Lista de obras - Blaise A Clarke - Dominio Público Uruguay

A Clinical and Molecular Phase II Trial of Oral ENMD-2076 in Ovarian Clear Cell Carcinoma (OCCC): A Study of the Princess Margaret Phase II Consortium

scientific article published on 14 August 2018

A Genomically Characterized Collection of High-Grade Serous Ovarian Cancer Xenografts for Preclinical Testing

artículo científico publicado en 2018

A distinct innate lymphoid cell population regulates tumor-associated T cells

artículo científico publicado en 2017

A phase I study of the combination of ro4929097 and cediranib in patients with advanced solid tumours (PJC-004/NCI 8503).

artículo científico publicado en 2013

A phase I study of the oral gamma secretase inhibitor R04929097 in combination with gemcitabine in patients with advanced solid tumors (PHL-078/CTEP 8575).

artículo científico publicado en 2013

A phase II study of single-agent RO4929097, a gamma-secretase inhibitor of Notch signaling, in patients with recurrent platinum-resistant epithelial ovarian cancer: A study of the Princess Margaret, Chicago and California phase II consortia

artículo científico publicado en 2015

A phase Ib combination study of RO4929097, a gamma-secretase inhibitor, and temsirolimus in patients with advanced solid tumors

artículo científico publicado en 2013

A triage assessment strategy for the management of women with endometrial cancer.

artículo científico

ARID1A loss correlates with mismatch repair deficiency and intact p53 expression in high-grade endometrial carcinomas

artículo científico publicado en 2013

ARID1A/BAF250a as a prognostic marker for gastric carcinoma: a study of 2 cohorts.

artículo científico publicado en 2014

Absolute lymphocyte count is associated with survival in ovarian cancer independent of tumor-infiltrating lymphocytes

artículo científico publicado en 2012

Association of Ipilimumab With Safety and Antitumor Activity in Women With Metastatic or Recurrent Human Papillomavirus-Related Cervical Carcinoma.

artículo científico publicado en 2017

Biologic rationale and clinical activity of mTOR inhibitors in gynecological cancer.

artículo científico publicado en 2012

Biologically-targeted detection of primary and micro-metastatic ovarian cancer

artículo científico publicado en 2013

Canadian Association of Pathologists-Association canadienne des pathologistes National Standards Committee for High Complexity Testing/Immunohistochemistry: guidelines for the preparation, release, and storage of unstained archived diagnostic tissue

artículo científico publicado en 2014

Canadian high risk endometrial cancer (CHREC) consortium: analyzing the clinical behavior of high risk endometrial cancers

artículo científico publicado en 2015

Cancer classification using the Immunoscore: a worldwide task force

artículo científico publicado en 2012

Characterization of the Tumor-Microenvironment in Patient-Derived Cervix Xenografts (OCICx)

artículo científico publicado en 2012

Chromosomal instability as a prognostic marker in cervical cancer

artículo científico publicado en 2015

Clear cell (glycogen-rich) gastric adenocarcinoma.

artículo científico publicado en 2004

Clinical, morphological and immunohistochemical evidence that small-cell carcinoma of the ovary of hypercalcaemic type (SCCOHT) may be a primitive germ-cell neoplasm.

artículo científico publicado en 2017

Comparison of clinical schemas and morphologic features in predicting Lynch syndrome in mutation-positive patients with endometrial cancer encountered in the context of familial gastrointestinal cancer registries.

artículo científico publicado en 2011

Cryptococcemia Resulting in an Incomplete Abortion in an HIV-Positive Patient ⬇️

artículo científico publicado el 1 de enero de 2009

Current morphologic criteria perform poorly in identifying hereditary leiomyomatosis and renal cell carcinoma syndrome-associated uterine leiomyomas

artículo científico publicado en 2014

DICER1 Mutations Are Consistently Present in Moderately and Poorly Differentiated Sertoli-Leydig Cell Tumors.

artículo científico publicado en 2017

Data set for reporting of ovary, fallopian tube and primary peritoneal carcinoma: recommendations from the International Collaboration on Cancer Reporting (ICCR)

artículo científico publicado en 2015

Developing a prognostic micro-RNA signature for human cervical carcinoma

artículo científico publicado en 2015

Displaced granulosa cells within the ovarian stroma in a BRCA1 mutation carrier

artículo científico publicado en 2014

Endometrial carcinoma: controversies in histopathological assessment of grade and tumour cell type.

artículo científico publicado en 2010

Endometrial giant cell carcinoma: a case series and review of the spectrum of endometrial neoplasms containing giant cells.

