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2A and the auxin-based degron system facilitate control of protein levels in Plasmodium falciparum

artículo científico publicado en 2013

3-Hydroxy-N'-arylidenepropanehydrazonamides with Halo-Substituted Phenanthrene Scaffolds Cure P. berghei Infected Mice When Administered Perorally

artículo científico publicado en 2017

8-Aminoquinolines with an Aminoxyalkyl Side Chain Exert in vitro Dual-Stage Antiplasmodial Activity

artículo científico publicado en 2019

A flow cytometry-based workflow for detection and quantification of anti-plasmodial antibodies in vaccinated and naturally exposed individuals

artículo científico publicado en 2012

A phase 2b randomized, controlled trial of the efficacy of the GMZ2 malaria vaccine in African children

artículo científico publicado en 2016

A phase 3 trial of RTS,S/AS01 malaria vaccine in African infants

artículo científico publicado en 2012

A randomized controlled phase Ib trial of the malaria vaccine candidate GMZ2 in African children

artículo científico publicado en 2011

A retinal model of cerebral malaria

artículo científico publicado en 2019

A simplified intravenous artesunate regimen for severe malaria

artículo científico publicado en 2011

A single-dose antihelminthic treatment does not influence immunogenicity of a meningococcal and a cholera vaccine in Gabonese school children

artículo científico publicado en 2016

Alterations of blood coagulation in controlled human malaria infection

artículo científico publicado en 2016

Analysis of polymorphic sites in the promoter of the nitric oxide synthase 2 gene

artículo científico publicado en 2005

Analysis of the Plasmodium falciparum proteasome using Blue Native PAGE and label-free quantitative mass spectrometry

artículo científico publicado en 2012

Antigen-stimulated PBMC transcriptional protective signatures for malaria immunization

scientific article published on 01 May 2020

Antihomotypic affinity maturation improves human B cell responses against a repetitive epitope

artículo científico publicado en 2018

Antimalarial activity of a synthetic endoperoxide (RBx-11160/OZ277) against Plasmodium falciparum isolates from Gabon

artículo científico publicado en 2006

Antimalarial activity of the myxobacterial macrolide chlorotonil a. ⬇️

artículo científico publicado en 2014

Artemether-lumefantrine for the treatment of Plasmodium malariae, Plasmodium ovale, and mixed Plasmodium malaria: A prospective clinical trial assessing species-specific efficacy in Gabon

artículo científico publicado en 2018

Artesunate-clindamycin versus quinine-clindamycin in the treatment of Plasmodium falciparum malaria: a randomized controlled trial

artículo científico publicado en 2005

Assessment of LED fluorescence microscopy for the diagnosis of Plasmodium falciparum infections in Gabon

artículo científico publicado en 2011

Associations Between Helminth Infections, Plasmodium falciparum Parasite Carriage and Antibody Responses to Sexual and Asexual Stage Malarial Antigens.

artículo científico publicado en 2016

Atypical and classical memory B cells produce Plasmodium falciparum neutralizing antibodies.

artículo científico publicado en 2013

Baseline exposure, antibody subclass, and hepatitis B response differentially affect malaria protective immunity following RTS,S/AS01E vaccination in African children

artículo científico publicado en 2018

Bats are rare reservoirs of Staphylococcus aureus complex in Gabon.

artículo científico publicado en 2016

Behavioural and clinical predictors for Loiasis.

artículo científico publicado en 2018

Binding modes of reverse fosmidomycin analogs toward the antimalarial target IspC

artículo científico publicado en 2014

Blood schizontocidal and gametocytocidal activity of 3-hydroxy-N'-arylidenepropanehydrazonamides: a new class of antiplasmodial compounds

artículo científico publicado en 2014

Broad-spectrum antimalarial activity of peptido sulfonyl fluorides, a new class of proteasome inhibitors.

