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Lista de obras de Chris Jones

A PML/Slit Axis Controls Physiological Cell Migration and Cancer Invasion in the CNS.

artículo científico publicado en 2017

A distinct spectrum of copy number aberrations in pediatric high-grade gliomas

artículo científico publicado en 2010

A role for fibrillar collagen deposition and the collagen internalization receptor endo180 in glioma invasion

artículo científico publicado en 2010

A subset of pediatric-type thalamic gliomas share a distinct DNA methylation profile, H3K27me3 loss and frequent alteration of EGFR

scientific article published on 01 November 2020

A tailored molecular profiling programme for children with cancer to identify clinically actionable genetic alterations

scientific article published on 19 September 2019

ACVR1 mutations in DIPG: lessons learned from FOP.

artículo científico publicado en 2014

ALK2 inhibitors display beneficial effects in preclinical models of mutant diffuse intrinsic pontine glioma

article

ATM regulates 3-methylpurine-DNA glycosylase and promotes therapeutic resistance to alkylating agents

artículo científico publicado en 2014

ATRX loss promotes tumor growth and impairs nonhomologous end joining DNA repair in glioma

artículo científico publicado en 2016

Acquired resistance to 17-allylamino-17-demethoxygeldanamycin (17-AAG, tanespimycin) in glioblastoma cells

scientific article published on 24 February 2009

Adult recurrent pilocytic astrocytoma: Clinical, histopathological and molecular study

artículo científico publicado en 2015

Allele loss at 16q defines poorer prognosis Wilms tumour irrespective of treatment approach in the UKW1-3 clinical trials: a Children's Cancer and Leukaemia Group (CCLG) Study

artículo científico publicado en 2009

Amplification and overexpression of CACNA1E correlates with relapse in favorable histology Wilms' tumors

artículo científico publicado en 2006

An epigenetically controlled PML/Slit axis at the root of cell migration in both normal and neoplastic cells in the CNS

An immunohistochemical investigation into the presence and localization of cytochrome P-450 isozymes in organogenesis-stage rat conceptal tissue

scientific article published on 01 November 1993

An integrative genomic and transcriptomic analysis reveals molecular pathways and networks regulated by copy number aberrations in basal-like, HER2 and luminal cancers

artículo científico publicado en 2009

Analysis by array CGH of genomic changes associated with the progression or relapse of Wilms' tumour

artículo científico publicado en 2007

Analysis of EGFR overexpression, EGFR gene amplification and the EGFRvIII mutation in Portuguese high-grade gliomas

article

Array CGH profiling of favourable histology Wilms tumours reveals novel gains and losses associated with relapse

artículo científico publicado en 2006

Array CGH using whole genome amplification of fresh-frozen and formalin-fixed, paraffin-embedded tumor DNA.

artículo científico publicado en 2005

Audit of transvaginal sonography of normal postmenopausal ovaries by sonographers from the United Kingdom Collaborative Trial of Ovarian Cancer Screening (UKCTOCS)

scholarly article by Will Stott published in January 2018

BT-05FUNCTIONAL DIVERSITY AND CO-OPERATIVITY OF SUBCLONAL POPULATIONS OF PAEDIATRIC GLIOBLASTOMA AND DIFFUSE INTRINSIC PONTINE GLIOMA CELLS.

artículo científico publicado en 2015

Basal-like grade III invasive ductal carcinoma of the breast: patterns of metastasis and long-term survival ⬇️

artículo científico publicado en 2007

Biological material collection to advance translational research and treatment of children with CNS tumours: position paper from the SIOPE Brain Tumour Group

article

Blastemal expression of type I insulin-like growth factor receptor in Wilms' tumors is driven by increased copy number and correlates with relapse.

artículo científico publicado en 2006

CGH analysis of ductal carcinoma of the breast with basaloid/myoepithelial cell differentiation.