artículo científico publicado en 2010

Expanding the morphological spectrum of ovarian microcystic stromal tumour

article

Fertility sparing treatment of complex atypical hyperplasia and low grade endometrial cancer using oral progestin.

artículo científico publicado en 2014

Frequent somatic mutations of the telomerase reverse transcriptase promoter in ovarian clear cell carcinoma but not in other major types of gynaecological malignancy.

artículo científico publicado en 2014

Genotype-matched treatment for patients with advanced type I epithelial ovarian cancer (EOC).

artículo científico publicado en 2017

Germline and somatic SMARCA4 mutations characterize small cell carcinoma of the ovary, hypercalcemic type

artículo científico publicado en 2014

Gynaecological neoplasms in common familial syndromes (Lynch and HBOC).

artículo científico publicado en 2017

Gynecologic Pathology

artículo científico publicado en 2016

Hedgehog pathway signaling in cervical carcinoma and outcome after chemoradiation

artículo científico publicado en 2011

Histologic artifacts in abdominal, vaginal, laparoscopic, and robotic hysterectomy specimens: a blinded, retrospective review.

artículo científico publicado en 2011

Hormone-receptor expression and ovarian cancer survival: an Ovarian Tumor Tissue Analysis consortium study

artículo científico publicado en 2013

Hotspot activating PRKD1 somatic mutations in polymorphous low-grade adenocarcinomas of the salivary glands.

artículo científico publicado en 2014

Hypoxic activation of the PERK/eIF2α arm of the unfolded protein response promotes metastasis through induction of LAMP3.

artículo científico publicado en 2013

Identification of molecular pathway aberrations in uterine serous carcinoma by genome-wide analyses.

artículo científico publicado en 2012

Identifying Lynch syndrome in patients with ovarian carcinoma: the significance of tumor subtype.

artículo científico publicado en 2013

Implementing a Cervical Sentinel Lymph Node Biopsy Program: Quality Improvement in Gynaecologic Oncology.

artículo científico publicado en 2017

In-depth proteomics of ovarian cancer ascites: combining shotgun proteomics and selected reaction monitoring mass spectrometry.

artículo científico publicado en 2011

International Society of Gynecological Pathologists (ISGyP) Endometrial Cancer Project: Guidelines From the Special Techniques and Ancillary Studies Group

artículo científico publicado en 2018

Intraepithelial T cells and prognosis in ovarian carcinoma: novel associations with stage, tumor type and BRCA1 loss

artículo científico publicado en 2008

Intratumoral heterogeneity in a minority of ovarian low-grade serous carcinomas

artículo científico publicado en 2014

Isolated amoebic appendicitis.

artículo científico publicado en 2001

Landscape of genomic alterations in high-grade serous ovarian cancer from exceptional long- and short-term survivors

artículo científico publicado en 2018

Leiomyosarcoma of the broad ligament with osteoclast-like giant cells and rhabdoid cells.

artículo científico publicado en 2010

Letter to the editor regarding 'Roh MH, Lassin Y, Miron A et al. High-grade fimbrial-ovarian carcinomas are unified by p53, PTEN and PAX2 expression'

scientific article published on 01 September 2011

Loss of SMARCA4 (BRG1) protein expression as determined by immunohistochemistry in small-cell carcinoma of the ovary, hypercalcaemic type distinguishes these tumours from their mimics

artículo científico publicado en 2016

MicroRNA-196b regulates the homeobox B7-vascular endothelial growth factor axis in cervical cancer.

artículo científico publicado en 2013

Microsatellite analysis of early stage (Ia-IIb) uterine cervical squamous carcinoma.

artículo científico publicado en 2003

Microscopic extraovarian sex cord proliferations: an undescribed phenomenon.

artículo científico publicado en 2014

Molecular characterization of mucinous ovarian tumours supports a stratified treatment approach with HER2 targeting in 19% of carcinomas.

artículo científico publicado en 2013

Molecular determinants of outcome with mammalian target of rapamycin inhibition in endometrial cancer

artículo científico publicado en 2014

Molecular profiling and clinical outcome of high-grade serous ovarian cancer presenting with low- versus high-volume ascites

artículo científico publicado en 2014

Molecular profiling of advanced solid tumors and patient outcomes with genotype-matched clinical trials: the Princess Margaret IMPACT/COMPACT trial.

artículo científico publicado en 2016

Mutation ofFOXL2in Granulosa-Cell Tumors of the Ovary

scientific article published on 10 June 2009

Mutations inIDH1andIDH2are not present in sporadic ovarian sex cord-stromal tumours

artículo científico publicado en 2014

Myxoid invasive papillary urothelial carcinoma of the bladder and urethra

scientific article published on 01 November 2001

Müllerian adenosarcomas with unusual growth patterns: staging issues.

