Lista de obras - Ian Chambers - Dominio Público Uruguay

A direct physical interaction between Nanog and Sox2 regulates embryonic stem cell self-renewal

scientific journal article

A distinct expression pattern in mammalian testes indicates a conserved role for NANOG in spermatogenesis.

artículo científico publicado en 2010

A new twist to Sin3 complexes in pluripotent cells

artículo científico publicado en 2017

An Oct4-centered protein interaction network in embryonic stem cells

artículo científico publicado en 2010

BMP induction of Id proteins suppresses differentiation and sustains embryonic stem cell self-renewal in collaboration with STAT3

artículo científico publicado en 2003

Characterization of the uterine phenotype during the peri-implantation period for LIF-null, MF1 strain mice.

artículo científico publicado en 2005

Complementary tissue-specific expression of LIF and LIF-receptor mRNAs in early mouse embryogenesis

scientific article published on 01 July 1996

Derivation of germline competent embryonic stem cells with a combination of interleukin-6 and soluble interleukin-6 receptor

artículo científico publicado en 1994

Dicistronic targeting constructs: reporters and modifiers of mammalian gene expression.

artículo científico publicado en 1994

Distinct Contributions of Tryptophan Residues within the Dimerization Domain to Nanog Function

artículo científico publicado en 2016

Distinct Signaling Requirements for the Establishment of ESC Pluripotency in Late-Stage EpiSCs

artículo científico publicado en 2016

Distinct SoxB1 networks are required for naïve and primed pluripotency

artículo científico publicado en 2017

Dynamic changes in Sox2 spatio-temporal expression promote the second cell fate decision through Fgf4/Fgfr2 signalling in preimplantation mouse embryos

artículo científico publicado en 2018

Effect of selenium status on mRNA levels for glutathione peroxidase in rat liver

scientific article published on 01 June 1988

Endogenous epitope-tagging of Tet1, Tet2 and Tet3 identifies TET2 as a naïve pluripotency marker

scientific article published on 03 October 2019

Engineering the mouse genome with bacterial artificial chromosomes to create multipurpose alleles.

artículo científico publicado en 2003

Esrrb Complementation Rescues Development of Nanog-Null Germ Cells

artículo científico publicado en 2018

Esrrb extinction triggers dismantling of naïve pluripotency and marks commitment to differentiation

artículo científico publicado en 2018

Estrogen-related receptor beta interacts with Oct4 to positively regulate Nanog gene expression

scientific journal article

Expression of alternative forms of differentiation inhibiting activity (DIA/LIF) during murine embryogenesis and in neonatal and adult tissues.

artículo científico publicado en 1993

Expression-independent gene trap vectors for random and targeted mutagenesis in embryonic stem cells ⬇️

scientific article published on 19 August 2009

Formation of pluripotent stem cells in the mammalian embryo depends on the POU transcription factor Oct4

artículo científico publicado en 1998

Functional Antagonism between OTX2 and NANOG Specifies a Spectrum of Heterogeneous Identities in Embryonic Stem Cells

artículo científico publicado en 2017

Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells

artículo científico publicado en 2018

Functional expression cloning of Nanog, a pluripotency sustaining factor in embryonic stem cells

artículo científico publicado en 2003

Functional gene screening in embryonic stem cells implicates Wnt antagonism in neural differentiation

artículo científico publicado en 2002

Hes1 desynchronizes differentiation of pluripotent cells by modulating STAT3 activity ⬇️

artículo científico publicado en 2013

Lessons in learning: An effective process for engaging 12- to 14-year-olds in stem cell biology

artículo científico publicado en 2014

Maintenance of the pluripotential phenotype of embryonic stem cells through direct activation of gp130 signalling pathways

scientific article published on 01 February 1994

Molecular coupling of Xist regulation and pluripotency.

artículo científico publicado en 2008

Nanog is the gateway to the pluripotent ground state.

