Lista de obras - Karen Horsburgh - Dominio Público Uruguay

4-Hydroxynonenal immunoreactivity is increased in human hippocampus after global ischemia.

artículo científico publicado en 2001

4-Sodium phenyl butyric acid has both efficacy and counter-indicative effects in the treatment of Col4a1 disease

article

APOE epsilon3 gene transfer attenuates brain damage after experimental stroke

artículo científico publicado en 2006

Activation of Nrf2-regulated glutathione pathway genes by ischemic preconditioning

artículo científico

Ageing causes prominent neurovascular dysfunction associated with loss of astrocytic contacts and gliosis.

artículo científico publicado en 2016

Alterations in ApoE and ApoJ in relation to degeneration and regeneration in a mouse model of entorhinal cortex lesion.

artículo científico publicado en 2001

Angiotensin II-inhibiting drugs have no effect on intraneuronal Aβ or oligomeric Aβ levels in a triple transgenic mouse model of Alzheimer's disease.

artículo científico publicado en 2011

Angiotensin II-inhibition: effect on Alzheimer's pathology in the aged triple transgenic mouse.

artículo científico publicado en 2012

ApoE isoform-specific regulation of regeneration in the peripheral nervous system

artículo científico publicado en 2011

Apolipoprotein E and the CNS response to injury.

artículo científico publicado en 1998

Astrocyte-specific overexpression of Nrf2 protects against optic tract damage and behavioural alterations in a mouse model of cerebral hypoperfusion

scientific article published in Scientific Reports

Axon-glial disruption: the link between vascular disease and Alzheimer's disease?

artículo científico

Chronic cerebral hypoperfusion alters amyloid-β peptide pools leading to cerebral amyloid angiopathy, microinfarcts and haemorrhages in Tg-SwDI mice

artículo científico publicado en 2017

Chronic cerebral hypoperfusion: a key mechanism leading to vascular cognitive impairment and dementia. Closing the translational gap between rodent models and human vascular cognitive impairment and dementia

artículo científico publicado en 2017

Controlled hypertension induces cerebrovascular and gene alterations in Cyp1a1-Ren2 transgenic rats.

artículo científico publicado en 2013

Differential alterations in the expression and activity of matrix metalloproteinases 2 and 9 after transient cerebral ischemia in mice

artículo científico publicado en 2004

Differential alterations of second messenger systems and cerebral glucose use following excitotoxic lesion of rat cerebral cortex ⬇️

artículo científico publicado el 1 de noviembre de 1991

Dimethyl fumarate improves white matter function following severe hypoperfusion: Involvement of microglia/macrophages and inflammatory mediators.

artículo científico publicado en 2017

Effects of environmental enrichment on white matter glial responses in a mouse model of chronic cerebral hypoperfusion ⬇️

artículo científico publicado en 2017

Endocytic pathway alterations in human hippocampus after global ischemia and the influence of APOE genotype

artículo científico publicado en 2003

Estrogen is neuroprotective via an apolipoprotein E-dependent mechanism in a mouse model of global ischemia.

artículo científico publicado en 2002

Extension of cerebral hypoperfusion and ischaemic pathology beyond MCA territory after intraluminal filament occlusion in C57Bl/6J mice

artículo científico publicado en 2004

Focal increases in [3H]forskolin and [3H]phorbol 12,13-dibutyrate binding in the rat brain following lesions of the medial septum.

artículo científico publicado en 1993

Forebrain mineralocorticoid receptor overexpression enhances memory, reduces anxiety and attenuates neuronal loss in cerebral ischaemia

artículo científico publicado en 2007

Frontal white matter hyperintensities, clasmatodendrosis and gliovascular abnormalities in ageing and post-stroke dementia ⬇️

artículo científico publicado en 2015

Gliovascular disruption and cognitive deficits in a mouse model with features of small vessel disease

artículo científico publicado en 2015

Gradual cerebral hypoperfusion in spontaneously hypertensive rats induces slowly evolving white matter abnormalities and impairs working memory.

artículo científico publicado en 2015

Hypertension fails to disrupt white matter integrity in young or aged Fisher (F44) Cyp1a1Ren2 transgenic rats

artículo científico publicado en 2014

Impact of age on the cerebrovascular proteomes of wild-type and Tg-SwDI mice

artículo científico publicado en 2014

Impaired neuronal plasticity in transgenic mice expressing human apolipoprotein E4 compared to E3 in a model of entorhinal cortex lesion.

