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A Population Pharmacokinetic and Exposure-Response Model of Golimumab for Targeting Endoscopic Remission in Patients With Ulcerative Colitis

artículo científico publicado en 2020

A model of the ventilatory depressant potency of remifentanil in the non-steady state

artículo científico publicado en 2003

A new model for drug interactions and optimal drug dosing.

artículo científico publicado en 2005

Amiodarone in a newborn with ventricular tachycardia and an intracardiac tumor: adjusting the dose according to an individualized dosing regimen

artículo científico publicado en 1996

Application of semilinear canonical correlation to the measurement of the electroencephalographic effects of volatile anaesthetics.

artículo científico publicado en 2002

Comparison of the concentration-dependent effect of sevoflurane on the spinal H-reflex and the EEG in humans.

artículo científico publicado en 2004

Compartmental pharmacokinetics of nefopam during mild hypothermia.

artículo científico publicado en 2012

Concentration-effect relationship of the positive chronotropic and hypokalaemic effects of fenoterol in healthy women of childbearing age

artículo científico publicado en 1996

Current insights in the complexities underlying drug-induced cholestasis

scientific article published on 01 July 2019

Does size matter?

scientific article published on 01 September 1998

Effect of Cryopreservation on Enzyme and Transporter Activities in Suspended and Sandwich Cultured Rat Hepatocytes

artículo científico publicado en 2018

Electroencephalogram approximate entropy correctly classifies the occurrence of burst suppression pattern as increasing anesthetic drug effect.

artículo científico publicado en 2000

Fexofenadine, a Putative In Vivo P-glycoprotein Probe, Fails to Predict Clearance of the Substrate Tacrolimus in Renal Recipients.

artículo científico publicado en 2017

Model-based control of mechanical ventilation: design and clinical validation.

artículo científico publicado en 2004

Non-steady state analysis of the pharmacokinetic interaction between propofol and remifentanil.

artículo científico publicado en 2002

Noxious stimulation response index: a novel anesthetic state index based on hypnotic-opioid interaction

artículo científico publicado en 2010

On the modeling of drug induced respiratory depression in the non-steady-state.

artículo científico publicado en 2008

Optimising infliximab induction dosing for patients with ulcerative colitis

scientific article published on 10 February 2019

Optimizing dose regimens and fixed dose combination ratios in clinical trials.

artículo científico publicado en 2015

Pharmacodynamic interaction between propofol and remifentanil regarding hypnosis, tolerance of laryngoscopy, bispectral index, and electroencephalographic approximate entropy.

artículo científico publicado en 2004

Pharmacodynamic interaction of nitrous oxide with sevoflurane, desflurane, isoflurane and enflurane in surgical patients: measurements by effects on EEG median power frequency.

artículo científico publicado en 2001

Pharmacodynamic modelling of the analgesic effects of piritramide in postoperative patients

artículo científico publicado el 1 de agosto de 1997

Pharmacokinetic interactions among imatinib, bosentan and sildenafil, and their clinical implications in severe pulmonary arterial hypertension.

artículo científico publicado en 2015

Pharmacokinetic-pharmacodynamic modeling of the respiratory depressant effect of alfentanil.

artículo científico publicado en 1999

Pharmacokinetics of piritramide after an intravenous bolus in surgical patients

scientific article published on 01 September 1996

Piritramide and alfentanil display similar respiratory depressant potency.

artículo científico publicado en 2003

Population pharmacokinetic analysis for 10-monohydroxy derivative of oxcarbazepine in pediatric epileptic patients shows no difference between Japanese and other ethnicities.

artículo científico publicado en 2014

Population pharmacokinetics of piritramide in surgical patients.

artículo científico publicado en 1999

Population pharmacokinetics of sevoflurane in conjunction with the AnaConDa: toward target-controlled infusion of volatiles into the breathing system.

artículo científico publicado en 2008

Probability to tolerate laryngoscopy and noxious stimulation response index as general indicators of the anaesthetic potency of sevoflurane, propofol, and remifentanil.

artículo científico publicado en 2016

Propofol and remifentanil pharmacodynamic interaction during orthopedic surgical procedures as measured by effects on bispectral index.

artículo científico publicado en 2001

Response surface modeling of the interaction between propofol and sevoflurane.

artículo científico publicado en 2009

The pharmacokinetics of piritramide after prolonged administration to intensive care patients.

artículo científico publicado en 2004

The well-being model: a new drug interaction model for positive and negative effects.

artículo científico publicado en 2006

[Pharmacokinetic-pharmacodynamic models for inhaled anaesthetics]

artículo científico publicado en 2007