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A Novel Role for Bcl-2 in Regulation of Cellular Calcium Extrusion

artículo científico publicado el 14 de junio de 2012

A new technique for assessing the microscopic distribution of cellular calcium exit sites.

artículo científico publicado en 1996

ATP depletion induces translocation of STIM1 to puncta and formation of STIM1-ORAI1 clusters: translocation and re-translocation of STIM1 does not require ATP.

artículo científico publicado en 2008

ATP depletion inhibits Ca2+ release, influx and extrusion in pancreatic acinar cells but not pathological Ca2+ responses induced by bile

artículo científico publicado en 2007

Aberrant Ca2+ signalling through acidic calcium stores in pancreatic acinar cells

artículo científico publicado el 23 de marzo de 2011

Acetylcholine-evoked increase in the cytoplasmic Ca2+ concentration and Ca2+ extrusion measured simultaneously in single mouse pancreatic acinar cells

artículo científico publicado en 1992

Active mitochondria surrounding the pancreatic acinar granule region prevent spreading of inositol trisphosphate-evoked local cytosolic Ca(2+) signals.

artículo científico publicado en 1999

Bile acids induce calcium signals in mouse pancreatic acinar cells: implications for bile-induced pancreatic pathology.

artículo científico publicado en 2002

Biology, role and therapeutic potential of circulating histones in acute inflammatory disorders

scholarly article by Peter Szatmary et al published 1 October 2018 in Journal of Cellular and Molecular Medicine

Ca2+ flow via tunnels in polarized cells: recharging of apical Ca2+ stores by focal Ca2+ entry through basal membrane patch.

artículo científico publicado en 1997

Caffeine protects against experimental acute pancreatitis by inhibition of inositol 1,4,5-trisphosphate receptor-mediated Ca2+ release

artículo científico publicado en 2015

Calcium binding capacity of the cytosol and endoplasmic reticulum of mouse pancreatic acinar cells.

artículo científico publicado en 1999

Calcium clamp in single nerve cells.

artículo científico publicado en 1993

Calcium dependence of calcium extrusion and calcium uptake in mouse pancreatic acinar cells

artículo científico publicado en 1996

Calcium elevation in mitochondria is the main Ca2+ requirement for mitochondrial permeability transition pore (mPTP) opening.

artículo científico publicado en 2009

Calcium gradients and the Golgi.

artículo científico publicado en 2006

Calcium transport pathways in the nucleus.

artículo científico publicado en 1996

Calcium uptake via endocytosis with rapid release from acidifying endosomes.

artículo científico publicado en 1998

Calcium-dependent release of NO from intracellular S-nitrosothiols

artículo científico publicado en 2006

Calmodulin protects against alcohol-induced pancreatic trypsinogen activation elicited via Ca2+ release through IP3 receptors

scientific journal article

Caspase-8-mediated apoptosis induced by oxidative stress is independent of the intrinsic pathway and dependent on cathepsins

artículo científico publicado en 2007

Cellular geography of IP3 receptors, STIM and Orai: a lesson from secretory epithelial cells.

artículo científico

Correlation of NADH and Ca2+ signals in mouse pancreatic acinar cells.

artículo científico publicado en 2002

Decoding glutamate receptor activation by the Ca2+ sensor protein hippocalcin in rat hippocampal neurons

scientific journal article

Decrease of acidity inside zymogen granules inhibits acetylcholine- or inositol trisphosphate-evoked cytosolic Ca2+ spiking in pancreatic acinar cells

artículo científico publicado en 1996

Differential use of myristoyl groups on neuronal calcium sensor proteins as a determinant of spatio-temporal aspects of Ca2+ signal transduction

artículo científico publicado en 2002

Direct activation of cytosolic Ca2+ signaling and enzyme secretion by cholecystokinin in human pancreatic acinar cells.

artículo científico publicado en 2008

Dual sensitivity of sarcoplasmic/endoplasmic Ca2+-ATPase to cytosolic and endoplasmic reticulum Ca2+ as a mechanism of modulating cytosolic Ca2+ oscillations.

artículo científico publicado en 2004

Dynamic changes in cytosolic and mitochondrial ATP levels in pancreatic acinar cells

artículo científico publicado en 2010

Dynamics and calcium sensitivity of the Ca2+/myristoyl switch protein hippocalcin in living cells

artículo científico publicado en 2003

Effect of Ag+ on membrane permeability of perfused Helix pomatia neurons

scientific article published on 01 October 1991

Effect of reduced extracellular level of sodium ions on the intracellular level of calcium ions in the cytoplasm of cultured rat cardiomyocytes

scientific article published on 01 November 1989

Effects of the mitochondria-targeted antioxidant mitoquinone in murine acute pancreatitis

artículo científico publicado en 2015

Endoplasmic reticulum-plasma membrane junctions: structure, function and dynamics.

