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Lista de obras de Adrie Jc Steyn

2-Mercapto-Quinazolinones as Inhibitors of Type II NADH Dehydrogenase and Mycobacterium tuberculosis: Structure-Activity Relationships, Mechanism of Action and Absorption, Distribution, Metabolism, and Excretion Characterization.

artículo científico publicado en 2018

<i>Mycobacterium tuberculosis</i> causes a leaky blood‐brain barrier and neuroinflammation in the prefrontal cortex and cerebellum regions of infected mice offspring

artículo científico publicado en 2021

A Feedback Regulatory Loop Containing McdR and WhiB2 Controls Cell Division and DNA Repair in Mycobacteria

artículo científico publicado en 2022

A Rapid Drug Resistance Genotyping Workflow for Mycobacterium tuberculosis, Using Targeted Isothermal Amplification and Nanopore Sequencing

artículo científico publicado en 2021

A high‐resolution 3D atlas of the spectrum of tuberculous and COVID ‐19 lung lesions

artículo científico publicado en 2022

A partner for the resuscitation-promoting factors of Mycobacterium tuberculosis

scientific journal article

A screen to identify small molecule inhibitors of protein-protein interactions in mycobacteria

artículo científico publicado en 2011

Accessible and distinct decoquinate derivatives active against Mycobacterium tuberculosis and apicomplexan parasites

scholarly article

Aggregated <i>Mycobacterium tuberculosis</i> Enhances the Inflammatory Response

artículo científico publicado en 2021

Arylvinylpiperazine Amides, a New Class of Potent Inhibitors Targeting QcrB of Mycobacterium tuberculosis

artículo científico publicado en 2018

Attenuated heme oxygenase-1 responses predispose the elderly to pulmonary nontuberculous mycobacterial infections.

artículo científico publicado en 2016

B cell heterogeneity in human tuberculosis highlights compartment-specific phenotype and functional roles

artículo científico publicado en 2024

Bedaquiline reprograms central metabolism to reveal glycolytic vulnerability in Mycobacterium tuberculosis

artículo científico publicado en 2020

Characterization of a novel alpha-amylase from Lipomyces kononenkoae and expression of its gene (LKA1) in Saccharomyces cerevisiae

artículo científico publicado en 1995

Characterization of the Mycobacterium tuberculosis iniBAC promoter, a promoter that responds to cell wall biosynthesis inhibition.

artículo científico publicado en 2000

Cloning and characterization of a second alpha-amylase gene (LKA2) from Lipomyces kononenkoae IGC4052B and its expression in Saccharomyces cerevisiae.

artículo científico publicado en 2003

Comprehensive examination of the mouse lung metabolome following Mycobacterium tuberculosis infection using a multiplatform mass spectrometry approach

scientific article published on 14 April 2020

Compromised Metabolic Reprogramming Is an Early Indicator of CD8+ T Cell Dysfunction during Chronic Mycobacterium tuberculosis Infection

scientific article published on 01 December 2019

Conservation of structure and protein-protein interactions mediated by the secreted mycobacterial proteins EsxA, EsxB, and EspA

scientific journal article

Correction: Mycobacterium tuberculosis arrests host cycle at the G1/S transition to establish long term infection.

artículo científico publicado en 2017

Differential skewing of donor-unrestricted and γδ T cell repertoires in tuberculosis-infected human lungs

artículo científico publicado en 2020

Dissecting virulence pathways of Mycobacterium tuberculosis through protein-protein association.

artículo científico publicado en 2006

Dual inhibition of the terminal oxidases eradicates antibiotic-tolerant Mycobacterium tuberculosis

artículo científico publicado en 2020

Environmental heme-based sensor proteins: implications for understanding bacterial pathogenesis.

artículo científico publicado en 2012

Ergothioneine Maintains Redox and Bioenergetic Homeostasis Essential for Drug Susceptibility and Virulence of Mycobacterium tuberculosis

artículo científico publicado en 2016

Exposure to cigarette smoke impacts myeloid-derived regulatory cell function and exacerbates airway hyper-responsiveness

artículo científico publicado en 2014

Expression and secretion of Bacillus amyloliquefaciens alpha-amylase by using the yeast pheromone alpha-factor promoter and leader sequence in Saccharomyces cerevisiae.

