Lista de obras - L Schurgers - Dominio Público Uruguay

A Combination of Tamarindus indica seeds and Curcuma longa Rhizome Extracts Improves Knee Joint Function and Alleviates Pain in Non-Arthritic Adults Following Physical Activity

scientific article published on 02 June 2019

A Novel Biomimetic Tool for Assessing Vitamin K Status Based on Molecularly Imprinted Polymers.

artículo científico publicado en 2018

Administration of vitamin K does not counteract the ectopic mineralization of connective tissues inAbcc6-/-mice, a model for pseudoxanthoma elasticum ⬇️

artículo científico publicado el 15 de febrero de 2011

Annexin A1 as Neuroprotective Determinant for Blood-Brain Barrier Integrity in Neonatal Hypoxic-Ischemic Encephalopathy

scientific article published on 24 January 2019

Annexin A5 reduces early plaque formation in ApoE -/- mice.

artículo científico publicado en 2017

AnnexinA5-pHrodo: a new molecular probe for measuring efferocytosis

scientific article published in Scientific Reports

AnxA5 reduces plaque inflammation of advanced atherosclerotic lesions in apoE(-/-) mice

artículo científico publicado en 2014

Aortic Valve Calcium Associates with All-Cause Mortality Independent of Coronary Artery Calcium and Inflammation in Patients with End-Stage Renal Disease

scientific article published on 24 February 2020

Apolipoprotein E Regulates Amyloid Formation within Endosomes of Pigment Cells

artículo científico publicado en 2015

Associations between body composition, circulating interleukin-1 receptor antagonist, osteocalcin, and insulin metabolism in active acromegaly

artículo científico publicado en 2009

Atypical presentation of pseudoxanthoma elasticum with abdominal cutis laxa: evidence for a spectrum of ectopic calcification disorders?

artículo científico publicado en 2011

Bicuspid Aortic Valve Stenosis and the Effect of Vitamin K2 on Calcification Using 18F-Sodium Fluoride Positron Emission Tomography/Magnetic Resonance: The BASIK2 Rationale and Trial Design.

artículo científico publicado en 2018

Calcific aortic valve stenosis: hard disease in the heart: A biomolecular approach towards diagnosis and treatment.

artículo científico publicado en 2017

Calcification inhibitors in vascular calciphylaxis associated with normal renal function

artículo científico publicado en 2012

Calcium regulates key components of vascular smooth muscle cell-derived matrix vesicles to enhance mineralization.

artículo científico publicado en 2011

Cathepsin K Deficiency Prevents the Aggravated Vascular Remodeling Response to Flow Cessation in ApoE-/- Mice

artículo científico publicado en 2016

Characterisation and potential diagnostic value of circulating matrix Gla protein (MGP) species.

artículo científico publicado en 2010

Cheese and Healthy Diet: Associations With Incident Cardio-Metabolic Diseases and All-Cause Mortality in the General Population

artículo científico publicado en 2019

Chronic Kidney Disease Circulating Calciprotein Particles and Extracellular Vesicles Promote Vascular Calcification: A Role for GRP (Gla-Rich Protein).

artículo científico publicado en 2018

Chronic mineral dysregulation promotes vascular smooth muscle cell adaptation and extracellular matrix calcification.

artículo científico publicado en 2009

Circulating annexin A5 levels are associated with carotid intima-media thickness but not coronary plaque composition.

artículo científico publicado en 2017

Circulating annexin A5 predicts mortality in patients with heart failure

artículo científico publicado en 2015

Circulating levels of non-phosphorylated undercarboxylated matrix Gla protein are associated with disease severity in patients with chronic heart failure

scientific article published on 01 August 2011

Comparison of menaquinone-4 and menaquinone-7 bioavailability in healthy women.

artículo científico publicado en 2012

Coronary Artery Calcification: A Janus-Faced Biomarker?

artículo científico publicado en 2017

Decreased Levels of Circulating Carboxylated Osteocalcin in Children with Low Energy Fractures: A Pilot Study.

