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Lista de obras de Douglas Easton

11q13 is a susceptibility locus for hormone receptor positive breast cancer

artículo científico publicado en 2012

19p13.1 is a triple-negative-specific breast cancer susceptibility locus

artículo científico publicado en 2012

2q36.3 is associated with prognosis for oestrogen receptor-negative breast cancer patients treated with chemotherapy

artículo científico publicado en 2014

4-Hydroxyandrostenedione in the prophylaxis of N-methyl-N-nitrosourea induced mammary tumourigenesis

artículo científico publicado en 1991

7q21-rs6964587 and breast cancer risk: an extended case-control study by the Breast Cancer Association Consortium

artículo científico publicado en 2011

9q31.2-rs865686 as a susceptibility locus for estrogen receptor-positive breast cancer: evidence from the Breast Cancer Association Consortium

artículo científico publicado en 2012

A 45-year follow-up of kindred 107 and the search for BRCA2

scientific article published on 01 January 1995

A Common Variant at the 14q32 Endometrial Cancer Risk Locus Activates AKT1 through YY1 Binding

scientific article published on June 2016

A Cross-Cancer Genetic Association Analysis of the DNA Repair and DNA Damage Signaling Pathways for Lung, Ovary, Prostate, Breast, and Colorectal Cancer

artículo científico publicado en 2015

A Large-Scale Analysis of Genetic Variants within Putative miRNA Binding Sites in Prostate Cancer

artículo científico publicado en 2015

A Mendelian randomization analysis of circulating lipid traits and breast cancer risk

artículo científico publicado en 2019

A Transcriptome-Wide Association Study Among 97,898 Women to Identify Candidate Susceptibility Genes for Epithelial Ovarian Cancer Risk

article

A combined analysis of genome-wide association studies in breast cancer

artículo científico publicado en 2010

A combined genomewide linkage scan of 1,233 families for prostate cancer-susceptibility genes conducted by the international consortium for prostate cancer genetics

artículo científico publicado en 2005

A common coding variant in CASP8 is associated with breast cancer risk

article

A common variant at the TERT-CLPTM1L locus is associated with estrogen receptor-negative breast cancer

artículo científico publicado en 2011

A common variant in BRCA2 is associated with both breast cancer risk and prenatal viability

artículo científico publicado en 2000

A comprehensive evaluation of interaction between genetic variants and use of menopausal hormone therapy on mammographic density

artículo científico publicado en 2015

A comprehensive examination of breast cancer risk loci in African American women

artículo científico publicado en 2014

A comprehensive model for familial breast cancer incorporating BRCA1, BRCA2 and other genes

artículo científico publicado en 2002

A double blind randomised clinical trial of adjuvant aminoglutethimide versus placebo given to post menopausal patients with histologically confirmed stage II breast cancer

artículo científico publicado en 1986

A full-likelihood method for the evaluation of causality of sequence variants from family data

artículo científico publicado en 2003

A genetic risk score to guide age-specific, personalized prostate cancer screening

A genetic risk score to personalize prostate cancer screening, applied to population data

scientific article published on 24 June 2020

A genetic study and meta-analysis of the genetic predisposition of prostate cancer in a Chinese population

artículo científico publicado en 2016

A genome wide linkage search for breast cancer susceptibility genes

artículo científico publicado en 2006

A genome-wide association scan (GWAS) for mean telomere length within the COGS project: identified loci show little association with hormone-related cancer risk

scientific article published on 29 July 2013

A genome-wide association scan on estrogen receptor-negative breast cancer

artículo científico publicado en 2010

A genome-wide association study identifies a new ovarian cancer susceptibility locus on 9p22.2.

artículo científico publicado en 2009

A genome-wide association study identifies a novel susceptibility locus for renal cell carcinoma on 12p11.23

artículo científico publicado en 2011

A genome-wide association study identifies susceptibility loci for ovarian cancer at 2q31 and 8q24.

artículo científico publicado en 2010

A genome-wide association study of early-onset breast cancer identifies PFKM as a novel breast cancer gene and supports a common genetic spectrum for breast cancer at any age.

artículo científico publicado en 2014

A genome-wide association study of prognosis in breast cancer

artículo científico publicado en 2010

A genome-wide association study of testicular germ cell tumor

artículo científico publicado en 2009

A genome-wide association study to identify genetic markers associated with endometrial cancer grade

artículo científico publicado en 2012

A genome-wide association study to identify genetic susceptibility loci that modify ductal and lobular postmenopausal breast cancer risk associated with menopausal hormone therapy use: a two-stage design with replication

scientific article published on 20 February 2013

A genomic approach to therapeutic target validation identifies a glucose-lowering GLP1R variant protective for coronary heart disease

artículo científico publicado en 2016

A germline mutation in the androgen receptor gene in two brothers with breast cancer and Reifenstein syndrome

artículo científico publicado en 1992

A hypermutation phenotype and somatic MSH6 mutations in recurrent human malignant gliomas after alkylator chemotherapy

artículo científico publicado en 2006

A large-scale assessment of two-way SNP interactions in breast cancer susceptibility using 46,450 cases and 42,461 controls from the breast cancer association consortium

artículo científico publicado en 2013

A linked genetic marker for multiple endocrine neoplasia type 2A on chromosome 10

scientific article published in Nature

A locus on 19p13 modifies risk of breast cancer in BRCA1 mutation carriers and is associated with hormone receptor-negative breast cancer in the general population

artículo científico publicado en 2010

A meta-analysis of 87,040 individuals identifies 23 new susceptibility loci for prostate cancer

artículo científico publicado en 2014

A meta-analysis of genome-wide association studies of breast cancer identifies two novel susceptibility loci at 6q14 and 20q11.

artículo científico publicado en 2012

A meta-analysis of genome-wide association studies to identify prostate cancer susceptibility loci associated with aggressive and non-aggressive disease

artículo científico publicado en 2012

A multicenter study of cancer incidence in CHEK2 1100delC mutation carriers

artículo científico publicado en 2006

A multilayered post-GWAS assessment on genetic susceptibility to pancreatic cancer

artículo científico publicado en 2021

A network analysis to identify mediators of germline-driven differences in breast cancer prognosis

artículo científico publicado en 2020

A nonsynonymous polymorphism in IRS1 modifies risk of developing breast and ovarian cancers in BRCA1 and ovarian cancer in BRCA2 mutation carriers

artículo científico publicado en 2012

A novel recurrent mutation in MITF predisposes to familial and sporadic melanoma

artículo científico publicado en 2011

A novel tumour-based test to identify breast cancer due to BRCA1 and BRCA2 mutations.

artículo científico publicado en 2010

A physical analysis of the Y chromosome shows no additional deletions, other than Gr/Gr, associated with testicular germ cell tumour

artículo científico publicado en 2007

A pilot study of compositional analysis of the breast and estimation of breast mammographic density using three-dimensional T1-weighted magnetic resonance imaging

artículo científico publicado en 2008

A polymorphism in the base excision repair gene PARP2 is associated with differential prognosis by chemotherapy among postmenopausal breast cancer patients

artículo científico publicado en 2015

A population study of mutations and LOH at breast cancer gene loci in tumours from sister pairs: two recurrent mutations seem to account for all BRCA1/BRCA2 linked breast cancer in Iceland

artículo científico publicado en 1998

A population-based audit of ethnicity and breast cancer risk in one general practice catchment area in North London, UK: implications for practice

scientific article published on 15 September 2007

A preliminary analysis of consortium data for markers tightly linked to multiple endocrine neoplasia type 2A.

artículo científico publicado en 1992

A prospective study of neurofibromatosis type 1 cancer incidence in the UK.

artículo científico publicado en 2006

A recurrent truncating germline mutation in the BRIP1/FANCJ gene and susceptibility to prostate cancer

scientific article published on 06 January 2009

A response to "Personalised medicine and population health: breast and ovarian cancer"

artículo científico publicado en 2019

A risk prediction algorithm based on family history and common genetic variants: application to prostate cancer with potential clinical impact

artículo científico publicado en 2011

A risk prediction algorithm for ovarian cancer incorporating BRCA1, BRCA2, common alleles and other familial effects

artículo científico publicado en 2015

A role for XRCC2 gene polymorphisms in breast cancer risk and survival

artículo científico publicado en 2011

A screen of the complete protein kinase gene family identifies diverse patterns of somatic mutations in human breast cancer

artículo científico publicado en 2005

A somatic-mutational process recurrently duplicates germline susceptibility loci and tissue-specific super-enhancers in breast cancers

artículo científico publicado en 2017

A survey of homozygous deletions in human cancer genomes

artículo científico publicado en 2005

A systematic genetic assessment of 1,433 sequence variants of unknown clinical significance in the BRCA1 and BRCA2 breast cancer-predisposition genes

artículo científico publicado en 2007

A systematic review and meta‐analysis of family history and risk of ovarian cancer

artículo científico publicado el 1 de mayo de 1998

A systematic review of genetic polymorphisms and breast cancer risk.

artículo científico publicado en 1999

A systematic, large-scale resequencing screen of X-chromosome coding exons in mental retardation

artículo científico publicado en 2009

A test of performance of breast MRI interpretation in a multicentre screening study

artículo científico publicado en 2006

A transcriptome-wide association study of 229,000 women identifies new candidate susceptibility genes for breast cancer

artículo científico publicado en 2018

A transforming growth factorbeta1 signal peptide variant increases secretion in vitro and is associated with increased incidence of invasive breast cancer.

artículo científico publicado en 2003

A weighted cohort approach for analysing factors modifying disease risks in carriers of high-risk susceptibility genes

scientific article published on 01 July 2005

AA9int: SNP interaction pattern search using non-hierarchical additive model set

ATM Mutations and Phenotypes in Ataxia-Telangiectasia Families in the British Isles: Expression of Mutant ATM and the Risk of Leukemia, Lymphoma, and Breast Cancer

artículo científico publicado el 1 de febrero de 1998

ATM mutations that cause ataxia-telangiectasia are breast cancer susceptibility alleles

artículo científico publicado en 2006

ATM polymorphisms as risk factors for prostate cancer development

artículo científico publicado en 2004

AURKA F31I polymorphism and breast cancer risk in BRCA1 and BRCA2 mutation carriers: a consortium of investigators of modifiers of BRCA1/2 study

artículo científico publicado en 2007

Absence of evidence for a familial breast cancer susceptibility gene at chromosome 8p12-p22

article

Absence of linkage to the ataxia telangiectasia locus in familial breast cancer

artículo científico publicado en 1993

Abstract 2030: The role of genetic variation in calcium-activated potassium channels in breast cancer patients treated with tamoxifen

artículo científico publicado en 2016

Abstract 4836: Gene and environment interactions of height and selected candidate SNPs in prostate cancer: results from the PRACTICAL consortium

artículo científico publicado en 2013

Abstract 5314: DNA methylation quantitative trait loci and breast cancer risk: Data from nearly 230,000 women of European descent

artículo científico publicado en 2018

Abstract LB-448: Genome-wide association study identifies new prostate cancer susceptibility loci

artículo científico publicado en 2011

Acute chemotherapy-related toxicity is not increased in BRCA1 and BRCA2 mutation carriers treated for breast cancer in the United Kingdom

artículo científico publicado en 2006

Adjuvant aminoglutethimide for postmenopausal patients with primary breast cancer: analysis at 8 years

artículo científico publicado el 1 de octubre de 1992

Adjuvant aminoglutethimide therapy for postmenopausal patients with primary breast cancer

scientific article published on 01 May 1987

After BRCA1 and BRCA2-what next? Multifactorial segregation analyses of three-generation, population-based Australian families affected by female breast cancer

artículo científico publicado en 2000

Age at menarche and menopause and breast cancer risk in the International BRCA1/2 Carrier Cohort Study

artículo científico publicado en 2007

Age- and Tumor Subtype-Specific Breast Cancer Risk Estimates for CHEK2*1100delC Carriers

artículo científico publicado en 2016

Alcohol Consumption, Cigarette Smoking, and Risk of Breast Cancer for BRCA1 and BRCA2 Mutation Carriers: Results from The BRCA1 and BRCA2 Cohort Consortium

scientific article published on 02 December 2019

Alcohol consumption and prostate cancer incidence and progression: A Mendelian randomisation study

artículo científico publicado en 2016

Alcohol consumption and survival after a breast cancer diagnosis: a literature-based meta-analysis and collaborative analysis of data for 29,239 cases

artículo científico publicado en 2014

Allele losses in the region 17q12-21 in familial breast and ovarian cancer involve the wild-type chromosome

artículo científico publicado el 1 de octubre de 1992

Allelic association of the human homologue of the mouse modifier Ptprj with breast cancer

artículo científico publicado en 2005

Allelotype of uterine leiomyomas

scientific article published on 01 October 1999

Alzheimer disease is not associated with polymorphisms in the angiotensinogen and renin genes

artículo científico publicado en 2001

An analysis of prognostic factors in early stage Hodgkin's disease

artículo científico publicado en 1986

An analysis of variation in expression of neurofibromatosis (NF) type 1 (NF1): evidence for modifying genes.

artículo científico publicado en 1993

An autosome-wide scan for linkage disequilibrium-based association in sporadic breast cancer cases in eastern Finland: three candidate regions found

artículo científico publicado en 2005

An intergenic risk locus containing an enhancer deletion in 2q35 modulates breast cancer risk by deregulating IGFBP5 expression

artículo científico publicado en 2016

An international initiative to identify genetic modifiers of cancer risk in BRCA1 and BRCA2 mutation carriers: the Consortium of Investigators of Modifiers of BRCA1 and BRCA2 (CIMBA)

artículo científico publicado en 2007

An investigation of ACE as a risk factor for dementia and cognitive decline in the general population.

artículo científico publicado en 2002

An original phylogenetic approach identified mitochondrial haplogroup T1a1 as inversely associated with breast cancer risk in BRCA2 mutation carriers

artículo científico publicado en 2015

Analysis and meta-analysis of two serotonin transporter gene polymorphisms in bipolar and unipolar affective disorders

artículo científico publicado el 7 de febrero de 1998

Analysis of Xq27-28 linkage in the international consortium for prostate cancer genetics (ICPCG) families

artículo científico publicado el 19 de junio de 2012

Analysis of alpha-1 antichymotrypsin, presenilin-1, angiotensin-converting enzyme, and methylenetetrahydrofolate reductase loci as candidates for dementia

artículo científico publicado en 1997

Analysis of single-nucleotide polymorphisms in the interleukin-4 receptor gene for association with inflammatory bowel disease

article

Analysis of the DND1 gene in men with sporadic and familial testicular germ cell tumors

artículo científico publicado en 2008

Analysis of the apo E/apo C-I, angiotensin converting enzyme and methylenetetrahydrofolate reductase genes as candidates affecting human longevity.