artículo científico publicado en 2001

Intracortical Glutamate Perfusionin VivoInduces Cellular Alterations in Specific Protein Kinase C Isoforms and Amyloid Precursor Protein

scientific article published on 01 February 1997

Intraventricular Infusion of Apolipoprotein E Ameliorates Acute Neuronal Damage after Global Cerebral Ischemia in Mice

artículo científico publicado en 2000

Kindling-induced changes of protein kinase C levels in hippocampus and neocortex

artículo científico publicado el 1 de enero de 1992

Long-term cilostazol treatment reduces gliovascular damage and memory impairment in a mouse model of chronic cerebral hypoperfusion

artículo científico publicado en 2017

MRI is a sensitive marker of subtle white matter pathology in hypoperfused mice

artículo científico publicado en 2010

Marked alterations in the cellular localisation and levels of apolipoprotein E following acute subdural haematoma in rat.

artículo científico publicado en 1997

Mild fluid percussion injury in mice produces evolving selective axonal pathology and cognitive deficits relevant to human brain injury

artículo científico publicado en 2010

Mild oxidative stress activates Nrf2 in astrocytes, which contributes to neuroprotective ischemic preconditioning.

artículo científico publicado en 2010

Minimal ischaemic neuronal damage and HSP70 expression in MF1 strain mice following bilateral common carotid artery occlusion.

artículo científico publicado en 2001

Minocycline reduces microgliosis and improves subcortical white matter function in a model of cerebral vascular disease

artículo científico publicado en 2017

Neuroprotection after transient global cerebral ischemia in Wld(s) mutant mice.

artículo científico publicado en 2004

Neuroprotective effect of adenoviral-mediated gene transfer of TIMP-1 and -2 in ischemic brain injury.

artículo científico publicado en 2007

Proteomic analysis of mitochondria in APOE transgenic mice and in response to an ischemic challenge

artículo científico publicado en 2012

Proteomic analysis of mitochondria in APOE transgenic mice and in response to an ischemic challenge

artículo científico publicado en 2012

Recent progress in translational research on neurovascular and neurodegenerative disorders

artículo científico publicado en 2017

Regionally selective and dose-dependent effects of the ampakines Org 26576 and Org 24448 on local cerebral glucose utilisation in the mouse as assessed by 14C-2-deoxyglucose autoradiography.

artículo científico publicado en 2005

Restoration of oligodendrocyte pools in a mouse model of chronic cerebral hypoperfusion

artículo científico publicado en 2014

Selective white matter pathology induces a specific impairment in spatial working memory

artículo científico publicado en 2010

Small vessels, dementia and chronic diseases - molecular mechanisms and pathophysiology. ⬇️

artículo científico publicado en 2018

Small vessels, dementia and chronic diseases-molecular mechanisms and pathophysiology.

artículo científico publicado en 2016

Synaptic NMDA receptor activity boosts intrinsic antioxidant defenses

artículo científico publicado en 2008

The effects of environmental enrichment on white matter pathology in a mouse model of chronic cerebral hypoperfusion ⬇️

artículo científico publicado en 2017

The human NACP/α-synuclein gene: chromosome assignment to 4q21.3–q22 and TaqI RFLP analysis ⬇️

artículo científico publicado el 20 de marzo de 1995

The subtype of GluN2 C-terminal domain determines the response to excitotoxic insults

artículo científico publicado en 2012

White matter degeneration in vascular and other ageing-related dementias

artículo científico publicado en 2017

White matter tract and glial-associated changes in 5-hydroxymethylcytosine following chronic cerebral hypoperfusion

artículo científico publicado en 2014

Lista de obras de Karen Horsburgh

4-Hydroxynonenal immunoreactivity is increased in human hippocampus after global ischemia.

4-Sodium phenyl butyric acid has both efficacy and counter-indicative effects in the treatment of Col4a1 disease

APOE epsilon3 gene transfer attenuates brain damage after experimental stroke

Activation of Nrf2-regulated glutathione pathway genes by ischemic preconditioning

Ageing causes prominent neurovascular dysfunction associated with loss of astrocytic contacts and gliosis.

Alterations in ApoE and ApoJ in relation to degeneration and regeneration in a mouse model of entorhinal cortex lesion.

Angiotensin II-inhibiting drugs have no effect on intraneuronal Aβ or oligomeric Aβ levels in a triple transgenic mouse model of Alzheimer's disease.

Angiotensin II-inhibition: effect on Alzheimer's pathology in the aged triple transgenic mouse.

ApoE isoform-specific regulation of regeneration in the peripheral nervous system

Apolipoprotein E and the CNS response to injury.

Astrocyte-specific overexpression of Nrf2 protects against optic tract damage and behavioural alterations in a mouse model of cerebral hypoperfusion

Axon-glial disruption: the link between vascular disease and Alzheimer's disease?