artículo científico publicado en 1993

Ferritin H Deficiency in Myeloid Compartments Dysregulates Host Energy Metabolism and Increases Susceptibility to Mycobacterium tuberculosis Infection.

artículo científico publicado en 2018

Formation of Lung Inducible Bronchus Associated Lymphoid Tissue Is Regulated by Mycobacterium tuberculosis Expressed Determinants

artículo científico publicado en 2020

Group 3 innate lymphoid cells mediate early protective immunity against tuberculosis

artículo científico publicado en 2019

HIV status alters disease severity and immune cell responses in Beta variant SARS-CoV-2 infection wave

artículo científico publicado en 2021

Heme oxygenase-1 promotes granuloma development and protects against dissemination of mycobacteria

artículo científico publicado en 2012

Heme oxygenase-1-derived carbon monoxide induces the Mycobacterium tuberculosis dormancy regulon

artículo científico publicado en 2008

Host Bioenergetic Parameters Reveal Cytotoxicity of Antituberculosis Drugs Undetected Using Conventional Viability Assays

artículo científico publicado en 2021

Host immunity increases Mycobacterium tuberculosis reliance on cytochrome bd oxidase

Host-pathogen redox dynamics modulate Mycobacterium tuberculosis pathogenesis.

artículo científico publicado en 2018

Human alveolar lining fluid from the elderly promotes Mycobacterium tuberculosis intracellular growth and translocation into the cytosol of alveolar epithelial cells

artículo científico publicado en 2024

Hydrogen sulfide dysregulates the immune response by suppressing central carbon metabolism to promote tuberculosis

scientific article published on 05 March 2020

Hydrogen sulfide stimulates Mycobacterium tuberculosis respiration, growth and pathogenesis

scientific article published on 28 January 2020

Integrating environmental health and genomics research in Africa: challenges and opportunities identified during a Human Heredity and Health in Africa (H3Africa) Consortium workshop

scientific article published on 27 August 2019

Interaction of the sensor module of Mycobacterium tuberculosis H37Rv KdpD with members of the Lpr family

scientific journal article

Iron sulfur cluster proteins and microbial regulation: implications for understanding tuberculosis

scientific article published on 04 April 2012

Metabolic plasticity of central carbon metabolism protects mycobacteria.

artículo científico publicado en 2015

Microanatomic Distribution of Myeloid Heme Oxygenase-1 Protects against Free Radical-Mediated Immunopathology in Human Tuberculosis

article

Microanatomic Distribution of Myeloid Heme Oxygenase-1 Protects against Free Radical-Mediated Immunopathology in Human Tuberculosis

artículo científico publicado en 2019

Micro–Computed Tomography Analysis of the Human Tuberculous Lung Reveals Remarkable Heterogeneity in Three-dimensional Granuloma Morphology

artículo científico publicado en 2021

Mycobacterial WhiB6 Differentially Regulates ESX-1 and the Dos Regulon to Modulate Granuloma Formation and Virulence in Zebrafish.

artículo científico publicado en 2016

Mycobacterium tuberculosis DosS binds H2S through its Fe3+ heme iron to regulate the DosR dormancy regulon

artículo científico publicado en 2022

Mycobacterium tuberculosis DosS is a redox sensor and DosT is a hypoxia sensor

scientific journal article

Mycobacterium tuberculosis H2S Functions as a Sink to Modulate Central Metabolism, Bioenergetics, and Drug Susceptibility

artículo científico publicado en 2021

Mycobacterium tuberculosis WhiB3 interacts with RpoV to affect host survival but is dispensable for in vivo growth.