artículo científico publicado en 1997

Analysis of the contribution of HLA genes to genetic predisposition in inflammatory bowel disease

artículo científico publicado en 1996

Analysis of the genetic phylogeny of multifocal prostate cancer identifies multiple independent clonal expansions in neoplastic and morphologically normal prostate tissue

artículo científico publicado en 2015

Androgen receptor polymorphisms: Association with prostate cancer risk, relapse and overall survival

artículo científico publicado en 1999

Annexin A1 expression in a pooled breast cancer series: association with tumor subtypes and prognosis

artículo científico publicado en 2015

Apo E and Apo CI loci are associated with dementia in younger but not older late-onset cases

artículo científico publicado en 1998

Apo E genotypes and risk of dementia in Down syndrome

artículo científico publicado en 1999

Apolipoprotein E genetic variation and Alzheimer's disease. a meta-analysis

artículo científico publicado en 1999

Apolipoprotein E4 is only a weak predictor of dementia and cognitive decline in the general population

artículo científico publicado en 2002

Apoptosis, ageing and cancer susceptibility.

artículo científico publicado en 2003

Apparent human BRCA1 knockout caused by mispriming during polymerase chain reaction: implications for genetic testing

scientific article published on 01 May 2001

Application of linked DNA markers to screening families with multiple endocrine neoplasia type 2A

scientific article published on 01 April 1990

Application of minisatellite DNA probes to linkage in MEN-2

scientific article published on 01 January 1987

Area and volumetric density estimation in processed full-field digital mammograms for risk assessment of breast cancer

artículo científico publicado en 2014

Assessing associations between the AURKA-HMMR-TPX2-TUBG1 functional module and breast cancer risk in BRCA1/2 mutation carriers

artículo científico publicado en 2015

Assessing interactions between the associations of common genetic susceptibility variants, reproductive history and body mass index with breast cancer risk in the breast cancer association consortium: a combined case-control study

artículo científico publicado en 2010

Assessing the role of insulin-like growth factors and binding proteins in prostate cancer using Mendelian randomization: Genetic variants as instruments for circulating levels

artículo científico publicado en 2016

Assessing the usefulness of a novel MRI-based breast density estimation algorithm in a cohort of women at high genetic risk of breast cancer: the UK MARIBS study

artículo científico publicado en 2009

Assessment of interactions between 205 breast cancer susceptibility loci and 13 established risk factors in relation to breast cancer risk, in the Breast Cancer Association Consortium

scientific article published on 01 February 2020

Assessment of polygenic architecture and risk prediction based on common variants across fourteen cancers

artículo científico publicado en 2020

Assessment of variation in immunosuppressive pathway genes reveals TGFBR2 to be associated with prognosis of estrogen receptor-negative breast cancer after chemotherapy

artículo científico publicado en 2015

Assessment of variation in immunosuppressive pathway genes reveals TGFBR2 to be associated with risk of clear cell ovarian cancer

artículo científico publicado en 2016

Association analyses identify 31 new risk loci for colorectal cancer susceptibility

artículo científico publicado en 2019

Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci

artículo científico publicado en 2018

Association analysis identifies 65 new breast cancer risk loci.

artículo científico publicado en 2017

Association analysis of 9,560 prostate cancer cases from the International Consortium of Prostate Cancer Genetics confirms the role of reported prostate cancer associated SNPs for familial disease

artículo científico publicado en 2013

Association between Adult Height and Risk of Colorectal, Lung, and Prostate Cancer: Results from Meta-analyses of Prospective Studies and Mendelian Randomization Analyses

artículo científico publicado en 2016

Association between BRCA1 and BRCA2 mutations and survival in women with invasive epithelial ovarian cancer

artículo científico publicado en 2012

Association between Prostinogen (KLK15) genetic variants and prostate cancer risk and aggressiveness in Australia and a meta-analysis of GWAS data

artículo científico publicado en 2011

Association between a germline OCA2 polymorphism at chromosome 15q13.1 and estrogen receptor-negative breast cancer survival

artículo científico publicado en 2010

Association between common germline genetic variation in 94 candidate genes or regions and risks of invasive epithelial ovarian cancer

artículo científico publicado en 2009

Association between common variation in 120 candidate genes and breast cancer risk

artículo científico publicado en 2007

Association between invasive ovarian cancer susceptibility and 11 best candidate SNPs from breast cancer genome-wide association study

artículo científico publicado en 2009

Association between leptin receptor gene polymorphisms and early-onset prostate cancer

article

Association between the GCG polymorphism of the selenium dependent GPX1 gene and the risk of young onset prostate cancer

artículo científico publicado en 2002

Association of ESR1 gene tagging SNPs with breast cancer risk

artículo científico publicado en 2009

Association of Genomic Domains in BRCA1 and BRCA2 with Prostate Cancer Risk and Aggressiveness

artículo científico publicado en 2019

Association of PHB 1630 C>T and MTHFR 677 C>T polymorphisms with breast and ovarian cancer risk in BRCA1/2 mutation carriers: results from a multicenter study

artículo científico publicado en 2012

Association of a common AKAP9 variant with breast cancer risk: a collaborative analysis

artículo científico publicado en 2008

Association of breast cancer risk in BRCA1 and BRCA2 mutation carriers with genetic variants showing differential allelic expression: identification of a modifier of breast cancer risk at locus 11q22.3.

artículo científico publicado en 2016

Association of breast cancer risk with genetic variants showing differential allelic expression: Identification of a novel breast cancer susceptibility locus at 4q21.

scientific article published on 21 October 2016

Association of folate-pathway gene polymorphisms with the risk of prostate cancer: a population-based nested case-control study, systematic review, and meta-analysis

artículo científico publicado en 2009

Association of genetic susceptibility variants for type 2 diabetes with breast cancer risk in women of European ancestry

artículo científico publicado en 2016

Association of germline genetic variants with breast cancer-specific survival in patient subgroups defined by clinic-pathological variables related to tumor biology and type of systemic treatment

artículo científico publicado en 2021

Association of germline variation with the survival of women with BRCA1/2 pathogenic variants and breast cancer

scientific article published on 10 September 2020

Association of single-nucleotide polymorphisms in the cell cycle genes with breast cancer in the British population

artículo científico publicado en 2008

Association of tamoxifen use and reduced risk of contralateral breast cancer for BRCA1 and BRCA2 mutation carriers

artículo científico publicado en 2012

Association of the Progesterone Receptor Gene with Breast Cancer Risk: A Single-Nucleotide Polymorphism Tagging Approach

article

Association of the variants CASP8 D302H and CASP10 V410I with breast and ovarian cancer risk in BRCA1 and BRCA2 mutation carriers

artículo científico publicado en 2010

Association of type and location of BRCA1 and BRCA2 mutations with risk of breast and ovarian cancer

artículo científico publicado en 2015

Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants

artículo científico publicado en 2007

Association studies for finding cancer-susceptibility genetic variants

artículo científico publicado en 2004

Association study of prostate cancer susceptibility variants with risks of invasive ovarian, breast, and colorectal cancer

artículo científico publicado en 2008

Associations among Mammographic Density, Circulating Sex Hormones, and Polymorphisms in Sex Hormone Metabolism Genes in Postmenopausal Women

article

Associations of a Breast Cancer Polygenic Risk Score With Tumor Characteristics and Survival

scholarly article

Associations of breast cancer risk factors with tumor subtypes: a pooled analysis from the Breast Cancer Association Consortium studies

artículo científico publicado en 2010

Associations of common breast cancer susceptibility alleles with risk of breast cancer subtypes in BRCA1 and BRCA2 mutation carriers

artículo científico publicado en 2014

Associations of common variants at 1p11.2 and 14q24.1 (RAD51L1) with breast cancer risk and heterogeneity by tumor subtype: findings from the Breast Cancer Association Consortium

artículo científico publicado en 2011

Associations of obesity and circulating insulin and glucose with breast cancer risk: a Mendelian randomization analysis

article by Xiang Shu et al published 1 October 2018 in International Journal of Epidemiology

Atlas of prostate cancer heritability in European and African-American men pinpoints tissue-specific regulation

artículo científico publicado en 2016

Author Correction: Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci

scholarly article published in Nature Genetics

Author Correction: Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci

scholarly article published in Nature Genetics

Author Correction: Genome-wide association study identifies susceptibility loci for B-cell childhood acute lymphoblastic leukemia

scientific article published in Nature Communications

Author Correction: Genome-wide association study of classical Hodgkin lymphoma identifies key regulators of disease susceptibility

artículo científico publicado en 2019

Author Correction: Germline variation at 8q24 and prostate cancer risk in men of European ancestry

scientific article published in Nature Communications

Author Correction: Identification of multiple risk loci and regulatory mechanisms influencing susceptibility to multiple myeloma

artículo científico publicado en 2019

Author Correction: The evolutionary history of lethal metastatic prostate cancer

artículo científico publicado en 2020

Authors' response: Associations of obesity and circulating insulin and glucose with breast cancer risk

artículo científico publicado en 2019

Average age-specific cumulative risk of breast cancer according to type and site of germline mutations in BRCA1 and BRCA2 estimated from multiple-case breast cancer families attending Australian family cancer clinics

artículo científico publicado en 2003

Average risks of breast and ovarian cancer associated with BRCA1 or BRCA2 mutations detected in case Series unselected for family history: a combined analysis of 22 studies

artículo científico publicado en 2003

BOADICEA breast cancer risk prediction model: updates to cancer incidences, tumour pathology and web interface

artículo científico publicado en 2013

BOADICEA: a comprehensive breast cancer risk prediction model incorporating genetic and nongenetic risk factors

scientific article published on 15 January 2019

BRCA Challenge: BRCA Exchange as a global resource for variants in BRCA1 and BRCA2

artículo científico publicado en 2018

BRCA1 and BRCA2 Cancer Risks

BRCA1 and BRCA2 Pathogenic Sequence Variants in Women of African Origin or Ancestry

artículo científico publicado en 2019

BRCA1 and BRCA2 mutation predictions using the BOADICEA and BRCAPRO models and penetrance estimation in high-risk French-Canadian families

artículo científico publicado en 2005

BRCA1 and BRCA2 mutations in a population-based study of male breast cancer

artículo científico publicado en 2002

BRCA1, BRCA2 and pedigree genetic analysis to determine genetic risk in the UK Royal Marsden Hospital tamoxifen prevention trial.

artículo científico publicado en 2000

BRCA1/BRCA2 mutation status and analysis of cancer family history in participants of the Royal Marsden Hospital tamoxifen chemoprevention trial

article

BRCA2 Hypomorphic Missense Variants Confer Moderate Risks of Breast Cancer

artículo científico publicado en 2017

BRCA2 Polymorphic Stop Codon K3326X and the Risk of Breast, Prostate, and Ovarian Cancers

artículo científico publicado en 2015

BRCA2 arg372hispolymorphism and epithelial ovarian cancer risk

article

BRCA2 is a moderate penetrance gene contributing to young-onset prostate cancer: implications for genetic testing in prostate cancer patients

artículo científico publicado en 2011

Basal-like grade III invasive ductal carcinoma of the breast: patterns of metastasis and long-term survival

artículo científico publicado en 2007

Blood lipids and prostate cancer: a Mendelian randomization analysis

artículo científico publicado en 2016

Body mass index and breast cancer survival: a Mendelian randomization analysis

artículo científico publicado en 2017

Bone marrow micrometastases in primary breast cancer: Prognostic significance after 6 years' follow-up

artículo científico publicado el 1 de enero de 1991

Breast Cancer Polygenic Risk Score and Contralateral Breast Cancer Risk

artículo científico publicado en 2020

Breast and Prostate Cancer Risks for Male BRCA1 and BRCA2 Pathogenic Variant Carriers Using Polygenic Risk Scores

artículo científico publicado en 2022

Breast and ovarian cancer incidence in BRCA1-mutation carriers. Breast Cancer Linkage Consortium.

artículo científico publicado en 1995

Breast and ovarian cancer risks in a large series of clinically ascertained families with a high proportion of BRCA1 and BRCA2 Dutch founder mutations

artículo científico publicado en 2013

Breast and ovarian cancer risks to carriers of the BRCA1 5382insC and 185delAG and BRCA2 6174delT mutations: a combined analysis of 22 population based studies

artículo científico publicado en 2005

Breast cancer risk and 6q22.33: combined results from Breast Cancer Association Consortium and Consortium of Investigators on Modifiers of BRCA1/2

artículo científico publicado en 2012

Breast cancer risk factors and their effects on survival: a Mendelian randomisation study

artículo científico publicado en 2020

Breast cancer risk variants at 6q25 display different phenotype associations and regulate ESR1, RMND1 and CCDC170.

artículo científico publicado en 2016

Breast cancer risks for BRCA1/2 carriers

artículo científico publicado en 2004

Breast cancer screening: time to target women at risk

artículo científico publicado el 6 de junio de 2013

Breast cancer susceptibility polymorphisms and endometrial cancer risk: a Collaborative Endometrial Cancer Study

artículo científico publicado en 2011

Breast cancer susceptibility risk associations and heterogeneity by E-cadherin tumor tissue expression

artículo científico publicado en 2013

Breast-Cancer Risk in Families With Mutations in PALB2

Breast-cancer risk in families with mutations in PALB2

artículo científico publicado en 2014

CAG and GGC repeat polymorphisms in the androgen receptor gene and breast cancer susceptibility in BRCA1/2 carriers and non-carriers

artículo científico publicado en 2001

CHEK2 variant I157T may be associated with increased breast cancer risk

artículo científico publicado en 2004

CHEK2*1100delC heterozygosity in women with breast cancer associated with early death, breast cancer-specific death, and increased risk of a second breast cancer

artículo científico publicado en 2012

CHEK2, MGMT, SULT1E1 and SULT1A1 polymorphisms and endometrial cancer risk

artículo científico publicado en 2011

COMPLEXO: identifying the missing heritability of breast cancer via next generation collaboration

artículo científico publicado en 2013

CYP17 promoter polymorphism and breast cancer in Australian women under age forty years

scientific article published on 01 October 2000

CYP19A1 fine-mapping and Mendelian randomization: estradiol is causal for endometrial cancer

artículo científico publicado en 2015

CanRisk Tool - A web interface for the prediction of breast and ovarian cancer risk and the likelihood of carrying genetic pathogenic variants

scientific article published on 17 December 2020

Cancer Incidence in BRCA1 mutation carriers

artículo científico publicado en 2002

Cancer Risks Associated With Germline PALB2 Pathogenic Variants: An International Study of 524 Families

artículo científico publicado en 2019

Cancer Risks Associated With and Pathogenic Variants

artículo científico publicado en 2022

Cancer Risks in Two Large Breast Cancer Families Linked to BRCA2 on Chromosome 13q12‐13

artículo científico publicado el 1 de julio de 1997

Cancer incidence in relatives of British Fanconi Anaemia patients

artículo científico publicado en 2008

Cancer mortality in relatives of women with breast cancer: the OPCS Study. Office of Population Censuses and Surveys

artículo científico publicado en 1996

Cancer mortality in relatives of women with ovarian cancer: the OPCS Study. Office of Population Censuses and Surveys

artículo científico publicado en 1996

Cancer mortality in the first degree relatives of young breast cancer patients

artículo científico publicado en 1992

Cancer risks and mortality in heterozygous ATM mutation carriers

artículo científico publicado en 2005

Cancer risks for BRCA1 and BRCA2 mutation carriers: results from prospective analysis of EMBRACE.