artículo científico publicado en 2001

CNS-PNETs with C19MC amplification and/or LIN28 expression comprise a distinct histogenetic diagnostic and therapeutic entity

artículo científico publicado en 2014

Caveolin 1 is overexpressed and amplified in a subset of basal-like and metaplastic breast carcinomas: a morphologic, ultrastructural, immunohistochemical, and in situ hybridization analysis

artículo científico publicado en 2007

Challenging the indiscriminate use of temozolomide in pediatric high-grade gliomas: A review of past, current, and emerging therapies

scientific article published on 16 October 2019

Characterising the TP53-deleted subgroup of chronic lymphocytic leukemia: an analysis of additional cytogenetic abnormalities detected by interphase fluorescence in situ hybridisation and array-based comparative genomic hybridisation

scientific article published on 01 October 2008

Characterization of the transcriptional and metabolic responses of pediatric high grade gliomas to mTOR-HIF-1α axis inhibition

artículo científico publicado en 2017

Characterizing and targeting PDGFRA alterations in pediatric high-grade glioma

artículo científico publicado en 2016

Childhood brain tumours as epigenetic diseases

artículo científico publicado en 2020

Clinical, Radiologic, Pathologic, and Molecular Characteristics of Long-Term Survivors of Diffuse Intrinsic Pontine Glioma (DIPG): A Collaborative Report From the International and European Society for Pediatric Oncology DIPG Registries.

artículo científico publicado en 2018

Columnar cell lesions of the breast: the missing link in breast cancer progression? A morphological and molecular analysis

artículo científico publicado en 2005

Common alleles in candidate susceptibility genes associated with risk and development of epithelial ovarian cancer

artículo científico publicado en 2011

Common variants at 19p13 are associated with susceptibility to ovarian cancer

artículo científico publicado en 2010

Comparative genomic hybridisation analysis of myoepithelial carcinoma of the breast.

artículo científico publicado en 2000

Comparative genomic hybridization analysis of bilateral hyperplasia of usual type of the breast

artículo científico publicado en 2003

Complex patterns of chromosome 9 alterations including the p16INK4a locus in Wilms tumours

artículo científico publicado en 2007

Copy Number Profiling of Brazilian Astrocytomas

artículo científico publicado en 2016

Correction to: International experience in the development of patient-derived xenograft models of diffuse intrinsic pontine glioma

artículo científico publicado en 2019

Correction: Frequent Long-Range Epigenetic Silencing of Protocadherin Gene Clusters on Chromosome 5q31 in Wilms' Tumor

article

DETAILED MOLECULAR CHARACTERISATION OF DIFFUSE INTRINSIC PONTINE GLIOMAS IDENTIFIES THREE MOLECULAR SUBGROUPS AND A NOVEL CANCER DRIVER, ACVR1.

artículo científico publicado en 2014

DIPG-08. THE ROLE OF KMT5B/C AND H4K20 DI/TRIMETHYLATION IN DIPG

DIPG-11. NEURAL PRECURSOR CELL:GLIOMA INTERACTIONS MEDIATE TUMOR COLONIZATION OF THE SUBVENTRICULAR ZONE BY DIPG.

artículo científico publicado en 2017

DIPG-25. GENETIC ALTERATIONS TARGETING THE MAPK PATHWAY CONFERS PRECLINICAL SENSITIVITY TO TRAMETINIB IN A CO-CLINICAL TRIAL IN DIPG

DIPG-28. NTRK FUSIONS IN PEDIATRIC DIFFUSE INTRINSIC PONTINE GLIOMAS

artículo científico publicado en 2019

DIPG-29. PRECLINICAL EFFICACY OF COMBINED ACVR1 AND PI3K/mTOR INHIBITION IN DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG).

artículo científico publicado en 2018

DIPG-35. OPEN DIPG INITIATIVE: A PLATFORM FOR ACCELERATING DISCOVERY THROUGH DATA ACCESS, CONSOLIDATION AND HARMONIZATION

artículo científico publicado en 2019

DIPG-40. Combined pharmacological and genetic screening to identify dependencies and combinations in ACVR1-mutant diffuse midline glioma

artículo científico publicado en 2022

DIPG-40. TARGETING MASTER REGULATOR DEPENDENCIES IN DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG)

artículo científico publicado en 2020

DIPG-49. STAT3 AS A THERAPEUTIC TARGET IN DIPG

DNA methylation-based classification of central nervous system tumours

artículo científico publicado en 2018

DNA methylation-based profiling for paediatric CNS tumour diagnosis and treatment: a population-based study

artículo científico publicado en 2019

Delineation of a 1Mb breakpoint region at 1p13 in Wilms tumors by fine-tiling oligonucleotide array CGH

scientific article published on 01 June 2007

Dependence of Wilms tumor cells on signaling through insulin-like growth factor 1 in an orthotopic xenograft model targetable by specific receptor inhibition.