artículo científico publicado en 2018

Deficiency of myeloid PHD proteins aggravates atherogenesis via macrophage apoptosis and paracrine fibrotic signalling

artículo científico publicado en 2022

Desphospho-Uncarboxylated Matrix-Gla Protein Is Increased Postoperatively in Cardiovascular Risk Patients.

artículo científico publicado en 2018

Differential cellular effects of old and new oral anticoagulants: consequences to the genesis and progression of atherosclerosis

artículo científico publicado en 2014

Does statins promote vascular calcification in chronic kidney disease?

artículo científico publicado en 2016

Ectopic calcification in β-thalassemia patients is associated with increased oxidative stress and lower MGP carboxylation.

artículo científico publicado en 2013

Effect of 6-Month Vitamin D Supplementation on Plasma Matrix Gla Protein in Older Adults

artículo científico publicado en 2019

Effect of low-dose supplements of menaquinone-7 (vitamin K2 ) on the stability of oral anticoagulant treatment: dose-response relationship in healthy volunteers

artículo científico publicado en 2013

High-Dose Menaquinone-7 Supplementation Reduces Cardiovascular Calcification in a Murine Model of Extraosseous Calcification

artículo científico publicado en 2015

Hydrolysed Formula Is a Risk Factor for Vitamin K Deficiency in Infants With Unrecognised Cholestasis ⬇️

artículo científico publicado el 1 de diciembre de 2010

Incorporation of Disulfide Containing Protein Modules into Multivalent Antigenic Conjugates: Generation of Antibodies against the Thrombin-Sensitive Region of Murine Protein S

scientific article published on 13 November 2012

Influence of pH and phosphate concentration on the phosphate binding capacity of five contemporary binders. An in vitro study

artículo científico publicado en 2018

Intimal and medial calcification in relation to cardiovascular risk factors

scientific article published on 13 July 2020

Intra-Section Analysis of Human Coronary Arteries Reveals a Potential Role for Micro-Calcifications in Macrophage Recruitment in the Early Stage of Atherosclerosis

artículo científico publicado en 2015

Lack of evidence does not justify neglect: how can we address unmet medical needs in calciphylaxis?

artículo científico publicado en 2016

Matrix Gla Protein Accumulates at the Border of Regions of Calcification and Normal Tissue in the Media of the Arterial Vessel Wall ⬇️

artículo científico publicado el 30 de noviembre de 2001

Matrix Gla Protein and Alkaline Phosphatase Are Differently Modulated in Human Dermal Fibroblasts from PXE Patients and Controls ⬇️

artículo científico publicado el 6 de diciembre de 2012

Matrix gla protein (MGP): an overexpressed and migration-promoting mesenchymal component in glioblastoma.

artículo científico publicado en 2009

Mechanisms of arterial remodeling: lessons from genetic diseases ⬇️

artículo científico publicado el 13 de diciembre de 2012

Microcalcifications in Early Intimal Lesions of Atherosclerotic Human Coronary Arteries ⬇️

artículo científico publicado el 30 de abril de 2011

Missense mutation of VKORC1 leads to medial arterial calcification in rats

artículo científico publicado en 2018

Molecular Imaging to Identify the Vulnerable Plaque—From Basic Research to Clinical Practice ⬇️

artículo científico publicado el 1 de octubre de 2012

Molecular imaging of cell death in tumors. Increasing annexin A5 size reduces contribution of phosphatidylserine-targeting function to tumor uptake.

artículo científico publicado en 2014

Mutations in the ABCC6 gene as a cause of generalized arterial calcification of infancy: genotypic overlap with pseudoxanthoma elasticum

artículo científico publicado en 2013

Myeloid A disintegrin and metalloproteinase domain 10 deficiency modulates atherosclerotic plaque composition by shifting the balance from inflammation toward fibrosis.

