Lista de obras - William Greenleaf - Dominio Público Uruguay

A Chromatin Basis for Cell Lineage and Disease Risk in the Human Pancreas

scientific article published on 22 August 2018

A Quantitative and Predictive Model for RNA Binding by Human Pumilio Proteins

scientific article published on 08 May 2019

A conditional system to specifically link disruption of protein-coding function with reporter expression in mice

artículo científico publicado en 2014

A pause sequence enriched at translation start sites drives transcription dynamics in vivo

artículo científico publicado en 2014

ATAC-see reveals the accessible genome by transposase-mediated imaging and sequencing

artículo científico publicado en 2016

ATAC-seq: A Method for Assaying Chromatin Accessibility Genome-Wide ⬇️

artículo científico publicado en 2015

An improved ATAC-seq protocol reduces background and enables interrogation of frozen tissues

An improved ATAC-seq protocol reduces background and enables interrogation of frozen tissues.

artículo científico publicado en 2017

An optical apparatus for rotation and trapping

artículo científico publicado en 2010

Applied force reveals mechanistic and energetic details of transcription termination

artículo científico publicado en 2008

ArchR is a scalable software package for integrative single-cell chromatin accessibility analysis

artículo científico publicado en 2021

Assaying the epigenome in limited numbers of cells

artículo científico publicado en 2014

Author Correction: Discovery of stimulation-responsive immune enhancers with CRISPR activation

scientific article published in Nature

Automated Design of Diverse Stand-Alone Riboswitches

scientific article published on 29 July 2019

Beyond the Linear Genome: Paired-End Sequencing as a Biophysical Tool

artículo científico publicado en 2015

Blind tests of RNA-protein binding affinity prediction

scientific article published on 08 April 2019

Brief Report: Cell Cycle Dynamics of Human Pluripotent Stem Cells Primed for Differentiation

artículo científico publicado en 2019

Challenges and recommendations for epigenomics in precision health.

artículo científico publicado en 2017

Chromatin Accessibility Landscape of Cutaneous T Cell Lymphoma and Dynamic Response to HDAC Inhibitors

artículo científico publicado en 2017

Chromatin accessibility and the regulatory epigenome

artículo científico publicado en 2019

Chromatin accessibility dynamics in a model of human forebrain development

artículo científico publicado en 2020

Chromatin accessibility dynamics reveal novel functional enhancers in C. elegans.

artículo científico publicado en 2017

Chromatin accessibility dynamics reveal novel functional enhancers inC. elegans

Chromatin-associated RNA sequencing (ChAR-seq) maps genome-wide RNA-to-DNA contacts.

artículo científico publicado en 2018

Compact RNA sensors for increasingly complex functions of multiple inputs

artículo científico publicado en 2024

Comprehensive and quantitative mapping of RNA-protein interactions across a transcribed eukaryotic genome

artículo científico publicado en 2017

Comprehensive sequence-to-function mapping of cofactor-dependent RNA catalysis in the glmS ribozyme

scientific article published on 03 April 2020

Corrigendum: Landscape of monoallelic DNA accessibility in mouse embryonic stem cells and neural progenitor cells.

artículo científico publicado en 2017

Coupled Single-Cell CRISPR Screening and Epigenomic Profiling Reveals Causal Gene Regulatory Networks

artículo científico publicado en 2018

Crowdsourced RNA design discovers diverse, reversible, efficient, self-contained molecular sensors

artículo científico publicado en 2019

Demonstration of protein cooperativity mediated by RNA structure using the human protein PUM2

scientific article published on 26 March 2019

Deterministic Somatic Cell Reprogramming Involves Continuous Transcriptional Changes Governed by Myc and Epigenetic-Driven Modules

scientific article published on 13 December 2018

Diff-seq: A high throughput sequencing-based mismatch detection assay for DNA variant enrichment and discovery

artículo científico publicado en 2018

Digital polymerase chain reaction in an array of femtoliter polydimethylsiloxane microreactors

artículo científico publicado en 2012

Direct observation of base-pair stepping by RNA polymerase

artículo científico publicado en 2005

Direct observation of hierarchical folding in single riboswitch aptamers

artículo científico publicado en 2008

Direct, High-Throughput Measurement of Quantitative RNA Affinity Landscapes

Discovery of stimulation-responsive immune enhancers with CRISPR activation.