artículo científico publicado en 2011

Neoadjuvant Chemotherapy of Ovarian Cancer Results in Three Patterns of Tumor-Infiltrating Lymphocyte Response with Distinct Implications for Immunotherapy

artículo científico publicado en 2016

Neuroendocrine tumors of the gynecologic tract: select topics.

artículo científico

No small surprise - small cell carcinoma of the ovary, hypercalcaemic type, is a malignant rhabdoid tumour

artículo científico publicado en 2014

Novel PRKD gene rearrangements and variant fusions in cribriform adenocarcinoma of salivary gland origin.

artículo científico publicado en 2014

Novel combinations of PI3K-mTOR inhibitors with dacomitinib or chemotherapy in PTEN-deficient patient-derived tumor xenografts.

artículo científico publicado en 2017

Ovarian Microcystic Stromal Tumors Are Characterized by Alterations in the Beta-Catenin-APC Pathway and May be an Extracolonic Manifestation of Familial Adenomatous Polyposis

artículo científico publicado en 2017

Ovarian hilar proliferations resembling Sertoli cell tumours: microscopic neoplasms or non-neoplastic remnants?

artículo científico publicado en 2015

Ovarian immature teratoma: Treatment and outcome in a single institutional cohort

article

Performance characteristics of a brief Family History Questionnaire to screen for Lynch syndrome in women with newly diagnosed endometrial cancer.

artículo científico publicado en 2014

Performance characteristics of screening strategies for Lynch syndrome in unselected women with newly diagnosed endometrial cancer who have undergone universal germline mutation testing.

artículo científico publicado en 2014

Plexiform spitz nevus.

artículo científico publicado en 2002

Prevalence of loss of expression of DNA mismatch repair proteins in primary epithelial ovarian tumors.

artículo científico publicado en 2012

Primary frozen section diagnosis by robotic microscopy and virtual slide telepathology: the University Health Network experience

artículo científico publicado en 2009

Primary frozen section diagnosis by robotic microscopy and virtual slide telepathology: the University Health Network experience

artículo científico publicado en 2009

Progesterone receptor expression is associated with longer overall survival within high-grade histotypes of endometrial carcinoma: A Canadian high risk endometrial cancer consortium (CHREC) study

artículo científico publicado en 2016

Prognostic Significance of Human Papilloma Virus and p16 Expression in Patients with Vulvar Squamous Cell Carcinoma who Received Radiotherapy.

artículo científico publicado en 2018

Prophylactic Gynecologic Specimens from Hereditary Cancer Carriers

artículo científico publicado en 2016

Recurrent somatic DICER1 mutations in nonepithelial ovarian cancers

artículo científico publicado en 2011

Regulatory T Cells in Ovarian Cancer Are Characterized by a Highly Activated Phenotype Distinct from that in Melanoma

artículo científico publicado en 2018

Review of findings in prophylactic gynaecological specimens in Lynch syndrome with literature review and recommendations for grossing

artículo científico

Small cell carcinoma of the ovary, hypercalcemic type, displays frequent inactivating germline and somatic mutations in SMARCA4

artículo científico publicado en 2014

Somatic BRCA1/2 Recovery as a Resistance Mechanism After Exceptional Response to Poly (ADP-ribose) Polymerase Inhibition.

artículo científico publicado en 2017

Sorafenib Increases Tumor Hypoxia in Cervical Cancer Patients Treated With Radiation Therapy: Results of a Phase 1 Clinical Study.

artículo científico publicado en 2015

Systemic anaplastic large cell lymphoma presenting with conjunctival involvement.

artículo científico publicado en 2003

Targeting tumor hypoxia: suppression of breast tumor growth and metastasis by novel carbonic anhydrase IX inhibitors.

artículo científico publicado en 2011

The histomorphology of Lynch syndrome-associated ovarian carcinomas: toward a subtype-specific screening strategy

artículo científico

Treatment related outcomes in high-risk endometrial carcinoma: Canadian high risk endometrial cancer consortium (CHREC).

artículo científico publicado en 2016

Tubulo-squamous polyp with mucinous and goblet cell differentiation: a unique morphologic variant

artículo científico publicado en 2011

Tumor cell type can be reproducibly diagnosed and is of independent prognostic significance in patients with maximally debulked ovarian carcinoma.

artículo científico publicado en 2008

Use of mismatch repair immunohistochemistry and microsatellite instability testing: exploring Canadian practices.

