residues, Lys-107 and Lys-118, of RuvC resolvase are involved in critical contacts with the Holliday junction for its resolution

scientific article published on 01 October 2000

Two different Swi5-containing protein complexes are involved in mating-type switching and recombination repair in fission yeast

artículo científico publicado en 2003

Two different oligomeric states of the RuvB branch migration motor protein as revealed by electron microscopy

artículo científico publicado en 2000

Two three-strand intermediates are processed during Rad51-driven DNA strand exchange

artículo científico publicado en 2017

Uncoupling of the ATPase activity from the branch migration activity of RuvAB protein complexes containing both wild-type and ATPase-defective RuvB proteins

artículo científico publicado en 2003

p53 blocks RuvAB promoted branch migration and modulates resolution of Holliday junctions by RuvC.

artículo científico publicado en 2002

Lista de obras de Hiroshi Iwasaki

A DNA polymerase alpha accessory protein, Mcl1, is required for propagation of centromere structures in fission yeast

A yeast gene, MGS1, encoding a DNA-dependent AAA(+) ATPase is required to maintain genome stability.

Abortive recombination in Escherichia coli ruv mutants blocks chromosome partitioning ⬇️

An in vitro assay for monitoring the formation and branch migration of holliday junctions mediated by a eukaryotic recombinase

Analysis of substrate specificity of the RuvC holliday junction resolvase with synthetic Holliday junctions.

Aphidicolin inhibits DNA polymerizing activity but not nucleolytic activity of Escherichia coli DNA polymerase II

Atomic structure of the RuvC resolvase: a holliday junction-specific endonuclease from E. coli

Cell polarity in Saccharomyces cerevisiae depends on proper localization of the Bud9 landmark protein by the EKC/KEOPS complex.

Characterisation of an intrinsically disordered protein complex of Swi5–Sfr1 by ion mobility mass spectrometry and small-angle X-ray scattering ⬇️

Cleavage of symmetric immobile DNA junctions by Escherichia coli RuvC

Competition between the Rad50 complex and the Ku heterodimer reveals a role for Exo1 in processing double-strand breaks but not telomeres

Cooperative interactions facilitate stimulation of Rad51 by the Swi5-Sfr1 auxiliary factor complex

Crystal structure of the Holliday junction DNA in complex with a single RuvA tetramer

Crystal structure of the RuvA-RuvB complex: a structural basis for the Holliday junction migrating motor machinery

DNA replication machinery prevents Rad52-dependent single-strand annealing that leads to gross chromosomal rearrangements at centromeres

Direct evidence that a conserved arginine in RuvB AAA+ ATPase acts as an allosteric effector for the ATPase activity of the adjacent subunit in a hexamer.

Dual regulation of Dmc1-driven DNA strand exchange by Swi5-Sfr1 activation and Rad22 inhibition

Establishment of DNA-DNA Interactions by the Cohesin Ring

Evidence that phenylalanine 69 in Escherichia coli RuvC resolvase forms a stacking interaction during binding and destabilization of a Holliday junction DNA substrate.

Expression, purification and crystallization of Swi5 and the Swi5-Sfr1 complex from fission yeast

Fission Yeast Swi5-Sfr1 Protein Complex, an Activator of Rad51 Recombinase, Forms an Extremely Elongated Dogleg-shaped Structure ⬇️

Fission yeast Swi5/Sfr1 and Rhp55/Rhp57 differentially regulate Rhp51-dependent recombination outcomes.

Formation and branch migration of Holliday junctions mediated by eukaryotic recombinases.

Functional analyses of the domain structure in the Holliday junction binding protein RuvA ⬇️

Functional overlap between RecA and MgsA (RarA) in the rescue of stalled replication forks in Escherichia coli

Fundamental cell cycle kinases collaborate to ensure timely destruction of the synaptonemal complex during meiosis

Genetic and physical interactions between Schizosaccharomyces pombe Mcl1 and Rad2, Dna2 and DNA polymerase alpha: evidence for a multifunctional role of Mcl1 in DNA replication and repair.

Holliday junction resolvases mediate chloroplast nucleoid segregation

Identification of four acidic amino acids that constitute the catalytic center of the RuvC Holliday junction resolvase.

In vitro site-specific recombination mediated by the tyrosine recombinase XerA of Thermoplasma acidophilum.

Involvement in DNA repair of the ruvA gene of Escherichia coli.

Mating-type switching by homology-directed recombinational repair: a matter of choice

Mechanistic Insights into the Activation of Rad51-Mediated Strand Exchange from the Structure of a Recombination Activator, the Swi5-Sfr1 Complex ⬇️

Molecular analysis of the Pseudomonas aeruginosa genes, ruvA, ruvB and ruvC, involved in processing of homologous recombination intermediates.

Molecular characterization of the Schizosaccharomyces pombe nbs1+ gene involved in DNA repair and telomere maintenance

Molecular characterization of the role of the Schizosaccharomyces pombe nip1+/ctp1+ gene in DNA double-strand break repair in association with the Mre11-Rad50-Nbs1 complex.

