Lista de obras - Karim Boumediene - Dominio Público Uruguay

3-Deazaneplanocin A (DZNep), an inhibitor of the histone methyltransferase EZH2, induces apoptosis and reduces cell migration in chondrosarcoma cells

artículo científico publicado en 2014

Anti-inflammatory and chondroprotective effects of the S-adenosylhomocysteine hydrolase inhibitor 3-Deazaneplanocin A, in human articular chondrocytes.

artículo científico

Anti-inflammatory effects of an injectable copolymer of fatty acids (Ara 3000 beta®) in joint diseases.

artículo científico publicado en 2015

Antiproliferative effect of the histone demethylase inhibitor GSK-J4 in chondrosarcomas

artículo científico publicado en 2019

Asporin expression is highly regulated in human chondrocytes.

artículo científico publicado en 2011

Avocado/soya unsaponifiables enhance the expression of transforming growth factor beta1 and beta2 in cultured articular chondrocytes

artículo científico publicado en 1999

BMP-2, hypoxia, and COL1A1/HtrA1 siRNAs favor neo-cartilage hyaline matrix formation in chondrocytes

artículo científico publicado en 2014

Cell density-dependent proliferative effects of transforming growth factor (TGF)-beta 1, beta 2, and beta 3 in human chondrosarcoma cells HCS-2/8 are associated with changes in the expression of TGF-beta receptor type I.

artículo científico publicado en 2001

Cell-cycle-dependent expression of transforming growth factor beta type I receptor correlates with differential proliferative effects of TGFbeta1 in articular chondrocytes.

artículo científico publicado en 1998

Characterization of distinct mesenchymal-like cell populations from human skeletal muscle in situ and in vitro.

artículo científico publicado en 2010

Chondroitin sulphate decreases collagen synthesis in normal and scleroderma fibroblasts through a Smad-independent TGF-beta pathway--implication of C-Krox and Sp1.

artículo científico publicado en 2008

Comparative proteomic analysis of human mesenchymal and embryonic stem cells: towards the definition of a mesenchymal stem cell proteomic signature.

artículo científico publicado en 2009

Deciphering chondrocyte behaviour in matrix-induced autologous chondrocyte implantation to undergo accurate cartilage repair with hyaline matrix ⬇️

artículo científico publicado el 18 de abril de 2012

Decrease of cartilage transforming growth factor-beta receptor II expression in the rabbit experimental osteoarthritis--potential role in cartilage breakdown.

artículo científico publicado en 1998

Development of a simple osteoarthritis model useful to predict in vitro the anti-hypertrophic action of drugs

artículo científico publicado en 2019

Different phosphorylated forms of inositolphosphate glycan could be involved in the transforming growth factor-gb 1 (TGF-β1) signalling pathway

artículo científico publicado en 1994

Differential effects of hyaluronan and its fragments on fibroblasts: relation to wound healing.

artículo científico publicado en 2008

Differentiation potential of human muscle-derived cells towards chondrogenic phenotype in alginate beads culture.

artículo científico publicado en 2008

Effect of hypoxia and reoxygenation on gene expression and response to interleukin-1 in cultured articular chondrocytes.

artículo científico publicado en 2004

Effect of interleukin-1beta on transforming growth factor-beta and bone morphogenetic protein-2 expression in human periodontal ligament and alveolar bone cells in culture: modulation by avocado and soybean unsaponifiables.

artículo científico publicado en 2006

Enhanced hyaline cartilage matrix synthesis in collagen sponge scaffolds by using siRNA to stabilize chondrocytes phenotype cultured with bone morphogenetic protein-2 under hypoxia.

artículo científico publicado en 2013

Epigenetic dynamic during endochondral ossification and articular cartilage development

article

Evaluation of the impact of S-adenosylmethionine-dependent methyltransferase inhibitor, 3-deazaneplanocin A, on tissue injury and cognitive function in mice.