artículo científico publicado en 2012

Development of a targeted sequencing approach to identify prognostic, predictive and diagnostic markers in paediatric solid tumours

artículo científico publicado en 2017

Development of the SIOPE DIPG network, registry and imaging repository: a collaborative effort to optimize research into a rare and lethal disease

artículo científico publicado en 2017

Distinct phenotypic differences associated with differential amplification of receptor tyrosine kinase genes at 4q12 in glioblastoma

artículo científico publicado en 2013

Distribution and significance of 14-3-3sigma, a novel myoepithelial marker, in normal, benign, and malignant breast tissue

artículo científico publicado en 2004

EAPH-05. MOLECULAR PROFILING AND IDENTIFICATION OF TARGETED THERAPIES FOR CHILDREN AND YOUNG ADULTS WITH PRIMARY CENTRAL NERVOUS SYSTEM TUMOURS IN THE UNITED KINGDOM

EGFR amplification and lack of activating mutations in metaplastic breast carcinomas

article

EGFRvIII deletion mutations in pediatric high-grade glioma and response to targeted therapy in pediatric glioma cell lines

artículo científico

EMBR-17. PINEOBLASTOMA SEGREGATES INTO MOLECULAR SUBTYPES WITH DISTINCT CLINICOPATHOLOGIC FEATURES: REPORT FROM THE RARE BRAIN TUMOR CONSORTIUM

Endoplasmic reticulum stress-inducing drugs sensitize glioma cells to temozolomide through downregulation of MGMT, MPG, and Rad51

artículo científico publicado en 2016

Endosialin (CD248) is a marker of tumor-associated pericytes in high-grade glioma

artículo científico

Enhanced efficacy of IGF1R inhibition in pediatric glioblastoma by combinatorial targeting of PDGFRα/β.

artículo científico publicado en 2011

Erratum: Corrigendum: Common variants at 19p13 are associated with susceptibility to ovarian cancer

scholarly article published in Nature Genetics

Euphol, a tetracyclic triterpene, from Euphorbia tirucalli induces autophagy and sensitizes temozolomide cytotoxicity on glioblastoma cells.

artículo científico publicado en 2018

Evaluation of Phi29-based whole-genome amplification for microarray-based comparative genomic hybridisation

artículo científico publicado en 2007

Evaluation of a novel antibody to define histone 3.3 G34R mutant brain tumours

artículo científico publicado en 2017

Evaluation of clinically translatable MR imaging biomarkers of therapeutic response in the TH-MYCN transgenic mouse model of neuroblastoma

artículo científico publicado en 2012

Evaluation of the Response of Intracranial Xenografts to VEGF Signaling Inhibition Using Multiparametric MRI

artículo científico publicado en 2017

Exploring the biomechanical properties of brain malignancies and their pathologic determinants in vivo with magnetic resonance elastography

artículo científico publicado en 2015

Expression of ATM, p53, and the MRE11-Rad50-NBS1 complex in myoepithelial cells from benign and malignant proliferations of the breast

artículo científico publicado en 2004

Expression of hepatocyte growth factor and its receptor met in Wilms' tumors and nephrogenic rests reflects their roles in kidney development

artículo científico publicado en 2009

Expression profiling of purified normal human luminal and myoepithelial breast cells: identification of novel prognostic markers for breast cancer

artículo científico publicado en 2004

Expression profiling using cDNA microarrays

scientific article published on 01 January 2006

FGFR1 emerges as a potential therapeutic target for lobular breast carcinomas

artículo científico publicado en 2006

Frequency and Heritability ofWT1Mutations in Nonsyndromic Wilms' Tumor Patients: A UK Children’s Cancer Study Group Study

Frequent long-range epigenetic silencing of protocadherin gene clusters on chromosome 5q31 in Wilms' tumor

artículo científico publicado en 2009

Functional diversity and cooperativity between subclonal populations of pediatric glioblastoma and diffuse intrinsic pontine glioma cells.

artículo científico publicado en 2018

Gene expression analysis using filter cDNA microarrays

article

Genetic alterations in 'normal' luminal and myoepithelial cells of the breast

artículo científico publicado en 1999

Genomic analysis of diffuse intrinsic pontine gliomas identifies three molecular subgroups and recurrent activating ACVR1 mutations

artículo científico publicado en 2014

Genomic analysis of the HER2/TOP2A amplicon in breast cancer and breast cancer cell lines

artículo científico publicado en 2008

Genotypic selection of mutated DNA sequences using mismatch cleavage analysis, a possible basis for novel mutation assays

artículo científico publicado en 1997

Germline-driven replication repair-deficient high-grade gliomas exhibit unique hypomethylation patterns

artículo científico publicado en 2020

Glioblastoma blood flow measured with stable xenon CT indicates tumor necrosis, vascularity, and brain invasion

artículo científico publicado en 2012

H3-/IDH-wild type pediatric glioblastoma is comprised of molecularly and prognostically distinct subtypes with associated oncogenic drivers

artículo científico publicado en 2017

HG-09INFANTILE GLIOBLASTOMA WITH SARCOMATOUS HISTOLOGY DRIVEN BY ETV6:NTRK3 FUSIONS ARE SENSITIVE TO TRK INHIBITION BY PHA-848125.

