Lista de obras -

2-Arylthiomorpholine derivatives as potent and selective monoamine oxidase B inhibitors

artículo científico publicado en 2010

A new class of powerful inhibitors of monamine oxidase A

artículo científico publicado en 1990

A perspective on multi-target drug discovery and design for complex diseases

artículo científico publicado en 2018

A snapshot of carnitine acetyltransferase

artículo científico publicado en 2003

A stable tyrosyl radical in monoamine oxidase A.

artículo científico publicado en 2004

ASS234, As a New Multi-Target Directed Propargylamine for Alzheimer's Disease Therapy.

artículo científico publicado en 2016

Alteration in spectral properties on ligand binding reveals flexibility in monoamine oxidase.

artículo científico publicado en 2005

An improved approach to steady-state analysis of monoamine oxidases

artículo científico publicado en 2011

Assessment of Enzyme Inhibition: A Review with Examples from the Development of Monoamine Oxidase and Cholinesterase Inhibitory Drugs

artículo científico publicado en 2017

Carnitine acyltransferases and their influence on CoA pools in health and disease

artículo científico publicado en 2004

Carnitine palmitoyltransferase and acyl-coA binding protein: two more players in the membrane phospholipid fatty acid turnover of human red cells? ⬇️

artículo científico publicado el 1 de agosto de 1997

Carnitine, mitochondrial function and therapy

artículo científico publicado en 2009

Characteristics of L-carnitine transport by lactating rat mammary tissue ⬇️

artículo científico publicado el 31 de julio de 1998

Characterization of the covalently bound anionic flavin radical in monoamine oxidase a by electron paramagnetic resonance.

artículo científico publicado en 2007

Comparative Analysis of the Neurochemical Profile and MAO Inhibition Properties of N-(Furan-2-ylmethyl)-N-methylprop-2-yn-1-amine.

artículo científico publicado en 2016

Computational Comparison of Imidazoline Association with the I2 Binding Site in Human Monoamine Oxidases

Conformational changes in monoamine oxidase A in response to ligand binding or reduction

artículo científico publicado en 2004

Correction to Computational Comparison of Imidazoline Association with the I2 Binding Site in Human Monoamine Oxidases

scholarly article published in Journal of Chemical Information and Modeling

Deficiencies of NADH and succinate dehydrogenases in degenerative diseases and myopathies ⬇️

artículo científico publicado el 24 de mayo de 1995

Design, Synthesis and in vitro Evaluation of Indolotacrine Analogues as Multitarget-Directed Ligands for the Treatment of Alzheimer's Disease.

artículo científico publicado en 2015

Design, synthesis, molecular modelling and in vitro screening of monoamine oxidase inhibitory activities of novel quinazolyl hydrazine derivatives

scientific article published on 22 April 2020

Dietary inhibitors of monoamine oxidase A ⬇️

artículo científico publicado el 29 de diciembre de 2010

Editorial: Structure-Based Drug Design for Diagnosis and Treatment of Neurological Diseases.

artículo científico publicado en 2017

Electron carriers and energy conservation in mitochondrial respiration

artículo científico publicado en 2019

Evidence for a Cyanine Link Between Propargylamine Drugs and Monoamine Oxidase Clarifies the Inactivation Mechanism.

artículo científico publicado en 2018

Evidence that the inhibition sites of the neurotoxic amine 1-methyl-4-phenylpyridinium (MPP+) and of the respiratory chain inhibitor piericidin A are the same

artículo científico publicado en 1991

Exploring the structural basis of the selective inhibition of monoamine oxidase A by dicarbonitrile aminoheterocycles: role of Asn181 and Ile335 validated by spectroscopic and computational studies.

artículo científico publicado en 2013

Expression of a sodium-dependent L-carnitine transporter in lactating rat mammary tissue ⬇️

artículo científico publicado el 1 de mayo de 1998

Identification of 4-substituted 1,2,3-triazoles as novel oxazolidinone antibacterial agents with reduced activity against monoamine oxidase A.

artículo científico publicado en 2005

Inhibition of NADH oxidation by pyridine derivatives

artículo científico publicado en 1987

Inhibitor design for monoamine oxidases

artículo científico publicado en 2013

Inhibitors alter the spectrum and redox properties of monoamine oxidase A.

artículo científico publicado en 2002

Interactions of D-amphetamine with the active site of monoamine oxidase-A.

artículo científico publicado en 2003

Interactions of imidazoline ligands with the active site of purified monoamine oxidase A

artículo científico publicado en 2007

Interdisciplinary Chemical Approaches for Neuropathology

artículo científico publicado en 2014

Key Targets for Multi-Target Ligands Designed to Combat Neurodegeneration

artículo científico publicado en 2016

Kinetic and structural analysis of the irreversible inhibition of human monoamine oxidases by ASS234, a multi-target compound designed for use in Alzheimer's disease

artículo científico publicado en 2014

Kinetics, mechanism, and inhibition of monoamine oxidase.

