Lista de obras - Janet Shipley - Dominio Público Uruguay

8-Substituted Pyrido[3,4-d]pyrimidin-4(3H)-one Derivatives As Potent, Cell Permeable, KDM4 (JMJD2) and KDM5 (JARID1) Histone Lysine Demethylase Inhibitors

artículo científico publicado en 2016

ATR Is a Therapeutic Target in Synovial Sarcoma.

artículo científico publicado en 2017

Activation of the hedgehog pathway confers a poor prognosis in embryonal and fusion gene-negative alveolar rhabdomyosarcoma

article

Age-related biological features of germ cell tumors ⬇️

artículo científico

An additional human chromosome 21 causes suppression of neural fate of pluripotent mouse embryonic stem cells in a teratoma model

artículo científico publicado en 2007

Association between Large-scale Genomic Homozygosity without Chromosomal Loss and Nonseminomatous Germ Cell Tumor Development

article

Characterisation and chromosome mapping of the human non receptor tyrosine kinase gene, brk ⬇️

artículo científico publicado el 18 de septiembre de 1997

Chemosensitivity profiling of osteosarcoma tumour cell lines identifies a model of BRCAness

artículo científico publicado en 2018

Chromosomal imbalances associated with carcinoma in situ and associated testicular germ cell tumours of adolescents and adults.

artículo científico publicado en 2001

Chromosome 1q expression profiling and relapse in Wilms' tumour

scientific article published on 01 August 2002

Chromosome translocations in sarcomas and the analysis of paraffin-embedded material

artículo científico publicado en 1998

Clinical Application of Prognostic Gene Expression Signature in Fusion Gene-Negative Rhabdomyosarcoma: A Report from the Children's Oncology Group

artículo científico publicado en 2015

Clinical and biological significance of CXCL12 and CXCR4 expression in adult testes and germ cell tumours of adults and adolescents.

artículo científico publicado en 2009

Cloning and mapping of members of the MYM family

artículo científico publicado en 1999

Common variants identified in genome-wide association studies of testicular germ cell tumour: an update, biological insights and clinical application

artículo científico publicado en 2015

Comparative expressed sequence hybridization to chromosomes for tumor classification and identification of genomic regions of differential gene expression

artículo científico publicado en 2001

Comparative genomic hybridization and BUB1B mutation analyses in childhood cancers associated with mosaic variegated aneuploidy syndrome

article

DYRK1A-dosage imbalance perturbs NRSF/REST levels, deregulating pluripotency and embryonic stem cell fate in Down syndrome

artículo científico publicado en 2008

Defining a New Prognostic Index for Stage I Nonseminomatous Germ Cell Tumors Using CXCL12 Expression and Proportion of Embryonal Carcinoma.

artículo científico publicado en 2015

Defining minimum genomic regions of imbalance involved in testicular germ cell tumors of adolescents and adults through genome wide microarray analysis of cDNA clones

scientific article published on 01 December 2004

Development of a targeted sequencing approach to identify prognostic, predictive and diagnostic markers in paediatric solid tumours

artículo científico publicado en 2017

Diagnosis of Ewing's sarcoma and related tumours by detection of chromosome 22q12 translocations using fluorescence in situ hybridization on tumour touch imprints ⬇️

artículo científico publicado el 1 de junio de 1995

Differential regulation of MAP kinase activation by a novel splice variant of human MAP kinase phosphatase-2.

artículo científico publicado en 2010

Distinct Genetic and Epigenetic Changes in Medullary Breast Cancer

scientific article published on 01 July 2003

Distinct comparative genomic hybridisation profiles in gastric mucosa-associated lymphoid tissue lymphomas with and without t(11;18)(q21;q21).

artículo científico publicado en 2006

Distinct effects of ligand-induced PDGFRα and PDGFRβ signaling in the human rhabdomyosarcoma tumor cell and stroma cell compartments.

artículo científico publicado en 2013

Distinct roles for miR-1 and miR-133a in the proliferation and differentiation of rhabdomyosarcoma cells

artículo científico publicado en 2010

Dual blockade of the PI3K/AKT/mTOR (AZD8055) and RAS/MEK/ERK (AZD6244) pathways synergistically inhibits rhabdomyosarcoma cell growth in vitro and in vivo.

artículo científico publicado en 2013

Dual colour fluorescence in situ hybridization to paraffin-embedded samples to deduce the presence of the der(X)t(X;18)(p11.2;q11.2) and involvement of either the SSX1 or SSX2 gene: a diagnostic and prognostic aid for synovial sarcoma

artículo científico publicado en 1999

Endosialin expression in soft tissue sarcoma as a potential marker of undifferentiated mesenchymal cells

artículo científico publicado en 2016

Expression analysis onto microarrays of randomly selected cDNA clones highlights HOXB13 as a marker of human prostate cancer.

