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"End-stage" neurofibrillary tangle pathology in preclinical Alzheimer's disease: fact or fiction?

artículo científico publicado en 2011

"New Old Pathologies": AD, PART, and Cerebral Age-Related TDP-43 With Sclerosis (CARTS).

artículo científico publicado en 2016

A Comprehensive Behavioral Test Battery to Assess Learning and Memory in 129S6/Tg2576 Mice

artículo científico publicado en 2016

A Novel Plasma Based Biomarker of Alzheimer's Disease

artículo científico publicado en 2015

A cognitive electrophysiological signature differentiates amnestic mild cognitive impairment from normal aging

scientific article published on 19 January 2017

A comparison of time-homogeneous Markov chain and Markov process multi-state models

A computer-based approach to preventing pregnancy, STD, and HIV in rural adolescents

scientific article published on 01 January 2007

A novel method for the rapid detection of post-translationally modified visinin-like protein 1 in rat models of brain injury

artículo científico publicado en 2017

A randomized controlled Alzheimer's disease prevention trial's evolution into an exposure trial: the PREADViSE Trial

artículo científico publicado en 2013

ABCC9 gene polymorphism is associated with hippocampal sclerosis of aging pathology

artículo científico publicado en 2014

Acetylcholinesterase inhibitor treatment is associated with relatively slow cognitive decline in patients with Alzheimer's disease and AD + DLB

artículo científico publicado en 2009

Adjusting for mortality when identifying risk factors for transitions to mild cognitive impairment and dementia

artículo científico publicado en 2013

Age-expanded normative data for the Ruff 2&7 Selective Attention Test: evaluating cognition in older males

artículo científico publicado en 2012

Altered cargo proteins of human plasma endothelial cell-derived exosomes in atherosclerotic cerebrovascular disease.

artículo científico publicado en 2017

Altered lysosomal proteins in neural-derived plasma exosomes in preclinical Alzheimer disease

artículo científico publicado en 2015

Alzheimer Disease Pathology-Associated Polymorphism in a Complex Variable Number of Tandem Repeat Region Within the MUC6 Gene, Near the AP2A2 Gene

artículo científico publicado en 2020

Alzheimer's Biomarkers are Correlated with Brain Connectivity in Older Adults Differentially during Resting and Task States.

artículo científico publicado en 2016

Alzheimer's disease is not "brain aging": neuropathological, genetic, and epidemiological human studies

artículo científico publicado en 2011

Alzheimer's-type neuropathology in the precuneus is not increased relative to other areas of neocortex across a range of cognitive impairment

artículo científico publicado en 2008

Amyloid deposits in the banks (of the superior temporal sulcus) yield a high return about memory futures

scientific article published on 18 March 2020

Are Markov and semi-Markov models flexible enough for cognitive panel data?

artículo científico publicado en 2013

Arteriolosclerosis that affects multiple brain regions is linked to hippocampal sclerosis of ageing

artículo científico publicado en 2013

Assessing the discriminant ability, reliability, and comparability of multiple short forms of the Boston Naming Test in an Alzheimer's disease center cohort

artículo científico publicado en 2015

Association between male gender and cortical Lewy body pathology in large autopsy series

artículo científico publicado en 2010

Association of Antioxidant Supplement Use and Dementia in the Prevention of Alzheimer's Disease by Vitamin E and Selenium Trial (PREADViSE).

artículo científico publicado en 2017

Attention-deficit/hyperactivity disorder in childhood is associated with cognitive test profiles in the geriatric population but not with mild cognitive impairment or Alzheimer's disease

artículo científico publicado en 2011

Author Correction: Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

scientific article published on 01 September 2019

Author Response

artículo científico publicado en 2015

Aβ vaccination in combination with behavioral enrichment in aged beagles: effects on cognition, Aβ, and microhemorrhages

artículo científico publicado en 2016

Baseline subjective memory complaints associate with increased risk of incident dementia: the PREADVISE trial

artículo científico publicado en 2015

Behaviors Characteristic of Autism Spectrum Disorder in a Geriatric Cohort With Mild Cognitive Impairment or Early Dementia

artículo científico publicado en 2020

Bladder antimuscarinics and cognitive decline in elderly patients

artículo científico

Blood Flow Deficits and Cerebrovascular Changes in a Dietary Model of Hyperhomocysteinemia

scientific article published on 01 January 2019

Brain arteriolosclerosis

artículo científico publicado en 2020

Brain pathologies in extreme old age.

