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Lista de obras de Robert Heyderman

837Early Goal Directed Therapy for Acute Bacterial Meningitis in Malawian Adults.

artículo científico publicado en 2014

845Prediction of Outcome from Adult Bacterial Meningitis in a High HIV Seroprevelence, Resource-Poor Setting Using a New Severity Scoring Tool, the Malawi Adult Meningitis Score (MAMS).

artículo científico publicado en 2014

A Perspective on Invasive Salmonella Disease in Africa

artículo científico publicado en 2015

A microfluidic system to study cytoadhesion of Plasmodium falciparum infected erythrocytes to primary brain microvascularendothelial cells

artículo científico publicado en 2011

A prospective longitudinal study of the clinical outcomes from cryptococcal meningitis following treatment induction with 800 mg oral fluconazole in Blantyre, Malawi

artículo científico publicado en 2013

A prospective study of mortality from cryptococcal meningitis following treatment induction with 1200 mg oral fluconazole in Blantyre, Malawi

artículo científico publicado en 2014

A reduction in adult blood stream infection and case fatality at a large African hospital following antiretroviral therapy roll-out

artículo científico publicado en 2014

Absence of mucosal immunity in the human upper respiratory tract to the commensal bacteria Neisseria lactamica but not pathogenic Neisseria meningitidis during the peak age of nasopharyngeal carriage.

artículo científico publicado en 2009

Acquisition of pneumococci specific effector and regulatory Cd4+ T cells localising within human upper respiratory-tract mucosal lymphoid tissue.

artículo científico publicado en 2011

Acute bacterial meningitis in adults

artículo científico publicado en 2016

Addition of flucytosine to fluconazole for the treatment of cryptococcal meningitis in Africa: a multi-country cost-effectiveness analysis

artículo científico publicado en 2020

Adjunctive Dexamethasone in HIV-Associated Cryptococcal Meningitis

artículo científico publicado en 2016

Adults with cerebral malaria do not have sensory evoked responses typical of deep general anaesthesia.

artículo científico publicado en 2000

Aetiology and Risk Factors for Mortality in an Adult Community-Acquired Pneumonia Cohort in Malawi

artículo científico publicado en 2019

Age Related Patterns of Disease and Mortality in Hospitalised Adults in Malawi

artículo científico publicado en 2017

Alteration in glycosaminoglycan metabolism and surface charge on human umbilical vein endothelial cells induced by cytokines, endotoxin and neutrophils

artículo científico publicado el 1 de agosto de 1992

Alveolar T-helper 17 responses to streptococcus pneumoniae are preserved in ART-untreated and treated HIV-infected Malawian adults

artículo científico publicado en 2017

Analysis of pathogen-host cell interactions in purpura fulminans: expression of capsule, type IV pili, and PorA by Neisseria meningitidis in vivo.

artículo científico publicado en 2002

Antibiotic choices for meningitis beyond the neonatal period ⬇️

artículo científico publicado el 1 de febrero de 1992

Antibiotic treatment of suspected neonatal meningitis.

artículo científico publicado en 1991

Antibody imaging to locate a placental site trophoblastic tumour following a complete hydatidiform mole

artículo científico publicado en 1989

Antifungal Combinations for Treatment of Cryptococcal Meningitis in Africa.

artículo científico publicado en 2018

Arterial ischemic stroke in HIV: Defining and classifying etiology for research studies

artículo científico publicado en 2016

Ascertaining the burden of invasive Salmonella disease in hospitalised febrile children aged under four years in Blantyre, Malawi

scientific article published on 17 July 2019

Assessment of the effect of candidate anti-inflammatory treatments on the interaction between meningococci and inflammatory cells in vitro in a whole blood model

scientific article published on 01 January 1996

Association of human leukocyte antigen alleles and nevirapine hypersensitivity in a Malawian HIV-infected population

artículo científico publicado en 2013

Asymptomatic HIV-infected individuals on antiretroviral therapy exhibit impaired lung CD4(+) T-cell responses to mycobacteria

artículo científico publicado en 2014

Auditory- and somatosensory-evoked potentials in cerebral malaria and anaesthesia: a comparison.

artículo científico publicado en 2002

Awareness of a hospital's antibiotic policy can be improved.

artículo científico publicado en 2000

Bacterial genome-wide association study of hyper-virulent pneumococcal serotype 1 identifies genetic variation associated with neurotropism

artículo científico publicado en 2020

Bacterial meningitis in Malawian adults, adolescents, and children during the era of antiretroviral scale-up and Haemophilus influenzae type b vaccination, 2000-2012.

artículo científico publicado en 2014

Bacterial meningitis in Malawian infants <2 months of age: etiology and susceptibility to World Health Organization first-line antibiotics

artículo científico publicado en 2014

Barriers to successful early infant diagnosis of HIV infection at primary care level in Malawi

artículo científico publicado en 2015

Benefits of enhanced infection prophylaxis at antiretroviral therapy initiation by cryptococcal antigen status

artículo científico publicado en 2020

Brain MRI and cognitive function seven years after surviving an episode of severe acute malnutrition in a cohort of Malawian children

artículo científico publicado en 2018

Brain swelling and death in children with cerebral malaria

artículo científico publicado en 2015

British HIV Association Guidelines on the Use of Vaccines in HIV-Positive Adults 2015.

