Lista de obras -

Chromatin remodeller CHD7 is required for GABAergic neuron development by promoting PAQR3 expression

artículo científico publicado en 2021

Cytometric profiling in multiple sclerosis uncovers patient population structure and a reduction of CD8low cells

artículo científico publicado en 2008

Deciphering genetic interactions between ALS genes using C. elegans

artículo científico publicado en 2014

Evaluation of longevity enhancing compounds against transactive response DNA-binding protein-43 neuronal toxicity.

artículo científico publicado en 2013

Expanded polyglutamines in Caenorhabditis elegans cause axonal abnormalities and severe dysfunction of PLM mechanosensory neurons without cell death ⬇️

artículo científico publicado el 30 de octubre de 2001

Expression of human Bcl-xL (Ser49) and (Ser62) mutants in Caenorhabditis elegans causes germline defects and aneuploidy

artículo científico publicado en 2017

Fishing for causes and cures of motor neuron disorders

artículo científico

Fragile lifespan expansion by dietary mitohormesis in C. elegans.

artículo científico

Genome-wide association study of determinants of anti-cyclic citrullinated peptide antibody titer in adults with rheumatoid arthritis

artículo científico publicado en 2009

Glucose delays age-dependent proteotoxicity.

artículo científico publicado en 2012

Heritable transmission of stress resistance by high dietary glucose in Caenorhabditis elegans

artículo científico publicado en 2014

Huntingtin-interacting protein 1 influences worm and mouse presynaptic function and protects Caenorhabditis elegans neurons against mutant polyglutamine toxicity.

artículo científico publicado en 2007

Insulin signaling in the aging of healthy and proteotoxically stressed mechanosensory neurons

artículo científico publicado en 2014

Integration of β-catenin, sirtuin, and FOXO signaling protects from mutant huntingtin toxicity

scientific journal article

Large-scale functional RNAi screen in C. elegans identifies genes that regulate the dysfunction of mutant polyglutamine neurons.

artículo científico publicado en 2012

Maple Syrup Decreases TDP-43 Proteotoxicity in a Caenorhabditis elegans Model of Amyotrophic Lateral Sclerosis (ALS).

artículo científico publicado en 2016

Modulating the ER stress response attenuates neurodegeneration in a C. elegans model of spinal muscular atrophy

scientific article published on 08 October 2020

Morphological remodeling of C. elegans neurons during aging is modified by compromised protein homeostasis.

artículo científico publicado en 2016

Neurodegeneration in C. elegans models of ALS requires TIR-1/Sarm1 immune pathway activation in neurons. ⬇️

artículo científico publicado en 2015

Peripheral blood expression of nuclear factor-kappab-regulated genes is associated with rheumatoid arthritis disease activity and responds differentially to anti-tumor necrosis factor-alpha versus methotrexate

artículo científico publicado en 2007

Pharmacological reduction of ER stress protects against TDP-43 neuronal toxicity in vivo.

artículo científico publicado en 2013

RNA-Based Therapy Utilizing Oculopharyngeal Muscular Dystrophy Transcript Knockdown and Replacement

artículo científico publicado en 2019

Reduction of polyglutamine toxicity by TDP-43, FUS and progranulin in Huntington's disease models.

artículo científico publicado en 2012

Rescue of ATXN3 neuronal toxicity in Caenorhabditiselegans by chemical modification of endoplasmic reticulum stress.

artículo científico publicado en 2017

Resveratrol rescues mutant polyglutamine cytotoxicity in nematode and mammalian neurons

artículo científico publicado en 2005

Resveratrol rescues mutant polyglutamine cytotoxicity in nematode and mammalian neurons.

artículo científico publicado en 2005

SIRT2 inhibition achieves neuroprotection by decreasing sterol biosynthesis

artículo científico publicado en 2010

Simple animal models for amyotrophic lateral sclerosis drug discovery

artículo científico publicado en 2016

TDP-43 toxicity proceeds via calcium dysregulation and necrosis in aging Caenorhabditis elegans motor neurons

artículo científico publicado en 2014

The stress response factor daf-16/FOXO is required for multiple compound families to prolong the function of neurons with Huntington's disease

artículo científico publicado en 2017

Valproic acid is protective in cellular and worm models of oculopharyngeal muscular dystrophy