artículo científico publicado en 2012

Uterine adenosarcomas: a dual-institution update on staging, prognosis and survival

artículo científico

VEPH1 expression decreases vascularisation in ovarian cancer xenografts and inhibits VEGFA and IL8 expression through inhibition of AKT activation

artículo científico publicado en 2017

Lista de obras de Blaise A Clarke

A Clinical and Molecular Phase II Trial of Oral ENMD-2076 in Ovarian Clear Cell Carcinoma (OCCC): A Study of the Princess Margaret Phase II Consortium

A Genomically Characterized Collection of High-Grade Serous Ovarian Cancer Xenografts for Preclinical Testing

A distinct innate lymphoid cell population regulates tumor-associated T cells

A phase I study of the combination of ro4929097 and cediranib in patients with advanced solid tumours (PJC-004/NCI 8503).

A phase I study of the oral gamma secretase inhibitor R04929097 in combination with gemcitabine in patients with advanced solid tumors (PHL-078/CTEP 8575).

A phase II study of single-agent RO4929097, a gamma-secretase inhibitor of Notch signaling, in patients with recurrent platinum-resistant epithelial ovarian cancer: A study of the Princess Margaret, Chicago and California phase II consortia

A phase Ib combination study of RO4929097, a gamma-secretase inhibitor, and temsirolimus in patients with advanced solid tumors

A triage assessment strategy for the management of women with endometrial cancer.

ARID1A loss correlates with mismatch repair deficiency and intact p53 expression in high-grade endometrial carcinomas

ARID1A/BAF250a as a prognostic marker for gastric carcinoma: a study of 2 cohorts.

Absolute lymphocyte count is associated with survival in ovarian cancer independent of tumor-infiltrating lymphocytes

Association of Ipilimumab With Safety and Antitumor Activity in Women With Metastatic or Recurrent Human Papillomavirus-Related Cervical Carcinoma.

Biologic rationale and clinical activity of mTOR inhibitors in gynecological cancer.

Biologically-targeted detection of primary and micro-metastatic ovarian cancer

Canadian Association of Pathologists-Association canadienne des pathologistes National Standards Committee for High Complexity Testing/Immunohistochemistry: guidelines for the preparation, release, and storage of unstained archived diagnostic tissue

Canadian high risk endometrial cancer (CHREC) consortium: analyzing the clinical behavior of high risk endometrial cancers

Cancer classification using the Immunoscore: a worldwide task force

Characterization of the Tumor-Microenvironment in Patient-Derived Cervix Xenografts (OCICx)

Chromosomal instability as a prognostic marker in cervical cancer

Clear cell (glycogen-rich) gastric adenocarcinoma.

Clinical, morphological and immunohistochemical evidence that small-cell carcinoma of the ovary of hypercalcaemic type (SCCOHT) may be a primitive germ-cell neoplasm.

Comparison of clinical schemas and morphologic features in predicting Lynch syndrome in mutation-positive patients with endometrial cancer encountered in the context of familial gastrointestinal cancer registries.

Cryptococcemia Resulting in an Incomplete Abortion in an HIV-Positive Patient ⬇️

Current morphologic criteria perform poorly in identifying hereditary leiomyomatosis and renal cell carcinoma syndrome-associated uterine leiomyomas

DICER1 Mutations Are Consistently Present in Moderately and Poorly Differentiated Sertoli-Leydig Cell Tumors.

Data set for reporting of ovary, fallopian tube and primary peritoneal carcinoma: recommendations from the International Collaboration on Cancer Reporting (ICCR)

Developing a prognostic micro-RNA signature for human cervical carcinoma

Displaced granulosa cells within the ovarian stroma in a BRCA1 mutation carrier

Endometrial carcinoma: controversies in histopathological assessment of grade and tumour cell type.

Endometrial giant cell carcinoma: a case series and review of the spectrum of endometrial neoplasms containing giant cells.

Expanding the morphological spectrum of ovarian microcystic stromal tumour

Fertility sparing treatment of complex atypical hyperplasia and low grade endometrial cancer using oral progestin.

Frequent somatic mutations of the telomerase reverse transcriptase promoter in ovarian clear cell carcinoma but not in other major types of gynaecological malignancy.

Genotype-matched treatment for patients with advanced type I epithelial ovarian cancer (EOC).

Germline and somatic SMARCA4 mutations characterize small cell carcinoma of the ovary, hypercalcemic type

Gynaecological neoplasms in common familial syndromes (Lynch and HBOC).