artículo científico publicado en 2016

British HIV Association guidelines for immunization of HIV-infected adults 2008

artículo científico publicado en 2008

Bronchoalveolar CD4+ T cell responses to respiratory antigens are impaired in HIV-infected adults

artículo científico publicado en 2011

Burden of enteric fever at three urban sites in Africa and Asia: a multicentre population-based study

artículo científico publicado en 2021

CSF Levels of Elongation Factor Tu Is Associated With Increased Mortality in Malawian Adults With <i>Streptococcus pneumoniae</i> Meningitis

artículo científico publicado en 2020

CYP2B6 c.983T>C polymorphism is associated with nevirapine hypersensitivity in Malawian and Ugandan HIV populations

artículo científico publicado en 2014

Capture-recapture analysis and pneumococcal meningitis estimates in England

scientific article published on 01 January 2004

Central nervous system compartmentalization of HIV-1 subtype C variants early and late in infection in young children

artículo científico publicado en 2012

Cerebrospinal fluid transcriptional analyses reveals upregulation of IL-17, Type 1 interferon transcriptional pathways and neutrophil persistence genes associated with increased mortality from pneumococcal meningitis in adults:

artículo científico publicado en 2018

Challenges in reducing group B Streptococcus disease in African settings

artículo científico publicado en 2016

Changing Incidence of Invasive Pneumococcal Disease in Infants Less Than 90 Days of Age Before and After Introduction of the 13-Valent Pneumococcal Conjugate Vaccine in Blantyre, Malawi: A 14-Year Hospital Based Surveillance Study

scientific article published in 2022

Changing epidemiology of bacterial meningitis among adults in England and Wales 1991-2002

article

Chronic Household Air Pollution Exposure Is Associated with Impaired Alveolar Macrophage Function in Malawian Non-Smokers

artículo científico publicado en 2015

Chronic disease outcomes after severe acute malnutrition in Malawian children (ChroSAM): a cohort study.

artículo científico publicado en 2016

Circulating microparticles are increased amongst people presenting with HIV and advanced immune suppression in Malawi and correlate closely with arterial stiffness: a nested case control study

artículo científico publicado en 2022

Clinical management of urinary tract infection in women: a prospective cohort study

artículo científico publicado en 2003

Clinical manifestations of nontuberculous mycobacteria.

artículo científico publicado en 2006

Community-acquired acute bacterial meningitis in adults: a clinical update

artículo científico publicado en 2019

Comparative Genomic Analysis of Meningitis- and Bacteremia-Causing Pneumococci Identifies a Common Core Genome

artículo científico publicado en 2015

Comparison and Correlation of Serogroup B Immunologic Assay Results and Human Antibody Responses following Three Doses of the Norwegian Meningococcal Outer Membrane Vesicle Vaccine MenBvac

scientific article published in 2007

Comparison and correlation of neisseria meningitidis serogroup B immunologic assay results and human antibody responses following three doses of the Norwegian meningococcal outer membrane vesicle vaccine MenBvac

artículo científico publicado en 2006

Corrigendum to "The UK joint specialist societies guideline on the diagnosis and management of acute meningitis and meningococcal sepsis in immunocompetent Adults" [J Infect 72 (2016) 405-438].

artículo científico publicado en 2016

Cost-Effectiveness of Monovalent Rotavirus Vaccination of Infants in Malawi: A Postintroduction Analysis Using Individual Patient-Level Costing Data

artículo científico publicado en 2016

Critical determinants of the interactions of capsule-expressing Neisseria meningitidis with host cells: the role of receptor density in increased cellular targeting via the outer membrane Opa proteins.

artículo científico publicado en 2005

Cross-sectional health centre and community-based evaluation of the impact of pneumococcal and malaria vaccination on antibiotic prescription and usage, febrile illness and antimicrobial resistance in young children in Malawi: the IVAR study protoco

artículo científico publicado en 2023

CryptoDex: a randomised, double-blind, placebo-controlled phase III trial of adjunctive dexamethasone in HIV-infected adults with cryptococcal meningitis: study protocol for a randomised control trial

artículo científico publicado en 2014

Current concepts in the treatment of bacterial meningitis beyond the neonatal period.

artículo científico publicado en 2006

Defective pneumococcal-specific Th1 responses in HIV-infected adults precedes a loss of control of pneumococcal colonization

artículo científico publicado en 2012

Delayed reconstitution of B cell immunity to pneumococcus in HIV-infected Malawian children on antiretroviral therapy

artículo científico publicado en 2014

Detection of fibronectin expression by human endothelial cells using a enzyme-linked immunosorbent assay (ELISA): enzymatic degradation by activated plasminogen

scientific article published on 01 March 1997

Detection of glycosaminoglycans on the surface of human umbilical vein endothelial cells using gold-conjugated poly-L-lysine with silver enhancement

artículo científico publicado en 1993

Detection of herpes viruses in the cerebrospinal fluid of adults with suspected viral meningitis in Malawi.

artículo científico publicado en 2012

Detection of tuberculosis in HIV-infected and -uninfected African adults using whole blood RNA expression signatures: a case-control study

artículo científico publicado en 2013

Deteriorating pneumococcal-specific B-cell memory in minimally symptomatic African children with HIV infection

artículo científico publicado en 2011

Determination of a Viral Load Threshold To Distinguish Symptomatic versus Asymptomatic Rotavirus Infection in a High-Disease-Burden African Population.

artículo científico publicado en 2015

Diagnosis of childhood tuberculosis and host RNA expression in Africa

artículo científico publicado en 2014

Direct and possible indirect effects of vaccination on rotavirus hospitalisations among children in Malawi four years after programmatic introduction

artículo científico publicado en 2018

Disseminated intravascular coagulation and purpura fulminans secondary to infection

article

Distinct Salmonella Enteritidis lineages associated with enterocolitis in high-income settings and invasive disease in low-income settings

artículo científico publicado en 2016

Do multiple concurrent infections in African children cause irreversible immunological damage?

