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A DNA methylation biomarker of alcohol consumption.

artículo científico publicado en 2016

A combined analysis of genetically correlated traits identifies 187 loci and a role for neurogenesis and myelination in intelligence.

artículo científico publicado en 2018

A meta-analysis of 120 246 individuals identifies 18 new loci for fibrinogen concentration

artículo científico publicado en 2015

A meta-analysis of genome-wide association studies of epigenetic age acceleration

artículo científico publicado en 2019

Active cognitive lifestyle associates with cognitive recovery and a reduced risk of cognitive decline

artículo científico publicado en 2012

Active cognitive lifestyle is associated with positive cognitive health transitions and compression of morbidity from age sixty-five

artículo científico publicado en 2012

Addendum: Genome-wide association study of depression phenotypes in UK Biobank identifies variants in excitatory synaptic pathways

artículo científico publicado en 2018

Age-associated cognitive decline

artículo científico publicado en 2009

Age-dependent DNA methylation patterns on the Y chromosome in elderly males

scientific article published on 21 February 2019

Age-related gene expression changes, and transcriptome wide association study of physical and cognitive aging traits, in the Lothian Birth Cohort 1936.

artículo científico publicado en 2017

Altered DNA methylation associated with a translocation linked to major mental illness.

artículo científico publicado en 2018

An epigenetic predictor of death captures multi-modal measures of brain health

scientific article published on 03 December 2019

An epigenetic score for BMI based on DNA methylation correlates with poor physical health and major disease in the Lothian Birth Cohort

article

An epigenome-wide association study meta-analysis of educational attainment.

artículo científico publicado en 2017

An epigenome-wide association study of sex-specific chronological ageing

artículo científico publicado en 2019

Assessing the genetic overlap between BMI and cognitive function

artículo científico publicado en 2016

Association analysis in over 329,000 individuals identifies 116 independent variants influencing neuroticism.

artículo científico publicado en 2017

Association between polymorphisms of the dopamine receptor D2 and catechol-o-methyl transferase genes and cognitive function

artículo científico publicado en 2010

Association between raised inflammatory markers and cognitive decline in elderly people with type 2 diabetes: the Edinburgh Type 2 Diabetes Study

artículo científico publicado en 2009

Association of Body Mass Index with DNA Methylation and Gene Expression in Blood Cells and Relations to Cardiometabolic Disease: A Mendelian Randomization Approach

artículo científico publicado en 2017

Association of KIBRA and memory

artículo científico publicado en 2009

Association of Methylation Signals With Incident Coronary Heart Disease in an Epigenome-Wide Assessment of Circulating Tumor Necrosis Factor α.

artículo científico publicado en 2018

Association of facial ageing with DNA methylation and epigenetic age predictions

artículo científico publicado en 2018

Association of low-frequency and rare coding-sequence variants with blood lipids and coronary heart disease in 56,000 whites and blacks

artículo científico publicado en 2014

Associations between polymorphisms in five inflammation-related genes and cognitive ability in older persons.

artículo científico publicado en 2010

Author Correction: Association analysis in over 329,000 individuals identifies 116 independent variants influencing neuroticism

scientific article published on 01 March 2019

Author Correction: Bayesian reassessment of the epigenetic architecture of complex traits

scientific article published on 09 October 2020

Author Correction: Misestimation of heritability and prediction accuracy of male-pattern baldness

scientific article published in Nature Communications

Author Correction: Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function

scientific article published on 01 May 2019

Bayesian reassessment of the epigenetic architecture of complex traits

artículo científico publicado en 2020

Birth weight associations with DNA methylation differences in an adult population

artículo científico publicado en 2020

Blood rheology and cognition in the Edinburgh Type 2 Diabetes Study

artículo científico publicado en 2010

Brain age and other bodily ‘ages’: implications for neuropsychiatry

artículo científico publicado en 2019

Brain age predicts mortality.

artículo científico publicado en 2017

C-reactive protein, APOE genotype and longitudinal cognitive change in an older population

artículo científico publicado en 2013

Characterisation of an inflammation-related epigenetic score and its association with cognitive ability

artículo científico publicado en 2020

Childhood intelligence attenuates the association between biological ageing and health outcomes in later life

scientific article published on 28 November 2019

Chronic kidney disease: a risk factor for dementia onset: a population-based study. The Osaki-Tajiri Project.