artículo científico publicado en 2009

Nanog promotes transfer of pluripotency after cell fusion

artículo científico publicado en 2006

Nanog retrotransposed genes with functionally conserved open reading frames.

artículo científico publicado en 2006

Nanog safeguards pluripotency and mediates germline development

artículo científico publicado en 2007

OCT4/SOX2-independent Nanog autorepression modulates heterogeneous Nanog gene expression in mouse ES cells.

artículo científico publicado en 2012

Phenotypic complementation establishes requirements for specific POU domain and generic transactivation function of Oct-3/4 in embryonic stem cells.

artículo científico publicado en 2002

Quantification of Pluripotency Transcription Factor Levels in Embryonic Stem Cells by Flow Cytometry ⬇️

artículo científico publicado el 1 de diciembre de 2011

Reduced Oct4 expression directs a robust pluripotent state with distinct signaling activity and increased enhancer occupancy by Oct4 and Nanog

artículo científico publicado en 2013

Reprogramming Roadblocks Are System Dependent

artículo científico publicado en 2015

Segregation of the mouse germline and soma

scientific article published on 04 October 2019

Selective influence of Sox2 on POU transcription factor binding in embryonic and neural stem cells.

artículo científico publicado en 2015

Self-renewal of pluripotent embryonic stem cells is mediated via activation of STAT3

artículo científico publicado en 1998

Self-renewal of teratocarcinoma and embryonic stem cells.

artículo científico publicado en 2004

Signaling mechanisms regulating self-renewal and differentiation of pluripotent embryonic stem cells.

artículo científico publicado en 1999

Stem cell powwow in Squaw Valley.

artículo científico

Structure of the mouse leukaemia inhibitory factor receptor gene: regulated expression of mRNA encoding a soluble receptor isoform from an alternative 5' untranslated region.

artículo científico publicado en 1997

The X-inactivation trans-activator Rnf12 is negatively regulated by pluripotency factors in embryonic stem cells.

artículo científico publicado en 2011

The developmental dismantling of pluripotency is reversed by ectopic Oct4 expression ⬇️

artículo científico publicado el 1 de julio de 2012

The evolving biology of cell reprogramming.

artículo científico publicado en 2011

The homeodomain protein Nanog and pluripotency in mouse embryonic stem cells

artículo científico publicado en 2005

The pluripotency factor Nanog regulates pericentromeric heterochromatin organization in mouse embryonic stem cells

artículo científico publicado en 2016

The pluripotency rheostat Nanog functions as a dimer

artículo científico publicado en 2008

The pluripotent genome in three dimensions is shaped around pluripotency factors

artículo científico publicado en 2013

Transcription factor heterogeneity and epiblast pluripotency.

artículo científico publicado en 2011

Transcriptional up-regulation of the mouse cytosolic glutathione peroxidase gene in erythroid cells is due to a tissue-specific 3' enhancer containing functionally important CACC/GT motifs and binding sites for GATA and Ets transcription factors.

artículo científico publicado en 1993

Lista de obras de Ian Chambers

A direct physical interaction between Nanog and Sox2 regulates embryonic stem cell self-renewal

A distinct expression pattern in mammalian testes indicates a conserved role for NANOG in spermatogenesis.

A new twist to Sin3 complexes in pluripotent cells

An Oct4-centered protein interaction network in embryonic stem cells

BMP induction of Id proteins suppresses differentiation and sustains embryonic stem cell self-renewal in collaboration with STAT3

Characterization of the uterine phenotype during the peri-implantation period for LIF-null, MF1 strain mice.

Complementary tissue-specific expression of LIF and LIF-receptor mRNAs in early mouse embryogenesis

Derivation of germline competent embryonic stem cells with a combination of interleukin-6 and soluble interleukin-6 receptor

Dicistronic targeting constructs: reporters and modifiers of mammalian gene expression.

