Lista de obras - Tomasz Janecki - Dominio Público Uruguay

4-Methylideneisoxazolidin-5-ones--a new class of alpha-methylidene-gamma-lactones with high cytostatic activity.

artículo científico publicado en 2005

A New Hybrid δ-Lactone Induces Apoptosis and Potentiates Anticancer Activity of Taxol in HL-60 Human Leukemia Cells

artículo científico publicado en 2020

Anticancer Activity of New Synthetic α-Methylene-δ-Lactones on Two Breast Cancer Cell Lines

artículo científico publicado en 2013

Anticancer activity and radiosensitization effect of methyleneisoxazolidin-5-ones in hepatocellular carcinoma HepG2 cells.

artículo científico publicado en 2016

Anticancer activity of new molecular hybrids combining 1,4-naphthalenedione motif with phosphonic acid moiety in hepatocellular carcinoma HepG2 cells.

artículo científico publicado en 2016

Anticancer properties of a new hybrid analog AD-013 combining a coumarin scaffold with an α-methylene-δ-lactone motif.

artículo científico publicado en 2017

Anticancer properties of new synthetic hybrid molecules combining naphtho[2,3-b]furan-4,9-dione or benzo[f]indole-4,9-dione motif with phosphonate subunit

artículo científico publicado en 2016

Anticancer properties of novel 4-methylene-1,2-diphenylpyrazolidin-3-ones

artículo científico publicado en 2015

Antide B, an antagonist of LHRH with cis-3-(4-pyrazinylcarbonylaminocyclohexyl)alanine in position 5

artículo científico publicado en 1995

Apoptosis-mediated cytotoxic effects of parthenolide and the new synthetic analog MZ-6 on two breast cancer cell lines

artículo científico publicado en 2012

Combined effects of anticancer drugs and new synthetic α-methylene-δ-lactones on MCF-7 cells

artículo científico publicado en 2015

Comparison of anti-invasive activity of parthenolide and 3-isopropyl-2-methyl-4-methyleneisoxazolidin-5-one (MZ-6)--a new compound with α-methylene-γ-lactone motif--on two breast cancer cell lines.

artículo científico publicado en 2011

Cyclic side-chain-linked opioid analogs utilizing cis- and trans-4-aminocyclohexyl-D-alanine

artículo científico publicado en 2014

Design, synthesis and cytotoxic evaluation of 4-methylidenepyrazolidin-3-ones

artículo científico publicado en 2015

Effect of 2′,6′-dimethyl-l-tyrosine (Dmt) on pharmacological activity of cyclic endomorphin-2 and morphiceptin analogs

scientific article published on 20 October 2011

Effective antagonists of luteinizing hormone releasing hormone modified at position one

artículo científico publicado en 1993

Enantioselective synthesis and cytotoxic evaluation of 4,5-dihydro-5-[aryl(hydroxy)methyl]-3-methylidenefuran-2(3H)-ones.

artículo científico publicado en 2005

Enzymatic degradation studies of endomorphin-2 and its analogs containing N-methylated amino acids.

artículo científico publicado en 2005

Involvement of a coumarin analog AD-013 in the DNA damage response pathways in MCF-7 cells

scholarly article by Angelika Długosz published in October 2018

Involvement of α-methylene-γ- and δ-lactones in the suppression of multidrug resistance in MCF-7 cells

scientific article published on 10 January 2018

Mechanistic and synthetic aspects of the reaction of gamma-halogeno-alpha,beta-unsaturated ketones and esters with simple trialkyl phosphites.

artículo científico publicado en 2003

Natural and synthetic α-methylenelactones and α-methylenelactams with anticancer potential ⬇️

artículo científico publicado el 28 de enero de 2012

New Chiral Ebselen Analogues with Antioxidant and Cytotoxic Potential.

artículo científico publicado en 2017

New glutathione peroxidase mimetics-Insights into antioxidant and cytotoxic activity.

artículo científico publicado en 2016

New stereocontrolled synthesis and biological evaluation of 5-(1'-hydroxyalkyl)-3-methylidenetetrahydro-2-furanones as potential cytotoxic agents.

