Lista de obras -

A Brain Tumor/Organotypic Slice Co-culture System for Studying Tumor Microenvironment and Targeted Drug Therapies

artículo científico publicado en 2015

An Integrative Model of Cellular States, Plasticity, and Genetics for Glioblastoma

scientific article published on 18 July 2019

BAF Complex Maintains Glioma Stem Cells in Pediatric H3K27M Glioma

scientific article published in 2022

Clinical targeted exome-based sequencing in combination with genome-wide copy number profiling: precision medicine analysis of 203 pediatric brain tumors.

artículo científico publicado en 2017

DIPG-06. REDEFINING THE CELLULAR ARCHITECTURE OF DIFFUSE MIDLINE GLIOMAS WITH H3 K27M MUTATIONS THROUGH LARGE-SCALE SINGLE-CELL ANALYSES.

artículo científico publicado en 2017

DIPG-29. GENOMIC LANDSCAPE OF DIFFUSE INTRINSIC PONTINE GLIOMA: AN ANALYSIS OF THE DIPG-BATS COHORT.

artículo científico publicado en 2017

DIPG-52. ACTIVE CHROMATIN IN H3K27M DIPG REVEALS DISTINCT EPIGENETIC SUBTYPES AND SUBTYPE-SPECIFIC MECHANISMS OF PATHOGENESIS

Decoupling genetics, lineages, and microenvironment in IDH-mutant gliomas by single-cell RNA-seq.

artículo científico publicado en 2017

Developmental and oncogenic programs in H3K27M gliomas dissected by single-cell RNA-seq

artículo científico publicado en 2018

Developmental origins and emerging therapeutic opportunities for childhood cancer

EPEN-13. OUTCOMES AFTER FIRST RELAPSE OF CHILDHOOD INTRACRANIAL EPENDYMOMA: A SINGLE INSTITUTION EXPERIENCE

EPT-20CLINICAL TARGETED EXOME-BASED SEQUENCING IN COMBINATION WITH GENOME WIDE COPY NUMBER PROFILING: A CLIA CERTIFIED APPROACH FOR PRECISION MEDICINE IN 203 PEDIATRIC BRAIN TUMOR PATIENTS.

artículo científico publicado en 2016

GENE-09. PRECISION MEDICINE ANALYSIS OF 203 PEDIATRIC BRAIN TUMORS REVEALS CLINICALLY RELEVANT GENOMIC ALTERATIONS.

artículo científico publicado en 2017

GENE-22. RE-PROGRAMING CHROMATIN WITH A BIFUNCTIONAL LSD1/HDAC INHIBITOR INDUCES THERAPEUTIC DIFFERENTIATION IN DIPG

Gliomas Genomics and Epigenomics: Arriving at the Start and Knowing It for the First Time

artículo científico publicado en 2016

Gliomas in Children.

artículo científico publicado en 2018

HG-110SINGLE-CELL TRANSCRIPTOME ANALYSIS IN PEDIATRIC HEMISPHERIC AND MIDLINE HIGH-GRADE GLIOMAS.

artículo científico publicado en 2016

HG-73SAFETY AND FEASIBILITY OF A MULTI-INSTITUTIONAL PHASE II TRIAL INCOPORATING BIOPSY AND MOLECULARLY DETERMINED TREATMENT OF CHILDREN AND YOUNG ADULTS WITH NEWLY DIAGNOSED DIFFUSE INTRINSIC PONTINE GLIOMAS (DIPG).

artículo científico publicado en 2016

Histone H3.3G34-Mutant Interneuron Progenitors Co-opt PDGFRA for Gliomagenesis

artículo científico publicado en 2020

Histone Variant and Cell Context Determine H3K27M Reprogramming of the Enhancer Landscape and Oncogenic State

scientific article published on 03 October 2019

How neuronal activity regulates glioma cell proliferation

artículo científico publicado en 2015

Increasing value of autopsies in patients with brain tumors in the molecular era

scientific article published on 30 September 2019

Infiltrative gliomas of the thalamus in children: the role of surgery in the era of H3 K27M mutant midline gliomas

artículo científico publicado en 2020

Into Thin Air: Hypoxia Drives Metabolic and Epigenomic Deregulation of Lethal Pediatric Ependymoma

artículo científico publicado en 2020

LGG-05. SINGLE CELL RNA SEQUENCING REVEALS MITOGENIC AND PROGENITOR GENE PROGRAMS IN BRAF-REARRANGED PILOCYTIC ASTROCYTOMAS

artículo científico publicado en 2019

LGG-12. TRAMETINIB FOR THE TREATMENT OF RECURRENT/PROGRESSIVE PEDIATRIC LOW GRADE GLIOMA: A SINGLE INSTITUTION EXPERIENCE