Gynecologic Pathology

Hedgehog pathway signaling in cervical carcinoma and outcome after chemoradiation

Histologic artifacts in abdominal, vaginal, laparoscopic, and robotic hysterectomy specimens: a blinded, retrospective review.

Hormone-receptor expression and ovarian cancer survival: an Ovarian Tumor Tissue Analysis consortium study

Hotspot activating PRKD1 somatic mutations in polymorphous low-grade adenocarcinomas of the salivary glands.

Hypoxic activation of the PERK/eIF2α arm of the unfolded protein response promotes metastasis through induction of LAMP3.

Identification of molecular pathway aberrations in uterine serous carcinoma by genome-wide analyses.

Identifying Lynch syndrome in patients with ovarian carcinoma: the significance of tumor subtype.

Implementing a Cervical Sentinel Lymph Node Biopsy Program: Quality Improvement in Gynaecologic Oncology.

In-depth proteomics of ovarian cancer ascites: combining shotgun proteomics and selected reaction monitoring mass spectrometry.

International Society of Gynecological Pathologists (ISGyP) Endometrial Cancer Project: Guidelines From the Special Techniques and Ancillary Studies Group

Intraepithelial T cells and prognosis in ovarian carcinoma: novel associations with stage, tumor type and BRCA1 loss

Intratumoral heterogeneity in a minority of ovarian low-grade serous carcinomas

Isolated amoebic appendicitis.

Landscape of genomic alterations in high-grade serous ovarian cancer from exceptional long- and short-term survivors

Leiomyosarcoma of the broad ligament with osteoclast-like giant cells and rhabdoid cells.

Letter to the editor regarding 'Roh MH, Lassin Y, Miron A et al. High-grade fimbrial-ovarian carcinomas are unified by p53, PTEN and PAX2 expression'

Loss of SMARCA4 (BRG1) protein expression as determined by immunohistochemistry in small-cell carcinoma of the ovary, hypercalcaemic type distinguishes these tumours from their mimics

MicroRNA-196b regulates the homeobox B7-vascular endothelial growth factor axis in cervical cancer.

Microsatellite analysis of early stage (Ia-IIb) uterine cervical squamous carcinoma.

Microscopic extraovarian sex cord proliferations: an undescribed phenomenon.

Molecular characterization of mucinous ovarian tumours supports a stratified treatment approach with HER2 targeting in 19% of carcinomas.

Molecular determinants of outcome with mammalian target of rapamycin inhibition in endometrial cancer

Molecular profiling and clinical outcome of high-grade serous ovarian cancer presenting with low- versus high-volume ascites

Molecular profiling of advanced solid tumors and patient outcomes with genotype-matched clinical trials: the Princess Margaret IMPACT/COMPACT trial.

Mutation ofFOXL2in Granulosa-Cell Tumors of the Ovary

Mutations inIDH1andIDH2are not present in sporadic ovarian sex cord-stromal tumours

Myxoid invasive papillary urothelial carcinoma of the bladder and urethra

Müllerian adenosarcomas with unusual growth patterns: staging issues.

Neoadjuvant Chemotherapy of Ovarian Cancer Results in Three Patterns of Tumor-Infiltrating Lymphocyte Response with Distinct Implications for Immunotherapy

Neuroendocrine tumors of the gynecologic tract: select topics.

No small surprise - small cell carcinoma of the ovary, hypercalcaemic type, is a malignant rhabdoid tumour

Novel PRKD gene rearrangements and variant fusions in cribriform adenocarcinoma of salivary gland origin.

Novel combinations of PI3K-mTOR inhibitors with dacomitinib or chemotherapy in PTEN-deficient patient-derived tumor xenografts.

Ovarian Microcystic Stromal Tumors Are Characterized by Alterations in the Beta-Catenin-APC Pathway and May be an Extracolonic Manifestation of Familial Adenomatous Polyposis

Ovarian hilar proliferations resembling Sertoli cell tumours: microscopic neoplasms or non-neoplastic remnants?

Ovarian immature teratoma: Treatment and outcome in a single institutional cohort

Performance characteristics of a brief Family History Questionnaire to screen for Lynch syndrome in women with newly diagnosed endometrial cancer.

Performance characteristics of screening strategies for Lynch syndrome in unselected women with newly diagnosed endometrial cancer who have undergone universal germline mutation testing.

Plexiform spitz nevus.

Prevalence of loss of expression of DNA mismatch repair proteins in primary epithelial ovarian tumors.

Primary frozen section diagnosis by robotic microscopy and virtual slide telepathology: the University Health Network experience

Primary frozen section diagnosis by robotic microscopy and virtual slide telepathology: the University Health Network experience