artículo científico

Domestic River Water Use and Risk of Typhoid Fever: Results From a Case-control Study in Blantyre, Malawi

artículo científico publicado en 2020

Drug resistance in Salmonella enterica ser. Typhimurium bloodstream infection, Malawi.

artículo científico publicado en 2014

Dysfunction of Endothelial Protein C Activation in Severe Meningococcal Sepsis

article

Dysregulation of coagulation in cerebral malaria.

artículo científico publicado en 2009

Early Antiretroviral Therapy Initiation and Mortality Among Infants Diagnosed With HIV in the First 12 Weeks of Life: Experiences From Kinshasa, DR Congo and Blantyre, Malawi

artículo científico publicado en 2017

Early T Cell Differentiation with Well-Maintained Function across the Adult Life Course in Sub-Saharan Africa

scientific article published on 29 July 2019

Early deaths during tuberculosis treatment are associated with depressed innate responses, bacterial infection, and tuberculosis progression

artículo científico publicado en 2011

Early management of suspected bacterial meningitis and meningococcal septicaemia in immunocompetent adults--second edition.

artículo científico publicado en 2005

Early signals of vaccine driven perturbation seen in pneumococcal carriage population genomic data

article

Effect of oral fluconazole 1200 mg/day on QT interval in African adults with HIV-associated cryptococcal meningitis

article

Effectiveness of a monovalent rotavirus vaccine in infants in Malawi after programmatic roll-out: an observational and case-control study

artículo científico publicado en 2015

Electronic data capture for large scale typhoid surveillance, household contact tracing, and health utilisation survey: Strategic Typhoid Alliance across Africa and Asia

scientific article published on 09 April 2020

Emergence of double- and triple-gene reassortant G1P[8] rotaviruses possessing a DS-1-like backbone post rotavirus vaccine introduction in Malawi

artículo científico publicado en 2017

Emerging resistance to empiric antimicrobial regimens for pediatric bloodstream infections in Malawi (1998-2017)

article

Epidemic multiple drug resistant Salmonella Typhimurium causing invasive disease in sub-Saharan Africa have a distinct genotype

artículo científico publicado en 2009

Epidemics of invasive Salmonella enterica serovar enteritidis and S. enterica Serovar typhimurium infection associated with multidrug resistance among adults and children in Malawi

artículo científico publicado en 2008

Epidemiology of Severe Acute Respiratory Illness and Risk Factors for Influenza Infection and Clinical Severity among Adults in Malawi, 2011-2013

artículo científico publicado en 2018

Epithelial control of colonisation byStreptococcus pneumoniaeat the human mucosal surface

artículo científico publicado en 2018

Epstein-barr virus coinfection in cerebrospinal fluid is associated with increased mortality in Malawian adults with bacterial meningitis.

artículo científico publicado en 2011

Erratum for Kulohoma et al., Comparative genomic analysis of meningitis- and bacteremia-causing pneumococci identifies a common core genome

artículo científico publicado en 2015

Erratum: Distinct Salmonella Enteritidis lineages associated with enterocolitis in high-income settings and invasive disease in low-income settings

artículo científico publicado en 2017

Evaluating the reactivation of herpesviruses and inflammation as cardiovascular and cerebrovascular risk factors in antiretroviral therapy initiators in an African HIV-infected population (RHICCA): a protocol for a longitudinal cohort study

artículo científico publicado en 2019

Evaluation of Xpert MTB/RIF for detection of tuberculosis from blood samples of HIV-infected adults confirms Mycobacterium tuberculosis bacteremia as an indicator of poor prognosis

artículo científico publicado en 2013

Evaluation of pneumococcal serotyping in nasopharyngeal carriage isolates by latex agglutination, whole genome sequencing (PneumoCaT) and DNA microarray in a high pneumococcal carriage prevalence population in Malawi

artículo científico publicado en 2020

Evidence for Naturally Acquired T Cell-Mediated Mucosal Immunity to Neisseria meningitidis ⬇️

artículo científico publicado el 15 de octubre de 2003

Genetic characterisation of Malawian pneumococci prior to the roll-out of the PCV13 vaccine using a high-throughput whole genome sequencing approach

artículo científico publicado en 2012

Genome-wide association study of nevirapine hypersensitivity in a sub-Saharan African HIV-infected population

artículo científico publicado en 2017

Genomic analysis of Klebsiella pneumoniae isolates from Malawi reveals acquisition of multiple ESBL determinants across diverse lineages

scientific article published on 01 May 2019

Genomic identification of a novel co-trimoxazole resistance genotype and its prevalence amongst Streptococcus pneumoniae in Malawi.

artículo científico publicado en 2013

Genomic landscape of extended-spectrum β-lactamase resistance in Escherichia coli from an urban African setting

artículo científico publicado en 2017

Genotypic homogeneity of multidrug resistant S. Typhimurium infecting distinct adult and childhood susceptibility groups in Blantyre, Malawi

artículo científico publicado en 2012

Goal directed therapy for suspected acute bacterial meningitis in adults and adolescents in sub-Saharan Africa

artículo científico publicado en 2017

Group B streptococcus vaccination in pregnant women with or without HIV in Africa: a non-randomised phase 2, open-label, multicentre trial

artículo científico publicado en 2016

HIV coinfection influences the inflammatory response but not the outcome of cerebral malaria in Malawian children

artículo científico publicado en 2016

HIV, antiretroviral treatment, hypertension, and stroke in Malawian adults: A case-control study.