artículo científico publicado en 2011

Cognitive function, dementia and type 2 diabetes mellitus in the elderly

artículo científico publicado en 2011

Cognitive lifestyle jointly predicts longitudinal cognitive decline and mortality risk

artículo científico publicado en 2014

Common genetic variants associated with cognitive performance identified using the proxy-phenotype method

artículo científico publicado en 2014

Common genetic variants explain the majority of the correlation between height and intelligence: the generation Scotland study.

artículo científico publicado en 2014

Comparison of HapMap and 1000 Genomes Reference Panels in a Large-Scale Genome-Wide Association Study

artículo científico publicado en 2017

CovidLife: a resource to understand mental health, well-being and behaviour during the COVID-19 pandemic in the UK

artículo científico publicado en 2021

Current versus lifetime depression, APOE variation, and their interaction on cognitive performance in younger and older adults

artículo científico publicado en 2015

DNA Methylation Analysis Identifies Loci for Blood Pressure Regulation

artículo científico publicado en 2017

DNA Methylation Signatures of Depressive Symptoms in Middle-aged and Elderly Persons: Meta-analysis of Multiethnic Epigenome-wide Studies

article published in 2018

DNA Methylation and Protein Markers of Chronic Inflammation and Their Associations With Brain and Cognitive Aging

artículo científico publicado en 2021

DNA methylation age of blood predicts all-cause mortality in later life

artículo científico publicado en 2015

DNA methylation and the epigenetic clock in relation to physical frailty in older people: the Lothian Birth Cohort 1936

scholarly article by Catharine R Gale published in August 2018

DNA methylation signatures of chronic low-grade inflammation are associated with complex diseases

artículo científico publicado en 2016

DNA methylation-based measures of biological age: meta-analysis predicting time to death

artículo científico publicado en 2016

DNA methylome profiling of all-cause mortality in comparison with age-associated methylation patterns

artículo científico publicado en 2019

Differential effects of the APOE e4 allele on different domains of cognitive ability across the life-course

artículo científico publicado en 2015

Effect of Smoking on Blood Pressure and Resting Heart Rate: A Mendelian Randomization Meta-Analysis in the CARTA Consortium

artículo científico publicado en 2015

Epigenetic Patterns in Blood Associated With Lipid Traits Predict Incident Coronary Heart Disease Events and Are Enriched for Results From Genome-Wide Association Studies

artículo científico publicado en 2017

Epigenetic Signatures of Cigarette Smoking

artículo científico publicado en 2016

Epigenetic influences on aging: a longitudinal genome-wide methylation study in old Swedish twins

artículo científico publicado en 2018

Epigenetic measures of ageing predict the prevalence and incidence of leading causes of death and disease burden

artículo científico publicado en 2020

Epigenetic prediction of complex traits and death

article by Daniel L McCartney et al published 27 September 2018 in Genome Biology

Epigenetic prediction of major depressive disorder

artículo científico publicado en 2020

Epigenetic scores for the circulating proteome as tools for disease prediction

artículo científico publicado en 2022

Epigenetic signatures of smoking associate with cognitive function, brain structure, and mental and physical health outcomes in the Lothian Birth Cohort 1936

artículo científico publicado en 2019

Epigenetic signatures of starting and stopping smoking

artículo científico publicado en 2018

Examining the Impact of Imputation Errors on Fine-Mapping Using DNA Methylation QTL as a Model Trait

scientific article published on 30 April 2019

Examining the influence of gender, education, social class and birth cohort on MMSE tracking over time: a population-based prospective cohort study

artículo científico publicado en 2012

Exome sequencing to detect rare variants associated with general cognitive ability: a pilot study.

artículo científico

Exploratory analysis of age and sex dependent DNA methylation patterns on the X-chromosome in whole blood samples

artículo científico publicado en 2020

Feasibility and ethics of using data from the Scottish newborn blood spot archive for research

artículo científico publicado en 2022

GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes

artículo científico publicado en 2018

GWAS of epigenetic aging rates in blood reveals a critical role for TERT.

artículo científico publicado en 2018

GWAS on family history of Alzheimer's disease.

artículo científico publicado en 2018

Genetic Associations Between Fibrinogen and Cognitive Performance in Three Scottish Cohorts

article

Genetic Stratification to Identify Risk Groups for Alzheimer's Disease

artículo científico publicado en 2017

Genetic Variants Associated With Altered Plasma Levels of C-Reactive Protein are not Associated With Late-Life Cognitive Ability in Four Scottish Samples

article

Genetic and environmental exposures constrain epigenetic drift over the human life course

artículo científico publicado en 2014

Genetic contributions to variation in general cognitive function: a meta-analysis of genome-wide association studies in the CHARGE consortium (N=53949).