artículo científico publicado en 2015

Brain structure changes over time in normal and mildly impaired aged persons

artículo científico publicado en 2020

Brains with medial temporal lobe neurofibrillary tangles but no neuritic amyloid plaques are a diagnostic dilemma but may have pathogenetic aspects distinct from Alzheimer disease.

artículo científico publicado en 2009

CERAD practice effects and attrition bias in a dementia prevention trial

artículo científico publicado en 2013

COVID-19 and geriatric clinical trials research

scientific article published on 16 September 2020

COVID-19 and the neurological disease therapeutic pipeline

scientific article published on 18 December 2020

Calcium Channel Blockers, Progression to Dementia, and Effects on Amyloid Beta Peptide Production

artículo científico publicado en 2015

Cancer history associates with a lower burden of dementia and Alzheimer’s‐type neuropathology in autopsied research volunteers

scientific article published in 2021

Challenges and Considerations Related to Studying Dementia in Blacks/African Americans

artículo científico

Clinicopathologic correlations in a large Alzheimer disease center autopsy cohort: neuritic plaques and neurofibrillary tangles "do count" when staging disease severity

artículo científico publicado en 2007

Comparison of behaviors characteristic of autism spectrum disorder behaviors and behavioral and psychiatric symptoms of dementia

artículo científico publicado en 2020

Declining levels of functionally specialized synaptic proteins in plasma neuronal exosomes with progression of Alzheimer's disease

artículo científico publicado en 2017

Decreased synaptic proteins in neuronal exosomes of frontotemporal dementia and Alzheimer's disease

artículo científico publicado en 2016

Deficient neurotrophic factors of CSPG4-type neural cell exosomes in Alzheimer disease

artículo científico publicado en 2018

Dementia and "obesity paradox": is this for real or are we missing something? An epidemiologist's perspective

scholarly article by Daniela C Moga et al published 9 July 2014 in Journal of the American Medical Directors Association

Determining the role of IL-4 induced neuroinflammation in microglial activity and amyloid-β using BV2 microglial cells and APP/PS1 transgenic mice

artículo científico publicado en 2015

Diabetes is associated with cerebrovascular but not Alzheimer's disease neuropathology

artículo científico publicado en 2016

Diagnostic accuracy and practice effects in the National Alzheimer's Coordinating Center Uniform Data Set neuropsychological battery

artículo científico publicado en 2014

Differential reports of pain and depression differentiate mild cognitive impairment from cognitively intact elderly participants

artículo científico publicado en 2012

Diffuse Amyloid-β Plaques, Neurofibrillary Tangles, and the Impact of APOE in Elderly Persons' Brains Lacking Neuritic Amyloid Plaques

artículo científico publicado en 2018

Disease-related microglia heterogeneity in the hippocampus of Alzheimer's disease, dementia with Lewy bodies, and hippocampal sclerosis of aging

artículo científico publicado en 2015

Distinct White Matter Changes Associated with Cerebrospinal Fluid Amyloid-β1 - 42 and Hypertension

artículo científico publicado en 2018

Distinct clinicopathologic clusters of persons with TDP-43 proteinopathy

artículo científico publicado en 2020

Down syndrome individuals with Alzheimer's disease have a distinct neuroinflammatory phenotype compared to sporadic Alzheimer's disease

artículo científico publicado en 2015

Dysfunctionally phosphorylated type 1 insulin receptor substrate in neural-derived blood exosomes of preclinical Alzheimer's disease

artículo científico publicado en 2014

Effect of Thiamine Administration on Lactate Clearance and Mortality in Patients With Septic Shock

scientific article published on 01 November 2018

Endothelial-derived plasma exosome proteins in Alzheimer's disease angiopathy

scientific article published on 10 March 2020

Estimation of Multi-state Models with Missing Covariate Values Based on Observed Data Likelihood

artículo científico publicado en 2018

Evaluating trajectories of episodic memory in normal cognition and mild cognitive impairment: Results from ADNI

artículo científico publicado en 2019

Factors Associated with Unmet Needs among African-American Dementia Care Providers

artículo científico publicado en 2016

Farmer suicides among states reporting violent deaths, 2003-2017

artículo científico publicado en 2023

From behind the shadows: a profile of the sexual abuse of older men residing in nursing homes

scientific article published on 01 January 2007

Genetic Sample Provision Among National Alzheimer's Coordinating Center Participants

Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

artículo científico publicado en 2019

Genomics and CSF analyses implicate thyroid hormone in hippocampal sclerosis of aging

artículo científico publicado en 2016

Global Cerebral Atrophy Detected by Routine Imaging: Relationship with Age, Hippocampal Atrophy, and White Matter Hyperintensities.

artículo científico publicado en 2018

High complement levels in astrocyte-derived exosomes of Alzheimer's disease

artículo científico publicado en 2018

Hippocampal Sclerosis of Aging Can Be Segmental: Two Cases and Review of the Literature

artículo científico publicado en 2015

Hippocampal sclerosis in advanced age: clinical and pathological features.

artículo científico publicado en 2011

Hippocampal sclerosis of aging, a prevalent and high-morbidity brain disease

artículo científico publicado en 2013

Human cerebral neuropathology of Type 2 diabetes mellitus

artículo científico publicado en 2008

INtervention for Cognitive Reserve Enhancement in delaying the onset of Alzheimer's Symptomatic Expression (INCREASE), a randomized controlled trial: rationale, study design, and protocol

artículo científico publicado en 2019

Identification of preclinical Alzheimer's disease by a profile of pathogenic proteins in neurally derived blood exosomes: A case-control study

artículo científico publicado en 2014

Incentives and barriers to research participation and brain donation among African Americans

artículo científico publicado en 2013

Limbic-predominant age-related TDP-43 encephalopathy differs from frontotemporal lobar degeneration

scientific article published on 24 August 2020

Low neural exosomal levels of cellular survival factors in Alzheimer's disease

artículo científico publicado en 2015

Low sensitivity in clinical diagnoses of dementia with Lewy bodies

artículo científico publicado en 2009

Markov chains and semi-Markov models in time-to-event analysis

artículo científico publicado en 2013

Matrix Metalloproteinase-Mediated Blood-Brain Barrier Dysfunction in Epilepsy.

artículo científico publicado en 2018

Memory-Related Frontal Brainwaves Predict Transition to Mild Cognitive Impairment in Healthy Older Individuals Five Years Before Diagnosis

artículo científico publicado en 2020

Microbleeds and Cerebral Amyloid Angiopathy in the Brains of People with Down Syndrome with Alzheimer's Disease

scholarly article by Alex M Helman et al published 2019 in Journal of Alzheimer's Disease

Mild cognitive impairment: statistical models of transition using longitudinal clinical data

artículo científico publicado en 2012

Modeling the association between 43 different clinical and pathological variables and the severity of cognitive impairment in a large autopsy cohort of elderly persons

artículo científico publicado en 2008

Multi-state models and missing covariate data: Expectation-Maximization algorithm for likelihood estimation

artículo científico publicado en 2017

Multiregional analysis of global 5-methylcytosine and 5-hydroxymethylcytosine throughout the progression of Alzheimer's disease

artículo científico publicado en 2016

Musical Training and Late-Life Cognition.

artículo científico publicado en 2013

One-Year Evaluation of a Targeted Medication Therapy Management Intervention for Older Adults

artículo científico publicado en 2020

Optimizing medication appropriateness in older adults: a randomized clinical interventional trial to decrease anticholinergic burden.

artículo científico publicado en 2017

Outcomes after diagnosis of mild cognitive impairment in a large autopsy series

artículo científico publicado en 2017

Overlapping but distinct TDP-43 and tau pathologic patterns in aged hippocampi

artículo científico publicado en 2017

Patterns and predictors of chronic opioid use in older adults: A retrospective cohort study

artículo científico publicado en 2019

Plasma neuronal exosomal levels of Alzheimer's disease biomarkers in normal aging

artículo científico publicado en 2016

Post-acquisition processing confounds in brain volumetric quantification of white matter hyperintensities

artículo científico publicado en 2019

Practice effects in a longitudinal, multi-center Alzheimer's disease prevention clinical trial.