artículo científico publicado en 2015

HIV-associated disruption of lung cytokine networks is incompletely restored in asymptomatic HIV-infected Malawian adults on antiretroviral therapy

artículo científico publicado en 2017

HIV-exposed uninfected children: a growing population with a vulnerable immune system?

artículo científico

HIV-related arterial stiffness in Malawian adults is associated with proportion of PD-1 expressing CD8 T-cells and reverses with anti-retroviral therapy

article

Haemolytic-uraemic syndrome

scientific article published on 01 April 1994

Healthcare Costs and Life-years Gained From Treatments Within the Advancing Cryptococcal Meningitis Treatment for Africa (ACTA) Trial on Cryptococcal Meningitis: A Comparison of Antifungal Induction Strategies in Sub-Saharan Africa

artículo científico publicado en 2019

High mortality amongst adolescents and adults with bacterial meningitis in sub-Saharan Africa: an analysis of 715 cases from Malawi

artículo científico publicado en 2013

High multiple carriage and emergence of Streptococcus pneumoniae vaccine serotype variants in Malawian children.

artículo científico publicado en 2015

High prevalence of tuberculosis and serious bloodstream infections in ambulatory individuals presenting for antiretroviral therapy in Malawi

artículo científico publicado en 2012

High residual carriage of vaccine-serotype Streptococcus pneumoniae after introduction of pneumococcal conjugate vaccine in Malawi

artículo científico publicado en 2020

High residual prevalence of vaccine serotype Streptococcus pneumoniae carriage 4 to 6 years after introduction of 13-valent pneumococcal conjugate vaccine in Malawi: a prospective serial cross-sectional study

artículo científico publicado en 2018

Household air pollution and the lung microbiome of healthy adults in Malawi: a cross-sectional study

artículo científico publicado en 2016

Household air pollution causes dose-dependent inflammation and altered phagocytosis in human macrophages

artículo científico publicado en 2015

How Does Blood-Retinal Barrier Breakdown Relate to Death and Disability in Pediatric Cerebral Malaria?

artículo científico publicado en 2020

Human SARS-CoV-2 challenge uncovers local and systemic response dynamics

artículo científico publicado en 2024

Human immunodeficiency virus (HIV) infection during pregnancy induces CD4 T-cell differentiation and modulates responses to Bacille Calmette-Guérin (BCG) vaccine in HIV-uninfected infants

artículo científico publicado en 2009

Human melioidosis, Malawi, 2011.

artículo científico publicado en 2013

Human papillomavirus and head and neck cancer: a systematic review and meta-analysis.

artículo científico publicado en 2006

Human tonsil-derived dendritic cells are poor inducers of T cell immunity to mucosally encountered pathogens

artículo científico publicado en 2013

IFN-gamma amplifies NFkappaB-dependent Neisseria meningitidis invasion of epithelial cells via specific upregulation of CEA-related cell adhesion molecule 1.

artículo científico publicado en 2007

Identification of a common immune signature in murine and human systemic Salmonellosis

artículo científico publicado en 2012

Identifying Streptococcus pneumoniae genes associated with invasive disease using pangenome-based whole genome sequence typing

artículo científico publicado en 2018

Identifying genes associated with invasive disease in S. pneumoniae by applying a machine learning approach to whole genome sequence typing data

article

Immunoglobulin G subclass response to a meningococcal quadrivalent polysaccharide-diphtheria toxoid conjugate vaccine

artículo científico publicado en 2006

Impact and Effectiveness of 13-Valent Pneumococcal Conjugate Vaccine on Population Incidence of Vaccine and Non-Vaccine Serotype Invasive Pneumococcal Disease in Blantyre, Malawi, 2006-2018: Prospective Observational Time-Series and Case-Control Stu

scientific article published in 2020

Impact and effectiveness of 13-valent pneumococcal conjugate vaccine on population incidence of vaccine and non-vaccine serotype invasive pneumococcal disease in Blantyre, Malawi, 2006–18: prospective observational time-series and case-control studi

scientific article published in 2021

Impact of Human Immunodeficiency Virus on the Burden and Severity of Influenza Illness in Malawian Adults: A Prospective Cohort and Parallel Case-Control Study

artículo científico publicado en 2017

Impact of Maternal HIV Infection and Placental Malaria on the Transplacental Transfer of Influenza Antibodies in Mother-Infant Pairs in Malawi, 2013-2014

scientific article published on 28 August 2019

Impact of monovalent rotavirus vaccine on diarrhoea-associated post-neonatal infant mortality in rural communities in Malawi: a population-based birth cohort study

artículo científico publicado en 2018

Impaired CD4 T cell memory response to Streptococcus pneumoniae precedes CD4 T cell depletion in HIV-infected Malawian adults

artículo científico publicado en 2011

Impaired maintenance of naturally acquired T-cell memory to the meningococcus in patients with B-cell immunodeficiency.