artículo científico publicado en 2017

Dynamic chromatin regulatory landscape of human CAR T cell exhaustion

artículo científico publicado en 2021

Enhancer connectome in primary human cells identifies target genes of disease-associated DNA elements.

artículo científico publicado en 2017

Epigenetic signature of PD-1+ TCF1+ CD8 T cells that act as resource cells during chronic viral infection and respond to PD-1 blockade

artículo científico publicado en 2019

Epigenomics of human CD8 T cell differentiation and aging

artículo científico publicado en 2017

Exome sequencing identifies a DNAJB6 mutation in a family with dominantly-inherited limb-girdle muscular dystrophy

artículo científico publicado en 2014

Fluorogenic DNA sequencing in PDMS microreactors ⬇️

artículo científico publicado el 12 de junio de 2011

Genome-scale measurement of off-target activity using Cas9 toxicity in high-throughput screens

artículo científico publicado en 2017

HiChIP: efficient and sensitive analysis of protein-directed genome architecture

artículo científico publicado en 2016

HiChIRP reveals RNA-associated chromosome conformation

artículo científico publicado en 2019

High-Throughput Analysis Reveals Rules for Target RNA Binding and Cleavage by AGO2

artículo científico publicado en 2019

High-Throughput Investigation of Diverse Junction Elements in RNA Tertiary Folding

scientific article published on 28 June 2018

High-resolution mapping of cancer cell networks using co-functional interactions

High-resolution, single-molecule measurements of biomolecular motion

artículo científico publicado en 2007

High-throughput biochemical profiling reveals Cas9 off-target binding and unbinding heterogeneity

High-throughput biochemical profiling reveals sequence determinants of dCas9 off-target binding and unbinding

artículo científico publicado en 2017

High-throughput chromatin accessibility profiling at single-cell resolution

scientific article published in Nature Communications

High-throughput single-cell chromatin accessibility CRISPR screens enable unbiased identification of regulatory networks in cancer

artículo científico publicado en 2021

INO80 Chromatin Remodeling Coordinates Metabolic Homeostasis with Cell Division

artículo científico publicado en 2018

Identification of phagocytosis regulators using magnetic genome-wide CRISPR screens

artículo científico publicado en 2018

Identification of significantly mutated regions across cancer types highlights a rich landscape of functional molecular alterations

artículo científico publicado en 2015

Individuality and variation of personal regulomes in primary human T cells

artículo científico publicado en 2015

Integrated Single-Cell Analysis Maps the Continuous Regulatory Landscape of Human Hematopoietic Differentiation.

artículo científico publicado en 2018

Intertumoral Heterogeneity in SCLC Is Influenced by the Cell Type of Origin

artículo científico publicado en 2018

Joint single-cell DNA accessibility and protein epitope profiling reveals environmental regulation of epigenomic heterogeneity

artículo científico publicado en 2018

LKB1 inactivation modulates chromatin accessibility to drive metastatic progression

artículo científico publicado en 2021

Landscape of monoallelic DNA accessibility in mouse embryonic stem cells and neural progenitor cells

scientific article published on 23 January 2017

Landscape of stimulation-responsive chromatin across diverse human immune cells

scientific article published on 30 September 2019

Large-Scale, Quantitative Protein Assays on a High-Throughput DNA Sequencing Chip

artículo científico publicado en 2019

Lineage-specific and single-cell chromatin accessibility charts human hematopoiesis and leukemia evolution

artículo científico publicado en 2016

Lineage-specific dynamic and pre-established enhancer-promoter contacts cooperate in terminal differentiation.

