Lista de obras - Fabio Candotti - Dominio Público Uruguay

A model for reticular dysgenesis shows impaired sensory organ development and hair cell regeneration linked to cellular stress

scientific article published on 20 December 2019

Aberrant glycosylation of IgA in Wiskott-Aldrich syndrome and X-linked thrombocytopenia

artículo científico publicado en 2012

Actionable diagnosis of neuroleptospirosis by next-generation sequencing

artículo científico publicado en 2014

Adenosine Deaminase (ADA)-Deficient Severe Combined Immune Deficiency (SCID) in the US Immunodeficiency Network (USIDNet) Registry

scientific article published on 02 September 2020

Advances in the understanding of cytokine signal transduction: the role of Jaks and STATs in immunoregulation and the pathogenesis of immunodeficiency

artículo científico publicado el 1 de noviembre de 1997

Advances of gene therapy for primary immunodeficiencies

artículo científico publicado en 2016

Age-Dependent Defects of Regulatory B Cells in Wiskott-Aldrich Syndrome Gene Knockout Mice

artículo científico publicado en 2015

Altered BCR and TLR signals promote enhanced positive selection of autoreactive transitional B cells in Wiskott-Aldrich syndrome

artículo científico publicado en 2015

American Society of Gene Therapy (ASGT) ad hoc subcommittee on retroviral-mediated gene transfer to hematopoietic stem cells

artículo científico publicado en 2003

Analysis of T-cell repertoire diversity in Wiskott-Aldrich syndrome

artículo científico publicado en 2005

Assessment of Immature Platelet Fraction in the Diagnosis of Wiskott-Aldrich Syndrome

artículo científico publicado en 2015

Autoimmunity in Wiskott-Aldrich syndrome

artículo científico publicado en 2003

B cell-intrinsic deficiency of the Wiskott-Aldrich syndrome protein (WASp) causes severe abnormalities of the peripheral B-cell compartment in mice.

artículo científico publicado en 2012

Bovine apolipoprotein B-100 is a dominant immunogen in therapeutic cell populations cultured in fetal calf serum in mice and humans

artículo científico publicado en 2007

Broad spectrum of autoantibodies in patients with Wiskott-Aldrich syndrome and X-linked thrombocytopenia

artículo científico publicado en 2015

Busulfan Pharmacokinetics in ADA SCID Gene Therapy

scientific article published on 09 July 2020

Clinical Manifestations and Pathophysiological Mechanisms of the Wiskott-Aldrich Syndrome.

artículo científico publicado en 2017

Clinical efficacy of gene-modified stem cells in adenosine deaminase-deficient immunodeficiency

artículo científico publicado en 2017

Cytokines and their role in lymphoid development, differentiation and homeostasis

artículo científico publicado en 2002

Cytoreductive conditioning intensity predicts clonal diversity in ADA-SCID retroviral gene therapy patients

artículo científico publicado en 2017

Defective inhibition of B-cell proliferation by Wiskott-Aldrich syndrome protein-deficient regulatory T cells

artículo científico publicado en 2011

Development of IgA nephropathy-like glomerulonephritis associated with Wiskott–Aldrich syndrome protein deficiency ⬇️

artículo científico publicado el 19 de octubre de 2011

Differential contribution of Wiskott-Aldrich syndrome protein to selective advantage in T- and B-cell lineages

artículo científico publicado en 2003

Early-onset stroke and vasculopathy associated with mutations in ADA2

artículo científico publicado en 2014

Efficient methods for targeted mutagenesis in zebrafish using zinc-finger nucleases: data from targeting of nine genes using CompoZr or CoDA ZFNs

artículo científico publicado en 2013

Elevated IgE and atopy in patients treated for early-onset ADA-SCID.

artículo científico publicado en 2013

FOXP3+ Tregs require WASP to restrain Th2-mediated food allergy

artículo científico publicado en 2016

Foamy virus vector-mediated gene correction of a mouse model of Wiskott-Aldrich syndrome

artículo científico publicado en 2012

Gene therapy for adenosine deaminase-deficient severe combined immune deficiency: clinical comparison of retroviral vectors and treatment plans.

