Lista de obras - Oscar Millet - Dominio Público Uruguay

15N relaxation NMR studies of prolyl oligopeptidase, an 80 kDa enzyme, reveal a pre-existing equilibrium between different conformational states

scientific article published on 08 November 2011

A Metabolomics Signature Linked To Liver Fibrosis In The Serum Of Transplanted Hepatitis C Patients

artículo científico publicado en 2017

A New Method for Measuring Diffusion Coefficients by 2D NMR using Accordion Spectroscopy

artículo científico publicado en 1998

A Three-protein Charge Zipper Stabilizes a Complex Modulating Bacterial Gene Silencing.

artículo científico publicado en 2015

A graphical method for the analysis of anisotropic rotational diffusion in proteins

artículo científico publicado en 2001

A new spin probe of protein dynamics: nitrogen relaxation in 15N-2H amide groups

artículo científico publicado en 2005

Abnormal concentration of porphyrins in serum from COVID-19 patients

artículo científico publicado en 2020

Active-Site-Directed Inhibitors of Prolyl Oligopeptidase Abolish Its Conformational Dynamics.

artículo científico publicado en 2016

An NMR experiment for the accurate measurement of heteronuclear spin-lock relaxation rates

artículo científico publicado en 2002

Backbone chemical shifts assignments of D-allose binding protein in the free form and in complex with D-allose.

artículo científico publicado en 2010

Bioengineered PBGD variant improves the therapeutic index of gene therapy vectors for acute intermittent porphyria

scientific article published on 01 November 2018

Carbohydrate affinity for the glucose-galactose binding protein is regulated by allosteric domain motions.

artículo científico publicado en 2012

Clicked bis-PEG-peptide conjugates for studying calmodulin-Kv7.2 channel binding

artículo científico publicado en 2014

Contribution of Shape and Charge to the Inhibition of a Family GH99 endo-α-1,2-Mannanase

artículo científico publicado en 2017

Cosolute modulation of protein oligomerization reactions in the homeostatic timescale

artículo científico publicado en 2021

De novo designed library of linear helical peptides: an exploratory tool in the discovery of protein-protein interaction modulators

artículo científico publicado en 2014

Depletion of mitochondrial methionine adenosyltransferase α1 triggers mitochondrial dysfunction in alcohol-associated liver disease

artículo científico publicado en 2022

Deuterium spin probes of side-chain dynamics in proteins. 1. Measurement of five relaxation rates per deuteron in (13)C-labeled and fractionally (2)H-enriched proteins in solution

artículo científico publicado en 2002

Deuterium spin probes of side-chain dynamics in proteins. 2. Spectral density mapping and identification of nanosecond time-scale side-chain motions

artículo científico publicado en 2002

Diagonal-free 3D/4D HN,HN-TROSY-NOESY-TROSY.

artículo científico publicado en 2010

Directional coupling of oligodendrocyte connexin-47 and astrocyte connexin-43 gap junctions

scientific article published on 25 August 2018

Dissecting the microscopic steps of the cyclophilin A enzymatic cycle on the biological HIV-1 capsid substrate by NMR

artículo científico publicado en 2010

Disulfide driven folding for a conditionally disordered protein.

artículo científico publicado en 2017

Effects of systematic prone positioning in hypoxemic acute respiratory failure: a randomized controlled trial.

artículo científico publicado en 2004

Fluorinated Carbohydrates as Lectin Ligands: Simultaneous Screening of a Monosaccharide Library and Chemical Mapping by <sup>19</sup>F NMR Spectroscopy

artículo científico publicado en 2020

From 1,4-Disaccharide to 1,3-Glycosyl Carbasugar: Synthesis of a Bespoke Inhibitor of Family GH99 Endo-α-mannosidase

artículo científico publicado en 2018

Halophilic Protein Adaptation Results from Synergistic Residue-Ion Interactions in the Folded and Unfolded States.

artículo científico publicado en 2015

Halophilic enzyme activation induced by salts.

artículo científico publicado en 2011

Hereditary tyrosinemia type I-associated mutations in fumarylacetoacetate hydrolase reduce the enzyme stability and increase its aggregation rate

artículo científico publicado en 2019

Hydration dynamics of a halophilic protein in folded and unfolded states.