artículo científico publicado en 2009

Impairment of pneumococcal antigen specific isotype-switched Igg memory B-cell immunity in HIV infected Malawian adults

artículo científico publicado en 2013

Implementing early infant diagnosis of HIV infection at the primary care level: experiences and challenges in Malawi

artículo científico publicado en 2012

Improving recognition of severe illness and patient pathways in primary health services using mHealth technology in urban Blantyre, Malawi

artículo científico publicado en 2013

Incomplete recovery of pneumococcal CD4 T cell immunity after initiation of antiretroviral therapy in HIV-infected malawian adults

artículos científicos

Infectious diseases

scientific article published on 01 April 1991

Inflammatory Phenotypes Predict Changes in Arterial Stiffness following ART Initiation

artículo científico publicado en 2020

Influence of age and carriage status on salivary IgA to Neisseria meningitidis

artículo científico publicado en 2005

Influenza-like illness is associated with high pneumococcal carriage density in Malawian children

artículo científico publicado en 2020

Infrequent Transmission of Monovalent Human Rotavirus Vaccine Virus to Household Contacts of Vaccinated Infants in Malawi

article

Innate and adaptive nasal mucosal immune responses following experimental human pneumococcal colonization

artículo científico publicado en 2019

Interactions of Meningococci with Endothelium

artículo científico publicado el 1 de enero de 2001

Intestinal Perforations Associated With a High Mortality and Frequent Complications During an Epidemic of Multidrug-resistant Typhoid Fever in Blantyre, Malawi

artículo científico publicado en 2020

Intracontinental spread of human invasive Salmonella Typhimurium pathovariants in sub-Saharan Africa

artículo científico publicado en 2012

Invasive Salmonella Discussed in Africa Consensus Meeting 2014, Blantyre, Malawi. ⬇️

artículo científico publicado en 2015

Invasive Salmonella infections in Africa

artículo científico publicado en 2014

Invasive non-typhoid salmonellae establish systemic intracellular infection in HIV-infected adults: an emerging disease pathogenesis

artículo científico publicado en 2010

Invasive non-typhoidal salmonella disease: an emerging and neglected tropical disease in Africa.

artículo científico publicado en 2012

Invasiveness potential of pneumococcal serotypes in children after introduction of PCV13 in Blantyre, Malawi

artículo científico publicado en 2023

Ischemic stroke as a complication of cryptococcal meningitis and immune reconstitution inflammatory syndrome: a case report

artículo científico publicado en 2018

Kinetics of Mycobacterium tuberculosis-specific IFN-γ responses and sputum bacillary clearance in HIV-infected adults during treatment of pulmonary tuberculosis

artículo científico publicado en 2015

Laboratory evidence of disseminated intravascular coagulation is associated with a fatal outcome in children with cerebral malaria despite an absence of clinically evident thrombosis or bleeding

artículo científico publicado en 2015

Lack of decline in childhood malaria, Malawi, 2001-2010.

artículo científico publicado en 2012

Leave no one behind: response to new evidence and guidelines for the management of cryptococcal meningitis in low-income and middle-income countries

scholarly article by Angela Loyse et al published 18 October 2018 in Lancet Infectious Diseases

Long-term effects of severe acute malnutrition on lung function in Malawian children: a cohort study

artículo científico publicado en 2017

Longitudinal lactate levels from routine point-of-care monitoring in adult Malawian antiretroviral therapy patients: associations with stavudine toxicities

artículo científico publicado en 2013

Loss of Humoral and Cellular Immunity to Invasive Nontyphoidal Salmonella during Current or Convalescent Plasmodium falciparum Infection in Malawian Children ⬇️

artículo científico publicado en 2017

Loss of Multicellular Behavior in Epidemic African Nontyphoidal Salmonella enterica Serovar Typhimurium ST313 Strain D23580.

artículo científico publicado en 2016

Loss of endothelial protein C receptors links coagulation and inflammation to parasite sequestration in cerebral malaria in African children

artículo científico publicado en 2013

Lumbar puncture in the management of adults with suspected bacterial meningitis--a survey of practice.

artículo científico publicado en 2005

Management of diagnostic uncertainty in children with possible meningitis: a qualitative study ⬇️

artículo científico publicado el 1 de agosto de 2003

Management of meningococcal infections.

artículo científico publicado en 1993

Management of severe non-TB bacterial infection in HIV-infected adults

artículo científico

Managing acute cystitis in women

artículo científico publicado en 2004

Mathematical Modeling to Assess the Drivers of the Recent Emergence of Typhoid Fever in Blantyre, Malawi

artículo científico publicado en 2015

Methodological challenges in measuring vaccine effectiveness using population cohorts in low resource settings

artículo científico publicado en 2015

Methods and challenges in measuring the impact of national pneumococcal and rotavirus vaccine introduction on morbidity and mortality in Malawi

artículo científico publicado en 2015

Microinvasion by Streptococcus pneumoniae induces epithelial innate immunity during colonisation at the human mucosal surface

scientific article published on 16 July 2019

Modelling the Contributions of Malaria, HIV, Malnutrition and Rainfall to the Decline in Paediatric Invasive Non-typhoidal Salmonella Disease in Malawi

artículo científico publicado en 2015

Modulation of the endothelial procoagulant response to lipopolysaccharide and tumour necrosis factor-alpha in-vitro: the effects of dexamethasone, pentoxifylline, iloprost and a polyclonal anti-human IL-1 alpha antibody

artículo científico publicado en 1995

Molecular Surveillance Identifies Multiple Transmissions of Typhoid in West Africa

artículo científico publicado en 2016

Monocyte unresponsiveness and impaired IL1β, TNFα and IL7 production are associated with a poor outcome in Malawian adults with pulmonary tuberculosis

artículo científico publicado en 2015

Mucosal immunity and optimizing protection with meningococcal serogroup B vaccines

artículo científico publicado en 2006

Mucosal immunity in healthy adults after parenteral vaccination with outer-membrane vesicles from Neisseria meningitidis serogroup B

artículo científico publicado en 2008

Mucosal immunity in resource-limited setting: is the battle ground different?