artículo científico publicado en 2015

HG-11INTEGRATIVE MOLECULAR META-ANALYSIS OF 700 PEDIATRIC HIGH GRADE GLIOMA AND DIPG DEFINES WIDESPREAD INTER- AND INTRA-TUMORAL HETEROGENEITY.

artículo científico publicado en 2015

HG-128BO25041 - A PHASE II OPEN-LABEL, RANDOMIZED, MULTI CENTRE COMPARATIVE STUDY OF BEVACIZUMAB BASED THERAPY IN PAEDIATRIC PATIENTS WITH NEWLY DIAGNOSED SUPRATENTORIAL, INFRATENTORIAL CEREBELLAR, OR PEDUNCULAR HIGH GRADE GLIOMA.

artículo científico publicado en 2016

HG-14CLINICAL, RADIOGRAPHIC, AND HISTOLOGIC CHARACTERISTICS OF LONG-TERM SURVIVORS OF DIFFUSE INTRINSIC PONTINE GLIOMA: A REPORT FROM THE INTERNATIONAL DIPG REGISTRY.

artículo científico publicado en 2015

HG-67PRECLINICAL EFFICACY OF ALK2 INHIBITORS IN ACVR1 MUTANT DIPG.

artículo científico publicado en 2016

HG-72DIPG CELLS ESCAPE THE PONS EARLY DURING TUMOUR EVOLUTION.

artículo científico publicado en 2016

HG-75CLINICAL, RADIOLOGICAL, AND HISTO-GENETIC CHARACTERISTICS OF LONG-TERM SURVIVORS OF DIFFUSE INTRINSIC PONTINE GLIOMA: A COLLABORATIVE REPORT FROM THE INTERNATIONAL AND SIOP-E DIPG REGISTRIES.

artículo científico publicado en 2016

HG-85INTER-OBSERVER AGREEMENT IN NEUROPATHOLOGICAL HGG DIAGNOSIS : EXPERIENCE OF THE PRE-RANDOMISATION CENTRAL REVIEW IN THE HERBY TRIAL.

artículo científico publicado en 2016

HG-88NOVEL ANTIBODIES TO STUDY HISTONE H3.3 MUTATIONS IN DIPG AND pHGG.

artículo científico publicado en 2016

HG-95INTEGRATED MOLECULAR META-ANALYSIS OF 1000 PAEDIATRIC HIGH GRADE GLIOMA AND DIPG.

artículo científico publicado en 2016

HG-97PAEDIATRIC GBM AND DIPG SUBCLONES CO-OPERATE TO PROMOTE TUMORIGENESIS.

artículo científico publicado en 2016

HG-99A PATIENT-DERIVED PAEDIATRIC HIGH GRADE GLIOMA AND DIPG CELL CULTURE PANEL RECAPITULATING THE GENOTYPIC AND PHENOTYPIC DIVERSITY OF THE DISEASE.

artículo científico publicado en 2016

HGG-03. INTEGRATED MOLECULAR AND PATHOLOGICAL CHARACTERISATION OF NON-BRAINSTEM PAEDIATRIC HIGH GRADE GLIOMA FROM THE HERBY PHASE II RANDOMISED TRIAL.

artículo científico publicado en 2017

HGG-06. EARLY GABAERGIC NEURONAL LINEAGE DEFINES DEPENDENCIES IN HISTONE H3 G34R/V GLIOMA

artículo científico publicado en 2021

HGG-07. MUTATIONS IN ATRX INCREASE GENETIC INSTABILITY AND SENSITIVITY TO PARP INHIBITORS IN PAEDIATRIC GLIOBLASTOMA CELLS.

artículo científico publicado en 2017

HGG-13. SURVIVAL OUTCOMES OF CHILDREN AND ADOLESCENTS WITH BI-THALAMIC GLIOMAS: THE SOUTH THAMES NEURO-ONCOLOGY UNIT EXPERIENCE

