Lista de obras - Waseem Qasim - Dominio Público Uruguay

"Darwinian" tumor-suppression model unsupported in clinical experience

artículo científico publicado en 2014

'Mini' U6 Pol III promoter exhibits nucleosome redundancy and supports multiplexed coupling of CRISPR/Cas9 effects

artículo científico publicado en 2020

22q11.2 Deletion Syndrome with Life-Threatening Adenovirus Infection

A double cure: Omenn syndrome and β thalassaemia successfully treated with mismatched unrelated donor transplantation

scientific article published on 23 May 2011

Abnormal expression of only the CD34 part of a transgenic CD34/herpes simplex virus-thymidine kinase fusion protein is associated with ganciclovir resistance

artículo científico publicado en 2008

Adoptive T-cell therapy for cancer in the United kingdom: a review of activity for the British Society of Gene and Cell Therapy annual meeting 2015.

artículo científico publicado en 2015

Allogeneic CAR T cell therapies for leukemia - R1

artículo científico publicado en 2019

Allogeneic hematopoietic stem-cell transplantation for leukocyte adhesion deficiency

artículo científico publicado en 2009

Alternative donor SCT for the treatment of MHC class II deficiency.

artículo científico publicado en 2012

Anticardiolipin antibodies and thromboembolism after BMT.

artículo científico publicado en 1998

Astrovirus VA1/HMO-C: an increasingly recognized neurotropic pathogen in immunocompromised patients

artículo científico publicado en 2015

Autologous Transplantation of Amniotic Fluid-Derived Mesenchymal Stem Cells into Sheep Fetuses

artículo científico publicado en 2016

Autologous transplantation of amniotic fluid-derived mesenchymal stem cells into sheep fetuses

artículo científico publicado en 2010

Automated manufacturing of chimeric antigen receptor T cells for adoptive immunotherapy using CliniMACS prodigy

artículo científico

Base-edited CAR T Cells for combinational therapy against T cell malignancies

Base-edited CAR T cells for combinational therapy against T cell malignancies

artículo científico publicado en 2021

Capture and generation of adenovirus specific T cells for adoptive immunotherapy

artículo científico publicado en 2006

Cell-specific and efficient expression in mouse and human B cells by a novel hybrid immunoglobulin promoter in a lentiviral vector.

artículo científico publicado en 2007

Clinical and immunologic outcome of patients with cartilage hair hypoplasia after hematopoietic stem cell transplantation.

artículo científico publicado en 2010

Clinical and immunological manifestations of patients with atypical severe combined immunodeficiency.

artículo científico publicado en 2011

Comparison of lentiviral and sleeping beauty mediated αβ T cell receptor gene transfer

artículo científico publicado en 2013

Cord blood T cells mediate enhanced antitumor effects compared with adult peripheral blood T cells.

artículo científico publicado en 2015

Cord blood transplantation recapitulates fetal ontogeny with a distinct molecular signature that supports CD4 T-cell reconstitution

scientific article published on 02 November 2017

Deep sequencing reveals persistence of cell-associated mumps vaccine virus in chronic encephalitis.

artículo científico publicado en 2016

Effect of stem cell source on long-term chimerism and event-free survival in children with primary immunodeficiency disorders after fludarabine and melphalan conditioning regimen

artículo científico publicado en 2016

Elimination of human leukemia cells in NOD/SCID mice by WT1-TCR gene-transduced human T cells

artículo científico publicado en 2005

Emerging applications of gene edited T cells for the treatment of leukemia

artículo científico publicado en 2017

Engineered T cell therapies

artículo científico publicado en 2015

Ex-vivo gene therapy restores LEKTI activity and corrects the architecture of Netherton syndrome-derived skin grafts

artículo científico publicado en 2010

FOXN1 forms higher-order nuclear condensates displaced by mutations causing immunodeficiency

artículo científico publicado en 2021

FOXRED1, encoding an FAD-dependent oxidoreductase complex-I-specific molecular chaperone, is mutated in infantile-onset mitochondrial encephalopathy