Worming forward: amyotrophic lateral sclerosis toxicity mechanisms and genetic interactions in Caenorhabditis elegans

artículo científico publicado en 2014

[Stress-induced propagation of neurodegeneration by wild-type proteins in simple models of ALS]

scientific article published on 26 April 2013

Lista de obras de

Chromatin remodeller CHD7 is required for GABAergic neuron development by promoting PAQR3 expression

Cytometric profiling in multiple sclerosis uncovers patient population structure and a reduction of CD8low cells

Deciphering genetic interactions between ALS genes using C. elegans

Evaluation of longevity enhancing compounds against transactive response DNA-binding protein-43 neuronal toxicity.

Expanded polyglutamines in Caenorhabditis elegans cause axonal abnormalities and severe dysfunction of PLM mechanosensory neurons without cell death ⬇️

Expression of human Bcl-xL (Ser49) and (Ser62) mutants in Caenorhabditis elegans causes germline defects and aneuploidy

Fishing for causes and cures of motor neuron disorders

Fragile lifespan expansion by dietary mitohormesis in C. elegans.

Genome-wide association study of determinants of anti-cyclic citrullinated peptide antibody titer in adults with rheumatoid arthritis

Glucose delays age-dependent proteotoxicity.

Heritable transmission of stress resistance by high dietary glucose in Caenorhabditis elegans

Huntingtin-interacting protein 1 influences worm and mouse presynaptic function and protects Caenorhabditis elegans neurons against mutant polyglutamine toxicity.

Insulin signaling in the aging of healthy and proteotoxically stressed mechanosensory neurons

Integration of β-catenin, sirtuin, and FOXO signaling protects from mutant huntingtin toxicity

Large-scale functional RNAi screen in C. elegans identifies genes that regulate the dysfunction of mutant polyglutamine neurons.

Maple Syrup Decreases TDP-43 Proteotoxicity in a Caenorhabditis elegans Model of Amyotrophic Lateral Sclerosis (ALS).

Modulating the ER stress response attenuates neurodegeneration in a C. elegans model of spinal muscular atrophy

Morphological remodeling of C. elegans neurons during aging is modified by compromised protein homeostasis.

Neurodegeneration in C. elegans models of ALS requires TIR-1/Sarm1 immune pathway activation in neurons. ⬇️

Peripheral blood expression of nuclear factor-kappab-regulated genes is associated with rheumatoid arthritis disease activity and responds differentially to anti-tumor necrosis factor-alpha versus methotrexate

Pharmacological reduction of ER stress protects against TDP-43 neuronal toxicity in vivo.

RNA-Based Therapy Utilizing Oculopharyngeal Muscular Dystrophy Transcript Knockdown and Replacement

Reduction of polyglutamine toxicity by TDP-43, FUS and progranulin in Huntington's disease models.

Rescue of ATXN3 neuronal toxicity in Caenorhabditiselegans by chemical modification of endoplasmic reticulum stress.

Resveratrol rescues mutant polyglutamine cytotoxicity in nematode and mammalian neurons

Resveratrol rescues mutant polyglutamine cytotoxicity in nematode and mammalian neurons.

SIRT2 inhibition achieves neuroprotection by decreasing sterol biosynthesis

Simple animal models for amyotrophic lateral sclerosis drug discovery

TDP-43 toxicity proceeds via calcium dysregulation and necrosis in aging Caenorhabditis elegans motor neurons

The stress response factor daf-16/FOXO is required for multiple compound families to prolong the function of neurons with Huntington's disease

Valproic acid is protective in cellular and worm models of oculopharyngeal muscular dystrophy

Worming forward: amyotrophic lateral sclerosis toxicity mechanisms and genetic interactions in Caenorhabditis elegans

[Stress-induced propagation of neurodegeneration by wild-type proteins in simple models of ALS]