HGG-17. SINGLE-CELL AND SPATIAL ANALYSES DECIPHER THE UNIQUE INVASIVE GROWTH PATTERN OF GLIOMATOSIS CEREBRI

scientific article published in 2023

HGG-18. MOLECULAR PATHOPHYSIOLOGY OF HISTONE G34R MUTANT CHILDHOOD BRAIN TUMOURS; TOWARDS THE DEVELOPMENT OF NOVEL TARGETED THERAPIES

HGG-23. DRUG SCREENING LINKED TO MOLECULAR PROFILING IDENTIFIES NOVEL DEPENDENCIES IN PATIENT-DERIVED PRIMARY CULTURES OF PAEDIATRIC HIGH GRADE GLIOMA AND DIPG

article by Alan Mackay et al published 22 June 2018 in Neuro-Oncology

HGG-24. MOLECULAR, PATHOLOGICAL, RADIOLOGICAL AND IMMUNE PROFILING OF NON-BRAINSTEM PAEDIATRIC HIGH GRADE GLIOMA FROM THE HERBY PHASE II RANDOMISED TRIAL

artículo científico publicado en 2018

HGG-25. INFANT GLIOMAS COMPRISE MULTIPLE BIOLOGICAL AND CLINICOPATHOLOGICAL SUBGROUPS

HGG-37. PAEDIATRIC GLIOBLASTOMA CELLS SHOW CRITICAL DEPENDENCIES ON EPIGENOMIC AND EPITRANSCRIPTOMIC CONTROL OF GENE EXPRESSION BY H3.3G34R/V MUTATIONS

artículo científico publicado en 2020

Histologically distinct neuroepithelial tumors with histone 3 G34 mutation are molecularly similar and comprise a single nosologic entity

artículo científico publicado en 2015

Histone H3 wild-type DIPG/DMG overexpressing EZHIP extend the spectrum diffuse midline gliomas with PRC2 inhibition beyond H3-K27M mutation

scientific article published on 19 March 2020

Histone H3.3. mutations drive pediatric glioblastoma through upregulation of MYCN.

artículo científico publicado en 2013

Histone H3.3K27M Mobilizes Multiple Cancer/Testis (CT) Antigens in Pediatric Glioma

artículo científico publicado en 2018

Histone H3F3A and HIST1H3B K27M mutations define two subgroups of diffuse intrinsic pontine gliomas with different prognosis and phenotypes

artículo científico publicado en 2015

Hypoxic Environment and Paired Hierarchical 3D and 2D Models of Pediatric H3.3-Mutated Gliomas Recreate the Patient Tumor Complexity

scientific article published on 26 November 2019

IDH1-associated primary glioblastoma in young adults displays differential patterns of tumour and vascular morphology

artículo científico publicado en 2013

Identification of the familial cylindromatosis tumour-suppressor gene

artículo científico publicado en 2000

ImmunoPET in pontine glioma : more than meets the eye ?

artículo científico publicado en 2017

In vitro nuclear magnetic resonance spectroscopy metabolic biomarkers for the combination of temozolomide with PI3K inhibition in paediatric glioblastoma cells

artículo científico

Infant high grade gliomas comprise multiple subgroups characterized by novel targetable gene fusions and favorable outcomes

scientific article published on 01 April 2020

Integrated Molecular Meta-Analysis of 1,000 Pediatric High-Grade and Diffuse Intrinsic Pontine Glioma

artículo científico publicado en 2017

Integrated molecular genetic profiling of pediatric high-grade gliomas reveals key differences with the adult disease

artículo científico publicado en 2010

Integration of Multiple Platforms for the Analysis of Multifluorescent Marking Technology Applied to Pediatric GBM and DIPG

scientific article published on 15 September 2020

International experience in the development of patient-derived xenograft models of diffuse intrinsic pontine glioma

artículo científico publicado en 2018

Investigating intracranial tumour growth patterns with multiparametric MRI incorporating Gd-DTPA and USPIO-enhanced imaging

artículo científico publicado en 2016

Investigating the Contribution of Collagen to the Tumor Biomechanical Phenotype with Noninvasive Magnetic Resonance Elastography

artículo científico publicado en 2019

Lactate and choline metabolites detected in vitro by nuclear magnetic resonance spectroscopy are potential metabolic biomarkers for PI3K inhibition in pediatric glioblastoma

artículo científico publicado en 2014

Loss of 5'-Methylthioadenosine Phosphorylase (MTAP) is Frequent in High-Grade Gliomas; Nevertheless, it is Not Associated with Higher Tumor Aggressiveness

artículo científico publicado en 2020

Loss of SPINT2 expression frequently occurs in glioma, leading to increased growth and invasion via MMP2

artículo científico publicado en 2019

Loss of WNK2 expression by promoter gene methylation occurs in adult gliomas and triggers Rac1-mediated tumour cell invasiveness

artículo científico publicado en 2012

Loss of heterozygosity at 2q37 in sporadic Wilms' tumor: putative role for miR-562.