artículo científico publicado en 2010

FOXRED1, encoding an FAD-dependent oxidoreductase complex-I-specific molecular chaperone, is mutated in infantile-onset mitochondrial encephalopathy

artículo científico publicado en 2015

Frequent occurrence of cytomegalovirus retinitis during immune reconstitution warrants regular ophthalmic screening in high-risk pediatric allogeneic hematopoietic stem cell transplant recipients

artículo científico publicado en 2014

Gene Modified T Cell Therapies for Hematological Malignancies

artículo científico publicado en 2017

Gene therapies for inherited skin disorders

artículo científico publicado en 2014

Gene therapy for primary immunodeficiencies: current status and future prospects

artículo científico

Gene therapy for severe combined immune deficiency

artículo científico publicado en 2004

Gene therapy strategies to exploit TRIM derived restriction factors against HIV-1.

artículo científico publicado en 2014

Generation and Clinical Application of Gene-Modified Autologous Epidermal Sheets in Netherton Syndrome: Lessons Learned from a Phase 1 Trial

scientific article published on 05 August 2019

Genome-Edited T Cell Therapies.

artículo científico publicado en 2017

Hematopoietic stem cell transplantation for cytidine triphosphate synthase 1 (CTPS1) deficiency

artículo científico publicado en 2018

Hematopoietic stem cell transplantation in 29 patients hemizygous for hypomorphic IKBKG / NEMO mutations.

artículo científico publicado en 2017

Host natural killer immunity is a key indicator of permissiveness for donor cell engraftment in patients with severe combined immunodeficiency

artículo científico publicado en 2014

How I treat severe combined immunodeficiency

artículo científico publicado en 2013

Human Coronavirus OC43 Associated with Fatal Encephalitis

artículo científico publicado en 2016

Human Mesenchymal Stromal Cells Engineered to Express Collagen VII Can Restore Anchoring Fibrils in Recessive Dystrophic Epidermolysis Bullosa Skin Graft Chimeras

scientific article published on 19 July 2019

Human involucrin promoter mediates repression-resistant and compartment-specific LEKTI expression

artículo científico publicado en 2012

Hybrid lentiviral vectors

artículo científico publicado en 2010

Identifying functional defects in patients with immune dysregulation due to LRBA and CTLA-4 mutations.

artículo científico publicado en 2017

Immune reconstitution and recovery of FOXP3 (forkhead box P3)-expressing T cells after transplantation for IPEX (immune dysregulation, polyendocrinopathy, enteropathy, X-linked) syndrome

artículo científico publicado en 2008

Immune reconstitution following hematopoietic stem cell transplantation using different stem cell sources

scientific article published on 09 May 2019

Immunotherapy of HCC metastases with autologous T cell receptor redirected T cells, targeting HBsAg in a liver transplant patient

artículo científico publicado en 2014

Impact of viral reactivations in the era of pre-emptive antiviral drug therapy following allogeneic haematopoietic SCT in paediatric recipients ⬇️

artículo científico publicado el 26 de noviembre de 2012

Impaired EIF2S3 function associated with a novel phenotype of X-linked hypopituitarism with glucose dysregulation

scientific article published on 14 March 2019

Inherited GINS1 deficiency underlies growth retardation along with neutropenia and NK cell deficiency

artículo científico publicado en 2017

Interferon-γ capture T cell therapy for persistent Adenoviraemia following allogeneic haematopoietic stem cell transplantation

artículo científico publicado en 2013

Lentiviral Engineered Fibroblasts Expressing Codon-Optimized COL7A1 Restore Anchoring Fibrils in RDEB.

artículo científico publicado en 2016

Lentiviral gene therapy against human immunodeficiency virus type 1, using a novel human TRIM21-cyclophilin A restriction factor.