artículo científico publicado en 2017

Linking RNA Sequence, Structure, and Function on Massively Parallel High-Throughput Sequencers

scientific article published on 01 October 2019

Long-range single-molecule mapping of chromatin accessibility in eukaryotes

artículo científico publicado en 2020

Massively parallel single-cell chromatin landscapes of human immune cell development and intratumoral T cell exhaustion

artículo científico publicado en 2019

Mitigation of off-target toxicity in CRISPR-Cas9 screens for essential non-coding elements

scientific article published on 06 September 2019

Molecule by molecule, the physics and chemistry of life: SMB 2007.

artículo científico publicado en 2007

Neutralizing Gatad2a-Chd4-Mbd3 Axis within the NuRD Complex Facilitates Deterministic Induction of Naive Pluripotency

Neutralizing Gatad2a-Chd4-Mbd3 Axis within the NuRD Complex Facilitates Deterministic Induction of Naïve Pluripotency

Neutralizing Gatad2a-Chd4-Mbd3/NuRD Complex Facilitates Deterministic Induction of Naive Pluripotency

artículo científico publicado en 2018

Nfib Promotes Metastasis through a Widespread Increase in Chromatin Accessibility

artículo científico publicado en 2016

Omega-3 Fatty Acids Activate Ciliary FFAR4 to Control Adipogenesis

scientific article published on 21 November 2019

Origin and differentiation of human memory CD8 T cells after vaccination

artículo científico publicado en 2017

Passive all-optical force clamp for high-resolution laser trapping

artículo científico publicado en 2005

Pulling out the 1%: whole-genome capture for the targeted enrichment of ancient DNA sequencing libraries

artículo científico publicado en 2013

Quantitative analysis of RNA-protein interactions on a massively parallel array reveals biophysical and evolutionary landscapes

artículo científico publicado en 2014

Rapid chromatin repression by Aire provides precise control of immune tolerance

artículo científico publicado en 2018

Reduced chromatin accessibility to CD4 T cell super-enhancers encompassing susceptibility loci of rheumatoid arthritis

artículo científico publicado en 2022

Satb1 integrates DNA binding site geometry and torsional stress to differentially target nucleosome-dense regions

scientific article published on 19 July 2019

Sequence-dependent RNA helix conformational preferences predictably impact tertiary structure formation

artículo científico publicado en 2019

Short tandem repeats bind transcription factors to tune eukaryotic gene expression

artículo científico publicado en 2023

Single-cell chromatin accessibility reveals principles of regulatory variation

artículo científico publicado en 2015

Single-cell epigenomic analyses implicate candidate causal variants at inherited risk loci for Alzheimer's and Parkinson's diseases

artículo científico publicado en 2020

Single-cell epigenomic variability reveals functional cancer heterogeneity

artículo científico publicado en 2017

Single-cell epigenomics maps the continuous regulatory landscape of human hematopoietic differentiation

Single-cell multiomic analysis identifies regulatory programs in mixed-phenotype acute leukemia

scientific article published on 02 December 2019

Single-cell transcriptomic analysis of the adult mouse spinal cord reveals molecular diversity of autonomic and skeletal motor neurons

Single-molecule studies of RNA polymerase: motoring along

artículo científico publicado en 2008

Single-molecule, motion-based DNA sequencing using RNA polymerase

artículo científico publicado en 2006

Structured nucleosome fingerprints enable high-resolution mapping of chromatin architecture within regulatory regions

artículo científico publicado en 2015

Systematic benchmarking of single-cell ATAC-sequencing protocols

artículo científico publicado en 2023

TOP2 synergizes with BAF chromatin remodeling for both resolution and formation of facultative heterochromatin

artículo científico publicado en 2017

The Molecular and Functional Foundations of Conducive Somatic Cell Reprogramming to Ground State Pluripotency