artículo científico publicado en 2010

Multiplex Real-Time PCR Detection of Intestinal Protozoa in HIV-Infected Children in Malawi, Enterocytozoon Bieneusi is Common and Associated with Gastrointestinal Complaints and May Delay BMI (Nutritional Status) Recovery.

artículo científico publicado en 2018

Naturally-acquired influenza-specific CD4+ T-cell proliferative responses are impaired in HIV-infected African adults

artículo científico publicado en 2012

Neisseria lactamica selectively induces mitogenic proliferation of the naive B cell pool via cell surface Ig.

artículo científico publicado en 2010

Neutrophil response to Neisseria meningitidis: inhibition of adhesion molecule expression and phagocytosis by recombinant bactericidal/permeability-increasing protein (rBPI21)

artículo científico publicado en 1999

Non-secretor histo-blood group antigen phenotype is associated with reduced risk of clinical rotavirus vaccine failure in Malawian infants

artículo científico publicado en 2019

Omicron B.1.1.529 variant infections associated with severe disease are uncommon in a COVID-19 under-vaccinated, high SARS-CoV-2 seroprevalence population in Malawi

artículo científico publicado en 2023

One-year Mortality Outcomes From the Advancing Cryptococcal Meningitis Treatment for Africa Trial of Cryptococcal Meningitis Treatment in Malawi

artículo científico publicado en 2020

Osmotic therapies added to antibiotics for acute bacterial meningitis

artículo científico publicado en 2013

Osmotic therapies added to antibiotics for acute bacterial meningitis.

artículo científico publicado en 2018

Osmotic therapies as adjuncts to antibiotics for acute bacterial meningitis

artículo científico publicado en 2010

Pan-GWAS of Streptococcus agalactiae Highlights Lineage-Specific Genes Associated with Virulence and Niche Adaptation

artículo científico publicado en 2020

Parenteral influenza vaccination influences mucosal and systemic T cell-mediated immunity in healthy adults

artículo científico publicado en 2004

Performance of HIV Rapid Tests Among Breastfeeding, Malawian Infants

artículo científico publicado en 2016

Persistent endothelial activation and inflammation after Plasmodium falciparum Infection in Malawian children

artículo científico publicado en 2013

Pharmacodynamic Modeling of Bacillary Elimination Rates and Detection of Bacterial Lipid Bodies in Sputum to Predict and Understand Outcomes in Treatment of Pulmonary Tuberculosis

artículo científico publicado en 2015

Phenotypic Correlates of HIV-1 Macrophage Tropism

artículo científico publicado en 2015

Phylogeographical analysis of the dominant multidrug-resistant H58 clade of Salmonella Typhi identifies inter- and intracontinental transmission events

artículo científico publicado en 2015

Piliation of invasive Streptococcus pneumoniae isolates in the era before pneumococcal conjugate vaccine introduction in Malawi ⬇️

artículo científico publicado en 2013

Platelet and soluble CD40L in meningococcal sepsis.

artículo científico publicado en 2006

Platelet satellitism

artículo científico publicado en 1998

Pleural tuberculosis in Harare, Zimbabwe: the relationship between human immunodeficiency virus, CD4 lymphocyte count, granuloma formation and disseminated disease.

artículo científico publicado en 1998

Pneumococcal pneumonia and carriage in Africa before and after introduction of pneumococcal conjugate vaccines, 2000-2019: protocol for systematic review

artículo científico publicado en 2019

Polysaccharide-specific memory B cells generated by conjugate vaccines in humans conform to the CD27+IgG+ isotype-switched memory B Cell phenotype and require contact-dependent signals from bystander T cells activated by bacterial proteins to differ

artículo científico publicado en 2013

Population Impact and Effectiveness of Monovalent Rotavirus Vaccination in Urban Malawian Children 3 Years After Vaccine Introduction: Ecological and Case-Control Analyses

artículo científico publicado en 2016

Population genetic structure, antibiotic resistance, capsule switching and evolution of invasive pneumococci before conjugate vaccination in Malawi ⬇️

artículo científico publicado en 2017

Population pharmacokinetic and pharmacogenetic analysis of nevirapine in hypersensitive and tolerant HIV-infected patients from Malawi

artículo científico publicado en 2013

Population pharmacokinetic and pharmacogenetic analysis of nevirapine in hypersensitive and tolerant HIV-infected patients from Malawi

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Postinfectious purpura fulminans caused by an autoantibody directed against protein S ⬇️

artículo científico publicado el 1 de septiembre de 1995

Potential role for mucosally active vaccines against pneumococcal pneumonia

artículo científico publicado en 2009

Preclinical Development of Virulence Attenuated <i>Streptococcus pneumoniae</i> Strains Able to Enhance Protective Immunity Against Pneumococcal Infection

artículo científico publicado en 2020

Prediction of Outcome From Adult Bacterial Meningitis in a High-HIV-Seroprevalence, Resource-Poor Setting Using the Malawi Adult Meningitis Score (MAMS).

artículo científico publicado en 2016

Predictive value of C-reactive protein for tuberculosis, bloodstream infection or death among HIV-infected individuals with chronic, non-specific symptoms and negative sputum smear microscopy.