artículo científico publicado en 2012

Lentiviral vectors for T-cell suicide gene therapy: preservation of T-cell effector function after cytokine-mediated transduction

artículo científico publicado en 2007

Long Terminal Repeat CRISPR-CAR-Coupled "Universal" T Cells Mediate Potent Anti-leukemic Effects

artículo científico publicado en 2018

Long-term outcome and lineage-specific chimerism in 194 patients with Wiskott-Aldrich syndrome treated by hematopoietic cell transplantation in the period 1980-2009: an international collaborative study

artículo científico publicado en 2011

Management of adenovirus in children after allogeneic hematopoietic stem cell transplantation

artículo científico publicado en 2013

Manufacture of GMP-compliant functional adenovirus-specific T-cell therapy for treatment of post-transplant infectious complications

artículo científico publicado en 2016

Molecular remission of infant B-ALL after infusion of universal TALEN gene-edited CAR T cells

artículo científico publicado en 2017

Multicenter phase 1/2 application of adenovirus-specific T cells in high-risk pediatric patients after allogeneic stem cell transplantation

artículo científico publicado en 2018

Mutations in linker for activation of T cells (LAT) lead to a novel form of severe combined immunodeficiency

artículo científico publicado en 2016

New graft manipulation strategies improve the outcome of mismatched stem cell transplantation in children with primary immunodeficiencies

artículo científico publicado en 2019

Non-posttransplant lymphoproliferative disorder malignancy after hematopoietic stem cell transplantation in patients with primary immunodeficiency: UK experience

artículo científico publicado en 2018

Novel lentiviral vectors with mutated reverse transcriptase for mRNA delivery of TALE nucleases

artículo científico publicado en 2014

Omission of in vivo T-cell depletion promotes rapid expansion of naïve CD4+ cord blood lymphocytes and restores adaptive immunity within 2 months after unrelated cord blood transplant

artículo científico

One hundred percent survival after transplantation of 34 patients with Wiskott-Aldrich syndrome over 20 years

scientific article published on 25 July 2018

Peanut allergy transferred by BMT

scientific article published on 28 April 2014

Phase I study protocol for ex vivo lentiviral gene therapy for the inherited skin disease, Netherton syndrome

artículo científico publicado en 2013

Phase I study protocol for ex-vivo lentiviral gene therapy for the inherited skin disease, Netherton Syndrome

artículo científico publicado en 2013

Production and first-in-man use of T cells engineered to express a HSVTK-CD34 sort-suicide gene

artículo científico publicado en 2013

Progress and prospects for engineered T cell therapies

artículo científico publicado en 2014

RISC control for gene therapy

artículo científico publicado en 2006

Reply to: "To target or not to target viral antigens in HBV related HCC?".

artículo científico publicado en 2015

Safety and early efficacy outcomes for lentiviral fibroblast gene therapy in recessive dystrophic epidermolysis bullosa

scientific article published on 06 June 2019

Signal transducer and activator of transcription 2 deficiency is a novel disorder of mitochondrial fission

scientific journal article

Sleeping beauty transposition from nonintegrating lentivirus

artículo científico publicado en 2009

Superantigen scalded skin syndromes

artículo científico publicado en 1998

T cell receptor-therapy in HBV-related hepatocellularcarcinoma

artículo científico publicado en 2015

T cell transduction and suicide with an enhanced mutant thymidine kinase.

artículo científico publicado en 2002

T-cell receptor αβ+ and CD19+ cell-depleted haploidentical and mismatched hematopoietic stem cell transplantation in primary immune deficiency.

artículo científico publicado en 2017

TCRαβ/CD3 disruption enables CD3-specific antileukemic T cell immunotherapy

The impact of retroviral suicide gene transduction procedures on T cells

artículo científico publicado en 2003

Third-party virus-specific T cells eradicate adenoviraemia but trigger bystander graft-versus-host disease

artículo científico publicado en 2011

Treosulfan and Fludarabine Conditioning for Hematopoietic Stem Cell Transplantation in Children with Primary Immunodeficiency: UK Experience.

artículo científico publicado en 2017

Treosulfan-based conditioning regimens for hematopoietic stem cell transplantation in children with primary immunodeficiency: United Kingdom experience

scholarly article by Mary A Slatter published in April 2011

Umbilical cord blood transplantation without in vivo T-cell depletion for children with MHC class II deficiency

artículo científico publicado en 2018

Update on clinical gene therapy in childhood

artículo científico publicado en 2007

Variable phenotype of severe immunodeficiencies associated with RMRP gene mutations

artículo científico publicado en 2015

Lista de obras de Waseem Qasim

"Darwinian" tumor-suppression model unsupported in clinical experience

'Mini' U6 Pol III promoter exhibits nucleosome redundancy and supports multiplexed coupling of CRISPR/Cas9 effects