artículo científico publicado en 2015

Genetic prediction of male pattern baldness.

artículo científico publicado en 2017

Genetic variants linked to education predict longevity

artículo científico publicado en 2016

Genetically defined elevated homocysteine levels do not result in widespread changes of DNA methylation in leukocytes

artículo científico publicado en 2017

Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders

artículo científico publicado en 2018

Genome-wide analysis of over 106 000 individuals identifies 9 neuroticism-associated loci.

artículo científico publicado en 2016

Genome-wide analysis of over 106 000 individuals identifies 9 neuroticism-associated loci.

artículo científico publicado en 2016

Genome-wide association studies identify 137 genetic loci for DNA methylation biomarkers of aging

artículo científico publicado en 2021

Genome-wide association study identifies 74 loci associated with educational attainment

artículo científico publicado en 2016

Genome-wide association study of cognitive functions and educational attainment in UK Biobank (N=112 151).

artículo científico publicado en 2016

Genome-wide association study of depression phenotypes in UK Biobank (n = 322,580) identifies the enrichment of variants in excitatory synaptic pathways

Genome-wide association study of depression phenotypes in UK Biobank identifies variants in excitatory synaptic pathways.

artículo científico publicado en 2018

Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions

artículo científico publicado en 2019

Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions.: Supplementary Information

Genomic and phenotypic insights from an atlas of genetic effects on DNA methylation

artículo científico publicado en 2021

Genomic structural equation modelling provides insights into the multivariate genetic architecture of complex traits

artículo científico publicado en 2019

Genotype effects contribute to variation in longitudinal methylome patterns in older people

artículo científico publicado en 2018

Heavier smoking may lead to a relative increase in waist circumference: evidence for a causal relationship from a Mendelian randomisation meta-analysis. The CARTA consortium

artículo científico publicado en 2015

Human cognitive ability is influenced by genetic variation in components of postsynaptic signalling complexes assembled by NMDA receptors and MAGUK proteins.

artículo científico publicado en 2014

Identification of novel differentially methylated sites with potential as clinical predictors of impaired respiratory function and COPD

artículo científico publicado en 2019

Identification, replication and characterization of epigenetic remodelling in the aging genome: a cross population analysis

artículo científico publicado en 2017

Identifying gene targets for brain-related traits using transcriptomic and methylomic data from blood.

artículo científico publicado en 2018

Improved precision of epigenetic clock estimates across tissues and its implication for biological ageing

scientific article published on 23 August 2019

Improving Phenotypic Prediction by Combining Genetic and Epigenetic Associations

artículo científico publicado en 2015

Improving access to psychological therapies and older people: findings from the Eastern Region

artículo científico publicado en 2014

Integrative analysis of omics summary data reveals putative mechanisms underlying complex traits.

artículo científico publicado en 2018

Investigating the possible causal association of smoking with depression and anxiety using Mendelian randomisation meta-analysis: the CARTA consortium

artículo científico publicado en 2014

Investigating the relationship between DNA methylation age acceleration and risk factors for Alzheimer's disease

artículo científico publicado en 2018

Longitudinal telomere length shortening and cognitive and physical decline in later life: The Lothian Birth Cohorts 1936 and 1921.

artículo científico publicado en 2016

Markers of Psychological Differences and Social and Health Inequalities: Possible Genetic and Phenotypic Overlaps

artículo científico publicado en 2015

Meta-analysis of epigenome-wide association studies of cognitive abilities

artículo científico publicado en 2018

Meta-analysis of up to 622,409 individuals identifies 40 novel smoking behaviour associated genetic loci

artículo científico publicado en 2019

Misestimation of heritability and prediction accuracy of male-pattern baldness.

artículo científico publicado en 2018

Molecular Genetic Contributions to Social Deprivation and Household Income in UK Biobank.

artículo científico publicado en 2016

Molecular genetic contributions to self-rated health.

artículo científico publicado en 2016

Molecular genetic contributions to socioeconomic status and intelligence.

artículo científico publicado en 2014

Multi-method genome- and epigenome-wide studies of inflammatory protein levels in healthy older adults

artículo científico publicado en 2020

Multiethnic Exome-Wide Association Study of Subclinical Atherosclerosis.

artículo científico publicado en 2016

Neurology-related protein biomarkers are associated with cognitive ability and brain volume in older age

scientific article published on 10 February 2020

New Blood Pressure-Associated Loci Identified in Meta-Analyses of 475 000 Individuals

artículo científico publicado en 2017

Ninety-nine independent genetic loci influencing general cognitive function include genes associated with brain health and structure (N = 280,360)