artículo científico publicado en 2015

New Insights into the Pros and Cons of the Clinical Use of Vitamin K Antagonists (VKAs) Versus Direct Oral Anticoagulants (DOACs)

artículo científico publicado en 2015

Off-target effects of oral anticoagulants - vascular effects of vitamin K antagonist and non-vitamin K antagonist oral anticoagulant dabigatran etexilate

artículo científico publicado en 2021

Patients using vitamin K antagonists show increased levels of coronary calcification: an observational study in low-risk atrial fibrillation patients

artículo científico publicado en 2011

Pharmacological Treatment with Annexin A1 Reduces Atherosclerotic Plaque Burden in LDLR-/- Mice on Western Type Diet

artículo científico publicado en 2015

Pharmacological and Nutritional Modulation of Vascular Calcification

scientific article published on 30 December 2019

Phosphate binders affect vitamin K concentration by undesired binding, an in vitro study.

artículo científico publicado en 2017

Platelet extracellular vesicles induce a pro-inflammatory smooth muscle cell phenotype.

artículo científico

Potentiating role of Gas6 and Tyro3, Axl and Mer (TAM) receptors in human and murine platelet activation and thrombus stabilization

scientific journal article

Prevention of vasculopathy by vitamin K supplementation: can we turn fiction into fact?

artículo científico publicado en 2015

Prothrombin Loading of Vascular Smooth Muscle Cell-Derived Exosomes Regulates Coagulation and Calcification.

artículo científico publicado en 2017

Rapidly Progressive Severe Vascular Calcification Sparing the Kidney Allograft Following Warfarin Initiation ⬇️

artículo científico publicado el 1 de diciembre de 2010

Relationship between sclerostin and cardiovascular calcification in hemodialysis patients: a cross-sectional study

artículo científico publicado en 2013

Renal matrix Gla protein expression increases progressively with CKD and predicts renal outcome

artículo científico publicado en 2018

Response to letter to the editor: annexin A5 levels or circulating microparticles: what we see depends mainly on what we look for

artículo científico publicado en 2016

Role of Vascular Smooth Muscle Cell Phenotypic Switching and Calcification in Aortic Aneurysm Formation

scientific article published on 30 May 2019

Role of vitamin K-dependent proteins in the arterial vessel wall ⬇️

artículo científico publicado el 29 de junio de 2011

Sevelamer Use in End-Stage Kidney Disease (ESKD) Patients Associates with Poor Vitamin K Status and High Levels of Gut-Derived Uremic Toxins: A Drug-Bug Interaction?

artículo científico publicado en 2020

Slower Progress of Aortic Valve Calcification With Vitamin K Supplementation: Results From a Prospective Interventional Proof-of-Concept Study.

artículo científico publicado en 2017

Target identification for the diagnosis and intervention of vulnerable atherosclerotic plaques beyond F-fluorodeoxyglucose positron emission tomography imaging: promising tracers on the horizon

artículo científico publicado en 2018

Targeting Coagulation Factor Xa Promotes Regression of Advanced Atherosclerosis in Apolipoprotein-E Deficient Mice

scientific article published on 07 March 2019

The Role of Vascular Smooth Muscle Cells in Arterial Remodeling: Focus on Calcification-Related Processes

scientific article published on 14 November 2019

The associations of fibroblast growth factor 23 and uncarboxylated matrix Gla protein with mortality in coronary artery disease: the Heart and Soul Study.

artículo científico publicado en 2010

The effect of menaquinone-7 supplementation on vascular calcification in patients with diabetes: a randomized, double-blind, placebo-controlled trial

artículo científico publicado en 2019

The realm of vitamin K dependent proteins: shifting from coagulation toward calcification.

artículo científico

The role of kidney transplantation and phosphate binder use in vitamin K status

artículo científico publicado en 2018

Ucma/GRP inhibits phosphate-induced vascular smooth muscle cell calcification via SMAD-dependent BMP signalling.

artículo científico publicado en 2018

Undercarboxylated matrix Gla protein is associated with indices of heart failure and mortality in symptomatic aortic stenosis

artículo científico publicado en 2010

Uremic Toxins and Vascular Calcification-Missing the Forest for All the Trees

scientific article published on 29 September 2020

Use of Cyclic Backbone NGR-Based SPECT to Increase Efficacy of Postmyocardial Infarction Angiogenesis Imaging.