artículo científico publicado en 2013

Cancer risks in A-T heterozygotes

artículo científico publicado en 1994

Cancer treatment trials--past failures, current progress and future prospects.

artículo científico publicado en 1989

Cancers of the respiratory tract in mustard gas workers

artículo científico publicado en 1988

Candidate Causal Variants at the 8p12 Breast Cancer Risk Locus Regulate DUSP4

artículo científico publicado en 2020

Candidate genetic modifiers for breast and ovarian cancer risk in BRCA1 and BRCA2 mutation carriers

artículo científico publicado en 2014

Candidate locus analysis of the TERT-CLPTM1L cancer risk region on chromosome 5p15 identifies multiple independent variants associated with endometrial cancer risk

artículo científico publicado en 2015

Changing distribution of adenocarcinoma of the stomach

artículo científico publicado en 1987

Characterisation of PALB2 tumours through whole-exome and whole-transcriptomic analyses

artículo científico publicado en 2021

Characterization of the Cancer Spectrum in Men With Germline BRCA1 and BRCA2 Pathogenic Variants: Results From the Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA)

artículo científico publicado en 2020

Chromatin interactome mapping at 139 independent breast cancer risk signals

artículo científico publicado en 2020

Chromosomes 4 and 8 implicated in a genome wide SNP linkage scan of 762 prostate cancer families collected by the ICPCG

artículo científico publicado en 2011

Cis-eQTL analysis and functional validation of candidate susceptibility genes for high-grade serous ovarian cancer

artículo científico publicado en 2015

ClinGen and Genetic Testing

artículo científico publicado en 2015

Clinical implications of family history of prostate cancer and genetic risk single nucleotide polymorphism (SNP) profiles in an active surveillance cohort

artículo científico publicado en 2013

Clinical presentation as a predictor of laparotomy findings in supradiaphragmatic stage I and II Hodgkin's disease

artículo científico publicado en 1986

Clinical software development for the Web: lessons learned from the BOADICEA project

artículo científico publicado el 10 de abril de 2012

Clinicians' use of breast cancer risk assessment tools according to their perceived importance of breast cancer risk factors: an international survey

artículo científico publicado en 2018

Combined associations of a polygenic risk score and classical risk factors with breast cancer risk

artículo científico publicado en 2020

Combined effects of single nucleotide polymorphisms TP53 R72P and MDM2 SNP309, and p53 expression on survival of breast cancer patients

artículo científico publicado en 2009

Combined genetic and splicing analysis of BRCA1 c.[594-2A>C; 641A>G] highlights the relevance of naturally occurring in-frame transcripts for developing disease gene variant classification algorithms

scientific article published on 23 March 2016

Combined quantitative measures of ER, PR, HER2, and KI67 provide more prognostic information than categorical combinations in luminal breast cancer.

artículo científico publicado en 2019

Common BRCA1 variants and susceptibility to breast and ovarian cancer in the general population

artículo científico publicado en 1997

Common ERBB2 polymorphisms and risk of breast cancer in a white British population: a case-control study

artículo científico publicado en 2005

Common Genetic Variation In Cellular Transport Genes and Epithelial Ovarian Cancer (EOC) Risk

artículo científico publicado en 2015

Common Genetic Variation in Circadian Rhythm Genes and Risk of Epithelial Ovarian Cancer (EOC).

artículo científico publicado en 2015

Common Polymorphisms in ERCC2 (Xeroderma pigmentosum D) are not Associated with Breast Cancer Risk

scientific article published on 01 July 2005

Common Variants in RB1 Gene and Risk of Invasive Ovarian Cancer

article

Common alleles at 6q25.1 and 1p11.2 are associated with breast cancer risk for BRCA1 and BRCA2 mutation carriers

artículo científico publicado en 2011

Common breast cancer susceptibility alleles and the risk of breast cancer for BRCA1 and BRCA2 mutation carriers: implications for risk prediction

artículo científico publicado en 2010

Common breast cancer susceptibility alleles are associated with tumour subtypes in BRCA1 and BRCA2 mutation carriers: results from the Consortium of Investigators of Modifiers of BRCA1/2.

artículo científico publicado en 2011

Common breast cancer susceptibility loci are associated with triple-negative breast cancer

artículo científico publicado en 2011

Common breast cancer susceptibility variants in LSP1 and RAD51L1 are associated with mammographic density measures that predict breast cancer risk

artículo científico publicado en 2012

Common breast cancer-predisposition alleles are associated with breast cancer risk in BRCA1 and BRCA2 mutation carriers

artículo científico publicado en 2008

Common genetic determinants of breast-cancer risk in East Asian women: a collaborative study of 23 637 breast cancer cases and 25 579 controls

artículo científico publicado en 2013

Common genetic variants and modification of penetrance of BRCA2-associated breast cancer

artículo científico publicado en 2010

Common genetic variants associated with disease from genome-wide association studies are mutually exclusive in prostate cancer and rheumatoid arthritis

artículo científico publicado en 2012

Common genetic variation at BARD1 is not associated with breast cancer risk in BRCA1 or BRCA2 mutation carriers

artículo científico publicado en 2011

Common genetic variation in candidate genes and susceptibility to subtypes of breast cancer

artículo científico publicado en 2009

Common germline genetic variation in antioxidant defense genes and survival after diagnosis of breast cancer

artículo científico publicado en 2007

Common germline polymorphisms associated with breast cancer-specific survival

artículo científico publicado en 2015

Common germline polymorphisms in COMT, CYP19A1, ESR1, PGR, SULT1E1 and STS and survival after a diagnosis of breast cancer

artículo científico publicado en 2009

Common germline variation in mismatch repair genes and survival after a diagnosis of colorectal cancer

article

Common non-synonymous SNPs associated with breast cancer susceptibility: findings from the Breast Cancer Association Consortium

artículo científico publicado en 2014

Common polymorphisms in checkpoint kinase 2 are not associated with breast cancer risk

artículo científico publicado en 2003

Common polymorphisms in the prostaglandin pathway genes and their association with breast cancer susceptibility and survival

artículo científico publicado en 2009

Common single-nucleotide polymorphisms in DNA double-strand break repair genes and breast cancer risk

artículo científico publicado en 2008

Common susceptibility loci for male breast cancer

artículo científico publicado en 2020

Common variants associated with breast cancer in genome-wide association studies are modifiers of breast cancer risk in BRCA1 and BRCA2 mutation carriers

artículo científico publicado en 2010

Common variants at 12p11, 12q24, 9p21, 9q31.2 and in ZNF365 are associated with breast cancer risk for BRCA1 and/or BRCA2 mutation carriers

artículo científico publicado en 2012

Common variants at 19p13 are associated with susceptibility to ovarian cancer

artículo científico publicado en 2010

Common variants at the 19p13.1 and ZNF365 loci are associated with ER subtypes of breast cancer and ovarian cancer risk in BRCA1 and BRCA2 mutation carriers

artículo científico publicado en 2012

Common variants at the CHEK2 gene locus and risk of epithelial ovarian cancer

artículo científico publicado en 2015

Common variants in LSP1, 2q35 and 8q24 and breast cancer risk for BRCA1 and BRCA2 mutation carriers

scientific article published on 05 August 2009

Common variants in ZNF365 are associated with both mammographic density and breast cancer risk

artículo científico publicado en 2011

Common variants in breast cancer risk loci predispose to distinct tumor subtypes

artículo científico publicado en 2022

Common variants in mismatch repair genes and risk of colorectal cancer

article

Common variants in mismatch repair genes and risk of invasive ovarian cancer

artículo científico publicado en 2006

Common variants in the ATM, BRCA1, BRCA2, CHEK2 and TP53 cancer susceptibility genes are unlikely to increase breast cancer risk

artículo científico publicado en 2007

Common variants of the BRCA1 wild-type allele modify the risk of breast cancer in BRCA1 mutation carriers

artículo científico publicado en 2011

Common variation in EMSY and risk of breast and ovarian cancer: a case-control study using HapMap tagging SNPs

artículo científico publicado en 2005

Common variation in Kallikrein genes KLK5, KLK6, KLK12, and KLK13 and risk of prostate cancer and tumor aggressiveness

article

Common variation near CDKN1A, POLD3 and SHROOM2 influences colorectal cancer risk

artículo científico publicado en 2012

Comparison of 6q25 breast cancer hits from Asian and European Genome Wide Association Studies in the Breast Cancer Association Consortium (BCAC)

artículo científico publicado en 2012

Comparison of conservative surgery and radiotherapy with mastectomy in the treatment of early breast cancer

scientific article published on 01 December 1990

Compelling evidence for a prostate cancer gene at 22q12.3 by the International Consortium for Prostate Cancer Genetics

artículo científico publicado en 2007

Comprehensive Functional Characterization and Clinical Interpretation of 20 Splice-Site Variants of the <i>RAD51C</i> Gene

artículo científico publicado en 2020

Comprehensive functional annotation of 77 prostate cancer risk loci

artículo científico publicado en 2014

Comprehensive genetic assessment of the ESR1 locus identifies a risk region for endometrial cancer

artículo científico publicado en 2015

Confirmation of 5p12 as a susceptibility locus for progesterone-receptor-positive, lower grade breast cancer

artículo científico publicado en 2011

Consistent loss of the wild type allele in breast cancers from a family linked to the BRCA2 gene on chromosome 13q12-13.

artículo científico publicado en 1995

Consortium analysis of 7 candidate SNPs for ovarian cancer

scientific article published on July 2008

Constitutional mutation in exon 8 of the p53 gene in a patient with multiple primary tumours: molecular and immunohistochemical findings

article

Contribution of BRCA1 and BRCA2 germ-line mutations to the incidence of breast cancer in young women: results from a prospective population-based study in France

artículo científico publicado en 2005

Contribution of BRCA1 mutations to ovarian cancer

artículo científico publicado en 1997

Contribution of germline mutations in BRCA2, P16(INK4A), P14(ARF) and P15 to uveal melanoma

artículo científico publicado en 2003

Correction to: Clinicians' use of breast cancer risk assessment tools according to their perceived importance of breast cancer risk factors: an international survey

scientific article published on 01 October 2019

Correction to: Genetic variant predictors of gene expression provide new insight into risk of colorectal cancer

scientific article published on 01 July 2019

Correction to: Risk-reducing salpingo-oophorectomy, natural menopause, and breast cancer risk: an international prospective cohort of BRCA1 and BRCA2 mutation carriers

artículo científico publicado en 2020

Correction: BOADICEA: a comprehensive breast cancer risk prediction model incorporating genetic and nongenetic risk factors

scientific article published on 01 June 2019

Correction: Common Genetic Variants and Modification of Penetrance of BRCA2-Associated Breast Cancer

scholarly article by Mia M Gaudet published in November 2010

Correction: Common Genetic Variants and Modification of Penetrance of BRCA2-Associated Breast Cancer.

artículo científico publicado en 2010

Correction: Comparison of 6q25 Breast Cancer Hits from Asian and European Genome Wide Association Studies in the Breast Cancer Association Consortium (BCAC)

artículo científico publicado en 2012

Correction: Evaluating Genome-Wide Association Study-Identified Breast Cancer Risk Variants in African-American Women.

artículo científico publicado en 2014

Corrections to: Use of the BOADICEA Web Application in clinical practice: appraisals by clinicians from various countries.

artículo científico publicado en 2017

Corrigendum re “Genetic Variants Related to Longer Telomere Length are Associated with Increased Risk of Renal Cell Carcinoma” [Eur Urol 2017;72:747–54]

scholarly article published in European Urology

Corrigendum: A somatic-mutational process recurrently duplicates germline susceptibility loci and tissue-specific super-enhancers in breast cancers

artículo científico publicado en 2017

Corrigendum: Rare coding variants and X-linked loci associated with age at menarche

artículo científico publicado en 2015

Cost-effectiveness of screening with contrast enhanced magnetic resonance imaging vs X-ray mammography of women at a high familial risk of breast cancer

artículo científico publicado en 2006

Critical assessment of new risk factors for breast cancer: considerations for development of an improved risk prediction model

artículo científico publicado en 2007

Critical research gaps and translational priorities for the successful prevention and treatment of breast cancer

artículo científico publicado en 2013

Cross Cancer Genomic Investigation of Inflammation Pathway for Five Common Cancers: Lung, Ovary, Prostate, Breast, and Colorectal Cancer

artículo científico publicado en 2015

Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations

artículo científico publicado en 2016

Crowdsourcing the General Public for Large Scale Molecular Pathology Studies in Cancer

artículo científico publicado en 2015

Cumulative Burden of Colorectal Cancer-Associated Genetic Variants Is More Strongly Associated With Early-Onset vs Late-Onset Cancer

scientific article published on 19 December 2019

DNA glycosylases involved in base excision repair may be associated with cancer risk in BRCA1 and BRCA2 mutation carriers

artículo científico publicado en 2014

DNA mismatch repair gene MSH6 implicated in determining age at natural menopause

scientific article published on 19 December 2013

Decreased breast cancer risk in systemic lupus erythematosus: the search for a genetic basis continues

artículo científico publicado en 2012

Detecting rare copy number variants from Illumina genotyping arrays with the CamCNV pipeline: Segmentation of z-scores improves detection and reliability

scientific article published on 05 October 2020

Diagnostic radiation procedures and risk of prostate cancer

artículo científico publicado en 2008

Dietary fat and early-onset prostate cancer risk

artículo científico publicado en 2010

Differential Burden of Rare and Common Variants on Tumor Characteristics, Survival, and Mode of Detection in Breast Cancer

article published in 2018

Discovery of common and rare genetic risk variants for colorectal cancer

artículo científico publicado en 2018

Do MDM2 SNP309 and TP53 R72P interact in breast cancer susceptibility? A large pooled series from the breast cancer association consortium

artículo científico publicado en 2007

E-cadherin breast tumor expression, risk factors and survival: Pooled analysis of 5,933 cases from 12 studies in the Breast Cancer Association Consortium.