LGG-13. RESOLVING TRANSCRIPTIONAL PROFILES IN BRAF-REARRANGED PILOCYTIC ASTROCYTOMA USING SINGLE CELL RNA SEQUENCING

artículo científico publicado en 2018

MBRS-28. SINGLE-CELL TRANSCRIPTOME ANALYSIS OF MEDULLOBLASTOMA

Mitogenic and progenitor gene programmes in single pilocytic astrocytoma cells

artículo científico publicado en 2019

Molecular and clinicopathologic features of gliomas harboring NTRK fusions

artículo científico publicado en 2020

Molecular pathogenesis and therapeutic implications in pediatric high-grade gliomas

artículo científico publicado en 2017

Non-inflammatory tumor microenvironment of diffuse intrinsic pontine glioma.

artículo científico publicado en 2018

Of Brains and Blood: Developmental Origins of Glioma Diversity?

artículo científico publicado en 2015

PDCT-24. A PHASE I DOSE ESCALATION TRIAL OF THE MEK1/2 INHIBITOR MEK162 (BINIMETINIB) IN CHILDREN WITH LOW-GRADE GLIOMAS AND OTHER RAS-RAF PATHWAY-ACTIVATED TUMORS: INITIAL REPORT

PDTM-04. REDEFINING THE CELLULAR ARCHITECTURE OF DIFFUSE MIDLINE GLIOMAS WITH H3 K27M MUTATIONS THROUGH LARGE-SCALE SINGLE-CELL ANALYSES

PTPS-06SINGLE-CELL TRANSCRIPTOME ANALYSIS IN PEDIATRIC HIGH-GRADE GLIOMA.

artículo científico publicado en 2015

Rapid Generation of Somatic Mouse Mosaics with Locus-Specific, Stably Integrated Transgenic Elements

scientific article published on 01 September 2019

Re-programing Chromatin with a Bifunctional LSD1/HDAC Inhibitor Induces Therapeutic Differentiation in DIPG

scientific article published on 17 October 2019

Resolving medulloblastoma cellular architecture by single-cell genomics

artículo científico publicado en 2019

Single-Cell RNA-Seq Reveals Cellular Hierarchies and Impaired Developmental Trajectories in Pediatric Ependymoma

artículo científico publicado en 2020

Single-cell RNA-seq supports a developmental hierarchy in human oligodendroglioma

artículo científico publicado en 2016

Stalled developmental programs at the root of pediatric brain tumors

scientific article published on 25 November 2019

TMOD-01. CREDENTIALING NOVEL PEDIATRIC GLIOBLASTOMA AND EPENDYMOMA MODELS WITH SINGLE-CELL RNA SEQUENCING

artículo científico publicado en 2019

The growing role of epigenetics in childhood cancers

scientific article published on 01 February 2020

The landscape of tumor cell states and spatial organization in H3-K27M mutant diffuse midline glioma across age and location

scientific article published in 2022

Trametinib for the treatment of recurrent/progressive pediatric low-grade glioma

artículo científico publicado en 2020

Understanding The Epigenetic Landscape and Cellular Architecture of Childhood Brain Tumors

artículo científico publicado en 2020

Lista de obras de

A Brain Tumor/Organotypic Slice Co-culture System for Studying Tumor Microenvironment and Targeted Drug Therapies

An Integrative Model of Cellular States, Plasticity, and Genetics for Glioblastoma

BAF Complex Maintains Glioma Stem Cells in Pediatric H3K27M Glioma

Clinical targeted exome-based sequencing in combination with genome-wide copy number profiling: precision medicine analysis of 203 pediatric brain tumors.

DIPG-06. REDEFINING THE CELLULAR ARCHITECTURE OF DIFFUSE MIDLINE GLIOMAS WITH H3 K27M MUTATIONS THROUGH LARGE-SCALE SINGLE-CELL ANALYSES.

DIPG-29. GENOMIC LANDSCAPE OF DIFFUSE INTRINSIC PONTINE GLIOMA: AN ANALYSIS OF THE DIPG-BATS COHORT.

DIPG-52. ACTIVE CHROMATIN IN H3K27M DIPG REVEALS DISTINCT EPIGENETIC SUBTYPES AND SUBTYPE-SPECIFIC MECHANISMS OF PATHOGENESIS

Decoupling genetics, lineages, and microenvironment in IDH-mutant gliomas by single-cell RNA-seq.

Developmental and oncogenic programs in H3K27M gliomas dissected by single-cell RNA-seq

Developmental origins and emerging therapeutic opportunities for childhood cancer

EPEN-13. OUTCOMES AFTER FIRST RELAPSE OF CHILDHOOD INTRACRANIAL EPENDYMOMA: A SINGLE INSTITUTION EXPERIENCE

EPT-20CLINICAL TARGETED EXOME-BASED SEQUENCING IN COMBINATION WITH GENOME WIDE COPY NUMBER PROFILING: A CLIA CERTIFIED APPROACH FOR PRECISION MEDICINE IN 203 PEDIATRIC BRAIN TUMOR PATIENTS.