artículo científico publicado en 2016

Epithelial-mesenchymal transition, IP3 receptors and ER-PM junctions: translocation of Ca2+ signalling complexes and regulation of migration

artículo científico publicado en 2016

Ethanol toxicity in pancreatic acinar cells: mediation by nonoxidative fatty acid metabolites

artículo científico publicado en 2004

Extrusion of calcium from a single isolated neuron of the snail Helix pomatia

artículo científico publicado en 1991

FF-ATP Synthase Inhibitory Factor 1 in the Normal Pancreas and in Pancreatic Ductal Adenocarcinoma: Effects on Bioenergetics, Invasion and Proliferation

scientific article published on 11 July 2018

Fatty acid ethyl ester synthase inhibition ameliorates ethanol-induced Ca2+-dependent mitochondrial dysfunction and acute pancreatitis

artículo científico publicado en 2013

Free calcium transients and oscillations in nerve cells

artículo científico publicado el 1 de enero de 1991

Free radicals and the pancreatic acinar cells: role in physiology and pathology

artículo científico publicado en 2005

Generation and modulation of cytosolic Ca2+ signals in pancreatic acinar cells: techniques and mechanisms

artículo científico publicado el 1 de octubre de 2003

Hippocalcin signaling via site-specific translocation in hippocampal neurons

artículo científico publicado en 2008

Hormone-induced secretory and nuclear translocation of calmodulin: oscillations of calmodulin concentration with the nucleus as an integrator

artículo científico publicado en 1999

How to measure Ca2+ in cellular organelles?

artículo científico publicado en 2005

How to win ATP and influence Ca(2+) signaling.

artículo científico

Inhibitors of ORAI1 Prevent Cytosolic Calcium-Associated Injury of Human Pancreatic Acinar Cells and Acute Pancreatitis in 3 Mouse Models

artículo científico publicado en 2015

Inositol-1,4,5-trisphosphate and non-hydrolysable GTP analogue induced calcium release from intracellular stores of the Helix pomatia neurons

artículo científico publicado en 1990

InsP₃receptors and Orai channels in pancreatic acinar cells: co-localization and its consequences

scientific journal article

Intracellular glucose switches between cyclic ADP-ribose and inositol trisphosphate triggering of cytosolic Ca2+ spiking

artículo científico publicado en 1998

Intracellular rupture, exocytosis and actin interaction of endocytic vacuoles in pancreatic acinar cells: initiating events in acute pancreatitis.

artículo científico publicado en 2018

Intramitochondrial Ca(2+) Sensing by EMRE: The Matrix Outlook on Stimulus-Metabolism Coupling.

artículo científico publicado en 2016

Introduction

Isoproterenol evokes extracellular Ca2+ spikes due to secretory events in salivary gland cells

scientific article published on 01 February 1998

LAP-like non-canonical autophagy and evolution of endocytic vacuoles in pancreatic acinar cells

artículo científico publicado en 2019

Levels of the Autophagy Related 5 Protein Affect Progression and Metastasis of Pancreatic Tumors in Mice

artículo científico publicado en 2018

Local uncaging of caged Ca(2+) reveals distribution of Ca(2+)-activated Cl(-) channels in pancreatic acinar cells.

artículo científico publicado en 2001

Localization of Ca2+ extrusion sites in pancreatic acinar cells

scientific article published on 01 March 1996

Mechanism of mitochondrial permeability transition pore induction and damage in the pancreas: inhibition prevents acute pancreatitis by protecting production of ATP.

artículo científico publicado en 2015

Mechanisms of cellular calcium oscillations in secretory cells

artículo científico publicado el 27 de octubre de 1992

Menadione-induced reactive oxygen species generation via redox cycling promotes apoptosis of murine pancreatic acinar cells.

artículo científico publicado en 2006

Mitochondrial Targeting of Antioxidants Alters Pancreatic Acinar Cell Bioenergetics and Determines Cell Fate

artículo científico publicado en 2019

Mitochondrial calcium in the life and death of exocrine secretory cells.

artículo científico

Mitochondrial junctions with cellular organelles: Ca2+ signalling perspective

artículo científico publicado en 2018

Mitochondrial signalling, physiology and pathophysiology

artículo científico publicado en 2018

Modulation of calcium signalling by mitochondria.

artículo científico publicado en 2009

Movement of calcium signals and calcium-binding proteins: firewalls, traps and tunnels.

artículo científico publicado en 2006

NAADP mobilizes Ca2+ from a thapsigargin-sensitive store in the nuclear envelope by activating ryanodine receptors

artículo científico publicado el 20 de octubre de 2003

NAADP, cADPR and IP3 all release Ca2+ from the endoplasmic reticulum and an acidic store in the secretory granule area.

artículo científico publicado en 2006

New Aspects of the Contribution of ER to SOCE Regulation: The Role of the ER and ER-Plasma Membrane Junctions in the Regulation of SOCE.