artículo científico publicado en 2018

Educational attainment and mean leukocyte telomere length in women in the European Prospective Investigation into Cancer (EPIC)-Norfolk population study

artículo científico publicado en 2011

Effect of BRCA Mutations on Metastatic Relapse and Cause-specific Survival After Radical Treatment for Localised Prostate Cancer

artículo científico publicado en 2014

Effect of chest X-rays on the risk of breast cancer among BRCA1/2 mutation carriers in the international BRCA1/2 carrier cohort study: a report from the EMBRACE, GENEPSO, GEO-HEBON, and IBCCS Collaborators' Group

artículo científico publicado en 2006

Effect of germ-line genetic variation on breast cancer survival in a population-based study

artículo científico publicado en 2002

Effects of BRCA2 cis-regulation in normal breast and cancer risk amongst BRCA2 mutation carriers

artículo científico publicado en 2012

Effects of common germ-line genetic variation in cell cycle genes on ovarian cancer survival

artículo científico publicado en 2008

Effects of common germline genetic variation in cell cycle control genes on breast cancer survival: results from a population-based cohort

artículo científico publicado en 2008

Elevated expression of Ki-67 identifies aggressive prostate cancers but does not distinguish BRCA1 or BRCA2 mutation carriers

scientific article published on 01 February 2010

Eligibility for magnetic resonance imaging screening in the United Kingdom: effect of strict selection criteria and anonymous DNA testing on breast cancer incidence in the MARIBS Study

artículo científico publicado en 2009

Endometrial cancer and genetic variation in PTEN, PIK3CA, AKT1, MLH1, and MSH2 within a population-based case-control study

artículo científico publicado en 2010

Epidemiological and ES cell-based Functional Evaluation of BRCA2 Variants Identified in Families with Breast Cancer

artículo científico publicado en 2020

Epigenetic analysis leads to identification of HNF1B as a subtype-specific susceptibility gene for ovarian cancer

artículo científico publicado en 2013

Epithelial-Mesenchymal Transition (EMT) Gene Variants and Epithelial Ovarian Cancer (EOC) Risk

artículo científico publicado en 2015

Erratum: Corrigendum: A common coding variant in CASP8 is associated with breast cancer risk

scholarly article published in Nature Genetics

Erratum: Corrigendum: Analysis of the genetic phylogeny of multifocal prostate cancer identifies multiple independent clonal expansions in neoplastic and morphologically normal prostate tissue

scholarly article by Colin S Cooper et al published June 2015 in Nature Genetics

Erratum: Corrigendum: Common variants at 19p13 are associated with susceptibility to ovarian cancer

scholarly article published in Nature Genetics

Erratum: Corrigendum: Genome-wide association study identifies multiple loci associated with both mammographic density and breast cancer risk

scientific article published in Nature Communications

Erratum: Identification of the breast cancer susceptibility gene BRCA2

artículo científico publicado en 1996

Estimates of the gene frequency of BRCA1 and its contribution to breast and ovarian cancer incidence

artículo científico publicado en 1995

Etiology of hormone receptor positive breast cancer differs by levels of histologic grade and proliferation

artículo científico publicado en 2018

European polygenic risk score for prediction of breast cancer shows similar performance in Asian women

artículo científico publicado en 2020

Evaluating clinician acceptability of the prototype CanRisk tool for predicting risk of breast and ovarian cancer: A multi-methods study

artículo científico publicado en 2020

Evaluating genetic risk for prostate cancer among Japanese and Latinos

artículo científico publicado en 2012

Evaluating genetic variants associated with breast cancer risk in high and moderate-penetrance genes in Asians

artículo científico publicado en 2017

Evaluating genome-wide association study-identified breast cancer risk variants in African-American women

artículo científico publicado en 2013

Evaluating the effectiveness of using standard mammogram form to predict breast cancer risk: case-control study

artículo científico publicado en 2008

Evaluating the power to discriminate between highly correlated SNPs in genetic association studies

scientific article published on 01 July 2010

Evaluating the role of alcohol consumption in breast and ovarian cancer susceptibility using population-based cohort studies and two-sample Mendelian randomization analyses

scientific article published on 25 September 2020

Evaluation of BRCA1 and BRCA2 mutation prevalence, risk prediction models and a multistep testing approach in French-Canadian families with high risk of breast and ovarian cancer

artículo científico publicado en 2006

Evaluation of Fanconi Anemia genes in familial breast cancer predisposition

article

Evaluation of Polygenic Risk Scores for Breast and Ovarian Cancer Risk Prediction in BRCA1 and BRCA2 Mutation Carriers

artículo científico publicado en 2017

Evaluation of a candidate breast cancer associated SNP in ERCC4 as a risk modifier in BRCA1 and BRCA2 mutation carriers. Results from the Consortium of Investigators of Modifiers of BRCA1/BRCA2 (CIMBA).

artículo científico publicado en 2009

Evaluation of a prospective scoring system designed for a multicenter breast MR imaging screening study

artículo científico publicado en 2006

Evaluation of an algorithm of tagging SNPs selection by linkage disequilibrium

artículo científico publicado en 2006

Evaluation of association methods for analysing modifiers of disease risk in carriers of high-risk mutations

artículo científico publicado en 2012

Evaluation of association of HNF1B variants with diverse cancers: collaborative analysis of data from 19 genome-wide association studies

artículo científico publicado en 2010

Evaluation of associations between genetically predicted circulating protein biomarkers and breast cancer risk

artículo científico publicado en 2019

Evaluation of chromosome 6p22 as a breast cancer risk modifier locus in a follow-up study of BRCA2 mutation carriers

artículo científico publicado en 2012

Evaluation of linkage of breast cancer to the putative BRCA3 locus on chromosome 13q21 in 128 multiple case families from the Breast Cancer Linkage Consortium

artículo científico publicado en 2002

Evaluation of the XRCC1 gene as a phenotypic modifier in BRCA1/2 mutation carriers. Results from the consortium of investigators of modifiers of BRCA1/BRCA2.

artículo científico publicado en 2011

Evaluation of variation in the phosphoinositide-3-kinase catalytic subunit alpha oncogene and breast cancer risk

artículo científico publicado en 2011

Evidence for SMAD3 as a modifier of breast cancer risk in BRCA2 mutation carriers

artículo científico publicado en 2010

Evidence for further breast cancer susceptibility genes in addition to BRCA1 and BRCA2 in a population-based study

artículo científico publicado en 2001

Evidence of a Causal Association Between Insulinemia and Endometrial Cancer: A Mendelian Randomization Analysis

artículo científico publicado en 2015

Evidence of gene-environment interactions between common breast cancer susceptibility loci and established environmental risk factors

artículo científico publicado en 2013

Evidence of linkage of the inflammatory bowel disease susceptibility locus on chromosome 16 (IBD1) to ulcerative colitis

artículo científico publicado en 1998

Evidence that breast cancer risk at the 2q35 locus is mediated through IGFBP5 regulation

artículo científico publicado en 2014

Evidence that the 5p12 Variant rs10941679 Confers Susceptibility to Estrogen-Receptor-Positive Breast Cancer through FGF10 and MRPS30 Regulation

scientific article published on 03 September 2016

Exclusion of linkage of loci on chromosome 19 with multiple endocrine neoplasia, type 2

artículo científico publicado en 1987

Exome array analysis identifies ETFB as a novel susceptibility gene for anthracycline-induced cardiotoxicity in cancer patients

artículo científico publicado en 2017

Exome array analysis identifies GPR35 as a novel susceptibility gene for anthracycline-induced cardiotoxicity in childhood cancer

artículo científico publicado en 2017

Exploring the link between MORF4L1 and risk of breast cancer

artículo científico publicado en 2011

Exposure to diagnostic radiation and risk of breast cancer among carriers of BRCA1/2 mutations: retrospective cohort study (GENE-RAD-RISK).

artículo científico publicado en 2012

FGF receptor genes and breast cancer susceptibility: results from the Breast Cancer Association Consortium

artículo científico publicado en 2014

FGFR2 variants and breast cancer risk: fine-scale mapping using African American studies and analysis of chromatin conformation

artículo científico publicado en 2009

Familial cancer syndromes

artículo científico publicado en 1994

Familial cylindromatosis (turban tumour syndrome) gene localised to chromosome 16q12-q13: evidence for its role as a tumour suppressor gene

artículo científico publicado en 1995

Familial predisposition to breast cancer in a British population: implications for prevention

scientific article published on 01 April 2000

Familial prostate cancer: the evidence and the Cancer Research Campaign/British Prostate Group (CRC/BPG) UK Familial Prostate Cancer Study

artículo científico publicado en 1997

Familial relative risks for breast cancer by pathological subtype: a population-based cohort study

artículo científico publicado en 2010

Familial risks of breast cancer

artículo científico publicado en 2002

Familial site-specific ovarian cancer is linked to BRCA1 on 17q12-21.

artículo científico publicado en 1994

Family history and the risk of breast cancer: a systematic review and meta-analysis

artículo científico publicado en 1997

Family history of breast cancer: referral guidelines changed after acceptance of 10 minute consultation

artículo científico publicado en 2005

FastPop: a rapid principal component derived method to infer intercontinental ancestry using genetic data

artículo científico publicado en 2016

Fine scale mapping of the 17q22 breast cancer locus using dense SNPs, genotyped within the Collaborative Oncological Gene-Environment Study (COGs).

artículo científico publicado en 2016

Fine scale mapping of the breast cancer 16q12 locus

artículo científico publicado en 2010

Fine-Mapping of the 1p11.2 Breast Cancer Susceptibility Locus

artículo científico publicado en 2016

Fine-Scale Mapping at 9p22.2 Identifies Candidate Causal Variants That Modify Ovarian Cancer Risk in BRCA1 and BRCA2 Mutation Carriers

artículo científico publicado en 2016

Fine-mapping identifies multiple prostate cancer risk loci at 5p15, one of which associates with TERT expression

artículo científico publicado en 2013

Fine-mapping identifies multiple prostate cancer risk loci at 5p15, one of which associates with TERT expression.

artículo científico publicado en 2013

Fine-mapping identifies two additional breast cancer susceptibility loci at 9q31.2.

artículo científico publicado en 2015

Fine-mapping of 150 breast cancer risk regions identifies 178 high confidence target genes

article

Fine-mapping of 150 breast cancer risk regions identifies 191 likely target genes

artículo científico publicado en 2020

Fine-mapping of prostate cancer susceptibility loci in a large meta-analysis identifies candidate causal variants.

artículo científico publicado en 2018

Fine-mapping of the HNF1B multicancer locus identifies candidate variants that mediate endometrial cancer risk

artículo científico publicado en 2014

Fine-mapping the HOXB region detects common variants tagging a rare coding allele: evidence for synthetic association in prostate cancer

artículo científico publicado en 2014

Fine-scale mapping of 8q24 locus identifies multiple independent risk variants for breast cancer

artículo científico publicado en 2016

Fine-scale mapping of the 4q24 locus identifies two independent loci associated with breast cancer risk

artículo científico publicado en 2015

Fine-scale mapping of the 5q11.2 breast cancer locus reveals at least three independent risk variants regulating MAP3K1.

artículo científico publicado en 2014

Fine-scale mapping of the FGFR2 breast cancer risk locus: putative functional variants differentially bind FOXA1 and E2F1.

artículo científico publicado en 2013

Five endometrial cancer risk loci identified through genome-wide association analysis

artículo científico publicado en 2016

Five polymorphisms and breast cancer risk: results from the Breast Cancer Association Consortium

artículo científico publicado en 2009

Floating absolute risk: an alternative to relative risk in survival and case-control analysis avoiding an arbitrary reference group

artículo científico publicado en 1991

Frequency of familial melanoma and MLM2 gene.

artículo científico publicado en 1995

From association to cause: fine mapping of the TNRC9 gene region, a novel susceptibility locus identified in the first genome-wide association study for breast cancer.

artículo científico publicado en 2008

Functional annotation of the 2q35 breast cancer risk locus implicates a structural variant in influencing activity of a long-range enhancer element

artículo científico publicado en 2021

Functional complementation studies identify candidate genes and common genetic variants associated with ovarian cancer survival

artículo científico publicado en 2009

Functional complementation studies identify candidate genes and common genetic variants associated with ovarian cancer survival

article

Functional mechanisms underlying pleiotropic risk alleles at the 19p13.1 breast-ovarian cancer susceptibility locus

artículo científico publicado en 2016

Functional polymorphisms in the TERT promoter are associated with risk of serous epithelial ovarian and breast cancers

artículo científico publicado en 2011

Functional variants at the 11q13 risk locus for breast cancer regulate cyclin D1 expression through long-range enhancers

artículo científico publicado en 2013

GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer

artículo científico publicado en 2013

GWAS meta-analysis of 16 852 women identifies new susceptibility locus for endometrial cancer

artículo científico

Gene and pathway level analyses of germline DNA-repair gene variants and prostate cancer susceptibility using the iCOGS-genotyping array

artículo científico publicado en 2016

Gene and pathway level analyses of germline DNA-repair gene variants and prostate cancer susceptibility using the iCOGS-genotyping array

artículo científico publicado en 2018

Gene-environment interactions involving functional variants: Results from the Breast Cancer Association Consortium

artículo científico publicado en 2017

Gene-gene interactions in breast cancer susceptibility

artículo científico publicado en 2011

Gene-panel sequencing and the prediction of breast-cancer risk

artículo científico publicado en 2015

Generalizability of established prostate cancer risk variants in men of African ancestry

artículo científico publicado en 2014

Genetic Risk Score Mendelian Randomization Shows that Obesity Measured as Body Mass Index, but not Waist:Hip Ratio, Is Causal for Endometrial Cancer

artículo científico publicado en 2016

Genetic Variants Related to Longer Telomere Length are Associated with Increased Risk of Renal Cell Carcinoma

artículo científico publicado en 2017

Genetic analyses of gynecological disease identify genetic relationships between uterine fibroids and endometrial cancer, and a novel endometrial cancer genetic risk region at the WNT4 1p36.12 locus

artículo científico publicado en 2021

Genetic and Histopathologic Evaluation ofBRCA1andBRCA2DNA Sequence Variants of Unknown Clinical Significance

article

Genetic association of an LBP-1c/CP2/LSF gene polymorphism with late onset Alzheimer's disease

artículo científico publicado en 2001

Genetic evidence and integration of various data sources for classifying uncertain variants into a single model

artículo científico publicado en 2008

Genetic heterogeneity and localization of a familial breast-ovarian cancer gene on chromosome 17q12-q21

artículo científico publicado en 1993

Genetic heterogeneity and penetrance analysis of the BRCA1 and BRCA2 genes in breast cancer families. The Breast Cancer Linkage Consortium

artículo científico publicado en 1998

Genetic heterogeneity of breast-ovarian cancer revisited. Breast Cancer Linkage Consortium

artículo científico publicado en 1995

Genetic insights into biological mechanisms governing human ovarian ageing

artículo científico publicado en 2021

Genetic linkage analysis in familial breast and ovarian cancer: results from 214 families. The Breast Cancer Linkage Consortium

artículo científico publicado en 1993

Genetic linkage studies map the multiple endocrine neoplasia type 2 loci to a small interval on chromosome 10q11.2

artículo científico publicado en 1993

Genetic models for the familial aggregation of mammographic breast density

artículo científico publicado en 2009

Genetic modifiers of CHEK2*1100delC-associated breast cancer risk

scientific article published on 06 October 2016

Genetic modifiers of menopausal hormone replacement therapy and breast cancer risk: a genome-wide interaction study

artículo científico publicado en 2013

Genetic overlap between endometriosis and endometrial cancer: evidence from cross-disease genetic correlation and GWAS meta-analyses.