artículo científico publicado en 2009

Loss of heterozygosity at cylindromatosis gene locus, CYLD, in sporadic skin adnexal tumours.

artículo científico publicado en 2001

MGMT-independent temozolomide resistance in pediatric glioblastoma cells associated with a PI3-kinase-mediated HOX/stem cell gene signature

artículo científico publicado en 2010

MIB-1 and p27Kip1 Expression in Nephroblastoma

artículo científico publicado en 2004

MODL-20. A BIOBANK OF ~100 PATIENT-DERIVED MODELS REPRESENTING BIOLOGICAL HETEROGENEITY AND DISTINCT THERAPEUTIC DEPENDENCIES IN PAEDIATRIC HIGH GRADE GLIOMA AND DIPG

artículo científico publicado en 2020

Malignant adenomyoepithelioma of the breast metastasizing to the liver

artículo científico publicado en 2003

Markers of survival and metastatic potential in childhood CNS primitive neuro-ectodermal brain tumours: an integrative genomic analysis

artículo científico publicado en 2012

Mechanistic evaluation of the novel HSP90 inhibitor NVP-AUY922 in adult and pediatric glioblastoma

artículo científico publicado en 2010

Meningeal Hemangiopericytomas and Meningomas: a Comparative Immunohistochemical and Genetic Study

artículo científico publicado en 2015

Mesenchymal transition and PDGFRA amplification/mutation are key distinct oncogenic events in pediatric diffuse intrinsic pontine gliomas

artículo científico publicado en 2012

Microsatellite instability in pediatric high grade glioma is associated with genomic profile and differential target gene inactivation

artículo científico publicado en 2011

Molecular Diagnostic and Prognostic Subtyping of Gliomas in Tunisian Population

artículo científico publicado en 2016

Molecular Profiling of a Rare Rosette-Forming Glioneuronal Tumor Arising in the Spinal Cord

artículo científico publicado en 2015

Molecular and phenotypic characterisation of paediatric glioma cell lines as models for preclinical drug development

artículo científico publicado en 2009

Molecular cytogenetic comparison of apocrine hyperplasia and apocrine carcinoma of the breast

artículo científico publicado en 2001

Molecular cytogenetic identification of subgroups of grade III invasive ductal breast carcinomas with different clinical outcomes

artículo científico publicado en 2004

Molecular profiling pleomorphic lobular carcinomas of the breast: evidence for a common molecular genetic pathway with classic lobular carcinomas

artículo científico publicado en 2008

Molecular profiling reveals frequent gain of MYCN and anaplasia-specific loss of 4q and 14q in wilms tumor

article

Molecular prognostic factors in glioblastoma: state of the art and future challenges

artículo científico publicado en 2013

Molecular, Pathological, Radiological, and Immune Profiling of Non-brainstem Pediatric High-Grade Glioma from the HERBY Phase II Randomized Trial.

artículo científico publicado en 2018

Multifaceted dysregulation of the epidermal growth factor receptor pathway in clear cell sarcoma of the kidney

artículo científico publicado en 2007

Neural Precursor-Derived Pleiotrophin Mediates Subventricular Zone Invasion by Glioma

artículo científico publicado en 2017

New Brain Tumor Entities Emerge from Molecular Classification of CNS-PNETs

artículo científico publicado en 2016

Novel Quinazolinone Inhibitors of ALK2 Flip between Alternate Binding Modes: Structure-Activity Relationship, Structural Characterization, Kinase Profiling, and Cellular Proof of Concept

artículo científico publicado en 2018

Novel oncogenic PDGFRA mutations in pediatric high-grade gliomas

artículo científico publicado en 2013

Oncocytic change in pleomorphic adenoma: molecular evidence in support of an origin in neoplastic cells

artículo científico publicado en 2006

PCM-08IN VIVO MAGNETIC RESONANCE IMAGING IDENTIFIES CLINICAL PHENOTYPES OF PAEDIATRIC GLIOBLASTOMA IN AN ORTHOTOPIC MOUSE XENOGRAFT MODEL.