artículo científico publicado en 2005

Expression profiling targeting chromosomes for tumor classification and prediction of clinical behavior.

artículo científico publicado en 2003

Fluorescence in situ hybridization analysis of formalin fixed paraffin embedded tissues, including tissue microarrays.

artículo científico publicado en 2010

Fusion gene-negative alveolar rhabdomyosarcoma is clinically and molecularly indistinguishable from embryonal rhabdomyosarcoma.

artículo científico publicado en 2010

Fusion of splicing factor genes PSF and NonO (p54nrb) to the TFE3 gene in papillary renal cell carcinoma

artículo científico publicado en 1997

Fusion status in patients with lymph node-positive (N1) alveolar rhabdomyosarcoma is a powerful predictor of prognosis: Experience of the European Paediatric Soft Tissue Sarcoma Study Group (EpSSG)

artículo científico publicado en 2018

Gain of 1q is associated with adverse outcome in favorable histology Wilms' tumors

artículo científico publicado en 2001

Genomic and expression profiling of human spermatocytic seminomas: primary spermatocyte as tumorigenic precursor and DMRT1 as candidate chromosome 9 gene

artículo científico publicado en 2006

Genomic copy number and expression patterns in testicular germ cell tumours.

artículo científico publicado en 2007

Genomic gain and over expression of CCL2 correlate with vascular invasion in stage I non-seminomatous testicular germ-cell tumours.

artículo científico publicado en 2011

Genomic imbalances in rhabdomyosarcoma cell lines affect expression of genes frequently altered in primary tumors: an approach to identify candidate genes involved in tumor development

artículo científico publicado en 2009

Glypican-3 is expressed in rhabdomyosarcomas but not adult spindle cell and pleomorphic sarcomas.

artículo científico publicado en 2011

HES6 enhances the motility of alveolar rhabdomyosarcoma cells.

artículo científico publicado en 2012

Hypoxia and its therapeutic possibilities in paediatric cancers

artículo científico publicado en 2020

ICAAR, a novel member of a new family of transmembrane, tyrosine phosphatase-like proteins.

artículo científico publicado en 1996

IGF1R signalling in testicular germ cell tumour cells impacts on cell survival and acquired cisplatin resistance

artículo científico publicado en 2017

Identification of 19 new risk loci and potential regulatory mechanisms influencing susceptibility to testicular germ cell tumor ⬇️

artículo científico publicado en 2017

Identification of ZDHHC14 as a novel human tumour suppressor gene.

artículo científico publicado en 2014

Identification of four new susceptibility loci for testicular germ cell tumour ⬇️

artículo científico publicado en 2015

Identification of nine new susceptibility loci for testicular cancer, including variants near DAZL and PRDM14

artículo científico publicado en 2013

Identification of novel genes, SYT and SSX, involved in the t(X;18)(p11.2;q11.2) translocation found in human synovial sarcoma

artículo científico publicado en 1994

Immunohistochemical detection of glypican-5 in paraffin-embedded material: an optimized method for a novel research antibody.

artículo científico publicado en 2012

Impact of fusion gene status versus histology on risk-stratification for rhabdomyosarcoma: Retrospective analyses of patients on UK trials.

artículo científico publicado en 2016

Inconvenience of convenience cohorts--letter.

artículo científico publicado en 2012

Increased level of chromosomal damage after irradiation of lymphocytes from BRCA1 mutation carriers

artículo científico publicado en 2006

Interphase fluorescence in situ hybridization detection of t(2;13)(q35;q14) in alveolar rhabdomyosarcoma--a diagnostic tool in minimally invasive biopsies

artículo científico publicado en 1996

JARID2 is a direct target of the PAX3-FOXO1 fusion protein and inhibits myogenic differentiation of rhabdomyosarcoma cells.

artículo científico publicado en 2013

KIT and RAS signalling pathways in testicular germ cell tumours: new data and a review of the literature.

artículo científico publicado en 2007

Less Can Be More for Gene Dose and Drug Sensitivity.

artículo científico publicado en 2015

Loss of 13q14-q21 and gain of 5p14-pter in the progression of leiomyosarcoma.

artículo científico publicado en 2003

Mapping of a translocation breakpoint in a Peutz-Jeghers hamartoma to the putative PJS locus at 19q13.4 and mutation analysis of candidate genes in polyp and STK11-negative PJS cases

artículo científico publicado en 2004

Mapping the X chromosome breakpoint in two papillary renal cell carcinoma cell lines with a t(X;1)(p11.2;q21.2) and the first report of a female case.