Molecular mechanisms of Holliday junction processing in Escherichia coli.

Multiple regulation of Rad51-mediated homologous recombination by fission yeast Fbh1.

Mutational analysis of the functional motifs of RuvB, an AAA+ class helicase and motor protein for holliday junction branch migration

Mutational analysis on structure-function relationship of a holliday junction specific endonuclease RuvC

Nbs1 Flexibly Tethers Ctp1 and Mre11-Rad50 to Coordinate DNA Double-Strand Break Processing and Repair

New insights into donor directionality of mating-type switching in Schizosaccharomyces pombe.

No braiding of Holliday junctions in positively supercoiled DNA molecules

Opposing role of condensin hinge against replication protein A in mitosis and interphase through promoting DNA annealing ⬇️

Overproduction of human immunodeficiency virus type I reverse transcriptase in Escherichia coli and purification of the enzyme.

Parallel symmetric immobile DNA junctions as substrates for E. coli RuvC Holliday junction resolvase

Proteolytic processing of MucA protein in SOS mutagenesis: both processed and unprocessed MucA may be active in the mutagenesis.

RAD6-RAD18-RAD5-pathway-dependent tolerance to chronic low-dose ultraviolet light.

Rad62 protein functionally and physically associates with the smc5/smc6 protein complex and is required for chromosome integrity and recombination repair in fission yeast

Real-time Observation of the DNA Strand Exchange Reaction Mediated by Rad51

Real-time tracking reveals catalytic roles for the two DNA binding sites of Rad51

RecA protein-dependent cleavage of UmuD protein and SOS mutagenesis.

RecA requires two molecules of Mg2+ ions for its optimal strand exchange activity in vitro

Reconstitution of DNA strand exchange mediated by Rhp51 recombinase and two mediators

Reconstitution, morphology and crystallization of a fatty acid β-oxidation multienzyme complex from Pseudomonas fragi ⬇️

Recruitment and delivery of the fission yeast Rst2 transcription factor via a local genome structure counteracts repression by Tup1-family corepressors.

Role of the Escherichia coli RecQ DNA helicase in SOS signaling and genome stabilization at stalled replication forks.

Role of the RuvAB protein in avoiding spontaneous formation of deletion mutations in the Escherichia coli K-12 endogenous tonB gene

Role of the Schizosaccharomyces pombe F-Box DNA helicase in processing recombination intermediates

Role of walker motif A of RuvB protein in promoting branch migration of holliday junctions. Walker motif a mutations affect Atp binding, Atp hydrolyzing, and DNA binding activities of Ruvb

Roles of the recG gene product of Escherichia coli in recombination repair: effects of the delta recG mutation on cell division and chromosome partition.

SOS-inducible DNA polymerase II of E coli is homologous to replicative DNA polymerase of eukaryotes.

SOS-inducible DNA repair proteins, RuvA and RuvB, of Escherichia coli: functional interactions between RuvA and RuvB for ATP hydrolysis and renaturation of the cruciform structure in supercoiled DNA ⬇️

Srs2 plays a critical role in reversible G2 arrest upon chronic and low doses of UV irradiation via two distinct homologous recombination-dependent mechanisms in postreplication repair-deficient cells.

Structure and regulation of the Escherichia coli ruv operon involved in DNA repair and recombination.

Swi5-Sfr1 protein stimulates Rad51-mediated DNA strand exchange reaction through organization of DNA bases in the presynaptic filament.

Swi5-Sfr1 stimulates Rad51 recombinase filament assembly by modulating Rad51 dissociation

The Gene Is Essential for Repairing Double-Strand DNA Breaks Spontaneously Occurring during Replication and Induced by DNA-Damaging Agents

The 4th International Symposium on 3R; DNA replication, recombination and repair

The Schizosaccharomyces pombe rad60 gene is essential for repairing double-strand DNA breaks spontaneously occurring during replication and induced by DNA-damaging agents.

The Swi5-Sfr1 complex stimulates Rhp51/Rad51- and Dmc1-mediated DNA strand exchange in vitro.

The differentiated and conserved roles of Swi5-Sfr1 in homologous recombination.

The fission yeast meiosis-specific Dmc1 recombinase mediates formation and branch migration of Holliday junctions by preferentially promoting strand exchange in a direction opposite to that of Rad51.

Two auxiliary factors promote Dmc1-driven DNA strand exchange via stepwise mechanisms

Two basic residues, Lys-107 and Lys-118, of RuvC resolvase are involved in critical contacts with the Holliday junction for its resolution

Two different Swi5-containing protein complexes are involved in mating-type switching and recombination repair in fission yeast

Two different oligomeric states of the RuvB branch migration motor protein as revealed by electron microscopy

Two three-strand intermediates are processed during Rad51-driven DNA strand exchange

Uncoupling of the ATPase activity from the branch migration activity of RuvAB protein complexes containing both wild-type and ATPase-defective RuvB proteins