artículo científico publicado en 2013

Capsid-like particles decorated with the SARS-CoV-2 receptor-binding domain elicit strong virus neutralization activity

artículo científico publicado en 2021

Characterisation of a tryptophan-rich Plasmodium falciparum antigen associated with merozoites

artículo científico publicado en 2004

Characterization of Plasmodium infections among inhabitants of rural areas in Gabon

scientific article published on 05 July 2019

Clinical and parasitological characteristics of puerperal malaria

artículo científico publicado en 2005

Clinical development of a VAR2CSA-based placental malaria vaccine PAMVAC: Quantifying vaccine antigen-specific memory B & T cell activity in Beninese primigravidae

artículo científico publicado en 2017

Clonal selection drives protective memory B cell responses in controlled human malaria infection

artículo científico publicado en 2018

Comprehensive study of proteasome inhibitors against Plasmodium falciparum laboratory strains and field isolates from Gabon

artículo científico publicado en 2008

Concentration and avidity of antibodies to different circumsporozoite epitopes correlate with RTS,S/AS01E malaria vaccine efficacy

artículo científico publicado en 2019

Controlled Human Malaria Infection of Healthy Adults With Lifelong Malaria Exposure to Assess Safety, Immunogenicity, and Efficacy of the Asexual Blood Stage Malaria Vaccine Candidate GMZ2

scientific article published on 01 September 2019

Controlled human malaria infection by intramuscular and direct venous inoculation of cryopreserved Plasmodium falciparum sporozoites in malaria-naïve volunteers: effect of injection volume and dose on infectivity rates

artículo científico publicado en 2015

Controlled human malaria infection with Plasmodium falciparum demonstrates impact of naturally acquired immunity on virulence gene expression

scientific article published on 11 July 2019

Controlled human malaria infections using aseptic, purified cryopreserved Plasmodium falciparum sporozoites administered by needle and syringe

artículo científico publicado en 2014

Cord blood dendritic cell subsets in African newborns exposed to Plasmodium falciparum in utero

artículo científico publicado en 2006

Correlating efficacy and immunogenicity in malaria vaccine trials

artículo científico publicado en 2018

Cytokine and chemokine profile of the innate and adaptive immune response of Schistosoma haematobium and Plasmodium falciparum single and co-infected school-aged children from an endemic area of Lambaréné, Gabon

artículo científico publicado en 2015

DNA recovery from archived RDTs for genetic characterization of Plasmodium falciparum in a routine setting in Lambaréné, Gabon

scientific article published on 02 October 2019

DSM265 for Plasmodium falciparum chemoprophylaxis: a randomised, double blinded, phase 1 trial with controlled human malaria infection

artículo científico publicado en 2017

Delayed hemolysis after treatment with parenteral artesunate in African children with severe malaria--a double-center prospective study

artículo científico publicado en 2013

Demography, maternal health and the epidemiology of malaria and other major infectious diseases in the rural department Tsamba-Magotsi, Ngounie Province, in central African Gabon

artículo científico publicado en 2017

Design and Synthesis of Novel Anti-Plasmodial Histone Deacetylase Inhibitors Containing an Alkoxyamide Connecting Unit.

artículo científico publicado en 2017

Development and evaluation of a multiplex screening assay for Plasmodium falciparum exposure

artículo científico publicado en 2012

Direct venous inoculation of Plasmodium falciparum sporozoites for controlled human malaria infection: a dose-finding trial in two centres

artículo científico publicado en 2015

Discovery of HDAC inhibitors with potent activity against multiple malaria parasite life cycle stages

artículo científico publicado en 2014

Distinct TH1 and TH2 cellular responses associated with malaria protection and risk in RTS,S/AS01E vaccinees

artículo científico publicado en 2017

Effect of Antihelminthic Treatment on Vaccine Immunogenicity to a Seasonal Influenza Vaccine in Primary School Children in Gabon: A Randomized Placebo-Controlled Trial

artículo científico publicado en 2015

Effect of IL-15 on IgG versus IgE antibody-secreting cells in vitro

artículo científico publicado en 2011

Effect of fluorescent dyes on in vitro-differentiated, late-stage Plasmodium falciparum gametocytes

artículo científico publicado en 2014

Efficacy and Safety of Fosmidomycin-Piperaquine as Nonartemisinin-Based Combination Therapy for Uncomplicated Falciparum Malaria: A Single-Arm, Age De-escalation Proof-of-Concept Study in Gabon

artículo científico publicado en 2018

Efficacy, T cell activation and antibody responses in accelerated Plasmodium falciparum sporozoite chemoprophylaxis vaccine regimens