artículo científico publicado en 2002

New uracil analog with exocyclic methylidene group as potential anticancer agent

scientific article published on 10 December 2019

New, simple and versatile synthesis of 4,6-disubstituted pyridazin-3(2H)-ones

scientific article published on 28 February 2008

Novel highly potent mu-opioid receptor antagonist based on endomorphin-2 structure

artículo científico publicado en 2008

Novel synthesis, cytotoxic evaluation, and structure-activity relationship studies of a series of alpha-alkylidene-gamma-lactones and lactams.

artículo científico publicado en 2005

Opioid receptors and their ligands

artículo científico publicado en 2004

Pharmacological properties of novel cyclic pentapeptides with µ-opioid receptor agonist activity

artículo científico publicado en 2014

Reduced-Size Antagonists of Luteinizing Hormone-Releasing Hormone Active in Vitro ⬇️

artículo científico publicado el 21 de julio de 1995

Ring size in cyclic endomorphin-2 analogs modulates receptor binding affinity and selectivity.

artículo científico publicado en 2015

Supramolecular architecture in azaheterocyclic phosphonates. III. Structures of an ethyl phosphonamidate and an ethyl phosphonate

scientific article published on 13 July 2018

Synthesis and Anticancer Properties of New 3-Methylidene-1-sulfonyl-2,3-dihydroquinolin-4(1H)-ones

artículo científico publicado en 2022

Synthesis and Cytotoxic Evaluation of 3-Methylidenechroman-4-ones

scientific article published on 15 May 2019

Synthesis and biological activity of N-methylated analogs of endomorphin-2

scientific article published on 06 September 2005

Synthesis and biological evaluation of 4-methylideneisoxazolidin-5-ones--a new class of highly cytotoxic alpha-methylidene-gamma-lactones

artículo científico publicado en 2006

Synthesis and biological evaluation of α-methylidene-δ-lactones with 3,4-dihydrocoumarin skeleton ⬇️

artículo científico publicado el 19 de junio de 2012

Synthesis and cytotoxic activity of gamma-aryl substituted alpha-alkylidene-gamma-lactones and alpha-alkylidene-gamma-lactams.

artículo científico publicado en 2008

Synthesis and cytotoxic evaluation of beta-alkyl or beta-aryl-delta-methyl-alpha-methylene-delta-lactones. Comparison with the corresponding gamma-lactones.

artículo científico publicado en 2009

Synthesis of 2,2,6-Trisubstituted 5-Methylidene-tetrahydropyran-4-ones with Anticancer Activity

scientific article published on 30 January 2020

Synthesis of 3-Methylidene-1-tosyl-2,3-dihydroquinolin-4(1H)-ones as Potent Cytotoxic Agents

scientific article published on 08 August 2018

Synthesis of 4,4-Disubstituted 3-Methylidenechroman-2-ones as Potent Anticancer Agents.

artículo científico publicado en 2017

The structural features of effective antagonists of the luteinizing hormone releasing hormone

scientific article published on 01 June 1994

Lista de obras de Tomasz Janecki

4-Methylideneisoxazolidin-5-ones--a new class of alpha-methylidene-gamma-lactones with high cytostatic activity.

A New Hybrid δ-Lactone Induces Apoptosis and Potentiates Anticancer Activity of Taxol in HL-60 Human Leukemia Cells

Anticancer Activity of New Synthetic α-Methylene-δ-Lactones on Two Breast Cancer Cell Lines

Anticancer activity and radiosensitization effect of methyleneisoxazolidin-5-ones in hepatocellular carcinoma HepG2 cells.

Anticancer activity of new molecular hybrids combining 1,4-naphthalenedione motif with phosphonic acid moiety in hepatocellular carcinoma HepG2 cells.

Anticancer properties of a new hybrid analog AD-013 combining a coumarin scaffold with an α-methylene-δ-lactone motif.

Anticancer properties of new synthetic hybrid molecules combining naphtho[2,3-b]furan-4,9-dione or benzo[f]indole-4,9-dione motif with phosphonate subunit

Anticancer properties of novel 4-methylene-1,2-diphenylpyrazolidin-3-ones

Antide B, an antagonist of LHRH with cis-3-(4-pyrazinylcarbonylaminocyclohexyl)alanine in position 5

Apoptosis-mediated cytotoxic effects of parthenolide and the new synthetic analog MZ-6 on two breast cancer cell lines

Combined effects of anticancer drugs and new synthetic α-methylene-δ-lactones on MCF-7 cells

Comparison of anti-invasive activity of parthenolide and 3-isopropyl-2-methyl-4-methyleneisoxazolidin-5-one (MZ-6)--a new compound with α-methylene-γ-lactone motif--on two breast cancer cell lines.

