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BET bromodomain inhibitors and agonists of the beta-2 adrenergic receptor identified in screens for compounds that inhibit DUX4 expression in FSHD muscle cells.

artículo científico publicado en 2017

Bromodomain protein Brd3 associates with acetylated GATA1 to promote its chromatin occupancy at erythroid target genes

artículo científico publicado en 2011

Clinically Advanced p38 Inhibitors Suppress DUX4 Expression in Cellular and Animal Models of Facioscapulohumeral Muscular Dystrophy

scientific article published on 12 June 2019

Comparative analysis of mitosis-specific antibodies for bulk purification of mitotic populations by fluorescence-activated cell sorting.

artículo científico publicado en 2014

DUX4 Suppresses MHC Class I to Promote Cancer Immune Evasion and Resistance to Checkpoint Blockade

scientific article published on 18 July 2019

DUX4-induced dsRNA and MYC mRNA stabilization activate apoptotic pathways in human cell models of facioscapulohumeral dystrophy

artículo científico publicado en 2017

Facioscapulohumeral dystrophy: Activating an early embryonic transcriptional program in human skeletal muscle.

artículo científico publicado en 2018

Functions of BET proteins in erythroid gene expression

artículo científico publicado en 2015

Invertebrate insights into autism.

artículo científico publicado en 2010

MRI-informed muscle biopsies correlate MRI with pathology and DUX4 target gene expression in FSHD

article

Molecular architecture of CTCFL.

artículo científico publicado en 2010

NuRD and CAF-1-mediated silencing of the D4Z4 array is modulated by DUX4-induced MBD3L proteins.

artículo científico publicado en 2018

Pluripotent stem cells reveal erythroid-specific activities of the GATA1 N-terminus

artículo científico publicado en 2015

Role of SWI/SNF in acute leukemia maintenance and enhancer-mediated Myc regulation

artículo científico publicado en 2013

The BRD3 ET domain recognizes a short peptide motif through a mechanism that is conserved across chromatin remodelers and transcriptional regulators.

artículo científico publicado en 2018

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