artículo científico publicado en 2018

Evaluation of ursolic acid isolated from Ilex paraguariensis and derivatives on aromatase inhibition

artículo científico publicado en 2008

Expression of TGF-betas and their receptors is differentially modulated by reactive oxygen species and nitric oxide in human articular chondrocytes.

artículo científico publicado en 2002

Flow cytometric detection of transforming growth factor-β expression in rabbit articular chondrocytes (RAC) in culture—Association with S-phase traverse

article

Genetic Determinism of Primary Early-Onset Osteoarthritis.

artículo científico

Histone methylases as novel drug targets: developing inhibitors of EZH2.

artículo científico publicado en 2014

Hypoxia inducible factor 1 alpha down-regulates type i collagen through Sp3 transcription factor in human chondrocytes

artículo científico publicado en 2016

Hypoxia-inducible factor 1alpha inhibits the fibroblast-like markers type I and type III collagen during hypoxia-induced chondrocyte redifferentiation: hypoxia not only induces type II collagen and aggrecan, but it also inhibits type I and type III

artículo científico publicado en 2009

Identification of an easy to use 3D culture model to investigate invasion and anticancer drug response in chondrosarcomas

artículo científico publicado en 2017

Immunohistochemical analysis of transforming growth factor beta isoforms and their receptors in human cartilage from normal and osteoarthritic femoral heads

artículo científico publicado en 2003

Interleukin-1beta impairment of transforming growth factor beta1 signaling by down-regulation of transforming growth factor beta receptor type II and up-regulation of Smad7 in human articular chondrocytes

artículo científico publicado en 2007

Interleukin-1beta up-regulation of Smad7 via NF-kappaB activation in human chondrocytes.

artículo científico publicado en 2008

Interleukin-6 (IL-6) and/or soluble IL-6 receptor down-regulation of human type II collagen gene expression in articular chondrocytes requires a decrease of Sp1.Sp3 ratio and of the binding activity of both factors to the COL2A1 promoter

artículo científico publicado en 2007

Mediation of interleukin-1beta-induced transforming growth factor beta1 expression by activator protein 4 transcription factor in primary cultures of bovine articular chondrocytes: possible cooperation with activator protein 1.

artículo científico publicado en 2003

Modulation of Skin Inflammatory Response by Active Components of Silymarin

artículo científico publicado en 2018

Modulation of transforming growth factor beta signalling pathway genes by transforming growth factor beta in human osteoarthritic chondrocytes: involvement of Sp1 in both early and late response cells to transforming growth factor beta ⬇️

artículo científico publicado el 15 de febrero de 2011

Molecular mechanism of hypoxia-induced chondrogenesis and its application in in vivo cartilage tissue engineering ⬇️

artículo científico publicado el 6 de junio de 2012

NF-κB accumulation associated with COL1A1 transactivators defects during chronological aging represses type I collagen expression through a -112/-61-bp region of the COL1A1 promoter in human skin fibroblasts

artículo científico publicado en 2012

NFkappaB mediates IL-1beta-induced down-regulation of TbetaRII through the modulation of Sp3 expression.

artículo científico publicado en 2007

Regulation and Role of TGFβ Signaling Pathway in Aging and Osteoarthritis Joints

artículo científico publicado en 2013

Regulatory mechanism of transforming growth factor beta receptor type II degradation by interleukin-1 in primary chondrocytes.

artículo científico publicado en 2012

Semiquantitative reverse transcription-polymerase chain reaction analysis of syndecan-1 and -4 messages in cartilage and cultured chondrocytes from osteoarthritic joints

artículo científico publicado en 2000

Sox9/Sox6 and Sp1 are involved in the insulin-like growth factor-I-mediated upregulation of human type II collagen gene expression in articular chondrocytes.

artículo científico publicado en 2012

Stimulating effect of diacerein on TGF-beta1 and beta2 expression in articular chondrocytes cultured with and without interleukin-1.