artículo científico publicado en 2022

Emerging drugs for malaria

artículo científico

Erratum to: Severe malaria in children leads to a significant impairment of transitory otoacoustic emissions - a prospective multicenter cohort study

artículo científico publicado en 2016

Experimental infection of human volunteers

Experimental infections in humans-historical and ethical reflections

scientific article published on 15 November 2019

Ferroquine and artesunate in African adults and children with Plasmodium falciparum malaria: a phase 2, multicentre, randomised, double-blind, dose-ranging, non-inferiority study

artículo científico publicado en 2015

First results of phase 3 trial of RTS,S/AS01 malaria vaccine in African children

artículo científico publicado en 2011

First-in-human, Randomized, Double-blind Clinical Trial of Differentially Adjuvanted PAMVAC, A Vaccine Candidate to Prevent Pregnancy-associated Malaria

scientific article published on 01 October 2019

Fixed-dose pyronaridine-artesunate combination for treatment of uncomplicated falciparum malaria in pediatric patients in Gabon

artículo científico publicado en 2008

Fosmidomycin as an antimalarial drug: a meta-analysis of clinical trials

artículo científico

Growth Rate of Plasmodium falciparum: Analysis of Parasite Growth Data From Malaria Volunteer Infection Studies

scientific article published on 01 March 2020

Haematological and biochemical reference intervals for infants and children in Gabon

artículo científico publicado en 2010

Hemolysis is associated with low reticulocyte production index and predicts blood transfusion in severe malarial anemia

artículo científico publicado en 2010

Hemozoin (malarial pigment) inhibits differentiation and maturation of human monocyte-derived dendritic cells: a peroxisome proliferator-activated receptor-gamma-mediated effect

artículo científico publicado en 2004

High-Throughput tri-colour flow cytometry technique to assess Plasmodium falciparum parasitaemia in bioassays

artículo científico publicado en 2014

History and perspectives of medical research at the Albert Schweitzer Hospital in Lambaréné, Gabon

artículo científico publicado en 2007

Human Plasmodium vivax diversity, population structure and evolutionary origin

artículo científico publicado en 2020

Human collectin-11 (COLEC11) and its synergic genetic interaction with MASP2 are associated with the pathophysiology of Chagas Disease

article

Humoral immune response to Plasmodium falciparum vaccine candidate GMZ2 and its components in populations naturally exposed to seasonal malaria in Ethiopia

artículo científico publicado en 2013

Hyperparasitemia and Blood Exchange Transfusion for Treatment of Children with Falciparum Malaria ⬇️

artículo científico publicado el 1 de abril de 1998

Immunological tests to diagnose active tuberculosis

artículo científico publicado en 2009

Impact of Sickle Cell Trait and Naturally Acquired Immunity on Uncomplicated Malaria after Controlled Human Malaria Infection in Adults in Gabon

artículo científico publicado en 2017

In vitro activity of ferroquine (SAR97193) is independent of chloroquine resistance in Plasmodium falciparum.

artículo científico publicado en 2006

In vitro activity of fluorescent dyes against asexual blood stages of Plasmodium falciparum.

artículo científico publicado en 2012

In vitro activity of mirincamycin (U24729A) against Plasmodium falciparum isolates from Gabon

artículo científico publicado en 2009

In vitro activity of new artemisinin derivatives against Plasmodium falciparum clinical isolates from Gabon

artículo científico publicado en 2011

In vitro activity of pyronaridine against Plasmodium falciparum and comparative evaluation of anti-malarial drug susceptibility assays

artículo científico publicado en 2009

In vitro activity of tigecycline in Plasmodium falciparum culture-adapted strains and clinical isolates from Gabon

artículo científico publicado en 2010

In vitro growth of Plasmodium falciparum in neonatal blood

artículo científico publicado en 2014

Increase in annexin V-positive B cells expressing LILRB1/ILT2/CD85j in malaria.