artículo científico publicado en 2018

Genetic predisposition to ductal carcinoma in situ of the breast

artículo científico publicado en 2016

Genetic predisposition to in situ and invasive lobular carcinoma of the breast

artículo científico publicado en 2014

Genetic predisposition to mosaic Y chromosome loss in blood

scientific article published on 20 November 2019

Genetic predisposition to mosaic Y chromosome loss in blood is associated with genomic instability in other tissues and susceptibility to non-haematological cancers

Genetic susceptibility to breast cancer

artículo científico publicado en 2010

Genetic susceptibility to naevi – a twin study

artículo científico publicado el 1 de diciembre de 1991

Genetic susceptibility to radiation-induced breast cancer after Hodgkin lymphoma

scholarly article by Annemieke W J Opstal-van Winden et al published 7 March 2019 in Blood

Genetic variant predictors of gene expression provide new insight into risk of colorectal cancer

article

Genetic variants associated with predisposition to prostate cancer and potential clinical implications

artículo científico publicado en 2012

Genetic variants in ER cofactor genes and endometrial cancer risk

artículo científico publicado en 2012

Genetic variants in epigenetic genes and breast cancer risk.

artículo científico publicado en 2006

Genetic variation at 9p22.2 and ovarian cancer risk for BRCA1 and BRCA2 mutation carriers

artículo científico publicado en 2010

Genetic variation at CYP3A is associated with age at menarche and breast cancer risk: a case-control study

artículo científico publicado en 2014

Genetic variation in TYMS in the one-carbon transfer pathway is associated with ovarian carcinoma types in the Ovarian Cancer Association Consortium

artículo científico publicado en 2010

Genetic variation in mitotic regulatory pathway genes is associated with breast tumor grade

artículo científico publicado en 2014

Genetic variation in prostate-specific antigen-detected prostate cancer and the effect of control selection on genetic association studies

scientific journal article

Genetic variation in stromal proteins decorin and lumican with breast cancer: investigations in two case-control studies

artículo científico publicado en 2008

Genetic variation in the chromosome 17q23 amplicon and breast cancer risk

scientific article published on 19 May 2009

Genetic variation in the immunosuppression pathway genes and breast cancer susceptibility: a pooled analysis of 42,510 cases and 40,577 controls from the Breast Cancer Association Consortium

artículo científico publicado en 2015

Genetically Predicted Body Mass Index and Breast Cancer Risk: Mendelian Randomization Analyses of Data from 145,000 Women of European Descent

artículo científico publicado en 2016

Genetically Predicted Levels of DNA Methylation Biomarkers and Breast Cancer Risk: Data From 228 951 Women of European Descent

scientific article published on 01 March 2020

Genome-Wide Meta-Analyses of Breast, Ovarian, and Prostate Cancer Association Studies Identify Multiple New Susceptibility Loci Shared by at Least Two Cancer Types

artículo científico publicado en 2016

Genome-wide association analysis identifies three new breast cancer susceptibility loci

artículo científico publicado en 2012

Genome-wide association analysis of more than 120,000 individuals identifies 15 new susceptibility loci for breast cancer

artículo científico publicado en 2015

Genome-wide association and transcriptome studies identify target genes and risk loci for breast cancer

article

Genome-wide association meta-analyses combining multiple risk phenotypes provide insights into the genetic architecture of cutaneous melanoma susceptibility

artículo científico publicado en 2020

Genome-wide association studies identify four ER negative-specific breast cancer risk loci

artículo científico publicado en 2013

Genome-wide association studies in cancer

artículo científico publicado en 2008

Genome-wide association studies in common cancers--what have we learnt?

scientific article published on 24 April 2010

Genome-wide association study for ovarian cancer susceptibility using pooled DNA.

artículo científico publicado en 2012

Genome-wide association study identifies 25 known breast cancer susceptibility loci as risk factors for triple-negative breast cancer

artículo científico publicado en 2013

Genome-wide association study identifies 32 novel breast cancer susceptibility loci from overall and subtype-specific analyses

scientific article published on 18 May 2020

Genome-wide association study identifies a common variant associated with risk of endometrial cancer

artículo científico publicado en 2011

Genome-wide association study identifies a common variant in RAD51B associated with male breast cancer risk

artículo científico publicado en 2012

Genome-wide association study identifies a possible susceptibility locus for endometrial cancer

artículo científico publicado en 2012

Genome-wide association study identifies five new breast cancer susceptibility loci

artículo científico publicado en 2010

Genome-wide association study identifies multiple loci associated with both mammographic density and breast cancer risk

artículo científico publicado en 2014

Genome-wide association study identifies multiple risk loci for renal cell carcinoma

artículo científico publicado en 2017

Genome-wide association study identifies new prostate cancer susceptibility loci

scientific journal article

Genome-wide association study identifies novel breast cancer susceptibility loci

artículo científico publicado en 2007

Genome-wide association study identifies susceptibility loci for B-cell childhood acute lymphoblastic leukemia

artículo científico publicado en 2018

Genome-wide association study identifies three new melanoma susceptibility loci

artículo científico publicado en 2011

Genome-wide association study implicates immune dysfunction in the development of Hodgkin lymphoma

artículo científico publicado en 2018

Genome-wide association study in BRCA1 mutation carriers identifies novel loci associated with breast and ovarian cancer risk

artículo científico publicado en 2013

Genome-wide association study of circulating estradiol, testosterone, and sex hormone-binding globulin in postmenopausal women

artículo científico publicado en 2012

Genome-wide association study of classical Hodgkin lymphoma identifies key regulators of disease susceptibility

artículo científico publicado en 2017

Genome-wide association study of endometrial cancer in E2C2

artículo científico publicado en 2014

Genome-wide association study of germline variants and breast cancer-specific mortality

artículo científico publicado en 2019

Genome-wide association study of prostate cancer-specific survival

artículo científico publicado en 2015

Genome-wide association study of renal cell carcinoma identifies two susceptibility loci on 2p21 and 11q13.3

scientific journal article

Genome-wide association study of subtype-specific epithelial ovarian cancer risk alleles using pooled DNA.

artículo científico publicado en 2013

Genome-wide association study of susceptibility loci for breast cancer in Sardinian population

artículo científico publicado en 2015

Genome-wide linkage analysis of 1,233 prostate cancer pedigrees from the International Consortium for Prostate Cancer Genetics using novel sumLINK and sumLOD analyses

artículo científico publicado en 2010

Genome-wide linkage disequilibrium mapping of late-onset Alzheimer’s disease in Finland

artículo científico publicado el 13 de noviembre de 2001

Genome-wide linkage screen for testicular germ cell tumour susceptibility loci

artículo científico publicado en 2006

Genome-wide meta-analysis identifies five new susceptibility loci for cutaneous malignant melanoma

artículo científico publicado en 2015

Genomic analyses for age at menarche identify 389 independent signals and indicate BMI-independent effects of puberty timing on cancer susceptibility

artículo científico publicado en 2016

Genomic analyses identify hundreds of variants associated with age at menarche and support a role for puberty timing in cancer risk

artículo científico publicado en 2017

Genomic analysis of male puberty timing highlights shared genetic basis with hair colour and lifespan

artículo científico publicado en 2020

Germline BRCA mutation and outcome in young-onset breast cancer (POSH): a prospective cohort study

artículo científico publicado en 2018

Germline BRCA mutations are associated with higher risk of nodal involvement, distant metastasis, and poor survival outcomes in prostate cancer

artículo científico publicado en 2013

Germline BRCA1 mutations increase prostate cancer risk

artículo científico publicado en 2012

Germline HOXB13 mutations p.G84E and p.R217C do not confer an increased breast cancer risk

artículo científico publicado en 2020

Germline determinants of the somatic mutation landscape in 2,642 cancer genomes

article

Germline mutation in BRCA1 or BRCA2 and ten-year survival for women diagnosed with epithelial ovarian cancer

artículo científico publicado en 2014

Germline mutations in fumarate hydratase (FH) do not predispose to prostate cancer

artículo científico publicado en 2003

Germline mutations of the BRCA1 gene in breast and ovarian cancer families provide evidence for a genotype–phenotype correlation

article

Germline variants and breast cancer survival in patients with distant metastases at primary breast cancer diagnosis

artículo científico publicado en 2021

Germline variation at 8q24 and prostate cancer risk in men of European ancestry

artículo científico publicado en 2018

HLA and inflammatory bowel disease

scientific article published on 01 July 1996

HOXB13 is a susceptibility gene for prostate cancer: results from the International Consortium for Prostate Cancer Genetics (ICPCG).

artículo científico publicado en 2012

HPC2/ELAC2 polymorphisms and prostate cancer risk: analysis by age of onset of disease

artículo científico publicado en 2002

Hand pattern indicates prostate cancer risk

artículo científico publicado en 2010

HapMap-based study of the 17q21 ERBB2 amplicon in susceptibility to breast cancer

artículo científico publicado en 2006

Haplotype and phenotype analysis of nine recurrent BRCA2 mutations in 111 families: results of an international study

artículo científico publicado en 1998

Haplotype and phenotype analysis of six recurrent BRCA1 mutations in 61 families: results of an international study

artículo científico publicado en 1996

Haplotype structure in Ashkenazi Jewish BRCA1 and BRCA2 mutation carriers

artículo científico publicado en 2011

Height and Body Mass Index as Modifiers of Breast Cancer Risk in BRCA1/2 Mutation Carriers: A Mendelian Randomization Study

artículo científico publicado en 2019

Height and Breast Cancer Risk: Evidence From Prospective Studies and Mendelian Randomization

artículo científico publicado en 2015

Height, selected genetic markers and prostate cancer risk: results from the PRACTICAL consortium

artículo científico publicado en 2017

Height, selected genetic markers and prostate cancer risk: results from the PRACTICAL consortium

article by Artitaya Lophatananon et al published 20 March 2018 in British Journal of Cancer

Heterogeneity of breast cancer associations with five susceptibility loci by clinical and pathological characteristics

artículo científico publicado en 2008

Heterogeneity of luminal breast cancer characterised by immunohistochemical expression of basal markers

artículo científico publicado en 2015

High prevalence of the 999del5 mutation in icelandic breast and ovarian cancer patients

scientific article published on 01 August 1996

High risk genes predisposing to prostate cancer development—do they exist?

High-throughput allelic expression imbalance analyses identify candidate breast cancer risk genes

scholarly article

High-throughput automated scoring of Ki67 in breast cancer tissue microarrays from the Breast Cancer Association Consortium

artículo científico publicado en 2016

How many more breast cancer predisposition genes are there?

artículo científico publicado en 1999

Human familial and sporadic breast cancer: analysis of the coding regions of the 17 beta-hydroxysteroid dehydrogenase 2 gene (EDH17B2) using a single-strand conformation polymorphism assay

artículo científico publicado en 1994

Hyaluronan-mediated motility receptor gene single nucleotide polymorphisms and risk of breast cancer

artículo científico publicado en 2008

IGF1 and IGFBP3 tagging polymorphisms are associated with circulating levels of IGF1, IGFBP3 and risk of breast cancer

article

Identification and characterization of novel associations in the CASP8/ALS2CR12 region on chromosome 2 with breast cancer risk

artículo científico publicado en 2014

Identification and molecular characterization of a new ovarian cancer susceptibility locus at 17q21.31.

artículo científico publicado en 2013

Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer

artículo científico publicado en 2017

Identification of 19 new risk loci and potential regulatory mechanisms influencing susceptibility to testicular germ cell tumor

artículo científico publicado en 2017

Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array

artículo científico publicado en 2013

Identification of 31 loci for mammographic density phenotypes and their associations with breast cancer risk

artículo científico publicado en 2020

Identification of Women at High Risk of Breast Cancer Who Need Supplemental Screening

artículo científico publicado en 2020

Identification of a BRCA2-specific modifier locus at 6p24 related to breast cancer risk

artículo científico publicado en 2013

Identification of a novel percent mammographic density locus at 12q24.

artículo científico publicado en 2012

Identification of a novel prostate cancer susceptibility variant in the KLK3 gene transcript

artículo científico publicado en 2011

Identification of common variants in the SHBG gene affecting sex hormone-binding globulin levels and breast cancer risk in postmenopausal women

artículo científico publicado en 2008

Identification of four new susceptibility loci for testicular germ cell tumour

artículo científico publicado en 2015

Identification of four novel susceptibility loci for oestrogen receptor negative breast cancer

artículo científico publicado en 2016

Identification of independent association signals and putative functional variants for breast cancer risk through fine-scale mapping of the 12p11 locus

artículo científico publicado en 2016

Identification of multiple risk loci and regulatory mechanisms influencing susceptibility to multiple myeloma

scientific article published in Nature Communications

Identification of new genetic risk factors for prostate cancer

artículo científico publicado en 2008

Identification of new genetic susceptibility loci for breast cancer through consideration of gene-environment interactions

artículo científico publicado en 2013

Identification of nine new susceptibility loci for endometrial cancer

artículo científico publicado en 2018

Identification of nine new susceptibility loci for testicular cancer, including variants near DAZL and PRDM14

artículo científico publicado en 2013

Identification of novel breast cancer susceptibility loci in meta-analyses conducted among Asian and European descendants

artículo científico publicado en 2020

Identification of novel genetic markers of breast cancer survival

artículo científico publicado en 2015

Identification of seven new prostate cancer susceptibility loci through a genome-wide association study

artículo científico publicado en 2009

Identification of shared and unique susceptibility pathways among cancers of the lung, breast, and prostate from genome-wide association studies and tissue-specific protein interactions

artículo científico publicado en 2015

Identification of six new susceptibility loci for invasive epithelial ovarian cancer

artículo científico publicado en 2015

Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer

artículo científico publicado en 2017

Immunocytochemical determination of estrogen receptor, progesterone receptor, and 1,25-dihydroxyvitamin D3 receptor in breast cancer and relationship to prognosis

artículo científico publicado el 1 de enero de 1991

Implications of polygenic risk-stratified screening for prostate cancer on overdiagnosis

artículo científico publicado en 2015

Incorporating Functional Genomic Information in Genetic Association Studies Using an Empirical Bayes Approach

artículo científico publicado en 2016

Incorporating progesterone receptor expression into the PREDICT breast prognostic model

artículo científico publicado en 2022

Incorporating truncating variants in PALB2, CHEK2, and ATM into the BOADICEA breast cancer risk model

artículo científico publicado en 2016

Incorporating tumour pathology information into breast cancer risk prediction algorithms

artículo científico publicado en 2010

Influence of cytokine gene polymorphisms on the development of prostate cancer

article

Inheritance of deleterious mutations at both BRCA1 and BRCA2 in an international sample of 32,295 women

artículo científico publicado en 2016

Inherited genetic susceptibility to breast cancer: the beginning of the end or the end of the beginning?