Cyclic side-chain-linked opioid analogs utilizing cis- and trans-4-aminocyclohexyl-D-alanine

Design, synthesis and cytotoxic evaluation of 4-methylidenepyrazolidin-3-ones

Effect of 2′,6′-dimethyl-l-tyrosine (Dmt) on pharmacological activity of cyclic endomorphin-2 and morphiceptin analogs

Effective antagonists of luteinizing hormone releasing hormone modified at position one

Enantioselective synthesis and cytotoxic evaluation of 4,5-dihydro-5-[aryl(hydroxy)methyl]-3-methylidenefuran-2(3H)-ones.

Enzymatic degradation studies of endomorphin-2 and its analogs containing N-methylated amino acids.

Involvement of a coumarin analog AD-013 in the DNA damage response pathways in MCF-7 cells

Involvement of α-methylene-γ- and δ-lactones in the suppression of multidrug resistance in MCF-7 cells

Mechanistic and synthetic aspects of the reaction of gamma-halogeno-alpha,beta-unsaturated ketones and esters with simple trialkyl phosphites.

Natural and synthetic α-methylenelactones and α-methylenelactams with anticancer potential ⬇️

New Chiral Ebselen Analogues with Antioxidant and Cytotoxic Potential.

New glutathione peroxidase mimetics-Insights into antioxidant and cytotoxic activity.

New stereocontrolled synthesis and biological evaluation of 5-(1'-hydroxyalkyl)-3-methylidenetetrahydro-2-furanones as potential cytotoxic agents.

New uracil analog with exocyclic methylidene group as potential anticancer agent

New, simple and versatile synthesis of 4,6-disubstituted pyridazin-3(2H)-ones

Novel highly potent mu-opioid receptor antagonist based on endomorphin-2 structure

Novel synthesis, cytotoxic evaluation, and structure-activity relationship studies of a series of alpha-alkylidene-gamma-lactones and lactams.

Opioid receptors and their ligands

Pharmacological properties of novel cyclic pentapeptides with µ-opioid receptor agonist activity

Reduced-Size Antagonists of Luteinizing Hormone-Releasing Hormone Active in Vitro ⬇️

Ring size in cyclic endomorphin-2 analogs modulates receptor binding affinity and selectivity.

Supramolecular architecture in azaheterocyclic phosphonates. III. Structures of an ethyl phosphonamidate and an ethyl phosphonate

Synthesis and Anticancer Properties of New 3-Methylidene-1-sulfonyl-2,3-dihydroquinolin-4(1H)-ones

Synthesis and Cytotoxic Evaluation of 3-Methylidenechroman-4-ones

Synthesis and biological activity of N-methylated analogs of endomorphin-2

Synthesis and biological evaluation of 4-methylideneisoxazolidin-5-ones--a new class of highly cytotoxic alpha-methylidene-gamma-lactones

Synthesis and biological evaluation of α-methylidene-δ-lactones with 3,4-dihydrocoumarin skeleton ⬇️

Synthesis and cytotoxic activity of gamma-aryl substituted alpha-alkylidene-gamma-lactones and alpha-alkylidene-gamma-lactams.

Synthesis and cytotoxic evaluation of beta-alkyl or beta-aryl-delta-methyl-alpha-methylene-delta-lactones. Comparison with the corresponding gamma-lactones.

Synthesis of 2,2,6-Trisubstituted 5-Methylidene-tetrahydropyran-4-ones with Anticancer Activity

Synthesis of 3-Methylidene-1-tosyl-2,3-dihydroquinolin-4(1H)-ones as Potent Cytotoxic Agents

Synthesis of 4,4-Disubstituted 3-Methylidenechroman-2-ones as Potent Anticancer Agents.

The structural features of effective antagonists of the luteinizing hormone releasing hormone