artículo científico publicado en 2012

Gene therapy in infants with severe combined immunodeficiency

artículo científico publicado en 2002

Gene therapy model of X-linked severe combined immunodeficiency using a modified foamy virus vector

artículo científico publicado en 2013

Gene therapy: X-SCID transgene leukaemogenicity

artículo científico publicado en 2006

Gene transfer into hematopoietic stem cells as treatment for primary immunodeficiency diseases

artículo científico publicado en 2014

High incidence of lymphomas in a subgroup of wiskott–aldrich syndrome patients ⬇️

artículo científico publicado el 1 de mayo de 2003

Human adenylate kinase 2 deficiency causes a profound hematopoietic defect associated with sensorineural deafness

artículo científico publicado en 2009

Improving cellular therapy for primary immune deficiency diseases: recognition, diagnosis, and management

artículo científico publicado en 2009

In vitro functional correction of Hermansky-Pudlak Syndrome type-1 by lentiviral-mediated gene transfer

artículo científico publicado en 2014

In vivo retroviral gene transfer by direct intrafemoral injection results in correction of the SCID phenotype in Jak3 knock-out animals ⬇️

artículo científico publicado el 10 de abril de 2003

Individualized iterative phenotyping for genome-wide analysis of loss-of-function mutations

artículo científico publicado en 2015

Jak3 and the pathogenesis of severe combined immunodeficiency

artículo científico publicado en 2004

Jak3, severe combined immunodeficiency, and a new class of immunosuppressive drugs.

artículo científico publicado en 2005

Molecular and phenotypic abnormalities of B lymphocytes in patients with Wiskott-Aldrich syndrome

artículo científico publicado en 2013

Molecular aspects of primary immunodeficiencies: lessons from cytokine and other signaling pathways.

artículo científico publicado en 2002

Multicentric dermatofibrosarcoma protuberans in patients with adenosine deaminase-deficient severe combined immune deficiency

artículo científico publicado en 2011

Multiple patients with revertant mosaicism in a single Wiskott-Aldrich syndrome family.

artículo científico publicado en 2004

Myeloid dysplasia and bone marrow hypocellularity in adenosine deaminase-deficient severe combined immune deficiency.

artículo científico publicado en 2011

N-WASP is required for B-cell-mediated autoimmunity in Wiskott-Aldrich syndrome.

artículo científico publicado en 2015

Nuclear role of WASp in gene transcription is uncoupled from its ARP2/3-dependent cytoplasmic role in actin polymerization.

artículo científico publicado en 2014

Nuclear role of WASp in the pathogenesis of dysregulated TH1 immunity in human Wiskott-Aldrich syndrome

artículo científico publicado en 2010

Peptide library-based evaluation of T-cell receptor breadth detects defects in global and regulatory activation in human immunologic diseases

artículo científico publicado en 2013

Persistence and expression of the adenosine deaminase gene for 12 years and immune reaction to gene transfer components: long-term results of the first clinical gene therapy trial.

artículo científico publicado en 2002

Platelets from WAS patients show an increased susceptibility to ex vivo phagocytosis

artículo científico publicado en 2012

Primary Immune Deficiency Treatment Consortium (PIDTC) report

artículo científico publicado en 2013

Prolonged pancytopenia in a gene therapy patient with ADA-deficient SCID and trisomy 8 mosaicism: a case report

artículo científico publicado en 2006

Reconstitution of lymphoid development and function in ZAP-70-deficient mice following gene transfer into bone marrow cells

artículo científico publicado en 2002

Reduced Number of Dense Bodies and Reduced Serotonin Content in Platelets of Patients with Wiskott-Aldrich Syndrome. ⬇️

artículo científico publicado en 2009

Reticular dysgenesis-associated AK2 protects hematopoietic stem and progenitor cell development from oxidative stress

artículo científico publicado en 2015

Retroviral Transfer of Acidα-Glucosidase cDNA to Enzyme-Deficient Myoblasts Results in Phenotypic Spread of the Genotypic Correction by Both Secretion and Fusion ⬇️

artículo científico publicado el 1 de septiembre de 1997

Retrovirus-mediated WASP gene transfer corrects Wiskott-Aldrich syndrome T-cell dysfunction