artículo científico publicado en 2013

Inherited mutations in BRCA1 and BRCA2 in an unselected multiethnic cohort of Asian patients with breast cancer and healthy controls from Malaysia

artículo científico publicado en 2017

Inherited susceptibility to breast cancer

artículo científico publicado en 1993

Inherited variants in the inner centromere protein (INCENP) gene of the chromosomal passenger complex contribute to the susceptibility of ER-negative breast cancer

artículo científico publicado en 2015

Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease

artículo científico publicado en 2004

Integrated evaluation of DNA sequence variants of unknown clinical significance: application to BRCA1 and BRCA2

artículo científico publicado en 2004

Integration of multiethnic fine-mapping and genomic annotation to prioritize candidate functional SNPs at prostate cancer susceptibility regions

artículo científico publicado en 2015

Interactions between genes involved in the antioxidant defence system and breast cancer risk

artículo científico publicado en 2006

Interim analysis of the incidence of breast cancer in the Royal Marsden Hospital tamoxifen randomised chemoprevention trial

artículo científico publicado en 1998

International network of cancer genome projects

artículo científico publicado en 2010

Interplay between BRCA1 and RHAMM regulates epithelial apicobasal polarization and may influence risk of breast cancer

artículo científico publicado en 2011

Investigating the possible causal role of coffee consumption with prostate cancer risk and progression using Mendelian randomization analysis

artículo científico publicado en 2016

Investigation of gene-environment interactions between 47 newly identified breast cancer susceptibility loci and environmental risk factors

artículo científico publicado en 2014

Is Schizophrenia a Risk Factor for Breast Cancer?—Evidence From Genetic Data

artículo científico publicado en 2019

Is the genetics of moliness simply the genetics of sun exposure? A path analysis of nevus counts and risk factors in British twins

artículo científico publicado en 1992

Joint association of mammographic density adjusted for age and body mass index and polygenic risk score with breast cancer risk

article

Joint associations of a polygenic risk score and environmental risk factors for breast cancer in the Breast Cancer Association Consortium

artículo científico publicado en 2018

Large-Scale Genomic Analyses Link Reproductive Aging to Hypothalamic Signaling, Breast Cancer Susceptibility, and BRCA1-Mediated DNA Repair

artículo científico publicado en 2015

Large-scale Analysis Demonstrates Familial Testicular Cancer to have Polygenic Aetiology

artículo científico publicado en 2018

Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair

artículo científico publicado en 2015

Large-scale genotyping identifies 41 new loci associated with breast cancer risk

artículo científico publicado en 2013

Late toxicity is not increased in BRCA1/BRCA2 mutation carriers undergoing breast radiotherapy in the United Kingdom

artículo científico publicado en 2006

Letter to the editor: a response to Ming's study on machine learning techniques for personalized breast cancer risk prediction

scientific article published on 10 February 2020

Life stress, emotional health, and mean telomere length in the European Prospective Investigation into Cancer (EPIC)-Norfolk population study

artículo científico publicado en 2011

Lifetime risks of common cancers among retinoblastoma survivors

artículo científico publicado en 2004

Linkage analysis and genetic models for IDDM.

artículo científico publicado en 1989

Linkage analysis in non-Mendelian disorders

scientific article published on 01 January 1989

Linkage analysis of 56 multiplex families excludes the Cowden disease gene PTEN as a major contributor to familial breast cancer.

artículo científico publicado en 1999

Linkage analysis of British and Indian families with Von Recklinghausen neurofibromatosis

artículo científico publicado en 1987

Linkage analysis of chromosome 17 markers in British and South African families with neurofibromatosis type I.

artículo científico publicado en 1989

Linkage analysis of chromosome 1q markers in 136 prostate cancer families. The Cancer Research Campaign/British Prostate Group U.K. Familial Prostate Cancer Study Collaborators

artículo científico publicado en 1998

Linkage of a nasopharyngeal carcinoma susceptibility locus to the HLA regions

artículo científico publicado en 1990

Linked markers flanking the gene for multiple endocrine neoplasia type 2A.

artículo científico publicado en 1989

Localisation of susceptibility genes for familial testicular germ cell tumour

artículo científico publicado en 2003

Localisation of the breast-ovarian cancer susceptibility gene (BRCAI) on 17q12–21 to an interval of IcM

article

Localization of the gene for Cowden disease to chromosome 10q22–23

article

Localization to Xq27 of a susceptibility gene for testicular germ-cell tumours

artículo científico publicado en 2000

Low penetrance breast cancer susceptibility loci are associated with specific breast tumor subtypes: findings from the Breast Cancer Association Consortium

artículo científico publicado en 2011

Low-dose ionizing radiation significantly increases the risk of breast cancer among BRCA1/2 mutation carriers in the International BRCA1/2 Carrier Cohort Study (IBCCS).

artículo científico publicado en 2005

Low-penetrance susceptibility to breast cancer due to CHEK2(*)1100delC in noncarriers of BRCA1 or BRCA2 mutations

artículo científico publicado en 2002

Lymphocyte telomere length is long in BRCA1 and BRCA2 mutation carriers regardless of cancer-affected status

artículo científico publicado en 2014

Lymphoid tumours and breast cancer in ataxia telangiectasia; substantial protective effect of residual ATM kinase activity against childhood tumours

artículo científico publicado el 26 de julio de 2011

MEDULLOBLASTOMA

Macrophage scavenger receptor 1 999C>T (R293X) mutation and risk of prostate cancer

artículo científico publicado en 2005

Magnetic resonance imaging screening in women at genetic risk of breast cancer: imaging and analysis protocol for the UK multicentre study. UK MRI Breast Screening Study Advisory Group

artículo científico publicado en 2000

Male breast cancer in BRCA1 and BRCA2 mutation carriers: pathology data from the Consortium of Investigators of Modifiers of BRCA1/2.

artículo científico publicado en 2016

Mammographic breast density and breast cancer: evidence of a shared genetic basis

artículo científico publicado en 2012

Mammographic density and breast cancer risk in BRCA1 and BRCA2 mutation carriers

artículo científico publicado en 2006

Mammographic density, estrogen receptor status and other breast cancer tumor characteristics

artículo científico publicado en 2010

Measurement of 1,25-dihydroxyvitamin D3 receptors in breast cancer and their relationship to biochemical and clinical indices

artículo científico publicado el 1 de abril de 1984

Mendelian randomisation study of height and body mass index as modifiers of ovarian cancer risk in 22,588 BRCA1 and BRCA2 mutation carriers

scientific article published on 19 June 2019

Mendelian randomisation study of smoking exposure in relation to breast cancer risk

artículo científico publicado en 2021

Mendelian randomization analyses suggest a role for cholesterol in the development of endometrial cancer

artículo científico publicado en 2020

Mendelian randomization analysis of C-reactive protein on colorectal cancer risk

scientific article published on 01 June 2019

Mendelian randomization study of adiposity-related traits and risk of breast, ovarian, prostate, lung and colorectal cancer.

artículo científico publicado en 2016

Meta-analysis of genome-wide association studies identifies common susceptibility polymorphisms for colorectal and endometrial cancer near SH2B3 and TSHZ1.

artículo científico publicado en 2015

Meta-analysis of up to 622,409 individuals identifies 40 novel smoking behaviour associated genetic loci

artículo científico publicado en 2019

MicroRNA related polymorphisms and breast cancer risk

artículo científico publicado en 2014

Micrometastases in bone marrow in patients with primary breast cancer: evaluation as an early predictor of bone metastases

artículo científico publicado en 1987

Mismatch repair gene polymorphisms and survival in invasive ovarian cancer patients

artículo científico publicado en 2008

Missense variants in ATM in 26,101 breast cancer cases and 29,842 controls

artículo científico publicado en 2010

Models for respiratory cancer in nickel refinery workers

artículo científico

Models for skin tumour risks in workers exposed to mineral oils

artículo científico publicado en 1990

Models of genetic susceptibility to breast cancer

artículo científico publicado en 2006

Modification of BRCA1-Associated Breast and Ovarian Cancer Risk by BRCA1-Interacting Genes

artículo científico publicado en 2011

More on Co-Occurrence of COMT and BRCA1/2 Variants in a Population

artículo científico publicado en 2017

Mortality from respiratory cancer and other causes in United Kingdom chromate production workers

artículo científico publicado en 1991

Most common 'sporadic' cancers have a significant germline genetic component

artículo científico publicado en 2014

Multi-stage genome-wide association study identifies new susceptibility locus for testicular germ cell tumour on chromosome 3q25

artículo científico publicado en 2014

Multifactorial analysis of differences between sporadic breast cancers and cancers involving BRCA1 and BRCA2 mutations

artículo científico publicado en 1998

Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer

artículo científico publicado en 2013

Multiple loci on 8q24 associated with prostate cancer susceptibility

artículo científico publicado en 2009

Multiple loci with different cancer specificities within the 8q24 gene desert

artículo científico publicado en 2008

Multiple newly identified loci associated with prostate cancer susceptibility

artículo científico publicado en 2008

Multiple novel prostate cancer predisposition loci confirmed by an international study: the PRACTICAL Consortium

artículo científico publicado en 2008

Multiple novel prostate cancer susceptibility signals identified by fine-mapping of known risk loci among Europeans

artículo científico publicado en 2015

Mutation analysis of the MSMB gene in familial prostate cancer

artículo científico publicado en 2009

Mutational Spectrum in a Worldwide Study of 29,700 Families with BRCA1 or BRCA2 Mutations

artículo científico publicado en 2018

Mutations in CUL4B, which encodes a ubiquitin E3 ligase subunit, cause an X-linked mental retardation syndrome associated with aggressive outbursts, seizures, relative macrocephaly, central obesity, hypogonadism, pes cavus, and tremor

artículo científico publicado en 2007

Mutations in ZDHHC9, which encodes a palmitoyltransferase of NRAS and HRAS, cause X-linked mental retardation associated with a Marfanoid habitus

artículo científico publicado en 2007

Mutations in the DLG3 gene cause nonsyndromic X-linked mental retardation

artículo científico publicado en 2004

Mutations in the gene encoding the Sigma 2 subunit of the adaptor protein 1 complex, AP1S2, cause X-linked mental retardation

artículo científico publicado en 2006

National Cancer Institute Prostate Cancer Genetics Workshop

artículo científico publicado en 2011

Network-Based Integration of GWAS and Gene Expression Identifies a HOX-Centric Network Associated with Serous Ovarian Cancer Risk

artículo científico publicado en 2015

Newly discovered breast cancer susceptibility loci on 3p24 and 17q23.2.

artículo científico publicado en 2009

No association between FTO or HHEX and endometrial cancer risk

artículo científico publicado en 2010

No association between TERT-CLPTM1L single nucleotide polymorphism rs401681 and mean telomere length or cancer risk

artículo científico publicado en 2010

No association between a polymorphism in the steroid metabolism gene CYP17 and risk of breast cancer

artículo científico publicado el 1 de junio de 1998

No association between androgen or vitamin D receptor gene polymorphisms and risk of breast cancer

artículo científico publicado en 1999

No association of TGFB1 L10P genotypes and breast cancer risk in BRCA1 and BRCA2 mutation carriers: a multi-center cohort study

artículo científico publicado en 2008

No clinical utility of KRAS variant rs61764370 for ovarian or breast cancer.

artículo científico publicado en 2015

No evidence for an association between Saitohin Q7R polymorphism and Alzheimer's disease

artículo científico publicado en 2002

No evidence for germline mutations in exons 5-9 of the p53 gene in 25 breast cancer families

artículo científico publicado en 1992

No evidence of germline PTEN mutations in familial prostate cancer

artículo científico publicado en 2000

No evidence that CDKN1B (p27) polymorphisms modify breast cancer risk in BRCA1 and BRCA2 mutation carriers

artículo científico publicado en 2008

No evidence that GATA3 rs570613 SNP modifies breast cancer risk

scientific article published on 11 December 2008

No evidence that protein truncating variants in BRIP1 are associated with breast cancer risk: implications for gene panel testing

scientific article published on 26 February 2016

No germline mutations in the dimerization domain of MXI1 in prostate cancer clusters. The CRC/BPG UK Familial Prostate Cancer Study Collaborators. Cancer Research Campaign/British Prostate Group

artículo científico publicado en 1997

Non-coding RNAs underlie genetic predisposition to breast cancer

artículo científico publicado en 2020

Novel Associations between Common Breast Cancer Susceptibility Variants and Risk-Predicting Mammographic Density Measures

artículo científico publicado en 2015

Novel Common Genetic Susceptibility Loci for Colorectal Cancer

artículo científico publicado en 2019

Novel bayes factors that capture expert uncertainty in prior density specification in genetic association studies

artículo científico publicado en 2015

Optimal strategies for mapping complex diseases in the presence of multiple loci

artículo científico publicado en 1997

Oral Contraceptive Use and Breast Cancer Risk: Retrospective and Prospective Analyses From a BRCA1 and BRCA2 Mutation Carrier Cohort Study

artículo científico publicado en 2018

Oral contraceptives and breast cancer risk in the International BRCA1/2 Carrier Cohort Study (IBCCS)