artículo científico publicado en 2016

PDTM-09. DIFFUSE INTRINSIC PONTINE GLIOMA AND PEDIATRIC GLIOBLASTOMA DERIVED-EXOSOMES HAVE SPECIFIC ONCOGENIC SIGNATURES

PDTM-31. DRUG SCREENING LINKED TO MOLECULAR PROFILING IDENTIFIES NOVEL DEPENDENCIES IN PATIENT-DERIVED PRIMARY CULTURES OF PAEDIATRIC HIGH GRADE GLIOMA AND DIPG

article by Alan Mackay et al published 5 November 2018 in Neuro-Oncology

PDTM-33. ATRX LOSS CONFERS ENHANCED SENSITIVITY TO COMBINED PARP INHIBITION AND RADIOTHERAPY IN PAEDIATRIC GLIOBLASTOMA MODELS

article by Janat Fazal Salom et al published 5 November 2018 in Neuro-Oncology

PDTM-34. TARGETING H3.3G34R/V RE-WIRING OF THE EPIGENOME IN PAEDIATRIC GLIOBLASTOMA OF CHILDREN AND YOUNG ADULTS

article by Lynn Bjerke et al published 5 November 2018 in Neuro-Oncology

PNR-39DISTINCT GENE FUSIONS SEGREGATE SUB-CLASSES OF CNS-PNETs.

artículo científico publicado en 2016

PPM1D mutations are oncogenic drivers of de novo diffuse midline glioma formation

artículo científico publicado en 2022

PPM1D mutations silence NAPRT gene expression and confer NAMPT inhibitor sensitivity in glioma

scientific article published on 22 August 2019

PTPS-15ATRX LOSS PROMOTES TUMOR GROWTH AND IMPAIRS NON-HOMOLOGOUS END JOINING DNA REPAIR IN GLIOMA.

artículo científico publicado en 2015

Paediatric and adult glioblastoma: multiform (epi)genomic culprits emerge

artículo científico publicado en 2014

Paediatric and adult malignant glioma: close relatives or distant cousins?

artículo científico publicado en 2012

Pediatric and adult glioblastoma radiosensitization induced by PI3K/mTOR inhibition causes early metabolic alterations detected by nuclear magnetic resonance spectroscopy

artículo científico publicado en 2017

Pediatric high-grade glioma: biologically and clinically in need of new thinking

artículo científico publicado en 2016

Pediatric pan-central nervous system tumor analysis of immune-cell infiltration identifies correlates of antitumor immunity

artículo científico publicado en 2020

Perilobar nephrogenic rests are nonobligate molecular genetic precursor lesions of insulin-like growth factor-II-associated Wilms tumors

artículo científico publicado en 2008

Phase II, Open-Label, Randomized, Multicenter Trial (HERBY) of Bevacizumab in Pediatric Patients With Newly Diagnosed High-Grade Glioma.

artículo científico publicado en 2018

Pineoblastoma segregates into molecular sub-groups with distinct clinico-pathologic features: a Rare Brain Tumor Consortium registry study

scientific article published on 09 December 2019

Platelet-derived growth factor beta is a potent inflammatory driver in paediatric high-grade glioma

scientific article published on 10 December 2020

Pleomorphic lobular carcinoma of the breast: role of comprehensive molecular pathology in characterization of an entity

scholarly article by Jorge Reis-Filho et al published 2005 in Journal of Pathology

Polo-like kinase 1 inhibition kills glioblastoma multiforme brain tumor cells in part through loss of SOX2 and delays tumor progression in mice.

artículo científico publicado en 2012

Preclinical evaluation of dipotassium bisperoxo (picolinato) oxovanadate V for the treatment of pediatric low-grade gliomas

artículo científico publicado en 2013

Primary glioblastoma with oligodendroglial differentiation has better clinical outcome but no difference in common biological markers compared with other types of glioblastoma

artículo científico publicado en 2013

Pseudoprogression in children, adolescents and young adults with non-brainstem high grade glioma and diffuse intrinsic pontine glioma

artículo científico publicado en 2016

Quantification of spatial subclonal interactions enhancing the invasive phenotype of pediatric glioma

artículo científico publicado en 2022

RACK7 recognizes H3.3G34R mutation to suppress expression of MHC class II complex components and their delivery pathway in pediatric glioblastoma

scientific article published on 17 July 2020

RADI-04. COMBINED RADIOLOGICAL, PATHOLOGICAL AND MOLECULAR OUTCOME EVALUATION IN NEWLY DIAGNOSED NON-BRAINSTEM PEDIATRIC HIGH-GRADE GLIOMA FROM THE RANDOMIZED, MULTICENTER HERBY PHASE II TRIAL