No association between Cholinergic Muscarinic Receptor 2 (CHRM2) genetic variation and cognitive abilities in three independent samples

artículo científico publicado en 2009

Parent of origin genetic effects on methylation in humans are common and influence complex trait variation

artículo científico publicado en 2019

Partial reprogramming induces a steady decline in epigenetic age before loss of somatic identity

artículo científico publicado en 2018

Peripheral levels of fibrinogen, C-reactive protein, and plasma viscosity predict future cognitive decline in individuals without dementia

artículo científico publicado en 2009

Phenotypic and genetic analysis of cognitive performance in Major Depressive Disorder in the Generation Scotland: Scottish Family Health Study

artículo científico publicado en 2018

Polygenic risk of ischemic stroke is associated with cognitive ability

artículo científico publicado en 2015

Publisher Correction: Parent of origin genetic effects on methylation in humans are common and influence complex trait variation

artículo científico publicado en 2019

Rare and low-frequency variants and their association with plasma levels of fibrinogen, FVII, FVIII, and vWF

artículo científico publicado en 2015

Reverse causation in the association between C-reactive protein and fibrinogen levels and cognitive abilities in an aging sample.

artículo científico publicado en 2009

Risk prediction of late-onset Alzheimer's disease implies an oligogenic architecture

scientific article published on 23 September 2020

RuralCovidLife: A new resource for the impact of the pandemic on rural Scotland

artículo científico publicado en 2022

Serum angiotensin-converting enzyme and frequency of severe hypoglycaemia in Type 1 diabetes: does a relationship exist?

artículo científico publicado en 2007

Shared genetic aetiology between cognitive functions and physical and mental health in UK Biobank (N = 112 151) and 24 GWAS consortia

article

Shared genetic aetiology between cognitive functions and physical and mental health in UK Biobank (N=112 151) and 24 GWAS consortia

artículo científico publicado en 2016

Short telomere length is associated with impaired cognitive performance in European ancestry cohorts.

artículo científico publicado en 2017

Social activity, cognitive decline and dementia risk: a 20-year prospective cohort study

artículo científico publicado en 2015

Social adversity and epigenetic aging: a multi-cohort study on socioeconomic differences in peripheral blood DNA methylation

artículo científico publicado en 2017

Stratification by smoking status reveals an association of CHRNA5-A3-B4 genotype with body mass index in never smokers

artículo científico publicado en 2014

Structural Brain MRI Trait Polygenic Score Prediction of Cognitive Abilities

artículo científico publicado en 2015

Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function

artículo científico publicado en 2018

TeenCovidLife: a resource to understand the impact of the COVID-19 pandemic on adolescents in Scotland

artículo científico publicado en 2022

The association between late-life cognitive test scores and retrospective informant interview data

artículo científico publicado en 2010

The epigenetic clock and objectively measured sedentary and walking behavior in older adults: the Lothian Birth Cohort 1936.

artículo científico publicado en 2018

The epigenetic clock and telomere length are independently associated with chronological age and mortality

artículo científico publicado en 2016

The epigenetic clock and telomere length are independently associated with chronological age and mortality

artículo científico publicado en 2017

The epigenetic clock is correlated with physical and cognitive fitness in the Lothian Birth Cohort 1936

artículo científico publicado en 2015

The reliability of assigning individuals to cognitive states using the Mini Mental-State Examination: a population-based prospective cohort study

artículo científico publicado en 2011

The total burden of rare, non-synonymous exome genetic variants is not associated with childhood or late-life cognitive ability

article by Riccardo E Marioni et al published 22 April 2014 in Proceedings of the Royal Society B

Tracking the Epigenetic Clock Across the Human Life Course: A Meta-analysis of Longitudinal Cohort Data

artículo científico publicado en 2019

Trajectories of inflammatory biomarkers over the eighth decade and their associations with immune cell profiles and epigenetic ageing

article by Anna J Stevenson et al published 20 December 2018 in Clinical epigenetics

Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension

artículo científico publicado en 2016

Using tree-based methods for detection of gene–gene interactions in the presence of a polygenic signal: simulation study with application to educational attainment in the Generation Scotland Cohort Study

article

Variation in the uric acid transporter gene (SLC2A9) and memory performance

artículo científico publicado en 2010

Weighted gene co-regulation network analysis (WGCNA) of promoter DNA methylation on all-cause mortality in old-aged birth cohorts finds modules of high-risk associated biomarkers

artículo científico publicado en 2020