Oral contraceptives and breast cancer risk in the international BRCA1/2 carrier cohort study: a report from EMBRACE, GENEPSO, GEO-HEBON, and the IBCCS Collaborating Group

artículo científico publicado en 2007

Ovarian and breast cancer risks associated with pathogenic variants in RAD51C and RAD51D

artículo científico publicado en 2020

Ovarian and breast cancer risks to women in families with two or more cases of ovarian cancer

artículo científico publicado en 2000

Ovarian cancer familial relative risks by tumour subtypes and by known ovarian cancer genetic susceptibility variants

artículo científico publicado en 2013

Ovarian cancer risk in BRCA1 carriers is modified by the HRAS1 variable number of tandem repeat (VNTR) locus

artículo científico publicado en 1996

Ovarian cancer susceptibility alleles and risk of ovarian cancer in BRCA1 and BRCA2 mutation carriers

artículo científico publicado en 2012

Overexpression of RAD51 occurs in aggressive prostatic cancer

artículo científico publicado en 2009

PALB2, CHEK2 and ATM rare variants and cancer risk: data from COGS

artículo científico publicado en 2016

PALB2, which encodes a BRCA2-interacting protein, is a breast cancer susceptibility gene

artículo científico publicado en 2007

PHIP - a novel candidate breast cancer susceptibility locus on 6q14.1.

artículo científico publicado en 2017

PROTEIN-CODING VARIANTS IMPLICATE NOVEL GENES RELATED TO LIPID HOMEOSTASIS CONTRIBUTING TO BODY FAT DISTRIBUTION

article

Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche

artículo científico publicado en 2014

Parity and breast cancer risk among BRCA1 and BRCA2 mutation carriers

artículo científico publicado en 2006

Partnering in oncogenetic research--the INHERIT BRCAs experience: opportunities and challenges

artículo científico publicado en 2006

Pathology of Tumors Associated With Pathogenic Germline Variants in 9 Breast Cancer Susceptibility Genes

artículo científico publicado en 2022

Pathology of breast and ovarian cancers among BRCA1 and BRCA2 mutation carriers: results from the Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA)

artículo científico publicado en 2011

Pathology of ovarian cancers in BRCA1 and BRCA2 carriers

artículo científico publicado en 2004

Patient survival and tumor characteristics associated with CHEK2:p.I157T - findings from the Breast Cancer Association Consortium

artículo científico publicado en 2016

Patterns of somatic mutation in human cancer genomes

artículo científico publicado en 2007

Performance of automated scoring of ER, PR, HER2, CK5/6 and EGFR in breast cancer tissue microarrays in the Breast Cancer Association Consortium

artículo científico publicado en 2014

Personalized early detection and prevention of breast cancer: ENVISION consensus statement

scientific article published on 18 June 2020

Personalizing Breast Cancer Screening Based on Polygenic Risk and Family History

artículo científico publicado en 2020

Physical activity and mammographic breast density in the EPIC-Norfolk cohort study

artículo científico publicado en 2007

Polygenes, risk prediction, and targeted prevention of breast cancer

artículo científico publicado en 2008

Polygenic Inherited Predisposition to Breast Cancer

article published in 2005

Polygenic Risk Scores for Prediction of Breast Cancer and Breast Cancer Subtypes

artículo científico publicado en 2019

Polygenic hazard score to guide screening for aggressive prostate cancer: development and validation in large scale cohorts

artículo científico publicado en 2018

Polygenic inheritance of breast cancer: Implications for design of association studies

artículo científico publicado el 1 de noviembre de 2003

Polygenic risk score is associated with increased disease risk in 52 Finnish breast cancer families

scientific article published on 20 July 2016

Polygenic risk scores and breast and epithelial ovarian cancer risks for carriers of BRCA1 and BRCA2 pathogenic variants

artículo científico publicado en 2020

Polygenic susceptibility to breast cancer and implications for prevention

artículo científico publicado en 2002

Polygenic susceptibility to prostate and breast cancer: implications for personalised screening

artículo científico publicado en 2011

Polyglutamine repeat length in theAIB1 gene modifies breast cancer susceptibility inBRCA1 carriers

article

Polymorphism in the IL18 gene and epithelial ovarian cancer in non-Hispanic white women

artículo científico publicado en 2008

Polymorphisms associated with circulating sex hormone levels in postmenopausal women

artículo científico publicado en 2004

Polymorphisms in CYP1A1 and smoking: no association with breast cancer risk

artículo científico publicado en 2001

Polymorphisms in DNA repair genes and epithelial ovarian cancer risk

article

Polymorphisms in a Putative Enhancer at the 10q21.2 Breast Cancer Risk Locus Regulate NRBF2 Expression

artículo científico publicado en 2015

Polymorphisms in inflammation pathway genes and endometrial cancer risk

artículo científico publicado en 2012

Polymorphisms in the human aromatase cytochrome P450 gene (CYP19) and breast cancer risk

artículo científico publicado en 2000

Polymorphisms of an innate immune gene, toll-like receptor 4, and aggressive prostate cancer risk: a systematic review and meta-analysis.

artículo científico publicado en 2014

Polyunsaturated fatty acids and prostate cancer risk: a Mendelian randomisation analysis from the PRACTICAL consortium

artículo científico publicado en 2016

Pooled analysis indicates that the GSTT1 deletion, GSTM1 deletion, and GSTP1 Ile105Val polymorphisms do not modify breast cancer risk in BRCA1 and BRCA2 mutation carriers

artículo científico publicado en 2009

Pooled genome linkage scan of aggressive prostate cancer: results from the International Consortium for Prostate Cancer Genetics

artículo científico publicado en 2006

Population-based estimate of the average age-specific cumulative risk of breast cancer for a defined set of protein-truncating mutations in BRCA1 and BRCA2. Australian Breast Cancer Family Study

artículo científico publicado en 1999

Population-based family studies in genetic epidemiology

artículo científico publicado en 2005

Predicting the likelihood of carrying a BRCA1 or BRCA2 mutation: validation of BOADICEA, BRCAPRO, IBIS, Myriad and the Manchester scoring system using data from UK genetics clinics

artículo científico publicado en 2008

Prediction and clinical utility of a contralateral breast cancer risk model

scientific article published on 17 December 2019

Prediction of BRCA1 status in patients with breast cancer using estrogen receptor and basal phenotype

artículo científico publicado en 2005

Prediction of Breast and Prostate Cancer Risks in Male BRCA1 and BRCA2 Mutation Carriers Using Polygenic Risk Scores

artículo científico publicado en 2017

Prediction of breast cancer risk based on common genetic variants in women of East Asian ancestry

artículo científico publicado en 2016

Prediction of breast cancer risk based on profiling with common genetic variants

artículo científico publicado en 2015

Prediction of contralateral breast cancer: external validation of risk calculators in 20 international cohorts

scientific article published on 11 April 2020

Prediction of individual genetic risk to prostate cancer using a polygenic score

artículo científico publicado en 2015

Preface to the breast cancer linkage consortium papers.

artículo científico publicado en 1993

Pregnancies, breast-feeding, and breast cancer risk in the International BRCA1/2 Carrier Cohort Study (IBCCS)

artículo científico publicado en 2006

Presurgical determination of estrogen receptor status using immunocytochemically stained fine needle aspirate smears in patients with breast cancer

scientific article published on 01 November 1987

Presymptomatic screening for multiple endocrine neoplasia type 2A with linked DNA markers. The MEN 2A International Collaborative Group

artículo científico publicado en 1991

Prevalence of BRCA1 and BRCA2 gene mutations in patients with early-onset breast cancer

scientific article published on 01 June 1999

Prevalence of BRCA1 and BRCA2 pathogenic variants in a large, unselected breast cancer cohort

Prognosis following chemotherapy for metastatic malignant teratoma

artículo científico publicado en 1987

Prognostic factors in non-infiltrating carcinoma of the bladder: a preliminary report

scientific article published on 01 December 1982

Prognostic factors in stage I non-seminomatous germ-cell testicular tumors managed by orchiectomy and surveillance: implications for adjuvant chemotherapy

scientific article published on 01 July 1986

Prognostic value of automated KI67 scoring in breast cancer: a centralised evaluation of 8088 patients from 10 study groups

artículo científico publicado en 2016

Prophylactic oophorectomy in inherited breast/ovarian cancer families

artículo científico publicado en 1995

Prostate Cancer Risk by BRCA2 Genomic Regions

artículo científico publicado en 2020

Prostate Cancer Risks for Male BRCA1 and BRCA2 Mutation Carriers: A Prospective Cohort Study

scientific article published on 06 September 2019

Prostate cancer in BRCA2 germline mutation carriers is associated with poorer prognosis.

artículo científico publicado en 2010

Prostate cancer in male BRCA1 and BRCA2 mutation carriers has a more aggressive phenotype

artículo científico publicado en 2008

Prostate cancer risk regions at 8q24 and 17q24 are differentially associated with somatic TMPRSS2:ERG fusion status

artículo científico publicado en 2016

Prostate cancer segregation analyses using 4390 families from UK and Australian population-based studies

article

Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

artículo científico publicado en 2017

Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution

article

Protocol for a national multi-centre study of magnetic resonance imaging screening in women at genetic risk of breast cancer

artículo científico publicado en 2000

Pubertal development and prostate cancer risk: Mendelian randomization study in a population-based cohort

artículo científico publicado en 2016

Publisher Correction: Evidence that breast cancer risk at the 2q35 locus is mediated through IGFBP5 regulation.

artículo científico publicado en 2018

Publisher Correction: Personalized early detection and prevention of breast cancer: ENVISION consensus statement

scientific article published on 29 June 2020

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

artículo científico publicado en 2018

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

artículo científico publicado en 2018

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

artículo científico publicado en 2019

Publisher Correction: Shared heritability and functional enrichment across six solid cancers

scientific article published on 23 September 2019

Quantifying the Genetic Correlation between Multiple Cancer Types

artículo científico

RAD51 135G-->C modifies breast cancer risk among BRCA2 mutation carriers: results from a combined analysis of 19 studies

artículo científico publicado en 2007

RAD51B in Familial Breast Cancer

artículo científico publicado en 2016

RESPONSE: Re: Polymorphisms Associated With Circulating Sex Hormone Levels in Postmenopausal Women

Radiogenomics: radiobiology enters the era of big data and team science

artículo científico publicado en 2014

Rare and low-frequency coding variants alter human adult height

artículo científico publicado en 2017

Rare coding variants and X-linked loci associated with age at menarche

artículo científico publicado en 2015

Rare germline copy number deletions of likely functional importance are implicated in endometrial cancer predisposition

artículo científico publicado en 2014

Rare germline copy number variants (CNVs) and breast cancer risk

artículo científico publicado en 2022

Rare, protein-truncating variants in ATM, CHEK2 and PALB2, but not XRCC2, are associated with increased breast cancer risks

artículo científico publicado en 2017

Rat Mcs5a is a compound quantitative trait locus with orthologous human loci that associate with breast cancer risk

artículo científico publicado en 2007

Rationale for a national multi-centre study of magnetic resonance imaging screening in women at genetic risk of breast cancer

artículo científico publicado en 2000

Re-evaluating genetic variants identified in candidate gene studies of breast cancer risk using data from nearly 280,000 women of Asian and European ancestry

scientific article published on 16 October 2019

Re: "Presenting statistical uncertainty in trends and dose-response relations"

artículo científico publicado en 2000

Re: On the use of familial aggregation in population-based case probands for calculating penetrance

artículo científico publicado en 2003

Reading protocol for dynamic contrast-enhanced MR images of the breast: sensitivity and specificity analysis

artículo científico publicado en 2005

Reducing GWAS Complexity

artículo científico publicado en 2016

Refined histopathological predictors of BRCA1 and BRCA2 mutation status: a large-scale analysis of breast cancer characteristics from the BCAC, CIMBA, and ENIGMA consortia

artículo científico publicado en 2014

Regional localization of polymorphic markers on chromosome 10 by physical and genetic mapping

artículo científico publicado en 1990

Relationship between glutathione S-transferase M1, P1 and T1 polymorphisms and early onset prostate cancer

artículo científico publicado en 2001

Repair in the mouse lung during low dose-rate irradiation

artículo científico publicado en 1986

Reply: Remarks on the BOADICEA model of genetic susceptibility to breast and ovarian Cancer Research UK

artículo científico publicado en 2005

Reply: ‘Hand pattern indicates risk of prostate cancer’

article by A A Rahman et al published July 2011 in British Journal of Cancer

Reproductive and hormonal factors, and ovarian cancer risk for BRCA1 and BRCA2 mutation carriers: results from the International BRCA1/2 Carrier Cohort Study

artículo científico publicado en 2009

Reproductive profiles and risk of breast cancer subtypes: a multi-center case-only study.

artículo científico publicado en 2017

Response of nitrosomethylurea-induced rat mammary tumor to endocrine therapy and comparison with clinical response

artículo científico publicado en 1986

Response to aminoglutethimide and cortisone acetate in advanced prostatic cancer

artículo científico publicado el 1 de diciembre de 1984

Results of a genome-wide linkage analysis in prostate cancer families ascertained through the ACTANE consortium.

artículo científico publicado en 2003

Risk Analysis of Prostate Cancer in PRACTICAL Consortium--Response

artículo científico publicado en 2016

Risk Analysis of Prostate Cancer in PRACTICAL, a Multinational Consortium, Using 25 Known Prostate Cancer Susceptibility Loci

artículo científico publicado en 2015

Risk estimation and screening in families of patients with medullary thyroid carcinoma

artículo científico publicado en 1988

Risk factors and clinical data related to oestrogen receptor status in women presenting with breast cancer

artículo científico publicado en 1985

Risk factors for the incidence of breast cancer: do they affect survival from the disease?

artículo científico publicado en 2008

Risk models for familial ovarian and breast cancer

artículo científico publicado en 2000

Risk of estrogen receptor-positive and -negative breast cancer and single-nucleotide polymorphism 2q35-rs13387042.

artículo científico publicado en 2009

Risk prediction models for familial breast cancer

artículo científico publicado en 2006

Risk-reducing salpingo-oophorectomy, natural menopause, and breast cancer risk: an international prospective cohort of BRCA1 and BRCA2 mutation carriers

scientific article published on 16 January 2020

Risks of Breast, Ovarian, and Contralateral Breast Cancer for BRCA1 and BRCA2 Mutation Carriers

artículo científico publicado en 2017

Risks of breast or ovarian cancer in BRCA1 or BRCA2 predictive test negatives: findings from the EMBRACE study

artículo científico publicado en 2018

Risks of cancer in BRCA1-mutation carriers. Breast Cancer Linkage Consortium

artículo científico publicado en 1994

Role of CHEK2*1100delC in unselected series of non-BRCA1/2 male breast cancers

artículo científico publicado en 2004

Role of MC1R variants in uveal melanoma

artículo científico publicado en 2003

Runs of homozygosity and testicular cancer risk

scientific article published on 01 July 2019

SNP interaction pattern identifier (SIPI): an intensive search for SNP-SNP interaction patterns

artículo científico publicado en 2017

SNP-SNP interaction analysis of NF-κB signaling pathway on breast cancer survival

artículo científico publicado en 2015

SNPs in the kallikrein gene region associated with prostate cancer risk: true cause or association by design?