artículo científico publicado en 2006

Induction of Plasmodium falciparum-specific CD4+ T cells and memory B cells in Gabonese children vaccinated with RTS,S/AS01(E) and RTS,S/AS02(D)

artículo científico publicado en 2011

Intramuscular Artesunate for Severe Malaria in African Children: A Multicenter Randomized Controlled Trial

artículo científico publicado en 2016

IspC as target for antiinfective drug discovery: synthesis, enantiomeric separation, and structural biology of fosmidomycin thia isosters

artículo científico publicado en 2013

Ivermectin Impairs the Development of Sexual and Asexual Stages of Plasmodium falciparum In Vitro

scientific article published on 25 July 2019

Lessons from a modern review of the smallpox eradication files

artículo científico publicado en 2015

Life-span of in vitro differentiated Plasmodium falciparum gametocytes

artículo científico

Limit of blank and limit of detection of Plasmodium falciparum thick blood smear microscopy in a routine setting in Central Africa

artículo científico publicado en 2014

Loa loa-does it deserve to be neglected?

artículo científico publicado en 2013

Lymphotoxin and lipopolysaccharide induce NF-kappaB-p52 generation by a co-translational mechanism

artículo científico publicado en 2003

Malaria therapy in the era of chloroquine resistance

artículo científico publicado el 8 de mayo de 1998

Malarial parasites vs. antimalarials: never-ending rumble in the jungle

artículo científico publicado en 2006

Mitochondrial localization of the threonine peptidase PfHslV, a ClpQ ortholog in Plasmodium falciparum

artículo científico publicado en 2010

Mosquito Passage Dramatically Changes var Gene Expression in Controlled Human Plasmodium falciparum Infections

artículo científico publicado en 2016

Natural Parasite Exposure Induces Protective Human Anti-Malarial Antibodies

artículo científico publicado en 2017

Natural infection of Plasmodium brasilianum in humans: Man and monkey share quartan malaria parasites in the Venezuelan Amazon

artículo científico publicado en 2015

Naturally acquired immune responses to malaria vaccine candidate antigens MSP3 and GLURP in Guahibo and Piaroa indigenous communities of the Venezuelan Amazon

artículo científico publicado en 2012

Neutrophil extracellular traps drive inflammatory pathogenesis in malaria

scientific article published on 01 October 2019

New medicines for malaria

artículo científico publicado en 2010

New method to quantify erythrophagocytosis by autologous monocytes.

artículo científico publicado en 2007

Notch ligands Delta-like1, Delta-like4 and Jagged1 differentially regulate activation of peripheral T helper cells.

artículo científico publicado en 2005

Novel approaches in antimalarial drug discovery

artículo científico

Novel approaches to whole sporozoite vaccination against malaria.

artículo científico

Novel reverse thia-analogs of fosmidomycin: Synthesis and antiplasmodial activity

scientific article published on 22 July 2019

Nycteria and Polychromophilus parasite infections of bats in Central Gabon

artículo científico publicado en 2018

Parasites and pregnancy

artículo científico publicado en 2007

Phase 1 Trials of rVSV Ebola Vaccine in Africa and Europe

artículo científico publicado en 2016

Plasmodia express two threonine-peptidase complexes during asexual development

article

Plasmodium vivax malaria in Duffy-negative individuals from Ethiopia

artículo científico publicado en 2013

Polymorphism in promoter region of inducible nitric oxide synthase gene and protection against malaria ⬇️

artículo científico publicado el 24 de enero de 1998

Prodrugs of reverse fosmidomycin analogues

artículo científico publicado en 2015

Progress with PfSPZ Vaccine, a radiation attenuated Plasmodium falciparum sporozoite vaccine

artículo científico publicado en 2014

Progress with Plasmodium falciparum sporozoite (PfSPZ)-based malaria vaccines

scientific article published on 12 October 2015

Promoter variants of the human mannose-binding lectin gene show different binding.

artículo científico

Prospective Clinical and Molecular Evaluation of Potential Plasmodium ovale curtisi and wallikeri Relapses in a High-transmission Setting

artículo científico publicado en 2019

Prospective evaluation of artemether-lumefantrine for the treatment of non-falciparum and mixed-species malaria in Gabon

artículo científico publicado en 2012

Randomized, controlled, assessor-blind clinical trial to assess the efficacy of single- versus repeated-dose albendazole to treat ascaris lumbricoides, trichuris trichiura, and hookworm infection

artículo científico publicado en 2014

Rare PfCSP C-terminal antibodies induced by live sporozoite vaccination are ineffective against malaria infection

artículo científico publicado en 2017

Real-time measurement of Plasmodium falciparum-infected erythrocyte cytoadhesion with a quartz crystal microbalance.