artículo científico publicado en 2018

Live cell interactome of the human voltage dependent anion channel 3 (VDAC3) revealed in HeLa cells by affinity purification tag technique

artículo científico publicado en 2014

MAO and aggression

artículo científico publicado en 2016

Malonyl-CoA inhibition of peroxisomal carnitine octanoyltransferase ⬇️

artículo científico publicado el 1 de septiembre de 1992

Mechanism-based inactivation of monoamine oxidases A and B by tetrahydropyridines and dihydropyridines

artículo científico publicado en 1990

Molecular aspects of monoamine oxidase B.

artículo científico publicado en 2016

Monoamine Oxidase Contains a Redox-active Disulfide ⬇️

artículo científico publicado el 5 de junio de 1998

Monoamine Oxidases: The Biochemistry of the Proteins As Targets in Medicinal Chemistry and Drug Discovery

artículo científico publicado el 1 de enero de 2012

Monoamine oxidase A inhibitory potency and flavin perturbation are influenced by different aspects of pirlindole inhibitor structure

artículo científico publicado en 2003

Multi-Target Directed Donepezil-Like Ligands for Alzheimer's Disease

artículo científico publicado en 2016

Multipotente Liganden mit kombinierter Cholinesterase- und Monoaminooxidase-Inhibition sowie Histamin-H3 R-Antagonismus bei neurodegenerativen Erkrankungen

Multitarget-Directed Ligands Combining Cholinesterase and Monoamine Oxidase Inhibition with Histamine H3 R Antagonism for Neurodegenerative Diseases.

artículo científico publicado en 2017

Mutation of surface cysteine 374 to alanine in monoamine oxidase A alters substrate turnover and inactivation by cyclopropylamines

artículo científico publicado en 2005

N-Methyl-N-((1-methyl-5-(3-(1-(2-methylbenzyl)piperidin-4-yl)propoxy)-1H-indol-2-yl)methyl)prop-2-yn-1-amine, a new cholinesterase and monoamine oxidase dual inhibitor.

artículo científico publicado en 2014

Neurobiology and neuropharmacology of monoaminergic systems

artículo científico publicado en 2017

Neuroprotective actions of leptin facilitated through balancing mitochondrial morphology and improving mitochondrial function

artículo científico publicado en 2020

On the formation and nature of the imidazoline I2 binding site on human monoamine oxidase-B.

artículo científico publicado en 2010

One for All? Hitting Multiple Alzheimer's Disease Targets with One Drug

artículo científico publicado en 2016

Orientation of oxazolidinones in the active site of monoamine oxidase

artículo científico publicado en 2005

Oxidation of analogs of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine by monoamine oxidases A and B and the inhibition of monoamine oxidases by the oxidation products

scientific article published on 01 December 1989

Parameters for Irreversible Inactivation of Monoamine Oxidase

scientific article published on 13 December 2020

Predicting targets of compounds against neurological diseases using cheminformatic methodology.

artículo científico publicado en 2014

Reaction site of carboxanilides and of thenoyltrifluoroacetone in complex II.

artículo científico publicado en 1981

Regulation of Carnitine Acyltransferase Synthesis in Lean and Obese Zucker Rats by Dehydroepiandrosterone and Clofibrate ⬇️

artículo científico publicado el 1 de abril de 1991

Relation of superoxide generation and lipid peroxidation to the inhibition of NADH-Q oxidoreductase by rotenone, piericidin A, and MPP+

artículo científico publicado el 30 de noviembre de 1992

Relationship of the oxidation state of the iron sulfur cluster of aconitase to activity and substrate binding ⬇️

artículo científico publicado el 22 de diciembre de 1981

Resonance Raman studies of beef heart aconitase and a bacterial hydrogenase ⬇️

artículo científico publicado el 10 de noviembre de 1983

Structural dependence of the inhibition of mitochondrial respiration and of NADH oxidase by 1-methyl-4-phenylpyridinium (MPP+) analogs and their energized accumulation by mitochondria

artículo científico publicado en 1989

Studies on the characterization of the inhibitory mechanism of 4'-alkylated 1-methyl-4-phenylpyridinium and phenylpyridine analogues in mitochondria and electron transport particles

artículo científico publicado en 1994

Substrates but Not Inhibitors Alter the Redox Potentials of Monoamine Oxidases ⬇️

artículo científico publicado el 1 de octubre de 2001

Synthesis and evaluation of frentizole-based indolyl thiourea analogues as MAO/ABAD inhibitors for Alzheimer's disease treatment

artículo científico publicado en 2016

Synthesis, biological evaluation, and molecular modeling of nitrile-containing compounds: Exploring multiple activities as anti-Alzheimer agents

artículo científico publicado en 2019

TCP-FA4: a derivative of tranylcypromine showing improved blood-brain permeability.