artículo científico publicado en 1995

MicroRNA and gene co-expression networks characterize biological and clinical behavior of rhabdomyosarcomas.

artículo científico publicado en 2016

Minimum regions of genomic imbalance in stage I testicular embryonal carcinoma and association of 22q loss with relapse.

artículo científico publicado en 2010

Molecular characterisation of the t(1;15)(p22;q22) translocation in the prostate cancer cell line LNCaP.

artículo científico publicado en 2006

Molecular cytogenetic analysis consistently identifies translocations involving chromosomes 1, 2 and 15 in five embryonal rhabdomyosarcoma cell lines and a PAX-FOXO1A fusion gene negative alveolar rhabdomyosarcoma cell line.

artículo científico

Mutations of the BRAF gene in human cancer

artículo científico publicado en 2002

Nascent pre-rRNA overexpression correlates with an adverse prognosis in alveolar rhabdomyosarcoma

scientific article published on 01 September 2006

No evidence for epigenetic inactivation of fumarate hydratase in leiomyomas and leiomyosarcomas

article

Novel formation and amplification of the PAX7-FKHR fusion gene in a case of alveolar rhabdomyosarcoma

artículo científico publicado en 1996

Nuclear overexpression of the E2F3 transcription factor in human lung cancer.

artículo científico publicado en 2006

Overexpression of genes on 16q associated with cisplatin resistance of testicular germ cell tumor cell lines.

artículo científico publicado en 2005

PAX3/FOXO1 fusion gene status is the key prognostic molecular marker in rhabdomyosarcoma and significantly improves current risk stratification.

artículo científico publicado en 2012

PAX7 expression in embryonal rhabdomyosarcoma suggests an origin in muscle satellite cells

artículo científico publicado en 2003

Pez: a novel human cDNA encoding protein tyrosine phosphatase- and ezrin-like domains

artículo científico publicado en 1995

Phyllodes tumors of the breast analyzed by comparative genomic hybridization and association of increased 1q copy number with stromal overgrowth and recurrence

artículo científico publicado el 1 de noviembre de 1997

Polygenic susceptibility to testicular cancer: implications for personalised health care

artículo científico publicado en 2015

Putting the colours into chromogenic in situ hybridization (CISH)

artículo científico publicado en 2006

Rapid and accurate determination of MYCN copy number and 1p deletion in neuroblastoma by quantitative PCR.

artículo científico publicado en 2006

Relationship between MYCN copy number and expression in rhabdomyosarcomas and correlation with adverse prognosis in the alveolar subtype

artículo científico publicado en 2005

Rhabdomyosarcoma subtyping by immunohistochemical assessment of myogenin: tissue array study and review of the literature.

artículo científico publicado en 2008

Rhabdomyosarcoma: current challenges and their implications for developing therapies.

artículo científico publicado en 2014

Stem cell factor as a novel diagnostic marker for early malignant germ cells.

artículo científico publicado en 2008

TEAD1 and c-Cbl are novel prostate basal cell markers that correlate with poor clinical outcome in prostate cancer.

artículo científico publicado en 2008

Targeting the insulin-like growth factor pathway in rhabdomyosarcomas: rationale and future perspectives.

artículo científico publicado en 2011

Testicular germ cell tumours: predisposition genes and the male germ cell niche.

artículo científico publicado en 2011

Testicular germ-cell cancer.

artículo científico publicado en 2006

The Hippo transducer YAP1 transforms activated satellite cells and is a potent effector of embryonal rhabdomyosarcoma formation.

artículo científico publicado en 2014

The Polycomb group (PcG) protein EZH2 supports the survival of PAX3-FOXO1 alveolar rhabdomyosarcoma by repressing FBXO32 (Atrogin1/MAFbx).

artículo científico publicado en 2013

The SYT protein involved in the t(X;18) synovial sarcoma translocation is a transcriptional activator localised in nuclear bodies

artículo científico publicado el 1 de septiembre de 1997

The SYT-SSX1 fusion type of synovial sarcoma is associated with increased expression of cyclin A and D1. A link between t(X;18)(p11.2; q11.2) and the cell cycle machinery

scientific article published on 01 August 2002

The genomic landscape of testicular germ cell tumours: from susceptibility to treatment

artículo científico publicado en 2016

The long non-coding RNA MYCNOS-01 regulates MYCN protein levels and affects growth of MYCN-amplified rhabdomyosarcoma and neuroblastoma cells.

artículo científico publicado en 2018

Whole-exome sequencing reveals the mutational spectrum of testicular germ cell tumours

artículo científico publicado en 2015

Lista de obras de Janet Shipley

8-Substituted Pyrido[3,4-d]pyrimidin-4(3H)-one Derivatives As Potent, Cell Permeable, KDM4 (JMJD2) and KDM5 (JARID1) Histone Lysine Demethylase Inhibitors

ATR Is a Therapeutic Target in Synovial Sarcoma.