artículo científico publicado en 1999

TOL19-001 reduces inflammation and MMP expression in monolayer cultures of tendon cells

artículo científico publicado en 2015

The Antitumoral Effect of the S-Adenosylhomocysteine Hydrolase Inhibitor, 3-Deazaneplanocin A, is Independent of EZH2 but is Correlated with EGFR Downregulation in Chondrosarcomas

artículo científico publicado en 2019

The p65 subunit of NF-κB inhibits COL1A1 gene transcription in human dermal and scleroderma fibroblasts through its recruitment on promoter by protein interaction with transcriptional activators (c-Krox, Sp1, and Sp3).

artículo científico publicado en 2011

Type II TGFβ receptor modulates chondrocyte phenotype.

artículo científico publicado en 2012

Up-regulation of type II collagen gene by 17β-estradiol in articular chondrocytes involves Sp1/3, Sox-9, and estrogen receptor α.

artículo científico publicado en 2014

Use of Adult Stem Cells for Cartilage Tissue Engineering: Current Status and Future Developments

artículo científico publicado en 2015

Lista de obras de Karim Boumediene

3-Deazaneplanocin A (DZNep), an inhibitor of the histone methyltransferase EZH2, induces apoptosis and reduces cell migration in chondrosarcoma cells

Anti-inflammatory and chondroprotective effects of the S-adenosylhomocysteine hydrolase inhibitor 3-Deazaneplanocin A, in human articular chondrocytes.

Anti-inflammatory effects of an injectable copolymer of fatty acids (Ara 3000 beta®) in joint diseases.

Antiproliferative effect of the histone demethylase inhibitor GSK-J4 in chondrosarcomas

Asporin expression is highly regulated in human chondrocytes.

Avocado/soya unsaponifiables enhance the expression of transforming growth factor beta1 and beta2 in cultured articular chondrocytes

BMP-2, hypoxia, and COL1A1/HtrA1 siRNAs favor neo-cartilage hyaline matrix formation in chondrocytes

Cell density-dependent proliferative effects of transforming growth factor (TGF)-beta 1, beta 2, and beta 3 in human chondrosarcoma cells HCS-2/8 are associated with changes in the expression of TGF-beta receptor type I.

Cell-cycle-dependent expression of transforming growth factor beta type I receptor correlates with differential proliferative effects of TGFbeta1 in articular chondrocytes.

Characterization of distinct mesenchymal-like cell populations from human skeletal muscle in situ and in vitro.

Chondroitin sulphate decreases collagen synthesis in normal and scleroderma fibroblasts through a Smad-independent TGF-beta pathway--implication of C-Krox and Sp1.

Comparative proteomic analysis of human mesenchymal and embryonic stem cells: towards the definition of a mesenchymal stem cell proteomic signature.

Deciphering chondrocyte behaviour in matrix-induced autologous chondrocyte implantation to undergo accurate cartilage repair with hyaline matrix ⬇️

Decrease of cartilage transforming growth factor-beta receptor II expression in the rabbit experimental osteoarthritis--potential role in cartilage breakdown.

Development of a simple osteoarthritis model useful to predict in vitro the anti-hypertrophic action of drugs

Different phosphorylated forms of inositolphosphate glycan could be involved in the transforming growth factor-gb 1 (TGF-β1) signalling pathway

Differential effects of hyaluronan and its fragments on fibroblasts: relation to wound healing.

Differentiation potential of human muscle-derived cells towards chondrogenic phenotype in alginate beads culture.

Effect of hypoxia and reoxygenation on gene expression and response to interleukin-1 in cultured articular chondrocytes.

Effect of interleukin-1beta on transforming growth factor-beta and bone morphogenetic protein-2 expression in human periodontal ligament and alveolar bone cells in culture: modulation by avocado and soybean unsaponifiables.

Enhanced hyaline cartilage matrix synthesis in collagen sponge scaffolds by using siRNA to stabilize chondrocytes phenotype cultured with bone morphogenetic protein-2 under hypoxia.

Epigenetic dynamic during endochondral ossification and articular cartilage development

Evaluation of the impact of S-adenosylmethionine-dependent methyltransferase inhibitor, 3-deazaneplanocin A, on tissue injury and cognitive function in mice.

