Lista de obras - Michail Nomikos - Dominio Público Uruguay

ATP interacts with the CPVT mutation-associated central domain of the cardiac ryanodine receptor

artículo científico publicado en 2013

Altered RyR2 regulation by the calmodulin F90L mutation associated with idiopathic ventricular fibrillation and early sudden cardiac death

artículo científico publicado en 2014

Antigen unmasking enhances visualization efficacy of the oocyte activation factor, phospholipase C zeta, in mammalian sperm.

artículo científico publicado en 2016

Arrhythmogenic calmodulin E105A mutation alters cardiac RyR2 regulation leading to cardiac dysfunction in zebrafish

scientific article published on 02 April 2019

Binding of phosphoinositide-specific phospholipase C-zeta (PLC-zeta) to phospholipid membranes: potential role of an unstructured cluster of basic residues

artículo científico publicado en 2007

Ca(2+) dynamics in oocytes from naturally-aged mice

artículo científico publicado en 2016

Chimeras of sperm PLCζ reveal disparate protein domain functions in the generation of intracellular Ca2+ oscillations in mammalian eggs at fertilization

artículo científico publicado en 2013

Construct Validity of an Instrument for Assessment of Reflective Writing-Based Portfolios of Medical Students

scientific article published on 03 June 2020

Distinctive malfunctions of calmodulin mutations associated with heart RyR2-mediated arrhythmic disease

scientific journal article

Divergent effect of mammalian PLCζ in generating Ca²⁺ oscillations in somatic cells compared with eggs

artículo científico publicado en 2011

Essential Role of the EF-hand Domain in Targeting Sperm Phospholipase Cζ to Membrane Phosphatidylinositol 4,5-Bisphosphate (PIP2).

artículo científico publicado en 2015

Expression of sperm PLCζ and clinical outcomes of ICSI-AOA in men affected by globozoospermia due to DPY19L2 deletion.

artículo científico publicado en 2017

Functional disparity between human PAWP and PLCζ in the generation of Ca2+ oscillations for oocyte activation

artículo científico publicado en 2015

Human PLCζ exhibits superior fertilization potency over mouse PLCζ in triggering the Ca(2+) oscillations required for mammalian oocyte activation

artículo científico publicado en 2014

Hypertrophic cardiomyopathy-linked variants of cardiac myosin-binding protein C3 display altered molecular properties and actin interaction

scientific article published on 14 December 2018

Is PAWP the "real" sperm factor?

artículo científico publicado en 2015

Male infertility-linked point mutation reveals a vital binding role for the C2 domain of sperm PLCζ.

artículo científico publicado en 2017

Medical Students' Perspectives on an Assessment of Reflective Portfolios [Response to Letter]

scientific article published on 16 July 2020

Mutations in PLCδ1 associated with hereditary leukonychia display divergent PIP2 hydrolytic function.

artículo científico publicado en 2016

Novel signalling mechanism and clinical applications of sperm-specific PLCζ.

artículo científico

PLCζ causes Ca(2+) oscillations in mouse eggs by targeting intracellular and not plasma membrane PI(4,5)P(2).

artículo científico publicado en 2011

PLCζ or PAWP: revisiting the putative mammalian sperm factor that triggers egg activation and embryogenesis

artículo científico publicado en 2015

Phospholipase C zeta and calcium oscillations at fertilisation: The evidence, applications, and further questions

artículo científico publicado en 2017

Phospholipase C-ζ-induced Ca2+ oscillations cause coincident cytoplasmic movements in human oocytes that failed to fertilize after intracytoplasmic sperm injection

artículo científico publicado en 2012

Phospholipase Cζ binding to PtdIns(4,5)P2 requires the XY-linker region

artículo científico publicado en 2011

Rescue of failed oocyte activation after ICSI in a mouse model of male factor infertility by recombinant phospholipase Cζ

artículo científico publicado en 2015

Sperm PLCζ: from structure to Ca2+ oscillations, egg activation and therapeutic potential.

artículo científico publicado en 2013

Sperm-induced Ca2+ release during egg activation in mammals.

artículo científico publicado en 2014

Sperm-specific post-acrosomal WW-domain binding protein (PAWP) does not cause Ca2+ release in mouse oocytes.

artículo científico publicado en 2014

Starting a new life: sperm PLC-zeta mobilizes the Ca2+ signal that induces egg activation and embryo development: an essential phospholipase C with implications for male infertility.