Activation of the hedgehog pathway confers a poor prognosis in embryonal and fusion gene-negative alveolar rhabdomyosarcoma

Age-related biological features of germ cell tumors ⬇️

An additional human chromosome 21 causes suppression of neural fate of pluripotent mouse embryonic stem cells in a teratoma model

Association between Large-scale Genomic Homozygosity without Chromosomal Loss and Nonseminomatous Germ Cell Tumor Development

Characterisation and chromosome mapping of the human non receptor tyrosine kinase gene, brk ⬇️

Chemosensitivity profiling of osteosarcoma tumour cell lines identifies a model of BRCAness

Chromosomal imbalances associated with carcinoma in situ and associated testicular germ cell tumours of adolescents and adults.

Chromosome 1q expression profiling and relapse in Wilms' tumour

Chromosome translocations in sarcomas and the analysis of paraffin-embedded material

Clinical Application of Prognostic Gene Expression Signature in Fusion Gene-Negative Rhabdomyosarcoma: A Report from the Children's Oncology Group

Clinical and biological significance of CXCL12 and CXCR4 expression in adult testes and germ cell tumours of adults and adolescents.

Cloning and mapping of members of the MYM family

Common variants identified in genome-wide association studies of testicular germ cell tumour: an update, biological insights and clinical application

Comparative expressed sequence hybridization to chromosomes for tumor classification and identification of genomic regions of differential gene expression

Comparative genomic hybridization and BUB1B mutation analyses in childhood cancers associated with mosaic variegated aneuploidy syndrome

DYRK1A-dosage imbalance perturbs NRSF/REST levels, deregulating pluripotency and embryonic stem cell fate in Down syndrome

Defining a New Prognostic Index for Stage I Nonseminomatous Germ Cell Tumors Using CXCL12 Expression and Proportion of Embryonal Carcinoma.

Defining minimum genomic regions of imbalance involved in testicular germ cell tumors of adolescents and adults through genome wide microarray analysis of cDNA clones

Development of a targeted sequencing approach to identify prognostic, predictive and diagnostic markers in paediatric solid tumours

Diagnosis of Ewing's sarcoma and related tumours by detection of chromosome 22q12 translocations using fluorescence in situ hybridization on tumour touch imprints ⬇️

Differential regulation of MAP kinase activation by a novel splice variant of human MAP kinase phosphatase-2.

Distinct Genetic and Epigenetic Changes in Medullary Breast Cancer

Distinct comparative genomic hybridisation profiles in gastric mucosa-associated lymphoid tissue lymphomas with and without t(11;18)(q21;q21).

Distinct effects of ligand-induced PDGFRα and PDGFRβ signaling in the human rhabdomyosarcoma tumor cell and stroma cell compartments.

Distinct roles for miR-1 and miR-133a in the proliferation and differentiation of rhabdomyosarcoma cells

Dual blockade of the PI3K/AKT/mTOR (AZD8055) and RAS/MEK/ERK (AZD6244) pathways synergistically inhibits rhabdomyosarcoma cell growth in vitro and in vivo.

Dual colour fluorescence in situ hybridization to paraffin-embedded samples to deduce the presence of the der(X)t(X;18)(p11.2;q11.2) and involvement of either the SSX1 or SSX2 gene: a diagnostic and prognostic aid for synovial sarcoma

Endosialin expression in soft tissue sarcoma as a potential marker of undifferentiated mesenchymal cells

Expression analysis onto microarrays of randomly selected cDNA clones highlights HOXB13 as a marker of human prostate cancer.

Expression profiling targeting chromosomes for tumor classification and prediction of clinical behavior.

Fluorescence in situ hybridization analysis of formalin fixed paraffin embedded tissues, including tissue microarrays.

Fusion gene-negative alveolar rhabdomyosarcoma is clinically and molecularly indistinguishable from embryonal rhabdomyosarcoma.

Fusion of splicing factor genes PSF and NonO (p54nrb) to the TFE3 gene in papillary renal cell carcinoma

Fusion status in patients with lymph node-positive (N1) alveolar rhabdomyosarcoma is a powerful predictor of prognosis: Experience of the European Paediatric Soft Tissue Sarcoma Study Group (EpSSG)

Gain of 1q is associated with adverse outcome in favorable histology Wilms' tumors

Genomic and expression profiling of human spermatocytic seminomas: primary spermatocyte as tumorigenic precursor and DMRT1 as candidate chromosome 9 gene

Genomic copy number and expression patterns in testicular germ cell tumours.