Evaluation of ursolic acid isolated from Ilex paraguariensis and derivatives on aromatase inhibition

Expression of TGF-betas and their receptors is differentially modulated by reactive oxygen species and nitric oxide in human articular chondrocytes.

Flow cytometric detection of transforming growth factor-β expression in rabbit articular chondrocytes (RAC) in culture—Association with S-phase traverse

Genetic Determinism of Primary Early-Onset Osteoarthritis.

Histone methylases as novel drug targets: developing inhibitors of EZH2.

Hypoxia inducible factor 1 alpha down-regulates type i collagen through Sp3 transcription factor in human chondrocytes

Hypoxia-inducible factor 1alpha inhibits the fibroblast-like markers type I and type III collagen during hypoxia-induced chondrocyte redifferentiation: hypoxia not only induces type II collagen and aggrecan, but it also inhibits type I and type III

Identification of an easy to use 3D culture model to investigate invasion and anticancer drug response in chondrosarcomas

Immunohistochemical analysis of transforming growth factor beta isoforms and their receptors in human cartilage from normal and osteoarthritic femoral heads

Interleukin-1beta impairment of transforming growth factor beta1 signaling by down-regulation of transforming growth factor beta receptor type II and up-regulation of Smad7 in human articular chondrocytes

Interleukin-1beta up-regulation of Smad7 via NF-kappaB activation in human chondrocytes.

Interleukin-6 (IL-6) and/or soluble IL-6 receptor down-regulation of human type II collagen gene expression in articular chondrocytes requires a decrease of Sp1.Sp3 ratio and of the binding activity of both factors to the COL2A1 promoter

Mediation of interleukin-1beta-induced transforming growth factor beta1 expression by activator protein 4 transcription factor in primary cultures of bovine articular chondrocytes: possible cooperation with activator protein 1.

Modulation of Skin Inflammatory Response by Active Components of Silymarin

Modulation of transforming growth factor beta signalling pathway genes by transforming growth factor beta in human osteoarthritic chondrocytes: involvement of Sp1 in both early and late response cells to transforming growth factor beta ⬇️

Molecular mechanism of hypoxia-induced chondrogenesis and its application in in vivo cartilage tissue engineering ⬇️

NF-κB accumulation associated with COL1A1 transactivators defects during chronological aging represses type I collagen expression through a -112/-61-bp region of the COL1A1 promoter in human skin fibroblasts

NFkappaB mediates IL-1beta-induced down-regulation of TbetaRII through the modulation of Sp3 expression.

Regulation and Role of TGFβ Signaling Pathway in Aging and Osteoarthritis Joints

Regulatory mechanism of transforming growth factor beta receptor type II degradation by interleukin-1 in primary chondrocytes.

Semiquantitative reverse transcription-polymerase chain reaction analysis of syndecan-1 and -4 messages in cartilage and cultured chondrocytes from osteoarthritic joints

Sox9/Sox6 and Sp1 are involved in the insulin-like growth factor-I-mediated upregulation of human type II collagen gene expression in articular chondrocytes.

Stimulating effect of diacerein on TGF-beta1 and beta2 expression in articular chondrocytes cultured with and without interleukin-1.

TOL19-001 reduces inflammation and MMP expression in monolayer cultures of tendon cells

The Antitumoral Effect of the S-Adenosylhomocysteine Hydrolase Inhibitor, 3-Deazaneplanocin A, is Independent of EZH2 but is Correlated with EGFR Downregulation in Chondrosarcomas

The p65 subunit of NF-κB inhibits COL1A1 gene transcription in human dermal and scleroderma fibroblasts through its recruitment on promoter by protein interaction with transcriptional activators (c-Krox, Sp1, and Sp3).

Type II TGFβ receptor modulates chondrocyte phenotype.

Up-regulation of type II collagen gene by 17β-estradiol in articular chondrocytes involves Sp1/3, Sox-9, and estrogen receptor α.

Use of Adult Stem Cells for Cartilage Tissue Engineering: Current Status and Future Developments