artículo científico publicado en 2002

Mycobacterium tuberculosis WhiB3 maintains redox homeostasis by regulating virulence lipid anabolism to modulate macrophage response

scientific journal article

Mycobacterium tuberculosis WhiB3 responds to O2 and nitric oxide via its [4Fe-4S] cluster and is essential for nutrient starvation survival

scientific journal article

Mycobacterium tuberculosis WhiB3: a novel iron-sulfur cluster protein that regulates redox homeostasis and virulence.

artículo científico publicado en 2012

Mycobacterium tuberculosis WhiB4 regulates oxidative stress response to modulate survival and dissemination in vivo.

artículo científico publicado en 2012

Mycobacterium tuberculosis arrests host cycle at the G1/S transition to establish long term infection

artículo científico publicado en 2017

Mycobacterium tuberculosis-Induced Maternal Immune Activation Promotes Autism-Like Phenotype in Infected Mice Offspring

artículo científico publicado en 2021

NAD(H) homeostasis underlies host protection mediated by glycolytic myeloid cells in tuberculosis

artículo científico publicado en 2023

New 2-Ethylthio-4-methylaminoquinazoline derivatives inhibiting two subunits of cytochrome bc1 in Mycobacterium tuberculosis

scientific article published on 23 January 2020

Publisher Correction: Group 3 innate lymphoid cells mediate early protective immunity against tuberculosis

artículo científico publicado en 2019

Quantitative measurement of antibiotic resistance in Mycobacterium tuberculosis reveals genetic determinants of resistance and susceptibility in a target gene approach

artículo científico publicado en 2024

RbpA and σB association regulates polyphosphate levels to modulate mycobacterial isoniazid-tolerance

artículo científico publicado en 2018

Recent developments in mycobacterial research.

artículo científico publicado en 1999

Redox homeostasis in mycobacteria: the key to tuberculosis control?

artículo científico publicado en 2011

Reductive stress in microbes: implications for understanding Mycobacterium tuberculosis disease and persistence.

artículo científico publicado en 2010

Regional sequence homologies in starch-degrading enzymes.

artículo científico publicado en 1993

Regulation of Ergothioneine Biosynthesis and Its Effect on Mycobacterium tuberculosis Growth and Infectivity

artículo científico publicado en 2015

Relevance of the Warburg Effect in Tuberculosis for Host-Directed Therapy

artículo científico publicado en 2020

Remembering the Host in Tuberculosis Drug Development

scientific article published on 01 April 2019

Role of Ergothioneine in Microbial Physiology and Pathogenesis.

artículo científico publicado en 2017

S100A8/A9 proteins mediate neutrophilic inflammation and lung pathology during tuberculosis

artículo científico publicado en 2013

Susceptibility of Mycobacterium tuberculosis cytochrome bd oxidase mutants to compounds targeting the terminal respiratory oxidase, cytochrome c.

artículo científico publicado en 2017

The 2021 WHO catalogue of Mycobacterium tuberculosis complex mutations associated with drug resistance: a genotypic analysis

artículo científico publicado en 2022

The Analysis of Mycobacterium tuberculosis-Induced Bioenergetic Changes in Infected Macrophages Using an Extracellular Flux Analyzer

artículo científico publicado en 2020

The Physiology and Genetics of Oxidative Stress in Mycobacteria.

artículo científico

The Role of Host-Generated H<sub>2</sub>S in Microbial Pathogenesis: New Perspectives on Tuberculosis

artículo científico publicado en 2020

The emerging role of gasotransmitters in the pathogenesis of tuberculosis

artículo científico publicado en 2016

The immunoregulatory landscape of human tuberculosis granulomas

artículo científico publicado en 2022

Tissue-resident-like CD4+ T cells secreting IL-17 control Mycobacterium tuberculosis in the human lung

artículo científico

Turning the respiratory flexibility of Mycobacterium tuberculosis against itself

artículo científico publicado en 2016

Use of Telepathology to Facilitate COVID-19 Research and Education through an Online COVID-19 Autopsy Biorepository

artículo científico publicado en 2021

induces decelerated bioenergetic metabolism in human macrophages

artículo científico publicado en 2018

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