artículo científico publicado en 2017

Predictors of Uptake and Timeliness of Newly Introduced Pneumococcal and Rotavirus Vaccines, and of Measles Vaccine in Rural Malawi: A Population Cohort Study

artículo científico publicado en 2016

Prevalence and spectrum of illness among hospitalized adults with malaria in Blantyre, Malawi

artículo científico publicado en 2014

Prostacyclin concentrations in haemolytic uraemic syndrome after acute shigellosis.

artículo científico publicado en 1992

Public engagement in Malawi through a health-talk radio programme 'Umoyo nkukambirana': A mixed-methods evaluation

artículo científico publicado en 2016

Pulmonary tuberculosis in Harare, Zimbabwe: analysis by spoligotyping.

artículo científico publicado en 1998

Quality of in-hospital care for adults with acute bacterial meningitis: a national retrospective survey.

artículo científico publicado en 2006

Raltegravir-intensified initial antiretroviral therapy in advanced HIV disease in Africa: A randomised controlled trial

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Rapid emergence of multidrug resistant, H58-lineage Salmonella typhi in Blantyre, Malawi.

artículo científico publicado en 2015

Rapid emergence of resistance to penicillin and trimethoprim-sulphamethoxazole in invasive Streptococcus pneumoniae in Zimbabwe.

artículo científico publicado en 2003

Re: Moxifloxacin should not be discounted in the treatment of bacterial meningitis

artículo científico publicado en 2016

Recognising and treatment seeking for acute bacterial meningitis in adults and children in resource-poor settings: a qualitative study

artículo científico publicado en 2013

Recombination in Streptococcus pneumoniae Lineages Increase with Carriage Duration and Size of the Polysaccharide Capsule

artículo científico publicado en 2016

Reduction of the anticoagulant activity of glycosaminoglycans on the surface of the vascular endothelium by endotoxin and neutrophils: evaluation by an amidolytic assay

artículo científico publicado el 15 de septiembre de 1992

Region-specific diversification of the highly virulent serotype 1 Streptococcus pneumoniae

artículo científico publicado en 2015

Regulation of Th-1 T cell-dominated immunity to Neisseria meningitidis within the human mucosa

artículo científico publicado en 2006

Regulation of naturally acquired mucosal immunity to Streptococcus pneumoniae in healthy Malawian adults and children

artículo científico publicado en 2012

Respiratory Virus-Associated Severe Acute Respiratory Illness and Viral Clustering in Malawian Children in a Setting With a High Prevalence of HIV Infection, Malaria, and Malnutrition

artículo científico publicado en 2016

Respiratory research funding is inadequate, inequitable, and a missed opportunity

artículo científico publicado en 2020

Risk factors for pneumococcal carriage in adults living with HIV on antiretroviral therapy in the infant pneumococcal vaccine era in Malawi

artículo científico publicado en 2022

Safety and immunogenicity of a typhoid conjugate vaccine among children aged 9 months to 12 years in Malawi: a nested substudy of a double-blind, randomised controlled trial

artículo científico publicado en 2022

Sepsis and intravascular thrombosis.

artículo científico publicado en 1993

Sepsis carries a high mortality among hospitalised adults in Malawi in the era of antiretroviral therapy scale-up: a longitudinal cohort study

artículo científico publicado en 2014

Sequential acquisition of T cells and antibodies to nontyphoidal Salmonella in Malawian children

artículo científico publicado en 2014

Severe Acute Respiratory Illness Deaths in Sub-Saharan Africa and the Role of Influenza: A Case Series From 8 Countries

artículo científico publicado en 2015

Severe meningococcal disease is characterized by early neutrophil but not platelet activation and increased formation and consumption of platelet-neutrophil complexes.

artículo científico publicado en 2003

Severe toxicity and polymerase-γ gene abnormalities in Malawian adults on stavudine-based antiretroviral therapy

artículo científico publicado en 2013

Six-month mortality among HIV-infected adults presenting for antiretroviral therapy with unexplained weight loss, chronic fever or chronic diarrhea in Malawi.

artículo científico publicado en 2012

Small alveolar macrophages are infected preferentially by HIV and exhibit impaired phagocytic function

artículo científico publicado en 2014

Social mixing patterns relevant to infectious diseases spread by close contact in urban Blantyre, Malawi

artículo científico publicado en 2022

Spinal anesthesia with an indwelling catheter reduces the stress response in pediatric open heart surgery.

artículo científico publicado en 2005

Stavudine toxicity in adult longer-term ART patients in Blantyre, Malawi

artículo científico publicado en 2012

Streptococcal Serine-Rich Repeat Proteins in Colonization and Disease

artículo científico publicado en 2020

Study protocol: the effects of air pollution exposure and chronic respiratory disease on pneumonia risk in urban Malawian adults--the Acute Infection of the Respiratory Tract Study (The AIR Study).

artículo científico publicado en 2015

Suboptimal patterns of provider initiated HIV testing and counselling, antiretroviral therapy eligibility assessment and referral in primary health clinic attendees in Blantyre, Malawi

artículo científico publicado en 2012

Surveillance Programme of IN-patients and Epidemiology (SPINE): implementation of an electronic data collection tool within a large hospital in Malawi

artículo científico publicado en 2013

Sustained reduction in third-generation cephalosporin usage in adult inpatients following introduction of an antimicrobial stewardship program in a large urban hospital in Malawi

artículo científico publicado en 2020

T cell memory response to pneumococcal protein antigens in an area of high pneumococcal carriage and disease

artículo científico publicado en 2009

T-Regulatory Cells and Inflammatory and Inhibitory Cytokines in Malawian Children Residing in an Area of High and an Area of Low Malaria Transmission During Acute Uncomplicated Malaria and in Convalescence