artículo científico publicado en 2017

Vascular CXCR4 Limits Atherosclerosis by Maintaining Arterial Integrity: Evidence From Mouse and Human Studies.

artículo científico publicado en 2017

Vascular Calcification and not Arrhythmia in Idiopathic Atrial Fibrillation Associates with Sex Differences in Diabetic Microvascular Injury miRNA Profiles

scientific article published on 01 January 2019

Vascular calcification in chronic kidney disease: an update.

artículo científico publicado en 2015

Vascular calcification: The price to pay for anticoagulation therapy with vitamin K-antagonists ⬇️

artículo científico publicado el 18 de abril de 2012

Vascular smooth muscle cell calcification is mediated by regulated exosome secretion

artículo científico publicado en 2015

Vitamin K Antagonist Use and Risk for Intracranial Carotid Artery Calcification in Patients With Intracerebral Hemorrhage

scientific article published on 20 December 2019

Vitamin K antagonism aggravates chronic kidney disease-induced neointimal hyperplasia and calcification in arterialized veins: role of vitamin K treatment?

artículo científico publicado en 2015

Vitamin K deficiency in critical ill patients; a prospective observational study

artículo científico publicado en 2018

Vitamin K intake and status are low in hemodialysis patients

scientific article published on 30 May 2012

Vitamin K supplementation increases vitamin K tissue levels but fails to counteract ectopic calcification in a mouse model for pseudoxanthoma elasticum.

artículo científico publicado en 2011

Vitamin K-dependent carboxylation of matrix Gla-protein: a crucial switch to control ectopic mineralization ⬇️

artículo científico publicado el 30 de enero de 2013

Vitamin K1 to slow vascular calcification in haemodialysis patients (VitaVasK trial): a rationale and study protocol.

artículo científico publicado en 2013

Vitamin K2 Needs an RDI Separate from Vitamin K1

artículo científico publicado en 2020

Vitamin K: Double Bonds beyond Coagulation Insights into Differences between Vitamin K1 and K2 in Health and Disease

article

Vitamin K: key vitamin in controlling vascular calcification in chronic kidney disease.

artículo científico publicado en 2013

Vitamin k intake and plasma desphospho-uncarboxylated matrix Gla-protein levels in kidney transplant recipients

artículo científico publicado en 2012

What's in a name? The pharmacy of vitamin K.

artículo científico publicado en 2015

Lista de obras de L Schurgers

A Combination of Tamarindus indica seeds and Curcuma longa Rhizome Extracts Improves Knee Joint Function and Alleviates Pain in Non-Arthritic Adults Following Physical Activity

A Novel Biomimetic Tool for Assessing Vitamin K Status Based on Molecularly Imprinted Polymers.

Administration of vitamin K does not counteract the ectopic mineralization of connective tissues inAbcc6-/-mice, a model for pseudoxanthoma elasticum ⬇️

Annexin A1 as Neuroprotective Determinant for Blood-Brain Barrier Integrity in Neonatal Hypoxic-Ischemic Encephalopathy

Annexin A5 reduces early plaque formation in ApoE -/- mice.

AnnexinA5-pHrodo: a new molecular probe for measuring efferocytosis

AnxA5 reduces plaque inflammation of advanced atherosclerotic lesions in apoE(-/-) mice

Aortic Valve Calcium Associates with All-Cause Mortality Independent of Coronary Artery Calcium and Inflammation in Patients with End-Stage Renal Disease

Apolipoprotein E Regulates Amyloid Formation within Endosomes of Pigment Cells

Associations between body composition, circulating interleukin-1 receptor antagonist, osteocalcin, and insulin metabolism in active acromegaly

Atypical presentation of pseudoxanthoma elasticum with abdominal cutis laxa: evidence for a spectrum of ectopic calcification disorders?