The chromatin accessibility landscape of primary human cancers

artículo científico publicado en 2018

The chromatin organization of a chlorarachniophyte nucleomorph genome

artículo científico publicado en 2022

The future of sequencing: convergence of intelligent design and market Darwinism

artículo científico publicado en 2014

Transcript-indexed ATAC-seq for precision immune profiling.

artículo científico publicado en 2018

Transient acquisition of pluripotency during somatic cell transdifferentiation with iPSC reprogramming factors

artículo científico publicado en 2015

Transposition of native chromatin for fast and sensitive epigenomic profiling of open chromatin, DNA-binding proteins and nucleosome position

artículo científico publicado en 2013

Unraveling the 3D genome: genomics tools for multiscale exploration

artículo científico

Unsupervised clustering and epigenetic classification of single cells.

artículo científico publicado en 2018

Variable chromatin structure revealed by in situ spatially correlated DNA cleavage mapping

artículo científico publicado en 2016

chromVAR: Inferring transcription factor variation from single-cell epigenomic data

chromVAR: inferring transcription-factor-associated accessibility from single-cell epigenomic data

artículo científico publicado en 2017

Lista de obras de William Greenleaf

A Chromatin Basis for Cell Lineage and Disease Risk in the Human Pancreas

A Quantitative and Predictive Model for RNA Binding by Human Pumilio Proteins

A conditional system to specifically link disruption of protein-coding function with reporter expression in mice

A pause sequence enriched at translation start sites drives transcription dynamics in vivo

ATAC-see reveals the accessible genome by transposase-mediated imaging and sequencing

ATAC-seq: A Method for Assaying Chromatin Accessibility Genome-Wide ⬇️

An improved ATAC-seq protocol reduces background and enables interrogation of frozen tissues

An improved ATAC-seq protocol reduces background and enables interrogation of frozen tissues.

An optical apparatus for rotation and trapping

Applied force reveals mechanistic and energetic details of transcription termination

ArchR is a scalable software package for integrative single-cell chromatin accessibility analysis

Assaying the epigenome in limited numbers of cells

Author Correction: Discovery of stimulation-responsive immune enhancers with CRISPR activation

Automated Design of Diverse Stand-Alone Riboswitches

Beyond the Linear Genome: Paired-End Sequencing as a Biophysical Tool

Blind tests of RNA-protein binding affinity prediction

Brief Report: Cell Cycle Dynamics of Human Pluripotent Stem Cells Primed for Differentiation

Challenges and recommendations for epigenomics in precision health.

Chromatin Accessibility Landscape of Cutaneous T Cell Lymphoma and Dynamic Response to HDAC Inhibitors

Chromatin accessibility and the regulatory epigenome

Chromatin accessibility dynamics in a model of human forebrain development

Chromatin accessibility dynamics reveal novel functional enhancers in C. elegans.

Chromatin accessibility dynamics reveal novel functional enhancers inC. elegans

Chromatin-associated RNA sequencing (ChAR-seq) maps genome-wide RNA-to-DNA contacts.

Compact RNA sensors for increasingly complex functions of multiple inputs

Comprehensive and quantitative mapping of RNA-protein interactions across a transcribed eukaryotic genome

Comprehensive sequence-to-function mapping of cofactor-dependent RNA catalysis in the glmS ribozyme

Corrigendum: Landscape of monoallelic DNA accessibility in mouse embryonic stem cells and neural progenitor cells.

Coupled Single-Cell CRISPR Screening and Epigenomic Profiling Reveals Causal Gene Regulatory Networks

Crowdsourced RNA design discovers diverse, reversible, efficient, self-contained molecular sensors

Demonstration of protein cooperativity mediated by RNA structure using the human protein PUM2

Deterministic Somatic Cell Reprogramming Involves Continuous Transcriptional Changes Governed by Myc and Epigenetic-Driven Modules

Diff-seq: A high throughput sequencing-based mismatch detection assay for DNA variant enrichment and discovery

Digital polymerase chain reaction in an array of femtoliter polydimethylsiloxane microreactors

Direct observation of base-pair stepping by RNA polymerase

Direct observation of hierarchical folding in single riboswitch aptamers

Direct, High-Throughput Measurement of Quantitative RNA Affinity Landscapes

Discovery of stimulation-responsive immune enhancers with CRISPR activation.