artículo científico publicado en 2012

In Vitro Approach To Identify Key Amino Acids in Low Susceptibility of Rabbit Prion Protein to Misfolding

artículo científico publicado en 2017

Influence of the Hofmeister anions on protein stability as studied by thermal denaturation and chemical shift perturbation.

artículo científico publicado en 2007

Intracellular rescue of the uroporphyrinogen III synthase activity in enzymes carrying the hotspot mutation C73R.

artículo científico publicado en 2011

Intrinsic dynamics of an enzyme underlies catalysis

artículo científico publicado en 2005

LDL receptor/lipoprotein recognition: endosomal weakening of ApoB and ApoE binding to the convex face of the LR5 repeat

artículo científico publicado en 2014

Macromolecular Crowding Fails To Fold a Globular Protein in Cells ⬇️

artículo científico publicado el 10 de mayo de 2011

Metabolic Characterization of Advanced Liver Fibrosis in HCV Patients as Studied by Serum 1H-NMR Spectroscopy

artículo científico publicado en 2016

Metabolic landscape of the mouse liver by quantitative <sup>31</sup> P-NMR analysis of the phosphorome

artículo científico publicado en 2020

Missense UROS mutations causing congenital erythropoietic porphyria reduce UROS homeostasis that can be rescued by proteasome inhibition.

artículo científico publicado en 2017

Molecular Determinants of Chronic Liver Disease as Studied by NMR-Metabolomics

artículo científico publicado en 2017

Mutation of Ser-50 and Cys-66 in Snapin modulates protein structure and stability.

artículo científico publicado en 2012

NMR measurement of the off rate from the first calcium-binding site of the synaptotagmin I C2A domain

artículo científico publicado en 2002

On the Origin of the Thermostabilization of Proteins Induced by Sodium Phosphate

artículo científico publicado en 2005

Pivoting between calmodulin lobes triggered by calcium in the Kv7.2/calmodulin complex.

artículo científico publicado en 2014

Probing nucleotide-binding effects on backbone dynamics and folding of the nucleotide-binding domain of the sarcoplasmic/endoplasmic-reticulum Ca2+-ATPase.

artículo científico publicado en 2004

Protein Stabilization and the Hofmeister Effect: The Role of Hydrophobic Solvation

artículo científico publicado en 2009

Protein functional dynamics in multiple timescales as studied by NMR spectroscopy.

artículo científico publicado en 2013

Protein tyrosine phosphatase oligomerization studied by a combination of 15N NMR relaxation and 129Xe NMR. Effect of buffer containing arginine and glutamic acid.

artículo científico publicado en 2007

Repurposing ciclopirox as a pharmacological chaperone in a model of congenital erythropoietic porphyria

artículo científico publicado en 2018

Scientific Response to the Coronavirus Crisis in Spain: Collaboration and Multidisciplinarity

artículo científico publicado en 2020

Side chain to main chain hydrogen bonds stabilize a polyglutamine helix in a transcription factor

artículo científico publicado en 2019

Structural Basis for the Aminoacid Composition of Proteins from Halophilic Archea

artículo científico publicado en 2009

Structural and functional analyses of the interaction of archaeal RNA polymerase with DNA

artículo científico publicado en 2012

Structural basis and energy landscape for the Ca2+ gating and calmodulation of the Kv7.2 K+ channel

artículo científico publicado en 2018

Structural basis of pyrrole polymerization in human porphobilinogen deaminase

scholarly article by Paula Pluta published in September 2018

Structural, thermodynamic, and mechanistical studies in uroporphyrinogen III synthase: molecular basis of congenital erythropoietic porphyria.

scientific article published on January 2011

Synthesis of aryl 3-O-beta-cellobiosyl-beta-D-glucopyranosides for reactivity studies of 1,3-1,4-beta-glucanases

artículo científico publicado en 1998

Synthesis, dihydrofolate reductase inhibition, anti-proliferative testing, and saturation transfer difference ¹H-NMR study of some new 2-substituted-4,6-diaminopyrimidine derivatives

artículo científico publicado en 2012

The Effects of Mutations on Motions of Side-chains in Protein L Studied by 2H NMR Dynamics and Scalar Couplings

article

The energetic cost of domain reorientation in maltose-binding protein as studied by NMR and fluorescence spectroscopy

artículo científico publicado en 2003

The mitochondrial intermembrane space oxireductase Mia40 funnels the oxidative folding pathway of the cytochrome c oxidase assembly protein Cox19.