Bicuspid Aortic Valve Stenosis and the Effect of Vitamin K2 on Calcification Using 18F-Sodium Fluoride Positron Emission Tomography/Magnetic Resonance: The BASIK2 Rationale and Trial Design.

Calcific aortic valve stenosis: hard disease in the heart: A biomolecular approach towards diagnosis and treatment.

Calcification inhibitors in vascular calciphylaxis associated with normal renal function

Calcium regulates key components of vascular smooth muscle cell-derived matrix vesicles to enhance mineralization.

Cathepsin K Deficiency Prevents the Aggravated Vascular Remodeling Response to Flow Cessation in ApoE-/- Mice

Characterisation and potential diagnostic value of circulating matrix Gla protein (MGP) species.

Cheese and Healthy Diet: Associations With Incident Cardio-Metabolic Diseases and All-Cause Mortality in the General Population

Chronic Kidney Disease Circulating Calciprotein Particles and Extracellular Vesicles Promote Vascular Calcification: A Role for GRP (Gla-Rich Protein).

Chronic mineral dysregulation promotes vascular smooth muscle cell adaptation and extracellular matrix calcification.

Circulating annexin A5 levels are associated with carotid intima-media thickness but not coronary plaque composition.

Circulating annexin A5 predicts mortality in patients with heart failure

Circulating levels of non-phosphorylated undercarboxylated matrix Gla protein are associated with disease severity in patients with chronic heart failure

Comparison of menaquinone-4 and menaquinone-7 bioavailability in healthy women.

Coronary Artery Calcification: A Janus-Faced Biomarker?

Decreased Levels of Circulating Carboxylated Osteocalcin in Children with Low Energy Fractures: A Pilot Study.

Deficiency of myeloid PHD proteins aggravates atherogenesis via macrophage apoptosis and paracrine fibrotic signalling

Desphospho-Uncarboxylated Matrix-Gla Protein Is Increased Postoperatively in Cardiovascular Risk Patients.

Differential cellular effects of old and new oral anticoagulants: consequences to the genesis and progression of atherosclerosis

Does statins promote vascular calcification in chronic kidney disease?

Ectopic calcification in β-thalassemia patients is associated with increased oxidative stress and lower MGP carboxylation.

Effect of 6-Month Vitamin D Supplementation on Plasma Matrix Gla Protein in Older Adults

Effect of low-dose supplements of menaquinone-7 (vitamin K2 ) on the stability of oral anticoagulant treatment: dose-response relationship in healthy volunteers

High-Dose Menaquinone-7 Supplementation Reduces Cardiovascular Calcification in a Murine Model of Extraosseous Calcification

Hydrolysed Formula Is a Risk Factor for Vitamin K Deficiency in Infants With Unrecognised Cholestasis ⬇️

Incorporation of Disulfide Containing Protein Modules into Multivalent Antigenic Conjugates: Generation of Antibodies against the Thrombin-Sensitive Region of Murine Protein S

Influence of pH and phosphate concentration on the phosphate binding capacity of five contemporary binders. An in vitro study

Intimal and medial calcification in relation to cardiovascular risk factors

Intra-Section Analysis of Human Coronary Arteries Reveals a Potential Role for Micro-Calcifications in Macrophage Recruitment in the Early Stage of Atherosclerosis

Lack of evidence does not justify neglect: how can we address unmet medical needs in calciphylaxis?

Matrix Gla Protein Accumulates at the Border of Regions of Calcification and Normal Tissue in the Media of the Arterial Vessel Wall ⬇️

Matrix Gla Protein and Alkaline Phosphatase Are Differently Modulated in Human Dermal Fibroblasts from PXE Patients and Controls ⬇️

Matrix gla protein (MGP): an overexpressed and migration-promoting mesenchymal component in glioblastoma.