artículo científico publicado en 2008

STK15 polymorphisms and association with risk of invasive ovarian cancer.

artículo científico publicado en 2004

Sampling distribution of summary linkage disequilibrium measures

artículo científico publicado en 2002

Screening for prostate cancer: the way ahead

artículo científico publicado en 2010

Screening for theBRCA1-ins6kbEx13mutation: potential for misdiagnosis

Screening with magnetic resonance imaging and mammography of a UK population at high familial risk of breast cancer: a prospective multicentre cohort study (MARIBS).

artículo científico publicado en 2005

Seq4SNPs: new software for retrieval of multiple, accurately annotated DNA sequences, ready formatted for SNP assay design

artículo científico publicado en 2009

Sequence variant classification and reporting: recommendations for improving the interpretation of cancer susceptibility genetic test results

artículo científico publicado en 2008

Sequencing of prostate cancers identifies new cancer genes, routes of progression and drug targets

artículo científico publicado en 2018

Seven prostate cancer susceptibility loci identified by a multi-stage genome-wide association study

artículo científico publicado en 2011

Sex specific associations in genome wide association analysis of renal cell carcinoma

scientific article published on 23 June 2019

Sexual activity and prostate cancer risk in men diagnosed at a younger age

artículo científico publicado en 2009

Shared heritability and functional enrichment across six solid cancers

artículo científico publicado en 2019

Shared heritability and functional enrichment across six solid cancers

Single nucleotide polymorphisms in the TP53 region and susceptibility to invasive epithelial ovarian cancer

artículo científico publicado en 2009

Single-nucleotide polymorphisms in the RB1 gene and association with breast cancer in the British population

artículo científico publicado en 2006

Somatic KIT mutations occur predominantly in seminoma germ cell tumors and are not predictive of bilateral disease: report of 220 tumors and review of literature

artículo científico publicado en 2008

Somatic mutations of KIT in familial testicular germ cell tumours

artículo científico publicado en 2004

Somatic mutations of the protein kinase gene family in human lung cancer

artículo científico publicado en 2005

Specific morphological features predictive for the basal phenotype in grade 3 invasive ductal carcinoma of breast

artículo científico publicado en 2006

Statistical analysis of pathogenicity of somatic mutations in cancer

artículo científico publicado en 2006

Subtyping of breast cancer by immunohistochemistry to investigate a relationship between subtype and short and long term survival: a collaborative analysis of data for 10,159 cases from 12 studies

artículo científico publicado en 2010

Suggestive evidence for a site specific prostate cancer gene on chromosome 1p36. The CRC/BPG UK Familial Prostate Cancer Study Coordinators and Collaborators. The EU Biomed Collaborators

artículo científico publicado en 2000

Survival in familial, BRCA1-associated, and BRCA2-associated epithelial ovarian cancer. United Kingdom Coordinating Committee for Cancer Research (UKCCCR) Familial Ovarian Cancer Study Group

scientific article published on 01 February 1999

Survival of patients with breast cancer attending Bristol Cancer Help Centre

artículo científico publicado en 1990

Systematic Population-Based Assessment of Cancer Risk in First-Degree Relatives of Cancer Probands

artículo científico publicado en 1994

TGF-β signaling pathway and breast cancer susceptibility

artículo científico publicado en 2011

TP53-based interaction analysis identifies cis-eQTL variants for TP53BP2, FBXO28, and FAM53A that associate with survival and treatment outcome in breast cancer

artículo científico publicado en 2017

Tagging single nucleotide polymorphisms in cell cycle control genes and susceptibility to invasive epithelial ovarian cancer

artículo científico publicado en 2007

Tagging single nucleotide polymorphisms in the BRIP1 gene and susceptibility to breast and ovarian cancer

artículo científico publicado en 2007

Tagging single-nucleotide polymorphisms in antioxidant defense enzymes and susceptibility to breast cancer

artículo científico publicado en 2006

Tagging single-nucleotide polymorphisms in candidate oncogenes and susceptibility to ovarian cancer

artículo científico publicado en 2009

Tamoxifen and risk of contralateral breast cancer for BRCA1 and BRCA2 mutation carriers

artículo científico publicado en 2013

Targeted Resequencing of the Coding Sequence of 38 Genes Near Breast Cancer GWAS Loci in a Large Case-Control Study

artículo científico publicado en 2019

Targeted prostate cancer screening in men with mutations in BRCA1 and BRCA2 detects aggressive prostate cancer: preliminary analysis of the results of the IMPACT study

artículo científico publicado en 2010

Teacher questionnaire compared with observational data on effects of sex and sibling status on preschool behaviour

artículo científico publicado en 1984

Telomere length in prospective and retrospective cancer case-control studies

artículo científico publicado en 2010

Telomere length shows no association with BRCA1 and BRCA2 mutation status

scientific article published on 29 January 2014

Telomere structure and maintenance gene variants and risk of five cancer types

artículo científico publicado en 2016

Testicular microlithiasis as a familial risk factor for testicular germ cell tumour

artículo científico publicado en 2007

The ACE gene and Alzheimer's disease susceptibility

artículo científico publicado en 2000

The AIB1 Polyglutamine Repeat Does Not Modify Breast Cancer Risk in BRCA1 and BRCA2 Mutation Carriers

article

The BACE gene: genomic structure and candidate gene study in late-onset Alzheimer's disease.

artículo científico publicado en 2001

The BOADICEA model of genetic susceptibility to breast and ovarian cancer

artículo científico publicado en 2004

The BOADICEA model of genetic susceptibility to breast and ovarian cancers: updates and extensions

artículo científico publicado en 2008

The BOADICEA model of genetic susceptibility to breast and ovarian cancers: updates and extensions.

artículo científico publicado en 2008

The BRCA2 c.68-7T > A variant is not pathogenic: A model for clinical calibration of spliceogenicity

artículo científico publicado en 2018

The CASP8 -652 6N del promoter polymorphism and breast cancer risk: a multicenter study

artículo científico publicado en 2007

The CEPH consortium primary linkage map of human chromosome 10

artículo científico publicado en 1990

The CYP17A1 -34T > C polymorphism and breast cancer risk in BRCA1 and BRCA2 mutation carriers

artículo científico publicado en 2010

The Effects of Common Genetic Variants in Oncogenes on Ovarian Cancer Survival

The FANCM:p.Arg658* truncating variant is associated with risk of triple-negative breast cancer

scientific article published on 01 November 2019

The Influence of Number and Timing of Pregnancies on Breast Cancer Risk for Women With or Mutations

The International Testicular Cancer Linkage Consortium: a clinicopathologic descriptive analysis of 461 familial malignant testicular germ cell tumor kindred

artículo científico publicado en 2009

The KL-VS sequence variant of Klotho and cancer risk in BRCA1 and BRCA2 mutation carriers

artículo científico publicado en 2012

The OncoArray Consortium: A Network for Understanding the Genetic Architecture of Common Cancers

artículo científico publicado en 2016

The Relationship Between Micrometastases in the Bone Marrow, Histopathologic Features of the Primary Tumor in Breast Cancer and Prognosis

artículo científico publicado el 1 de julio de 1988

The Reliable Identification of Disease-Gene Associations

article

The SNP rs6500843 in 16p13.3 is associated with survival specifically among chemotherapy-treated breast cancer patients

artículo científico publicado en 2015

The TP53 Arg72Pro and MDM2 309G>T polymorphisms are not associated with breast cancer risk in BRCA1 and BRCA2 mutation carriers

artículo científico publicado en 2009

The UK national study of magnetic resonance imaging as a method of screening for breast cancer (MARIBS)

artículo científico publicado en 2002

The Y deletion gr/gr and susceptibility to testicular germ cell tumor

artículo científico publicado en 2005

The admixture maximum likelihood test to test for association between rare variants and disease phenotypes

artículo científico publicado el 6 de junio de 2013

The admixture maximum likelihood test: a novel experiment-wise test of association between disease and multiple SNPs

scientific article published on 01 November 2006

The androgen receptor CAG repeat polymorphism and modification of breast cancer risk in BRCA1 and BRCA2 mutation carriers

artículo científico publicado en 2005

The clinical and screening age-at-onset distribution for the MEN-2 syndrome

artículo científico publicado en 1989

The contribution of germline BRCA1 and BRCA2 mutations to familial ovarian cancer: no evidence for other ovarian cancer-susceptibility genes

artículo científico publicado en 1999

The contribution of inherited predisposition to cancer incidence

scientific article published on January 1990

The contribution of rare variation to prostate cancer heritability

artículo científico publicado en 2015

The contributions of breast density and common genetic variation to breast cancer risk

artículo científico publicado en 2015

The cost-utility of magnetic resonance imaging for breast cancer in BRCA1 mutation carriers aged 30–49

article published in 2007

The effect of sample size on polygenic hazard models for prostate cancer

artículo científico publicado en 2020

The effects of height and BMI on prostate cancer incidence and mortality: a Mendelian randomization study in 20,848 cases and 20,214 controls from the PRACTICAL consortium

artículo científico publicado en 2015

The evolutionary history of lethal metastatic prostate cancer

artículo científico publicado en 2015

The extent of linkage disequilibrium in four populations with distinct demographic histories

artículo científico publicado en 2000

The frequency of germ-line mutations in the breast cancer predisposition genes BRCA1 and BRCA2 in familial prostate cancer. The Cancer Research Campaign/British Prostate Group United Kingdom Familial Prostate Cancer Study Collaborators

article

The functional ALDH2 polymorphism is associated with breast cancer risk: A pooled analysis from the Breast Cancer Association Consortium.

artículo científico publicado en 2019

The genetic epidemiology of BRCA1. Breast Cancer Linkage Consortium

artículo científico publicado en 1994

The genetic epidemiology of breast cancer genes

artículo científico publicado en 2004

The genetic epidemiology of early-onset epithelial ovarian cancer: a population-based study

artículo científico publicado en 1999

The genetic epidemiology of prostate cancer and its clinical implications

artículo científico

The genetic interplay between body mass index, breast size and breast cancer risk: a Mendelian randomization analysis

scientific article published on 01 June 2019

The genetics of breast and ovarian cancer

artículo científico publicado en 1995

The genetics of familial breast cancer and their practical implications

artículo científico publicado en 1994

The heritability of mammographic breast density and circulating sex-hormone levels: two independent breast cancer risk factors

artículo científico publicado en 2012

The influence of obesity-related factors in the etiology of renal cell carcinoma-A mendelian randomization study

scientific article published on 03 January 2019

The inherited component of cancer

artículo científico publicado en 1994

The landscape of cancer genes and mutational processes in breast cancer

artículo científico publicado en 2012

The management of advanced testicular teratoma

artículo científico publicado en 1988

The pathology of familial breast cancer: predictive value of immunohistochemical markers estrogen receptor, progesterone receptor, HER-2, and p53 in patients with mutations in BRCA1 and BRCA2.

artículo científico publicado en 2002

The role of KRAS rs61764370 in invasive epithelial ovarian cancer: implications for clinical testing

artículo científico publicado en 2011

The role of genetic breast cancer susceptibility variants as prognostic factors

artículo científico publicado en 2012

The rs10993994 risk allele for prostate cancer results in clinically relevant changes in microseminoprotein-beta expression in tissue and urine

artículo científico publicado en 2010

The search for low-penetrance breast cancer genes.

artículo científico publicado en 2005

The study of nevi in British twins: Study design and description of the data set

artículo científico publicado el 1 de enero de 1992

Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies

artículo científico publicado en 2010

Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction

artículo científico publicado en 2021

Transcriptome-wide association study of breast cancer risk by estrogen-receptor status

artículo científico publicado en 2020

Truncating mutations in the Fanconi anemia J gene BRIP1 are low-penetrance breast cancer susceptibility alleles

article

Two ATM variants and breast cancer risk

artículo científico publicado en 2005

Two Novel Susceptibility Loci for Prostate Cancer in Men of African Ancestry.

artículo científico publicado en 2017

Two percent of men with early-onset prostate cancer harbor germline mutations in the BRCA2 gene

artículo científico publicado en 2002

Two truncating variants in FANCC and breast cancer risk

artículo científico publicado en 2019

Uncovering the Contribution of Moderate-Penetrance Susceptibility Genes to Breast Cancer by Whole-Exome Sequencing and Targeted Enrichment Sequencing of Candidate Genes in Women of European Ancestry

artículo científico publicado en 2022

Use of deep whole genome sequencing data to identify structure risk variants in breast cancer susceptibility genes.

artículo científico publicado en 2018

Use of the BOADICEA Web Application in clinical practice: appraisals by clinicians from various countries

artículo científico publicado en 2017

Using human genetics to understand the disease impacts of testosterone in men and women

artículo científico publicado en 2020

VEXOR: an integrative environment for prioritization of functional variants in fine-mapping analysis

artículo científico publicado en 2017

Validation of loci at 2q14.2 and 15q21.3 as risk factors for testicular cancer

artículo científico publicado en 2017

Validation of prostate cancer risk-related loci identified from genome-wide association studies using family-based association analysis: evidence from the International Consortium for Prostate Cancer Genetics (ICPCG)

artículo científico publicado en 2011

Variants in CHEK2 other than 1100delC do not make a major contribution to breast cancer susceptibility

artículo científico publicado en 2003

Variants in DNA double-strand break repair genes and breast cancer susceptibility

artículo científico publicado en 2002

Variants in genes encoding small GTPases and association with epithelial ovarian cancer susceptibility

artículo científico publicado en 2018

Variants near DMRT1, TERT and ATF7IP are associated with testicular germ cell cancer

artículo científico publicado en 2010

Variation in BRCA1 cancer risks by mutation position

artículo científico publicado en 2002

Variation in cancer risks, by mutation position, in BRCA2 mutation carriers

artículo científico publicado en 2001

Variation of risks of breast and ovarian cancer associated with different germline mutations of the BRCA2 gene

scientific article published on 01 January 1997

Where are the prostate cancer genes?—A summary of eight genome wide searches

artículo científico publicado el 1 de diciembre de 2003

Younger age-at-diagnosis for familial malignant testicular germ cell tumor

artículo científico publicado en 2009

[The genetics of medullary cancer of the thyroid]

scientific article published on 01 January 1988

pedigreejs: a web-based graphical pedigree editor

artículo científico publicado en 2017

rs2735383, located at a microRNA binding site in the 3'UTR of NBS1, is not associated with breast cancer risk

artículo científico publicado en 2016