artículo científico

The use of dansyl-calmodulin to study interactions with channels and other proteins.

artículo científico publicado en 2013

Therapeutic potential of proteasome inhibitors in congenital erythropoietic porphyria.

artículo científico publicado en 2013

Thermodynamics of protein-cation interaction: Ca+2 and Mg+2 binding to the fifth binding module of the LDL receptor

artículo científico publicado en 2010

Transmembrane and Juxtamembrane Structure of αL Integrin in Bicelles

artículo científico publicado en 2013

Tuning intracellular homeostasis of human uroporphyrinogen III synthase by enzyme engineering at a single hotspot of congenital erythropoietic porphyria.

artículo científico publicado en 2014

Unraveling the Conformational Landscape of Ligand Binding to Glucose/Galactose-Binding Protein by Paramagnetic NMR and MD Simulations.

artículo científico publicado en 2016

Uroporphyrinogen III synthase mutations related to congenital erythropoietic porphyria identify a key helix for protein stability.

artículo científico publicado en 2009

Lista de obras de Oscar Millet

15N relaxation NMR studies of prolyl oligopeptidase, an 80 kDa enzyme, reveal a pre-existing equilibrium between different conformational states

A Metabolomics Signature Linked To Liver Fibrosis In The Serum Of Transplanted Hepatitis C Patients

A New Method for Measuring Diffusion Coefficients by 2D NMR using Accordion Spectroscopy

A Three-protein Charge Zipper Stabilizes a Complex Modulating Bacterial Gene Silencing.

A graphical method for the analysis of anisotropic rotational diffusion in proteins

A new spin probe of protein dynamics: nitrogen relaxation in 15N-2H amide groups

Abnormal concentration of porphyrins in serum from COVID-19 patients

Active-Site-Directed Inhibitors of Prolyl Oligopeptidase Abolish Its Conformational Dynamics.

An NMR experiment for the accurate measurement of heteronuclear spin-lock relaxation rates

Backbone chemical shifts assignments of D-allose binding protein in the free form and in complex with D-allose.

Bioengineered PBGD variant improves the therapeutic index of gene therapy vectors for acute intermittent porphyria

Carbohydrate affinity for the glucose-galactose binding protein is regulated by allosteric domain motions.

Clicked bis-PEG-peptide conjugates for studying calmodulin-Kv7.2 channel binding

Contribution of Shape and Charge to the Inhibition of a Family GH99 endo-α-1,2-Mannanase

Cosolute modulation of protein oligomerization reactions in the homeostatic timescale

De novo designed library of linear helical peptides: an exploratory tool in the discovery of protein-protein interaction modulators

Depletion of mitochondrial methionine adenosyltransferase α1 triggers mitochondrial dysfunction in alcohol-associated liver disease

Deuterium spin probes of side-chain dynamics in proteins. 1. Measurement of five relaxation rates per deuteron in (13)C-labeled and fractionally (2)H-enriched proteins in solution

Deuterium spin probes of side-chain dynamics in proteins. 2. Spectral density mapping and identification of nanosecond time-scale side-chain motions

Diagonal-free 3D/4D HN,HN-TROSY-NOESY-TROSY.

Directional coupling of oligodendrocyte connexin-47 and astrocyte connexin-43 gap junctions

Dissecting the microscopic steps of the cyclophilin A enzymatic cycle on the biological HIV-1 capsid substrate by NMR

Disulfide driven folding for a conditionally disordered protein.

Effects of systematic prone positioning in hypoxemic acute respiratory failure: a randomized controlled trial.

Fluorinated Carbohydrates as Lectin Ligands: Simultaneous Screening of a Monosaccharide Library and Chemical Mapping by <sup>19</sup>F NMR Spectroscopy

From 1,4-Disaccharide to 1,3-Glycosyl Carbasugar: Synthesis of a Bespoke Inhibitor of Family GH99 Endo-α-mannosidase

Halophilic Protein Adaptation Results from Synergistic Residue-Ion Interactions in the Folded and Unfolded States.

Halophilic enzyme activation induced by salts.

Hereditary tyrosinemia type I-associated mutations in fumarylacetoacetate hydrolase reduce the enzyme stability and increase its aggregation rate

Hydration dynamics of a halophilic protein in folded and unfolded states.