artículo científico publicado en 2009

Tacrine-allyl/propargylcysteine–benzothiazole trihybrids as potential anti-Alzheimer's drug candidates

scholarly article in RSC Advances, vol. 6 no. 58, 2016

The Role of Carnitine, the Carnitine Acyltransferases and the Carnitine-Exchange System ⬇️

artículo científico publicado el 1 de enero de 1978

The mechanism of fatty acid uptake by heart mitochondria: an acylcarnitine-carnitine exchange

artículo científico publicado el 1 de junio de 1975

Updating neuropathology and neuropharmacology of monoaminergic systems

artículo científico publicado en 2016

Uptake of the neurotoxin 1-methyl-4-phenylpyridine (MPP+) by mitochondria and its relation to the inhibition of the mitochondrial oxidation of NAD+-linked substrates by MPP+

artículo científico publicado en 1986

cis-Cyclopropylamines as mechanism-based inhibitors of monoamine oxidases

artículo científico publicado en 2015

Lista de obras de

2-Arylthiomorpholine derivatives as potent and selective monoamine oxidase B inhibitors

A new class of powerful inhibitors of monamine oxidase A

A perspective on multi-target drug discovery and design for complex diseases

A snapshot of carnitine acetyltransferase

A stable tyrosyl radical in monoamine oxidase A.

ASS234, As a New Multi-Target Directed Propargylamine for Alzheimer's Disease Therapy.

Alteration in spectral properties on ligand binding reveals flexibility in monoamine oxidase.

An improved approach to steady-state analysis of monoamine oxidases

Assessment of Enzyme Inhibition: A Review with Examples from the Development of Monoamine Oxidase and Cholinesterase Inhibitory Drugs

Carnitine acyltransferases and their influence on CoA pools in health and disease

Carnitine palmitoyltransferase and acyl-coA binding protein: two more players in the membrane phospholipid fatty acid turnover of human red cells? ⬇️

Carnitine, mitochondrial function and therapy

Characteristics of L-carnitine transport by lactating rat mammary tissue ⬇️

Characterization of the covalently bound anionic flavin radical in monoamine oxidase a by electron paramagnetic resonance.

Comparative Analysis of the Neurochemical Profile and MAO Inhibition Properties of N-(Furan-2-ylmethyl)-N-methylprop-2-yn-1-amine.

Computational Comparison of Imidazoline Association with the I2 Binding Site in Human Monoamine Oxidases

Conformational changes in monoamine oxidase A in response to ligand binding or reduction

Correction to Computational Comparison of Imidazoline Association with the I2 Binding Site in Human Monoamine Oxidases

Deficiencies of NADH and succinate dehydrogenases in degenerative diseases and myopathies ⬇️

Design, Synthesis and in vitro Evaluation of Indolotacrine Analogues as Multitarget-Directed Ligands for the Treatment of Alzheimer's Disease.

Design, synthesis, molecular modelling and in vitro screening of monoamine oxidase inhibitory activities of novel quinazolyl hydrazine derivatives

Dietary inhibitors of monoamine oxidase A ⬇️

Editorial: Structure-Based Drug Design for Diagnosis and Treatment of Neurological Diseases.

Electron carriers and energy conservation in mitochondrial respiration

Evidence for a Cyanine Link Between Propargylamine Drugs and Monoamine Oxidase Clarifies the Inactivation Mechanism.

Evidence that the inhibition sites of the neurotoxic amine 1-methyl-4-phenylpyridinium (MPP+) and of the respiratory chain inhibitor piericidin A are the same

Exploring the structural basis of the selective inhibition of monoamine oxidase A by dicarbonitrile aminoheterocycles: role of Asn181 and Ile335 validated by spectroscopic and computational studies.

Expression of a sodium-dependent L-carnitine transporter in lactating rat mammary tissue ⬇️

Identification of 4-substituted 1,2,3-triazoles as novel oxazolidinone antibacterial agents with reduced activity against monoamine oxidase A.

Inhibition of NADH oxidation by pyridine derivatives

Inhibitor design for monoamine oxidases

Inhibitors alter the spectrum and redox properties of monoamine oxidase A.

Interactions of D-amphetamine with the active site of monoamine oxidase-A.