artículo científico publicado en 2016

Recognition of Plasmodium falciparum mature gametocyte-infected erythrocytes by antibodies of semi-immune adults and malaria-exposed children from Gabon

artículo científico publicado en 2017

Reduced CD3/TCR complex expression leads to immunosuppression during Plasmodium falciparum malaria

artículo científico publicado en 2008

Reduced antibody responses against Plasmodium falciparum vaccine candidate antigens in the presence of Trichuris trichiura

artículo científico publicado en 2012

Safety and efficacy of the choline analogue SAR97276 for malaria treatment: results of two phase 2, open-label, multicenter trials in African patients

artículo científico publicado en 2017

Safety and immunogenicity of GMZ2 - a MSP3-GLURP fusion protein malaria vaccine candidate

artículo científico publicado en 2009

Safety and immunogenicity of rVSVΔG-ZEBOV-GP Ebola vaccine in adults and children in Lambaréné, Gabon: A phase I randomised trial

artículo científico publicado en 2017

Safety and immunogenicity of the malaria vaccine candidate GMZ2 in malaria-exposed, adult individuals from Lambaréné, Gabon

artículo científico publicado en 2010

Schistosoma co-infection protects against brain pathology but does not prevent severe disease and death in a murine model of cerebral malaria

artículo científico publicado en 2010

Selection of a trioxaquine as an antimalarial drug candidate

artículo científico publicado en 2008

Severe malaria in children leads to a significant impairment of transitory otoacoustic emissions--a prospective multicenter cohort study

artículo científico publicado en 2015

Species and genotype diversity of Plasmodium in malaria patients from Gabon analysed by next generation sequencing.

artículo científico publicado en 2017

Sporozoite Route of Infection Influences In Vitro var Gene Transcription of Plasmodium falciparum Parasites From Controlled Human Infections.

artículo científico publicado en 2016

Sterile protection against human malaria by chemoattenuated PfSPZ vaccine

artículo científico publicado en 2017

Synthesis and study of cytotoxic activity of 1,2,4-trioxane- and egonol-derived hybrid molecules against Plasmodium falciparum and multidrug-resistant human leukemia cells.

artículo científico publicado en 2014

The GMZ2 malaria vaccine: from concept to efficacy in humans.

artículo científico publicado en 2017

The Influence of Sub-Unit Composition and Expression System on the Functional Antibody Response in the Development of a VAR2CSA Based Plasmodium falciparum Placental Malaria Vaccine

artículo científico publicado en 2015

The dual role of tumor necrosis factor (TNF) during a malarial attack

artículo científico publicado en 1997

The effect of immunization schedule with the malaria vaccine candidate RTS,S/AS01E on protective efficacy and anti-circumsporozoite protein antibody avidity in African infants

artículo científico publicado en 2015

The frontline of controlled human malaria infections: A report from the controlled human infection models Workshop in Leiden University Medical Centre 5 May 2016.

artículo científico publicado en 2017

The malaria vaccine candidate GMZ2 elicits functional antibodies in individuals from malaria endemic and non-endemic areas

artículo científico publicado en 2013

Threonine peptidases as drug targets against malaria

artículo científico publicado en 2011

Transcriptome profiling reveals functional variation in Plasmodium falciparum parasites from controlled human malaria infection studies

artículo científico publicado en 2019

Use of Capillary Blood Samples Leads to Higher Parasitemia Estimates and Higher Diagnostic Sensitivity of Microscopic and Molecular Diagnostics of Malaria than Venous Blood Samples

article

Validity and reliability of methods to microscopically detect and quantify malaria parasitaemia

scholarly article by Johannes Mischlinger et al published 28 June 2018 in Tropical Medicine and International Health

Workshop report: Malaria vaccine development in Europe--preparing for the future.

artículo científico

α-Substituted β-oxa isosteres of fosmidomycin: synthesis and biological evaluation.

artículo científico publicado en 2012

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