artículo científico publicado en 2017

Non-uniform distribution of mitochondria in pancreatic acinar cells

scientific article published on 28 June 2003

Novel lipophilic probe for detecting near-membrane reactive oxygen species responses and its application for studies of pancreatic acinar cells: effects of pyocyanin and L-ornithine

artículo científico publicado en 2014

Oxidative stress alters mitochondrial bioenergetics and modifies pancreatic cell death independently of cyclophilin D, resulting in an apoptosis-to-necrosis shift.

artículo científico publicado en 2018

Pancreatic protease activation by alcohol metabolite depends on Ca2+ release via acid store IP3 receptors

artículo científico publicado en 2009

Perinuclear, perigranular and sub-plasmalemmal mitochondria have distinct functions in the regulation of cellular calcium transport.

artículo científico publicado en 2001

Pharmacologically directed cell disposal: labeling damaged cells for phagocytosis as a strategy against acute pancreatitis

artículo científico publicado en 2010

Pulsatile Ca2+ extrusion from single pancreatic acinar cells during receptor-activated cytosolic Ca2+ spiking

artículo científico publicado en 1992

Reactive oxygen species induced by bile acid induce apoptosis and protect against necrosis in pancreatic acinar cells

artículo científico publicado en 2011

Regulation of early response genes in pancreatic acinar cells: external calcium and nuclear calcium signalling aspects.

artículo científico publicado en 2008

Ribosome-free terminals of rough ER allow formation of STIM1 puncta and segregation of STIM1 from IP(3) receptors.

artículo científico publicado en 2009

Role of phosphoinositides in STIM1 dynamics and store-operated calcium entry

artículo científico publicado en 2009

Saltatory formation, sliding and dissolution of ER-PM junctions in migrating cancer cells.

artículo científico publicado en 2013

Selective inhibition of BET proteins reduces pancreatic damage and systemic inflammation in bile acid- and fatty acid ethyl ester- but not caerulein-induced acute pancreatitis.

artículo científico publicado en 2017

Signal transduction, calcium and acute pancreatitis.

artículo científico publicado en 2003

Stable Golgi-mitochondria complexes and formation of Golgi Ca(2+) gradients in pancreatic acinar cells.

artículo científico publicado en 2005

Systemic histone release disrupts plasmalemma and contributes to necrosis in acute pancreatitis.

artículo científico publicado en 2017

TRO40303 Ameliorates Alcohol-Induced Pancreatitis Through Reduction of Fatty Acid Ethyl Ester-Induced Mitochondrial Injury and Necrotic Cell Death

artículo científico publicado en 2017

Termination of cytosolic Ca2+ signals: Ca2+ reuptake into intracellular stores is regulated by the free Ca2+ concentration in the store lumen

artículo científico publicado el 15 de enero de 1998

The calcium store in the nuclear envelope

scientific article published on 01 February 1998

The distribution of the endoplasmic reticulum in living pancreatic acinar cells.

artículo científico publicado en 2002

The droplet technique: measurement of calcium extrusion from single isolated mammalian cells

scientific article published on 01 October 1994

The relationship between acetylcholine-evoked Ca(2+)-dependent current and the Ca2+ concentrations in the cytosol and the lumen of the endoplasmic reticulum in pancreatic acinar cells

scientific article published on 01 November 1999

The role of Ca2+ influx in endocytic vacuole formation in pancreatic acinar cells

artículo científico publicado en 2015

Traffic of Kv4 K+ channels mediated by KChIP1 is via a novel post-ER vesicular pathway

artículo científico publicado en 2005

Transformation of local Ca2+ spikes to global Ca2+ transients: the combinatorial roles of multiple Ca2+ releasing messengers

artículo científico publicado en 2002

Use of a microfluorometric method for measuring free calcium in the cytoplasm of isolated cultured rat cardiomyocytes

artículo científico publicado en 1989

What can we learn about cell signalling by combining optical imaging and patch clamp techniques?

artículo científico publicado en 2002

[2 calcium currents in the somatic membrane of neurons of Helix pomatia]

scientific article published on 01 January 1985

[Calcium release from the intracellular stores of the soma of the mollusk neuron under the action of inositol triphosphate and its nonhydrolyzable analog GTP]

artículo científico publicado en 1989

[Changes in the intracellular concentration of calcium ions in isolated neurons of the edible snail detected by chlortetracycline fluorescence]

scientific article published on 01 January 1987

[Relation between the surface potential of mouse neuroblastoma clone C1300 cells and the phase of the cell cycle]

artículo científico publicado en 1987

cAMP induces stromal interaction molecule 1 (STIM1) puncta but neither Orai1 protein clustering nor store-operated Ca2+ entry (SOCE) in islet cells

artículo científico publicado en 2012

cAMP inhibits migration, ruffling and paxillin accumulation in focal adhesions of pancreatic ductal adenocarcinoma cells: effects of PKA and EPAC.

artículo científico publicado en 2013