22q11.2 Deletion Syndrome with Life-Threatening Adenovirus Infection

A double cure: Omenn syndrome and β thalassaemia successfully treated with mismatched unrelated donor transplantation

Abnormal expression of only the CD34 part of a transgenic CD34/herpes simplex virus-thymidine kinase fusion protein is associated with ganciclovir resistance

Adoptive T-cell therapy for cancer in the United kingdom: a review of activity for the British Society of Gene and Cell Therapy annual meeting 2015.

Allogeneic CAR T cell therapies for leukemia - R1

Allogeneic hematopoietic stem-cell transplantation for leukocyte adhesion deficiency

Alternative donor SCT for the treatment of MHC class II deficiency.

Anticardiolipin antibodies and thromboembolism after BMT.

Astrovirus VA1/HMO-C: an increasingly recognized neurotropic pathogen in immunocompromised patients

Autologous Transplantation of Amniotic Fluid-Derived Mesenchymal Stem Cells into Sheep Fetuses

Autologous transplantation of amniotic fluid-derived mesenchymal stem cells into sheep fetuses

Automated manufacturing of chimeric antigen receptor T cells for adoptive immunotherapy using CliniMACS prodigy

Base-edited CAR T Cells for combinational therapy against T cell malignancies

Base-edited CAR T cells for combinational therapy against T cell malignancies

Capture and generation of adenovirus specific T cells for adoptive immunotherapy

Cell-specific and efficient expression in mouse and human B cells by a novel hybrid immunoglobulin promoter in a lentiviral vector.

Clinical and immunologic outcome of patients with cartilage hair hypoplasia after hematopoietic stem cell transplantation.

Clinical and immunological manifestations of patients with atypical severe combined immunodeficiency.

Comparison of lentiviral and sleeping beauty mediated αβ T cell receptor gene transfer

Cord blood T cells mediate enhanced antitumor effects compared with adult peripheral blood T cells.

Cord blood transplantation recapitulates fetal ontogeny with a distinct molecular signature that supports CD4 T-cell reconstitution

Deep sequencing reveals persistence of cell-associated mumps vaccine virus in chronic encephalitis.

Effect of stem cell source on long-term chimerism and event-free survival in children with primary immunodeficiency disorders after fludarabine and melphalan conditioning regimen

Elimination of human leukemia cells in NOD/SCID mice by WT1-TCR gene-transduced human T cells

Emerging applications of gene edited T cells for the treatment of leukemia

Engineered T cell therapies

Ex-vivo gene therapy restores LEKTI activity and corrects the architecture of Netherton syndrome-derived skin grafts

FOXN1 forms higher-order nuclear condensates displaced by mutations causing immunodeficiency

FOXRED1, encoding an FAD-dependent oxidoreductase complex-I-specific molecular chaperone, is mutated in infantile-onset mitochondrial encephalopathy

FOXRED1, encoding an FAD-dependent oxidoreductase complex-I-specific molecular chaperone, is mutated in infantile-onset mitochondrial encephalopathy

Frequent occurrence of cytomegalovirus retinitis during immune reconstitution warrants regular ophthalmic screening in high-risk pediatric allogeneic hematopoietic stem cell transplant recipients

Gene Modified T Cell Therapies for Hematological Malignancies

Gene therapies for inherited skin disorders

Gene therapy for primary immunodeficiencies: current status and future prospects

Gene therapy for severe combined immune deficiency

Gene therapy strategies to exploit TRIM derived restriction factors against HIV-1.

Generation and Clinical Application of Gene-Modified Autologous Epidermal Sheets in Netherton Syndrome: Lessons Learned from a Phase 1 Trial

Genome-Edited T Cell Therapies.

Hematopoietic stem cell transplantation for cytidine triphosphate synthase 1 (CTPS1) deficiency

Hematopoietic stem cell transplantation in 29 patients hemizygous for hypomorphic IKBKG / NEMO mutations.