RADI-05. EVALUATION OF THE IMPLEMENTATION OF THE RANO CRITERIA IN THE HERBY TRIAL OF PEDIATRIC PATIENTS WITH NEWLY DIAGNOSED HIGH-GRADE GLIOMAS.

artículo científico publicado en 2018

RAPD library fingerprinting of bacterial and human DNA: applications in mutation detection.

artículo científico publicado en 2000

Radiation-induced gliomas represent H3-/IDH-wild type pediatric gliomas with recurrent PDGFRA amplification and loss of CDKN2A/B

artículo científico publicado en 2021

Radiological Evaluation of Newly Diagnosed Non-Brainstem Pediatric High-Grade Glioma in the HERBY Phase II Trial

scientific article published on 10 January 2020

Receptor tyrosine kinase genes amplified in glioblastoma exhibit a mutual exclusivity in variable proportions reflective of individual tumor heterogeneity

artículo científico publicado en 2012

Recurrent activating ACVR1 mutations in diffuse intrinsic pontine glioma

artículo científico publicado en 2014

Reduced H3K27me3 and DNA hypomethylation are major drivers of gene expression in K27M mutant pediatric high-grade gliomas

artículo científico publicado en 2013

Role of platelet derived growth factor receptor (PDGFR) over-expression and angiogenesis in ependymoma

artículo científico publicado en 2012

Subtype-specific FBXW7 mutation and MYCN copy number gain in Wilms' tumor.

artículo científico publicado en 2010

TBIO-29. PedcBioPortal, A CANCER DATA VISUALIZATION TOOL FOR INTEGRATIVE PEDIATRIC CANCER ANALYSES

artículo científico publicado en 2018

TR-05ER STRESS INDUCING DRUGS DOWNREGULATES MGMT AND MPG SENSITIZING PEDIATRIC GLIOMA CELL LINES TO TMZ.

artículo científico publicado en 2015

Targeted therapy for BRAFV600E malignant astrocytoma.

artículo científico publicado en 2011

The T-box transcription factor brachyury behaves as a tumor suppressor in gliomas

artículo científico publicado en 2020

The genomic landscape of diffuse intrinsic pontine glioma and pediatric non-brainstem high-grade glioma

artículo científico publicado en 2014

The international diffuse intrinsic pontine glioma registry: an infrastructure to accelerate collaborative research for an orphan disease.

artículo científico publicado en 2017

The long non-coding RNA HOTAIR is transcriptionally activated by HOXA9 and is an independent prognostic marker in patients with malignant glioma.

artículo científico publicado en 2018

The oncolytic virus Delta-24-RGD elicits an antitumor effect in pediatric glioma and DIPG mouse models

artículo científico publicado en 2019

The prognostic role of intragenic copy number breakpoints and identification of novel fusion genes in paediatric high grade glioma

artículo científico publicado en 2014

The ten-year evolutionary trajectory of a highly recurrent paediatric high grade neuroepithelial tumour with MN1:BEND2 fusion

artículo científico publicado en 2018

Transcriptomic and epigenetic profiling of 'diffuse midline gliomas, H3 K27M-mutant' discriminate two subgroups based on the type of histone H3 mutated and not supratentorial or infratentorial location

artículo científico publicado en 2018

Unique genetic and epigenetic mechanisms driving paediatric diffuse high-grade glioma

artículo científico publicado en 2014

Unlocking pathology archives for molecular genetic studies: a reliable method to generate probes for chromogenic and fluorescent in situ hybridization

artículo científico publicado en 2006

Viability screen on pediatric low grade glioma cell lines unveils a novel anti-cancer drug of the steroid biosynthesis inhibitor family

artículo científico publicado en 2012

WHO grade has no prognostic value in the pediatric high-grade glioma included in the HERBY trial

scientific article published on 01 January 2020

YB-1 bridges neural stem cells and brain tumor-initiating cells via its roles in differentiation and cell growth

artículo científico publicado en 2011

c-KIT overexpression, without gene amplification and mutation, in paediatric renal tumours

artículo científico publicado en 2007

cDNA microarray analysis of genes associated with ERBB2 (HER2/neu) overexpression in human mammary luminal epithelial cells

artículo científico publicado en 2003

p53 Loss in MYC-Driven Neuroblastoma Leads to Metabolic Adaptations Supporting Radioresistance.

artículo científico publicado en 2016

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

artículo científico publicado en 2016

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