artículo científico publicado en 2002

Second-site mutation in the Wiskott-Aldrich syndrome (WAS) protein gene causes somatic mosaicism in two WAS siblings ⬇️

artículo científico publicado el 1 de mayo de 2003

Self-inactivating retroviral vector-mediated gene transfer induces oncogene activation and immortalization of primary murine bone marrow cells

artículo científico publicado en 2009

Somatic Mosaicism Caused by Monoallelic Reversion of a Mutation in T Cells of a Patient with ADA‐SCID and the Effects of Enzyme Replacement Therapy on the Revertant Phenotype ⬇️

artículo científico publicado el 1 de noviembre de 2011

Somatic mosaicism in the Wiskott-Aldrich syndrome: molecular and functional characterization of genotypic revertants

artículo científico publicado en 2010

Systemic autoimmunity and defective Fas ligand secretion in the absence of the Wiskott-Aldrich syndrome protein

artículo científico publicado en 2010

The altered landscape of the human skin microbiome in patients with primary immunodeficiencies

artículo científico publicado en 2013

Type I interferonopathies in pediatric rheumatology

artículo científico publicado en 2016

Lista de obras de Fabio Candotti

A model for reticular dysgenesis shows impaired sensory organ development and hair cell regeneration linked to cellular stress

Aberrant glycosylation of IgA in Wiskott-Aldrich syndrome and X-linked thrombocytopenia

Actionable diagnosis of neuroleptospirosis by next-generation sequencing

Adenosine Deaminase (ADA)-Deficient Severe Combined Immune Deficiency (SCID) in the US Immunodeficiency Network (USIDNet) Registry

Advances in the understanding of cytokine signal transduction: the role of Jaks and STATs in immunoregulation and the pathogenesis of immunodeficiency

Advances of gene therapy for primary immunodeficiencies

Age-Dependent Defects of Regulatory B Cells in Wiskott-Aldrich Syndrome Gene Knockout Mice

Altered BCR and TLR signals promote enhanced positive selection of autoreactive transitional B cells in Wiskott-Aldrich syndrome

American Society of Gene Therapy (ASGT) ad hoc subcommittee on retroviral-mediated gene transfer to hematopoietic stem cells

Analysis of T-cell repertoire diversity in Wiskott-Aldrich syndrome

Assessment of Immature Platelet Fraction in the Diagnosis of Wiskott-Aldrich Syndrome

Autoimmunity in Wiskott-Aldrich syndrome

B cell-intrinsic deficiency of the Wiskott-Aldrich syndrome protein (WASp) causes severe abnormalities of the peripheral B-cell compartment in mice.

Bovine apolipoprotein B-100 is a dominant immunogen in therapeutic cell populations cultured in fetal calf serum in mice and humans

Broad spectrum of autoantibodies in patients with Wiskott-Aldrich syndrome and X-linked thrombocytopenia

Busulfan Pharmacokinetics in ADA SCID Gene Therapy

Clinical Manifestations and Pathophysiological Mechanisms of the Wiskott-Aldrich Syndrome.

Clinical efficacy of gene-modified stem cells in adenosine deaminase-deficient immunodeficiency

Cytokines and their role in lymphoid development, differentiation and homeostasis

Cytoreductive conditioning intensity predicts clonal diversity in ADA-SCID retroviral gene therapy patients

Defective inhibition of B-cell proliferation by Wiskott-Aldrich syndrome protein-deficient regulatory T cells

Development of IgA nephropathy-like glomerulonephritis associated with Wiskott–Aldrich syndrome protein deficiency ⬇️

Differential contribution of Wiskott-Aldrich syndrome protein to selective advantage in T- and B-cell lineages

Early-onset stroke and vasculopathy associated with mutations in ADA2

Efficient methods for targeted mutagenesis in zebrafish using zinc-finger nucleases: data from targeting of nine genes using CompoZr or CoDA ZFNs

Elevated IgE and atopy in patients treated for early-onset ADA-SCID.