In Vitro Approach To Identify Key Amino Acids in Low Susceptibility of Rabbit Prion Protein to Misfolding

Influence of the Hofmeister anions on protein stability as studied by thermal denaturation and chemical shift perturbation.

Intracellular rescue of the uroporphyrinogen III synthase activity in enzymes carrying the hotspot mutation C73R.

Intrinsic dynamics of an enzyme underlies catalysis

LDL receptor/lipoprotein recognition: endosomal weakening of ApoB and ApoE binding to the convex face of the LR5 repeat

Macromolecular Crowding Fails To Fold a Globular Protein in Cells ⬇️

Metabolic Characterization of Advanced Liver Fibrosis in HCV Patients as Studied by Serum 1H-NMR Spectroscopy

Metabolic landscape of the mouse liver by quantitative <sup>31</sup> P-NMR analysis of the phosphorome

Missense UROS mutations causing congenital erythropoietic porphyria reduce UROS homeostasis that can be rescued by proteasome inhibition.

Molecular Determinants of Chronic Liver Disease as Studied by NMR-Metabolomics

Mutation of Ser-50 and Cys-66 in Snapin modulates protein structure and stability.

NMR measurement of the off rate from the first calcium-binding site of the synaptotagmin I C2A domain

On the Origin of the Thermostabilization of Proteins Induced by Sodium Phosphate

Pivoting between calmodulin lobes triggered by calcium in the Kv7.2/calmodulin complex.

Probing nucleotide-binding effects on backbone dynamics and folding of the nucleotide-binding domain of the sarcoplasmic/endoplasmic-reticulum Ca2+-ATPase.

Protein Stabilization and the Hofmeister Effect: The Role of Hydrophobic Solvation

Protein functional dynamics in multiple timescales as studied by NMR spectroscopy.

Protein tyrosine phosphatase oligomerization studied by a combination of 15N NMR relaxation and 129Xe NMR. Effect of buffer containing arginine and glutamic acid.

Repurposing ciclopirox as a pharmacological chaperone in a model of congenital erythropoietic porphyria

Scientific Response to the Coronavirus Crisis in Spain: Collaboration and Multidisciplinarity

Side chain to main chain hydrogen bonds stabilize a polyglutamine helix in a transcription factor

Structural Basis for the Aminoacid Composition of Proteins from Halophilic Archea

Structural and functional analyses of the interaction of archaeal RNA polymerase with DNA

Structural basis and energy landscape for the Ca2+ gating and calmodulation of the Kv7.2 K+ channel

Structural basis of pyrrole polymerization in human porphobilinogen deaminase

Structural, thermodynamic, and mechanistical studies in uroporphyrinogen III synthase: molecular basis of congenital erythropoietic porphyria.

Synthesis of aryl 3-O-beta-cellobiosyl-beta-D-glucopyranosides for reactivity studies of 1,3-1,4-beta-glucanases

Synthesis, dihydrofolate reductase inhibition, anti-proliferative testing, and saturation transfer difference ¹H-NMR study of some new 2-substituted-4,6-diaminopyrimidine derivatives

The Effects of Mutations on Motions of Side-chains in Protein L Studied by 2H NMR Dynamics and Scalar Couplings

The energetic cost of domain reorientation in maltose-binding protein as studied by NMR and fluorescence spectroscopy

The mitochondrial intermembrane space oxireductase Mia40 funnels the oxidative folding pathway of the cytochrome c oxidase assembly protein Cox19.

The use of dansyl-calmodulin to study interactions with channels and other proteins.

Therapeutic potential of proteasome inhibitors in congenital erythropoietic porphyria.

Thermodynamics of protein-cation interaction: Ca+2 and Mg+2 binding to the fifth binding module of the LDL receptor

Transmembrane and Juxtamembrane Structure of αL Integrin in Bicelles

Tuning intracellular homeostasis of human uroporphyrinogen III synthase by enzyme engineering at a single hotspot of congenital erythropoietic porphyria.

Unraveling the Conformational Landscape of Ligand Binding to Glucose/Galactose-Binding Protein by Paramagnetic NMR and MD Simulations.

Uroporphyrinogen III synthase mutations related to congenital erythropoietic porphyria identify a key helix for protein stability.