GENE-09. PRECISION MEDICINE ANALYSIS OF 203 PEDIATRIC BRAIN TUMORS REVEALS CLINICALLY RELEVANT GENOMIC ALTERATIONS.

GENE-22. RE-PROGRAMING CHROMATIN WITH A BIFUNCTIONAL LSD1/HDAC INHIBITOR INDUCES THERAPEUTIC DIFFERENTIATION IN DIPG

Gliomas Genomics and Epigenomics: Arriving at the Start and Knowing It for the First Time

Gliomas in Children.

HG-110SINGLE-CELL TRANSCRIPTOME ANALYSIS IN PEDIATRIC HEMISPHERIC AND MIDLINE HIGH-GRADE GLIOMAS.

HG-73SAFETY AND FEASIBILITY OF A MULTI-INSTITUTIONAL PHASE II TRIAL INCOPORATING BIOPSY AND MOLECULARLY DETERMINED TREATMENT OF CHILDREN AND YOUNG ADULTS WITH NEWLY DIAGNOSED DIFFUSE INTRINSIC PONTINE GLIOMAS (DIPG).

Histone H3.3G34-Mutant Interneuron Progenitors Co-opt PDGFRA for Gliomagenesis

Histone Variant and Cell Context Determine H3K27M Reprogramming of the Enhancer Landscape and Oncogenic State

How neuronal activity regulates glioma cell proliferation

Increasing value of autopsies in patients with brain tumors in the molecular era

Infiltrative gliomas of the thalamus in children: the role of surgery in the era of H3 K27M mutant midline gliomas

Into Thin Air: Hypoxia Drives Metabolic and Epigenomic Deregulation of Lethal Pediatric Ependymoma

LGG-05. SINGLE CELL RNA SEQUENCING REVEALS MITOGENIC AND PROGENITOR GENE PROGRAMS IN BRAF-REARRANGED PILOCYTIC ASTROCYTOMAS

LGG-12. TRAMETINIB FOR THE TREATMENT OF RECURRENT/PROGRESSIVE PEDIATRIC LOW GRADE GLIOMA: A SINGLE INSTITUTION EXPERIENCE

LGG-13. RESOLVING TRANSCRIPTIONAL PROFILES IN BRAF-REARRANGED PILOCYTIC ASTROCYTOMA USING SINGLE CELL RNA SEQUENCING

MBRS-28. SINGLE-CELL TRANSCRIPTOME ANALYSIS OF MEDULLOBLASTOMA

Mitogenic and progenitor gene programmes in single pilocytic astrocytoma cells

Molecular and clinicopathologic features of gliomas harboring NTRK fusions

Molecular pathogenesis and therapeutic implications in pediatric high-grade gliomas

Non-inflammatory tumor microenvironment of diffuse intrinsic pontine glioma.

Of Brains and Blood: Developmental Origins of Glioma Diversity?

PDCT-24. A PHASE I DOSE ESCALATION TRIAL OF THE MEK1/2 INHIBITOR MEK162 (BINIMETINIB) IN CHILDREN WITH LOW-GRADE GLIOMAS AND OTHER RAS-RAF PATHWAY-ACTIVATED TUMORS: INITIAL REPORT

PDTM-04. REDEFINING THE CELLULAR ARCHITECTURE OF DIFFUSE MIDLINE GLIOMAS WITH H3 K27M MUTATIONS THROUGH LARGE-SCALE SINGLE-CELL ANALYSES

PTPS-06SINGLE-CELL TRANSCRIPTOME ANALYSIS IN PEDIATRIC HIGH-GRADE GLIOMA.

Rapid Generation of Somatic Mouse Mosaics with Locus-Specific, Stably Integrated Transgenic Elements

Re-programing Chromatin with a Bifunctional LSD1/HDAC Inhibitor Induces Therapeutic Differentiation in DIPG

Resolving medulloblastoma cellular architecture by single-cell genomics

Single-Cell RNA-Seq Reveals Cellular Hierarchies and Impaired Developmental Trajectories in Pediatric Ependymoma

Single-cell RNA-seq supports a developmental hierarchy in human oligodendroglioma

Stalled developmental programs at the root of pediatric brain tumors

TMOD-01. CREDENTIALING NOVEL PEDIATRIC GLIOBLASTOMA AND EPENDYMOMA MODELS WITH SINGLE-CELL RNA SEQUENCING

The growing role of epigenetics in childhood cancers

The landscape of tumor cell states and spatial organization in H3-K27M mutant diffuse midline glioma across age and location

Trametinib for the treatment of recurrent/progressive pediatric low-grade glioma

Understanding The Epigenetic Landscape and Cellular Architecture of Childhood Brain Tumors