FOXP3+ Tregs require WASP to restrain Th2-mediated food allergy

Foamy virus vector-mediated gene correction of a mouse model of Wiskott-Aldrich syndrome

Gene therapy for adenosine deaminase-deficient severe combined immune deficiency: clinical comparison of retroviral vectors and treatment plans.

Gene therapy in infants with severe combined immunodeficiency

Gene therapy model of X-linked severe combined immunodeficiency using a modified foamy virus vector

Gene therapy: X-SCID transgene leukaemogenicity

Gene transfer into hematopoietic stem cells as treatment for primary immunodeficiency diseases

High incidence of lymphomas in a subgroup of wiskott–aldrich syndrome patients ⬇️

Human adenylate kinase 2 deficiency causes a profound hematopoietic defect associated with sensorineural deafness

Improving cellular therapy for primary immune deficiency diseases: recognition, diagnosis, and management

In vitro functional correction of Hermansky-Pudlak Syndrome type-1 by lentiviral-mediated gene transfer

In vivo retroviral gene transfer by direct intrafemoral injection results in correction of the SCID phenotype in Jak3 knock-out animals ⬇️

Individualized iterative phenotyping for genome-wide analysis of loss-of-function mutations

Jak3 and the pathogenesis of severe combined immunodeficiency

Jak3, severe combined immunodeficiency, and a new class of immunosuppressive drugs.

Molecular and phenotypic abnormalities of B lymphocytes in patients with Wiskott-Aldrich syndrome

Molecular aspects of primary immunodeficiencies: lessons from cytokine and other signaling pathways.

Multicentric dermatofibrosarcoma protuberans in patients with adenosine deaminase-deficient severe combined immune deficiency

Multiple patients with revertant mosaicism in a single Wiskott-Aldrich syndrome family.

Myeloid dysplasia and bone marrow hypocellularity in adenosine deaminase-deficient severe combined immune deficiency.

N-WASP is required for B-cell-mediated autoimmunity in Wiskott-Aldrich syndrome.

Nuclear role of WASp in gene transcription is uncoupled from its ARP2/3-dependent cytoplasmic role in actin polymerization.

Nuclear role of WASp in the pathogenesis of dysregulated TH1 immunity in human Wiskott-Aldrich syndrome

Peptide library-based evaluation of T-cell receptor breadth detects defects in global and regulatory activation in human immunologic diseases

Persistence and expression of the adenosine deaminase gene for 12 years and immune reaction to gene transfer components: long-term results of the first clinical gene therapy trial.

Platelets from WAS patients show an increased susceptibility to ex vivo phagocytosis

Primary Immune Deficiency Treatment Consortium (PIDTC) report

Prolonged pancytopenia in a gene therapy patient with ADA-deficient SCID and trisomy 8 mosaicism: a case report

Reconstitution of lymphoid development and function in ZAP-70-deficient mice following gene transfer into bone marrow cells

Reduced Number of Dense Bodies and Reduced Serotonin Content in Platelets of Patients with Wiskott-Aldrich Syndrome. ⬇️

Reticular dysgenesis-associated AK2 protects hematopoietic stem and progenitor cell development from oxidative stress

Retroviral Transfer of Acidα-Glucosidase cDNA to Enzyme-Deficient Myoblasts Results in Phenotypic Spread of the Genotypic Correction by Both Secretion and Fusion ⬇️

Retrovirus-mediated WASP gene transfer corrects Wiskott-Aldrich syndrome T-cell dysfunction

Second-site mutation in the Wiskott-Aldrich syndrome (WAS) protein gene causes somatic mosaicism in two WAS siblings ⬇️

Self-inactivating retroviral vector-mediated gene transfer induces oncogene activation and immortalization of primary murine bone marrow cells

Somatic Mosaicism Caused by Monoallelic Reversion of a Mutation in T Cells of a Patient with ADA‐SCID and the Effects of Enzyme Replacement Therapy on the Revertant Phenotype ⬇️

Somatic mosaicism in the Wiskott-Aldrich syndrome: molecular and functional characterization of genotypic revertants

Systemic autoimmunity and defective Fas ligand secretion in the absence of the Wiskott-Aldrich syndrome protein

The altered landscape of the human skin microbiome in patients with primary immunodeficiencies

Type I interferonopathies in pediatric rheumatology