Host natural killer immunity is a key indicator of permissiveness for donor cell engraftment in patients with severe combined immunodeficiency

How I treat severe combined immunodeficiency

Human Coronavirus OC43 Associated with Fatal Encephalitis

Human Mesenchymal Stromal Cells Engineered to Express Collagen VII Can Restore Anchoring Fibrils in Recessive Dystrophic Epidermolysis Bullosa Skin Graft Chimeras

Human involucrin promoter mediates repression-resistant and compartment-specific LEKTI expression

Hybrid lentiviral vectors

Identifying functional defects in patients with immune dysregulation due to LRBA and CTLA-4 mutations.

Immune reconstitution and recovery of FOXP3 (forkhead box P3)-expressing T cells after transplantation for IPEX (immune dysregulation, polyendocrinopathy, enteropathy, X-linked) syndrome

Immune reconstitution following hematopoietic stem cell transplantation using different stem cell sources

Immunotherapy of HCC metastases with autologous T cell receptor redirected T cells, targeting HBsAg in a liver transplant patient

Impact of viral reactivations in the era of pre-emptive antiviral drug therapy following allogeneic haematopoietic SCT in paediatric recipients ⬇️

Impaired EIF2S3 function associated with a novel phenotype of X-linked hypopituitarism with glucose dysregulation

Inherited GINS1 deficiency underlies growth retardation along with neutropenia and NK cell deficiency

Interferon-γ capture T cell therapy for persistent Adenoviraemia following allogeneic haematopoietic stem cell transplantation

Lentiviral Engineered Fibroblasts Expressing Codon-Optimized COL7A1 Restore Anchoring Fibrils in RDEB.

Lentiviral gene therapy against human immunodeficiency virus type 1, using a novel human TRIM21-cyclophilin A restriction factor.

Lentiviral vectors for T-cell suicide gene therapy: preservation of T-cell effector function after cytokine-mediated transduction

Long Terminal Repeat CRISPR-CAR-Coupled "Universal" T Cells Mediate Potent Anti-leukemic Effects

Long-term outcome and lineage-specific chimerism in 194 patients with Wiskott-Aldrich syndrome treated by hematopoietic cell transplantation in the period 1980-2009: an international collaborative study

Management of adenovirus in children after allogeneic hematopoietic stem cell transplantation

Manufacture of GMP-compliant functional adenovirus-specific T-cell therapy for treatment of post-transplant infectious complications

Molecular remission of infant B-ALL after infusion of universal TALEN gene-edited CAR T cells

Multicenter phase 1/2 application of adenovirus-specific T cells in high-risk pediatric patients after allogeneic stem cell transplantation

Mutations in linker for activation of T cells (LAT) lead to a novel form of severe combined immunodeficiency

New graft manipulation strategies improve the outcome of mismatched stem cell transplantation in children with primary immunodeficiencies

Non-posttransplant lymphoproliferative disorder malignancy after hematopoietic stem cell transplantation in patients with primary immunodeficiency: UK experience

Novel lentiviral vectors with mutated reverse transcriptase for mRNA delivery of TALE nucleases

Omission of in vivo T-cell depletion promotes rapid expansion of naïve CD4+ cord blood lymphocytes and restores adaptive immunity within 2 months after unrelated cord blood transplant

One hundred percent survival after transplantation of 34 patients with Wiskott-Aldrich syndrome over 20 years

Peanut allergy transferred by BMT

Phase I study protocol for ex vivo lentiviral gene therapy for the inherited skin disease, Netherton syndrome

Phase I study protocol for ex-vivo lentiviral gene therapy for the inherited skin disease, Netherton Syndrome

Production and first-in-man use of T cells engineered to express a HSVTK-CD34 sort-suicide gene

Progress and prospects for engineered T cell therapies

RISC control for gene therapy

Reply to: "To target or not to target viral antigens in HBV related HCC?".

Safety and early efficacy outcomes for lentiviral fibroblast gene therapy in recessive dystrophic epidermolysis bullosa