artículo científico publicado en 2012

Preclinical AD Workgroup staging: pathological correlates and potential challenges.

artículo científico publicado en 2011

Prediction of preclinical Alzheimer's disease: longitudinal rates of change in cognition

artículo científico publicado en 2011

Prevalence and Clinical Phenotype of Quadruple Misfolded Proteins in Older Adults

scientific article published on 22 June 2020

Preventing P-gp Ubiquitination Lowers Aβ Brain Levels in an Alzheimer's Disease Mouse Model.

artículo científico publicado en 2018

Primary age-related tauopathy (PART): a common pathology associated with human aging

artículo científico publicado en 2014

Public Understanding and Opinions regarding Genetic Research on Alzheimer's Disease

artículo científico publicado en 2018

Quality of education and memory test performance in older men: the New York University Paragraph Recall Test normative data

artículo científico publicado en 2013

Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

artículo científico publicado en 2017

Relationship of Type 2 Diabetes to Human Brain Pathology

artículo científico publicado en 2018

Relative preservation of MMSE scores in autopsy-proven dementia with Lewy bodies

artículo científico publicado en 2009

Risk factors and global cognitive status related to brain arteriolosclerosis in elderly individuals

artículo científico publicado en 2016

Risk of incident clinical diagnosis of Alzheimer's disease-type dementia attributable to pathology-confirmed vascular disease

artículo científico publicado en 2016

Rod-shaped microglia morphology is associated with aging in 2 human autopsy series

artículo científico publicado en 2017

Rural-Urban Differences in Alzheimer's Disease and Related Disorders Diagnostic Prevalence in Kentucky and West Virginia

scientific article published on 30 October 2015

Self-Reported Memory Complaints: A Comparison of Demented and Unimpaired Outcomes

artículo científico publicado en 2016

Self-Reported Sleep Apnea and Dementia Risk: Findings from the Prevention of Alzheimer's Disease with Vitamin E and Selenium Trial

artículo científico publicado en 2016

Self-reported head injury and risk of late-life impairment and AD pathology in an AD center cohort

artículo científico publicado en 2014

Self-reported memory complaints: implications from a longitudinal cohort with autopsies

artículo científico publicado en 2014

Serum antibodies to periodontal pathogens are a risk factor for Alzheimer's disease

artículo científico publicado en 2012

Sexual predators who target elders: findings from the first national study of sexual abuse in care facilities

artículo científico publicado en 2008

The Amygdala as a Locus of Pathologic Misfolding in Neurodegenerative Diseases

artículo científico publicado en 2017

The Effect of Vascular Neuropathology on Late-life Cognition: Results from the SMART Project

artículo científico publicado en 2016

The Sexual Victimization of Older Women Living in Nursing Homes

artículo científico publicado en 2015

The Statistical Modeling of Aging and Risk of Transition Project: Data Collection and Harmonization Across 11 Longitudinal Cohort Studies of Aging, Cognition, and Dementia

The effects of a computer-based pregnancy, STD, and HIV prevention intervention: a nine-school trial

artículo científico publicado en 2007

Tobacco Smoking and Dementia in a Kentucky Cohort: A Competing Risk Analysis

artículo científico publicado en 2019

Transition from an M1 to a mixed neuroinflammatory phenotype increases amyloid deposition in APP/PS1 transgenic mice

artículo científico publicado en 2014

University of Kentucky Sanders-Brown healthy brain aging volunteers: donor characteristics, procedures and neuropathology

artículo científico publicado en 2012

Victim, Allegation, and Investigation Characteristics Associated With Substantiated Reports of Sexual Abuse of Adults in Residential Care Settings.

artículo científico publicado en 2016

Visual Arts Education improves self-esteem for persons with dementia and reduces caregiver burden: A randomized controlled trial.

artículo científico publicado en 2018

Vitamin E and all-cause mortality: a meta-analysis

artículo científico publicado en 2011

White matter integrity is associated with cerebrospinal fluid markers of Alzheimer's disease in normal adults.

artículo científico publicado en 2014