Mechanisms of arterial remodeling: lessons from genetic diseases ⬇️

Microcalcifications in Early Intimal Lesions of Atherosclerotic Human Coronary Arteries ⬇️

Missense mutation of VKORC1 leads to medial arterial calcification in rats

Molecular Imaging to Identify the Vulnerable Plaque—From Basic Research to Clinical Practice ⬇️

Molecular imaging of cell death in tumors. Increasing annexin A5 size reduces contribution of phosphatidylserine-targeting function to tumor uptake.

Mutations in the ABCC6 gene as a cause of generalized arterial calcification of infancy: genotypic overlap with pseudoxanthoma elasticum

Myeloid A disintegrin and metalloproteinase domain 10 deficiency modulates atherosclerotic plaque composition by shifting the balance from inflammation toward fibrosis.

New Insights into the Pros and Cons of the Clinical Use of Vitamin K Antagonists (VKAs) Versus Direct Oral Anticoagulants (DOACs)

Off-target effects of oral anticoagulants - vascular effects of vitamin K antagonist and non-vitamin K antagonist oral anticoagulant dabigatran etexilate

Patients using vitamin K antagonists show increased levels of coronary calcification: an observational study in low-risk atrial fibrillation patients

Pharmacological Treatment with Annexin A1 Reduces Atherosclerotic Plaque Burden in LDLR-/- Mice on Western Type Diet

Pharmacological and Nutritional Modulation of Vascular Calcification

Phosphate binders affect vitamin K concentration by undesired binding, an in vitro study.

Platelet extracellular vesicles induce a pro-inflammatory smooth muscle cell phenotype.

Potentiating role of Gas6 and Tyro3, Axl and Mer (TAM) receptors in human and murine platelet activation and thrombus stabilization

Prevention of vasculopathy by vitamin K supplementation: can we turn fiction into fact?

Prothrombin Loading of Vascular Smooth Muscle Cell-Derived Exosomes Regulates Coagulation and Calcification.

Rapidly Progressive Severe Vascular Calcification Sparing the Kidney Allograft Following Warfarin Initiation ⬇️

Relationship between sclerostin and cardiovascular calcification in hemodialysis patients: a cross-sectional study

Renal matrix Gla protein expression increases progressively with CKD and predicts renal outcome

Response to letter to the editor: annexin A5 levels or circulating microparticles: what we see depends mainly on what we look for

Role of Vascular Smooth Muscle Cell Phenotypic Switching and Calcification in Aortic Aneurysm Formation

Role of vitamin K-dependent proteins in the arterial vessel wall ⬇️

Sevelamer Use in End-Stage Kidney Disease (ESKD) Patients Associates with Poor Vitamin K Status and High Levels of Gut-Derived Uremic Toxins: A Drug-Bug Interaction?

Slower Progress of Aortic Valve Calcification With Vitamin K Supplementation: Results From a Prospective Interventional Proof-of-Concept Study.

Target identification for the diagnosis and intervention of vulnerable atherosclerotic plaques beyond F-fluorodeoxyglucose positron emission tomography imaging: promising tracers on the horizon

Targeting Coagulation Factor Xa Promotes Regression of Advanced Atherosclerosis in Apolipoprotein-E Deficient Mice

The Role of Vascular Smooth Muscle Cells in Arterial Remodeling: Focus on Calcification-Related Processes

The associations of fibroblast growth factor 23 and uncarboxylated matrix Gla protein with mortality in coronary artery disease: the Heart and Soul Study.

The effect of menaquinone-7 supplementation on vascular calcification in patients with diabetes: a randomized, double-blind, placebo-controlled trial

The realm of vitamin K dependent proteins: shifting from coagulation toward calcification.

The role of kidney transplantation and phosphate binder use in vitamin K status

Ucma/GRP inhibits phosphate-induced vascular smooth muscle cell calcification via SMAD-dependent BMP signalling.

Undercarboxylated matrix Gla protein is associated with indices of heart failure and mortality in symptomatic aortic stenosis

Uremic Toxins and Vascular Calcification-Missing the Forest for All the Trees

Use of Cyclic Backbone NGR-Based SPECT to Increase Efficacy of Postmyocardial Infarction Angiogenesis Imaging.