artículo científico publicado en 2011

Targeting inflammatory components in neuropathic pain: The analgesic effect of thymulin related peptide

scientific article published on 29 November 2018

The dynamics of MAPK inactivation at fertilization in mouse eggs.

artículo científico publicado en 2014

The role and mechanism of action of sperm PLC-zeta in mammalian fertilisation.

artículo científico publicado en 2017

Thermal and chemical denaturation of the BRCT functional module of human 53BP1

scientific article published on 11 May 2011

Thermodynamic study of the BRCT domain of BARD1 and its interaction with the -pSER-X-X-Phe- motif-containing BRIP1 peptide

artículo científico publicado en 2010

Lista de obras de Michail Nomikos

ATP interacts with the CPVT mutation-associated central domain of the cardiac ryanodine receptor

Altered RyR2 regulation by the calmodulin F90L mutation associated with idiopathic ventricular fibrillation and early sudden cardiac death

Antigen unmasking enhances visualization efficacy of the oocyte activation factor, phospholipase C zeta, in mammalian sperm.

Arrhythmogenic calmodulin E105A mutation alters cardiac RyR2 regulation leading to cardiac dysfunction in zebrafish

Binding of phosphoinositide-specific phospholipase C-zeta (PLC-zeta) to phospholipid membranes: potential role of an unstructured cluster of basic residues

Ca(2+) dynamics in oocytes from naturally-aged mice

Chimeras of sperm PLCζ reveal disparate protein domain functions in the generation of intracellular Ca2+ oscillations in mammalian eggs at fertilization

Construct Validity of an Instrument for Assessment of Reflective Writing-Based Portfolios of Medical Students

Distinctive malfunctions of calmodulin mutations associated with heart RyR2-mediated arrhythmic disease

Divergent effect of mammalian PLCζ in generating Ca²⁺ oscillations in somatic cells compared with eggs

Essential Role of the EF-hand Domain in Targeting Sperm Phospholipase Cζ to Membrane Phosphatidylinositol 4,5-Bisphosphate (PIP2).

Expression of sperm PLCζ and clinical outcomes of ICSI-AOA in men affected by globozoospermia due to DPY19L2 deletion.

Functional disparity between human PAWP and PLCζ in the generation of Ca2+ oscillations for oocyte activation

Human PLCζ exhibits superior fertilization potency over mouse PLCζ in triggering the Ca(2+) oscillations required for mammalian oocyte activation

Hypertrophic cardiomyopathy-linked variants of cardiac myosin-binding protein C3 display altered molecular properties and actin interaction

Is PAWP the "real" sperm factor?

Male infertility-linked point mutation reveals a vital binding role for the C2 domain of sperm PLCζ.

Medical Students' Perspectives on an Assessment of Reflective Portfolios [Response to Letter]

Mutations in PLCδ1 associated with hereditary leukonychia display divergent PIP2 hydrolytic function.

Novel signalling mechanism and clinical applications of sperm-specific PLCζ.

PLCζ causes Ca(2+) oscillations in mouse eggs by targeting intracellular and not plasma membrane PI(4,5)P(2).

PLCζ or PAWP: revisiting the putative mammalian sperm factor that triggers egg activation and embryogenesis

Phospholipase C zeta and calcium oscillations at fertilisation: The evidence, applications, and further questions

Phospholipase C-ζ-induced Ca2+ oscillations cause coincident cytoplasmic movements in human oocytes that failed to fertilize after intracytoplasmic sperm injection

Phospholipase Cζ binding to PtdIns(4,5)P2 requires the XY-linker region

Rescue of failed oocyte activation after ICSI in a mouse model of male factor infertility by recombinant phospholipase Cζ

Sperm PLCζ: from structure to Ca2+ oscillations, egg activation and therapeutic potential.

Sperm-induced Ca2+ release during egg activation in mammals.

Sperm-specific post-acrosomal WW-domain binding protein (PAWP) does not cause Ca2+ release in mouse oocytes.

Starting a new life: sperm PLC-zeta mobilizes the Ca2+ signal that induces egg activation and embryo development: an essential phospholipase C with implications for male infertility.

Targeting inflammatory components in neuropathic pain: The analgesic effect of thymulin related peptide

The dynamics of MAPK inactivation at fertilization in mouse eggs.

The role and mechanism of action of sperm PLC-zeta in mammalian fertilisation.

Thermal and chemical denaturation of the BRCT functional module of human 53BP1

Thermodynamic study of the BRCT domain of BARD1 and its interaction with the -pSER-X-X-Phe- motif-containing BRIP1 peptide