Interactions of imidazoline ligands with the active site of purified monoamine oxidase A

Interdisciplinary Chemical Approaches for Neuropathology

Key Targets for Multi-Target Ligands Designed to Combat Neurodegeneration

Kinetic and structural analysis of the irreversible inhibition of human monoamine oxidases by ASS234, a multi-target compound designed for use in Alzheimer's disease

Kinetics, mechanism, and inhibition of monoamine oxidase.

Live cell interactome of the human voltage dependent anion channel 3 (VDAC3) revealed in HeLa cells by affinity purification tag technique

MAO and aggression

Malonyl-CoA inhibition of peroxisomal carnitine octanoyltransferase ⬇️

Mechanism-based inactivation of monoamine oxidases A and B by tetrahydropyridines and dihydropyridines

Molecular aspects of monoamine oxidase B.

Monoamine Oxidase Contains a Redox-active Disulfide ⬇️

Monoamine Oxidases: The Biochemistry of the Proteins As Targets in Medicinal Chemistry and Drug Discovery

Monoamine oxidase A inhibitory potency and flavin perturbation are influenced by different aspects of pirlindole inhibitor structure

Multi-Target Directed Donepezil-Like Ligands for Alzheimer's Disease

Multipotente Liganden mit kombinierter Cholinesterase- und Monoaminooxidase-Inhibition sowie Histamin-H3 R-Antagonismus bei neurodegenerativen Erkrankungen

Multitarget-Directed Ligands Combining Cholinesterase and Monoamine Oxidase Inhibition with Histamine H3 R Antagonism for Neurodegenerative Diseases.

Mutation of surface cysteine 374 to alanine in monoamine oxidase A alters substrate turnover and inactivation by cyclopropylamines

N-Methyl-N-((1-methyl-5-(3-(1-(2-methylbenzyl)piperidin-4-yl)propoxy)-1H-indol-2-yl)methyl)prop-2-yn-1-amine, a new cholinesterase and monoamine oxidase dual inhibitor.

Neurobiology and neuropharmacology of monoaminergic systems

Neuroprotective actions of leptin facilitated through balancing mitochondrial morphology and improving mitochondrial function

On the formation and nature of the imidazoline I2 binding site on human monoamine oxidase-B.

One for All? Hitting Multiple Alzheimer's Disease Targets with One Drug

Orientation of oxazolidinones in the active site of monoamine oxidase

Oxidation of analogs of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine by monoamine oxidases A and B and the inhibition of monoamine oxidases by the oxidation products

Parameters for Irreversible Inactivation of Monoamine Oxidase

Predicting targets of compounds against neurological diseases using cheminformatic methodology.

Reaction site of carboxanilides and of thenoyltrifluoroacetone in complex II.

Regulation of Carnitine Acyltransferase Synthesis in Lean and Obese Zucker Rats by Dehydroepiandrosterone and Clofibrate ⬇️

Relation of superoxide generation and lipid peroxidation to the inhibition of NADH-Q oxidoreductase by rotenone, piericidin A, and MPP+

Relationship of the oxidation state of the iron sulfur cluster of aconitase to activity and substrate binding ⬇️

Resonance Raman studies of beef heart aconitase and a bacterial hydrogenase ⬇️

Structural dependence of the inhibition of mitochondrial respiration and of NADH oxidase by 1-methyl-4-phenylpyridinium (MPP+) analogs and their energized accumulation by mitochondria

Studies on the characterization of the inhibitory mechanism of 4'-alkylated 1-methyl-4-phenylpyridinium and phenylpyridine analogues in mitochondria and electron transport particles

Substrates but Not Inhibitors Alter the Redox Potentials of Monoamine Oxidases ⬇️

Synthesis and evaluation of frentizole-based indolyl thiourea analogues as MAO/ABAD inhibitors for Alzheimer's disease treatment

Synthesis, biological evaluation, and molecular modeling of nitrile-containing compounds: Exploring multiple activities as anti-Alzheimer agents

TCP-FA4: a derivative of tranylcypromine showing improved blood-brain permeability.

Tacrine-allyl/propargylcysteine–benzothiazole trihybrids as potential anti-Alzheimer's drug candidates

The Role of Carnitine, the Carnitine Acyltransferases and the Carnitine-Exchange System ⬇️

The mechanism of fatty acid uptake by heart mitochondria: an acylcarnitine-carnitine exchange

Updating neuropathology and neuropharmacology of monoaminergic systems

Uptake of the neurotoxin 1-methyl-4-phenylpyridine (MPP+) by mitochondria and its relation to the inhibition of the mitochondrial oxidation of NAD+-linked substrates by MPP+

cis-Cyclopropylamines as mechanism-based inhibitors of monoamine oxidases