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An optimised Cu(0)-RDRP approach for the synthesis of lipidated oligomeric vinyl azlactone: toward a versatile antimicrobial materials screening platform

artículo científico publicado en 2019

Evidence that cell surface localization of serine protease activity facilitates cleavage of the protease activated receptor CDCP1.

artículo científico publicado en 2017

Identification, Synthesis, and Biological Evaluation of the Major Human Metabolite of NLRP3 Inflammasome Inhibitor MCC950.

artículo científico publicado en 2016

In vitro evidence that KLK14 regulates the components of the HGF/Met axis, pro-HGF and HGF-activator inhibitor 1A and 1B.

artículo científico publicado en 2016

Prostatic trypsin-like kallikrein-related peptidases (KLKs) and other prostate-expressed tryptic proteinases as regulators of signalling via proteinase-activated receptors (PARs).

artículo científico publicado en 2008

Proteolysis-induced N-terminal ectodomain shedding of the integral membrane glycoprotein CUB domain-containing protein 1 (CDCP1) is accompanied by tyrosine phosphorylation of its C-terminal domain and recruitment of Src and PKCdelta.

artículo científico publicado en 2010

Selective cleavage of human sex hormone-binding globulin by kallikrein-related peptidases and effects on androgen action in LNCaP prostate cancer cells

artículo científico publicado en 2012

Substrate-guided design of a potent and selective kallikrein-related peptidase inhibitor for kallikrein 4.

artículo científico publicado en 2009

Sulfonylureas as Concomitant Insulin Secretagogues and NLRP3 Inflammasome Inhibitors.

artículo científico publicado en 2017

Synthesis of deuterium-labelled analogues of NLRP3 inflammasome inhibitor MCC950.

artículo científico publicado en 2017

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