artículo científico publicado en 2015

Ten years of surveillance for invasive Streptococcus pneumoniae during the era of antiretroviral scale-up and cotrimoxazole prophylaxis in Malawi ⬇️

artículo científico publicado en 2011

The Global Meningitis Genome Partnership

artículo científico publicado en 2020

The Role of Human Immunodeficiency Virus-Associated Vasculopathy in the Etiology of Stroke

artículo científico publicado en 2017

The STRATAA study protocol: a programme to assess the burden of enteric fever in Bangladesh, Malawi and Nepal using prospective population census, passive surveillance, serological studies and healthcare utilisation surveys

artículo científico publicado en 2017

The Surveillance for Enteric Fever in Asia Project (SEAP), Severe Typhoid Fever Surveillance in Africa (SETA), Surveillance of Enteric Fever in India (SEFI), and Strategic Typhoid Alliance Across Africa and Asia (STRATAA) Population-based Enteric Fe

artículo científico publicado en 2020

The Treatment of Possible Severe Infection in Infants: An Open Randomized Safety Trial of Parenteral Benzylpenicillin and Gentamicin Versus Ceftriaxone in Infants <60 days of Age in Malawi

artículo científico publicado en 2017

The Typhoid Vaccine Acceleration Consortium (TyVAC): Vaccine effectiveness study designs: Accelerating the introduction of typhoid conjugate vaccines and reducing the global burden of enteric fever. Report from a meeting held on 26–27 October 2016,

artículo científico publicado en 2017

The UK joint specialist societies guideline on the diagnosis and management of acute meningitis and meningococcal sepsis in immunocompetent adults.

artículo científico publicado en 2016

The UK's Global Health Respiratory Network: Improving respiratory health of the world's poorest through research collaborations

artículo científico publicado en 2019

The challenges of managing severe dehydrating diarrhoea in a resource-limited setting

artículo científico

The diagnostic and prognostic accuracy of five markers of serious bacterial infection in Malawian children with signs of severe infection

artículo científico publicado en 2009

The economic impact of childhood acute gastroenteritis on Malawian families and the healthcare system

artículo científico publicado en 2017

The effect of HIV infection and exposure on cognitive development in the first two years of life in Malawi

scientific article published on 21 November 2019

The global distribution and diversity of protein vaccine candidate antigens in the highly virulent Streptococcus pnuemoniae serotype 1.

artículo científico publicado en 2017

The histone demethylase KDM6B fine-tunes the host response to Streptococcus pneumoniae

scientific article published on 21 December 2020

The human transcriptome during nontyphoid Salmonella and HIV coinfection reveals attenuated NFkappaB-mediated inflammation and persistent cell cycle disruption

artículo científico publicado en 2011

The influence of capsulation and lipooligosaccharide structure on neutrophil adhesion molecule expression and endothelial injury by Neisseria meningitidis

artículo científico publicado en 1996

The macrophage marches on its phagosome: dynamic assays of phagosome function.

artículo científico publicado en 2009

The role of angiogenic factors in predicting clinical outcome in severe bacterial infection in Malawian children

artículo científico publicado en 2010

Three Epidemics of Invasive Multidrug-Resistant Salmonella Bloodstream Infection in Blantyre, Malawi, 1998-2014.

artículo científico publicado en 2015

Tonsil T cell immunity to human papillomavirus in the absence of detectable virus in healthy adults

artículo científico publicado en 2008

Transfusion and Treatment of severe anaemia in African children (TRACT): a study protocol for a randomised controlled trial

artículo científico publicado en 2015

Trends in antimicrobial resistance in bloodstream infection isolates at a large urban hospital in Malawi (1998-2016): a surveillance study

artículo científico publicado en 2017

Typhoid Vaccine Acceleration Consortium Malawi: A Phase III, Randomized, Double-blind, Controlled Trial of the Clinical Efficacy of Typhoid Conjugate Vaccine Among Children in Blantyre, Malawi

artículo científico publicado en 2019

Typhoid conjugate vaccine effectiveness in Malawi: evaluation of a test-negative design using randomised, controlled clinical trial data

artículo científico publicado en 2023

Typhoid fever and invasive nontyphoid salmonellosis, Malawi and South Africa ⬇️

artículo científico publicado en 2010

Understanding pneumococcal serotype 1 biology through population genomic analysis

artículo científico publicado en 2016

Unstructured treatment interruption: an important risk factor for arterial stiffness in adult Malawian patients with antiretroviral treatment

artículo científico publicado en 2016

Vaccine Effectiveness against DS-1-Like Rotavirus Strains in Infants with Acute Gastroenteritis, Malawi, 2013-2015

scientific article published on 01 September 2019

Validity of US norms for the Bayley Scales of Infant Development-III in Malawian children

artículo científico publicado en 2013

Variation in reported neonatal group B streptococcal disease incidence in developing countries

artículo científico publicado en 2012

Waning of antibody levels induced by a 13-valent pneumococcal conjugate vaccine, using a 3 + 0 schedule, within the first year of life among children younger than 5 years in Blantyre, Malawi: an observational, population-level, serosurveillance stud

artículo científico publicado en 2022

When enough is enough: how the decision was made to stop the FEAST trial: data and safety monitoring in an African trial of Fluid Expansion As Supportive Therapy (FEAST) for critically ill children

artículo científico publicado en 2013

Whole blood model of meningococcal bacteraemia--a method for exploring host-bacterial interactions

scientific article published on 01 February 1995

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