Dynamic chromatin regulatory landscape of human CAR T cell exhaustion

Enhancer connectome in primary human cells identifies target genes of disease-associated DNA elements.

Epigenetic signature of PD-1+ TCF1+ CD8 T cells that act as resource cells during chronic viral infection and respond to PD-1 blockade

Epigenomics of human CD8 T cell differentiation and aging

Exome sequencing identifies a DNAJB6 mutation in a family with dominantly-inherited limb-girdle muscular dystrophy

Fluorogenic DNA sequencing in PDMS microreactors ⬇️

Genome-scale measurement of off-target activity using Cas9 toxicity in high-throughput screens

HiChIP: efficient and sensitive analysis of protein-directed genome architecture

HiChIRP reveals RNA-associated chromosome conformation

High-Throughput Analysis Reveals Rules for Target RNA Binding and Cleavage by AGO2

High-Throughput Investigation of Diverse Junction Elements in RNA Tertiary Folding

High-resolution mapping of cancer cell networks using co-functional interactions

High-resolution, single-molecule measurements of biomolecular motion

High-throughput biochemical profiling reveals Cas9 off-target binding and unbinding heterogeneity

High-throughput biochemical profiling reveals sequence determinants of dCas9 off-target binding and unbinding

High-throughput chromatin accessibility profiling at single-cell resolution

High-throughput single-cell chromatin accessibility CRISPR screens enable unbiased identification of regulatory networks in cancer

INO80 Chromatin Remodeling Coordinates Metabolic Homeostasis with Cell Division

Identification of phagocytosis regulators using magnetic genome-wide CRISPR screens

Identification of significantly mutated regions across cancer types highlights a rich landscape of functional molecular alterations

Individuality and variation of personal regulomes in primary human T cells

Integrated Single-Cell Analysis Maps the Continuous Regulatory Landscape of Human Hematopoietic Differentiation.

Intertumoral Heterogeneity in SCLC Is Influenced by the Cell Type of Origin

Joint single-cell DNA accessibility and protein epitope profiling reveals environmental regulation of epigenomic heterogeneity

LKB1 inactivation modulates chromatin accessibility to drive metastatic progression

Landscape of monoallelic DNA accessibility in mouse embryonic stem cells and neural progenitor cells

Landscape of stimulation-responsive chromatin across diverse human immune cells

Large-Scale, Quantitative Protein Assays on a High-Throughput DNA Sequencing Chip

Lineage-specific and single-cell chromatin accessibility charts human hematopoiesis and leukemia evolution

Lineage-specific dynamic and pre-established enhancer-promoter contacts cooperate in terminal differentiation.

Linking RNA Sequence, Structure, and Function on Massively Parallel High-Throughput Sequencers

Long-range single-molecule mapping of chromatin accessibility in eukaryotes

Massively parallel single-cell chromatin landscapes of human immune cell development and intratumoral T cell exhaustion

Mitigation of off-target toxicity in CRISPR-Cas9 screens for essential non-coding elements

Molecule by molecule, the physics and chemistry of life: SMB 2007.

Neutralizing Gatad2a-Chd4-Mbd3 Axis within the NuRD Complex Facilitates Deterministic Induction of Naive Pluripotency

Neutralizing Gatad2a-Chd4-Mbd3 Axis within the NuRD Complex Facilitates Deterministic Induction of Naïve Pluripotency

Neutralizing Gatad2a-Chd4-Mbd3/NuRD Complex Facilitates Deterministic Induction of Naive Pluripotency

Nfib Promotes Metastasis through a Widespread Increase in Chromatin Accessibility

Omega-3 Fatty Acids Activate Ciliary FFAR4 to Control Adipogenesis

Origin and differentiation of human memory CD8 T cells after vaccination