Chronic cerebral hypoperfusion alters amyloid-β peptide pools leading to cerebral amyloid angiopathy, microinfarcts and haemorrhages in Tg-SwDI mice

Chronic cerebral hypoperfusion: a key mechanism leading to vascular cognitive impairment and dementia. Closing the translational gap between rodent models and human vascular cognitive impairment and dementia

Controlled hypertension induces cerebrovascular and gene alterations in Cyp1a1-Ren2 transgenic rats.

Differential alterations in the expression and activity of matrix metalloproteinases 2 and 9 after transient cerebral ischemia in mice

Differential alterations of second messenger systems and cerebral glucose use following excitotoxic lesion of rat cerebral cortex ⬇️

Dimethyl fumarate improves white matter function following severe hypoperfusion: Involvement of microglia/macrophages and inflammatory mediators.

Effects of environmental enrichment on white matter glial responses in a mouse model of chronic cerebral hypoperfusion ⬇️

Endocytic pathway alterations in human hippocampus after global ischemia and the influence of APOE genotype

Estrogen is neuroprotective via an apolipoprotein E-dependent mechanism in a mouse model of global ischemia.

Extension of cerebral hypoperfusion and ischaemic pathology beyond MCA territory after intraluminal filament occlusion in C57Bl/6J mice

Focal increases in [3H]forskolin and [3H]phorbol 12,13-dibutyrate binding in the rat brain following lesions of the medial septum.

Forebrain mineralocorticoid receptor overexpression enhances memory, reduces anxiety and attenuates neuronal loss in cerebral ischaemia

Frontal white matter hyperintensities, clasmatodendrosis and gliovascular abnormalities in ageing and post-stroke dementia ⬇️

Gliovascular disruption and cognitive deficits in a mouse model with features of small vessel disease

Gradual cerebral hypoperfusion in spontaneously hypertensive rats induces slowly evolving white matter abnormalities and impairs working memory.

Hypertension fails to disrupt white matter integrity in young or aged Fisher (F44) Cyp1a1Ren2 transgenic rats

Impact of age on the cerebrovascular proteomes of wild-type and Tg-SwDI mice

Impaired neuronal plasticity in transgenic mice expressing human apolipoprotein E4 compared to E3 in a model of entorhinal cortex lesion.

Intracortical Glutamate Perfusionin VivoInduces Cellular Alterations in Specific Protein Kinase C Isoforms and Amyloid Precursor Protein

Intraventricular Infusion of Apolipoprotein E Ameliorates Acute Neuronal Damage after Global Cerebral Ischemia in Mice

Kindling-induced changes of protein kinase C levels in hippocampus and neocortex

Long-term cilostazol treatment reduces gliovascular damage and memory impairment in a mouse model of chronic cerebral hypoperfusion

MRI is a sensitive marker of subtle white matter pathology in hypoperfused mice

Marked alterations in the cellular localisation and levels of apolipoprotein E following acute subdural haematoma in rat.

Mild fluid percussion injury in mice produces evolving selective axonal pathology and cognitive deficits relevant to human brain injury

Mild oxidative stress activates Nrf2 in astrocytes, which contributes to neuroprotective ischemic preconditioning.

Minimal ischaemic neuronal damage and HSP70 expression in MF1 strain mice following bilateral common carotid artery occlusion.

Minocycline reduces microgliosis and improves subcortical white matter function in a model of cerebral vascular disease

Neuroprotection after transient global cerebral ischemia in Wld(s) mutant mice.

Neuroprotective effect of adenoviral-mediated gene transfer of TIMP-1 and -2 in ischemic brain injury.

Proteomic analysis of mitochondria in APOE transgenic mice and in response to an ischemic challenge

Proteomic analysis of mitochondria in APOE transgenic mice and in response to an ischemic challenge

Recent progress in translational research on neurovascular and neurodegenerative disorders

Regionally selective and dose-dependent effects of the ampakines Org 26576 and Org 24448 on local cerebral glucose utilisation in the mouse as assessed by 14C-2-deoxyglucose autoradiography.

Restoration of oligodendrocyte pools in a mouse model of chronic cerebral hypoperfusion

Selective white matter pathology induces a specific impairment in spatial working memory

Small vessels, dementia and chronic diseases - molecular mechanisms and pathophysiology. ⬇️

Small vessels, dementia and chronic diseases-molecular mechanisms and pathophysiology.

Synaptic NMDA receptor activity boosts intrinsic antioxidant defenses

The effects of environmental enrichment on white matter pathology in a mouse model of chronic cerebral hypoperfusion ⬇️

The human NACP/α-synuclein gene: chromosome assignment to 4q21.3–q22 and TaqI RFLP analysis ⬇️

The subtype of GluN2 C-terminal domain determines the response to excitotoxic insults

White matter degeneration in vascular and other ageing-related dementias

White matter tract and glial-associated changes in 5-hydroxymethylcytosine following chronic cerebral hypoperfusion