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A critical residue selectively recruits nucleotides for t7 RNA polymerase transcription fidelity control.

artículo científico publicado en 2014

Application of Markov State Models to simulate long timescale dynamics of biological macromolecules.

artículo científico publicado en 2014

Characterization and Nonenzymatic Transformation of Three Types of Alkaloids from Streptomyces albogriseolus MGR072 and Discovery of Inhibitors of Indoleamine 2,3-Dioxygenase

scientific article published on 15 October 2019

Dynamics of pyrophosphate ion release and its coupled trigger loop motion from closed to open state in RNA polymerase II.

artículo científico publicado en 2012

Millisecond dynamics of RNA polymerase II translocation at atomic resolution

artículo científico publicado en 2014

Molecular basis of transcriptional fidelity and DNA lesion-induced transcriptional mutagenesis

artículo científico publicado en 2014

Monitoring and Inhibition of Insulin Fibrillation by a Small Organic Fluorogen with Aggregation-Induced Emission Characteristics

article

Refolding Dynamics of gp41 from Pre-fusion to Pre-hairpin States during HIV-1 Entry

scientific article published on 31 December 2019

T7 RNA polymerase translocation is facilitated by a helix opening on the fingers domain that may also prevent backtracking.

artículo científico publicado en 2017

Understanding of the bridging sheet formation of HIV-1 glycoprotein gp120

artículo científico publicado en 2009

Understanding the binding mode and function of BMS-488043 against HIV-1 viral entry

artículo científico publicado en 2011

pH-Induced Misfolding Mechanism of Prion Protein: Insights from Microsecond-Accelerated Molecular Dynamics Simulations

article