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A titrate-to-goal study of switching patients uncontrolled on antihypertensive monotherapy to fixed-dose combinations of amlodipine and olmesartan medoxomil ± hydrochlorothiazide.

artículo científico publicado en 2011

Abnormalities of the P16INK4A gene in thyroid cancer cell lines

scientific article published on 01 December 1996

An analysis of replicative senescence in dermal fibroblasts derived from chronic leg wounds predicts that telomerase therapy would fail to reverse their disease-specific cellular and proteolytic phenotype

artículo científico publicado en 2003

Clinical implications of telomerase detection.

artículo científico publicado en 2001

Direct evidence from siRNA-directed "knock down" that p16(INK4a) is required for human fibroblast senescence and for limiting ras-induced epithelial cell proliferation

artículo científico publicado en 2004

Dissociation of telomere dynamics from telomerase activity in human thyroid cancer cells.

artículo científico publicado en 1998

Does telomere shortening drive selection for p53 mutation in human cancer?

artículo científico publicado en 1995

Fibroblast clones from patients with Hutchinson-Gilford progeria can senesce despite the presence of telomerase

artículo científico publicado en 2004

High frequency deletion of the tumour suppressor gene P16INK4a (MTS1) in human thyroid cancer cell lines

artículo científico publicado en 1996

Interactions of the transcription/DNA repair factor TFIIH and XP repair proteins with DNA lesions in a cell-free repair assay.

artículo científico publicado en 1998

Is TFIIH an activator of the p53-mediated G1/S checkpoint?

artículo científico publicado en 1995

Metallothionein overexpression in human brain tumours.

artículo científico

Mutation and expression of the XPA gene in revertants and hybrids of a xeroderma pigmentosum cell line.

artículo científico publicado en 1994

Nucleotide excision repair of DNA by mammalian cell extracts and purified proteins

scientific article published on 01 January 1993

Preferential binding of the xeroderma pigmentosum group A complementing protein to damaged DNA.

artículo científico publicado en 1993

S phase cell-cycle arrest following DNA damage is independent of the p53/p21(WAF1) signalling pathway

scientific article published on 01 March 1996

Simian virus 40 detection in human mesothelioma: reliability and significance of the available molecular evidence.

artículo científico publicado en 2001

Telomerase activity and telomere length in thyroid neoplasia: biological and clinical implications

artículo científico publicado en 2001

Telomerase activity is a biomarker for high grade malignant peripheral nerve sheath tumors in neurofibromatosis type 1 individuals

scientific article published on 01 March 2008

Telomerase and cellular lifespan: ending the debate?

artículo científico publicado en 1998

Telomerase prevents the accelerated cell ageing of Werner syndrome fibroblasts

artículo científico publicado en 2000

The Genome Stability Network

artículo científico publicado en 2005

Tumor-environment biomimetics delay peritoneal metastasis formation by deceiving and redirecting disseminated cancer cells.

artículo científico publicado en 2015

p53-Dependent growth arrest and altered p53-immunoreactivity following metabolic labelling with 32P ortho-phosphate in human fibroblasts

artículo científico publicado en 1999