Genomic gain and over expression of CCL2 correlate with vascular invasion in stage I non-seminomatous testicular germ-cell tumours.

Genomic imbalances in rhabdomyosarcoma cell lines affect expression of genes frequently altered in primary tumors: an approach to identify candidate genes involved in tumor development

Glypican-3 is expressed in rhabdomyosarcomas but not adult spindle cell and pleomorphic sarcomas.

HES6 enhances the motility of alveolar rhabdomyosarcoma cells.

Hypoxia and its therapeutic possibilities in paediatric cancers

ICAAR, a novel member of a new family of transmembrane, tyrosine phosphatase-like proteins.

IGF1R signalling in testicular germ cell tumour cells impacts on cell survival and acquired cisplatin resistance

Identification of 19 new risk loci and potential regulatory mechanisms influencing susceptibility to testicular germ cell tumor ⬇️

Identification of ZDHHC14 as a novel human tumour suppressor gene.

Identification of four new susceptibility loci for testicular germ cell tumour ⬇️

Identification of nine new susceptibility loci for testicular cancer, including variants near DAZL and PRDM14

Identification of novel genes, SYT and SSX, involved in the t(X;18)(p11.2;q11.2) translocation found in human synovial sarcoma

Immunohistochemical detection of glypican-5 in paraffin-embedded material: an optimized method for a novel research antibody.

Impact of fusion gene status versus histology on risk-stratification for rhabdomyosarcoma: Retrospective analyses of patients on UK trials.

Inconvenience of convenience cohorts--letter.

Increased level of chromosomal damage after irradiation of lymphocytes from BRCA1 mutation carriers

Interphase fluorescence in situ hybridization detection of t(2;13)(q35;q14) in alveolar rhabdomyosarcoma--a diagnostic tool in minimally invasive biopsies

JARID2 is a direct target of the PAX3-FOXO1 fusion protein and inhibits myogenic differentiation of rhabdomyosarcoma cells.

KIT and RAS signalling pathways in testicular germ cell tumours: new data and a review of the literature.

Less Can Be More for Gene Dose and Drug Sensitivity.

Loss of 13q14-q21 and gain of 5p14-pter in the progression of leiomyosarcoma.

Mapping of a translocation breakpoint in a Peutz-Jeghers hamartoma to the putative PJS locus at 19q13.4 and mutation analysis of candidate genes in polyp and STK11-negative PJS cases

Mapping the X chromosome breakpoint in two papillary renal cell carcinoma cell lines with a t(X;1)(p11.2;q21.2) and the first report of a female case.

MicroRNA and gene co-expression networks characterize biological and clinical behavior of rhabdomyosarcomas.

Minimum regions of genomic imbalance in stage I testicular embryonal carcinoma and association of 22q loss with relapse.

Molecular characterisation of the t(1;15)(p22;q22) translocation in the prostate cancer cell line LNCaP.

Molecular cytogenetic analysis consistently identifies translocations involving chromosomes 1, 2 and 15 in five embryonal rhabdomyosarcoma cell lines and a PAX-FOXO1A fusion gene negative alveolar rhabdomyosarcoma cell line.

Mutations of the BRAF gene in human cancer

Nascent pre-rRNA overexpression correlates with an adverse prognosis in alveolar rhabdomyosarcoma

No evidence for epigenetic inactivation of fumarate hydratase in leiomyomas and leiomyosarcomas

Novel formation and amplification of the PAX7-FKHR fusion gene in a case of alveolar rhabdomyosarcoma

Nuclear overexpression of the E2F3 transcription factor in human lung cancer.

Overexpression of genes on 16q associated with cisplatin resistance of testicular germ cell tumor cell lines.

PAX3/FOXO1 fusion gene status is the key prognostic molecular marker in rhabdomyosarcoma and significantly improves current risk stratification.

PAX7 expression in embryonal rhabdomyosarcoma suggests an origin in muscle satellite cells

Pez: a novel human cDNA encoding protein tyrosine phosphatase- and ezrin-like domains

Phyllodes tumors of the breast analyzed by comparative genomic hybridization and association of increased 1q copy number with stromal overgrowth and recurrence

Polygenic susceptibility to testicular cancer: implications for personalised health care

Putting the colours into chromogenic in situ hybridization (CISH)

Rapid and accurate determination of MYCN copy number and 1p deletion in neuroblastoma by quantitative PCR.