Distinct Contributions of Tryptophan Residues within the Dimerization Domain to Nanog Function

Distinct Signaling Requirements for the Establishment of ESC Pluripotency in Late-Stage EpiSCs

Distinct SoxB1 networks are required for naïve and primed pluripotency

Dynamic changes in Sox2 spatio-temporal expression promote the second cell fate decision through Fgf4/Fgfr2 signalling in preimplantation mouse embryos

Effect of selenium status on mRNA levels for glutathione peroxidase in rat liver

Endogenous epitope-tagging of Tet1, Tet2 and Tet3 identifies TET2 as a naïve pluripotency marker

Engineering the mouse genome with bacterial artificial chromosomes to create multipurpose alleles.

Esrrb Complementation Rescues Development of Nanog-Null Germ Cells

Esrrb extinction triggers dismantling of naïve pluripotency and marks commitment to differentiation

Estrogen-related receptor beta interacts with Oct4 to positively regulate Nanog gene expression

Expression of alternative forms of differentiation inhibiting activity (DIA/LIF) during murine embryogenesis and in neonatal and adult tissues.

Expression-independent gene trap vectors for random and targeted mutagenesis in embryonic stem cells ⬇️

Formation of pluripotent stem cells in the mammalian embryo depends on the POU transcription factor Oct4

Functional Antagonism between OTX2 and NANOG Specifies a Spectrum of Heterogeneous Identities in Embryonic Stem Cells

Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells

Functional expression cloning of Nanog, a pluripotency sustaining factor in embryonic stem cells

Functional gene screening in embryonic stem cells implicates Wnt antagonism in neural differentiation

Hes1 desynchronizes differentiation of pluripotent cells by modulating STAT3 activity ⬇️

Lessons in learning: An effective process for engaging 12- to 14-year-olds in stem cell biology

Maintenance of the pluripotential phenotype of embryonic stem cells through direct activation of gp130 signalling pathways

Molecular coupling of Xist regulation and pluripotency.

Nanog is the gateway to the pluripotent ground state.

Nanog promotes transfer of pluripotency after cell fusion

Nanog retrotransposed genes with functionally conserved open reading frames.

Nanog safeguards pluripotency and mediates germline development

OCT4/SOX2-independent Nanog autorepression modulates heterogeneous Nanog gene expression in mouse ES cells.

Phenotypic complementation establishes requirements for specific POU domain and generic transactivation function of Oct-3/4 in embryonic stem cells.

Quantification of Pluripotency Transcription Factor Levels in Embryonic Stem Cells by Flow Cytometry ⬇️

Reduced Oct4 expression directs a robust pluripotent state with distinct signaling activity and increased enhancer occupancy by Oct4 and Nanog

Reprogramming Roadblocks Are System Dependent

Segregation of the mouse germline and soma

Selective influence of Sox2 on POU transcription factor binding in embryonic and neural stem cells.

Self-renewal of pluripotent embryonic stem cells is mediated via activation of STAT3

Self-renewal of teratocarcinoma and embryonic stem cells.

Signaling mechanisms regulating self-renewal and differentiation of pluripotent embryonic stem cells.

Stem cell powwow in Squaw Valley.

Structure of the mouse leukaemia inhibitory factor receptor gene: regulated expression of mRNA encoding a soluble receptor isoform from an alternative 5' untranslated region.

The X-inactivation trans-activator Rnf12 is negatively regulated by pluripotency factors in embryonic stem cells.

The developmental dismantling of pluripotency is reversed by ectopic Oct4 expression ⬇️

The evolving biology of cell reprogramming.

The homeodomain protein Nanog and pluripotency in mouse embryonic stem cells

The pluripotency factor Nanog regulates pericentromeric heterochromatin organization in mouse embryonic stem cells

The pluripotency rheostat Nanog functions as a dimer

The pluripotent genome in three dimensions is shaped around pluripotency factors

Transcription factor heterogeneity and epiblast pluripotency.

Transcriptional up-regulation of the mouse cytosolic glutathione peroxidase gene in erythroid cells is due to a tissue-specific 3' enhancer containing functionally important CACC/GT motifs and binding sites for GATA and Ets transcription factors.