Lista de obras - Maria A Garcia - Dominio Público Uruguay

1-(Benzenesulfonyl)-1,5-dihydro-4,1-benzoxazepine as a new scaffold for the design of antitumor compounds

artículo científico publicado en 2017

5-Fluorouracil derivatives: a patent review (2012 - 2014).

artículo científico

A formulation of pancreatic pro-enzymes provides potent anti-tumour efficacy: a pilot study focused on pancreatic and ovarian cancer.

artículo científico publicado en 2017

Activating Transcription Factor 4 Modulates TGFβ-Induced Aggressiveness in Triple-Negative Breast Cancer via SMAD2/3/4 and mTORC2 Signaling

scientific article published on 16 July 2018

Activation of NF-kB pathway by virus infection requires Rb expression

artículo científico publicado en 2009

Activation of the double-stranded RNA-dependent protein kinase PKR by small ubiquitin-like modifier (SUMO).

artículo científico publicado en 2014

Anti-apoptotic and oncogenic properties of the dsRNA-binding protein of vaccinia virus, E3L.

artículo científico publicado en 2002

Bozepinib, a novel small antitumor agent, induces PKR-mediated apoptosis and synergizes with IFNα triggering apoptosis, autophagy and senescence

artículo científico publicado en 2013

Cardiomyogenic differentiation potential of human endothelial progenitor cells isolated from patients with myocardial infarction

artículo científico publicado en 2014

Caspase 9 activation by the dsRNA-dependent protein kinase, PKR: molecular mechanism and relevance.

artículo científico publicado en 2002

Clinical and therapeutic potential of protein kinase PKR in cancer and metabolism

artículo científico publicado en 2017

Clinical failure of nanoparticles in cancer: mimicking nature's solutions

scientific article published on 24 September 2020

Control of virus infection by tumour suppressors.

artículo científico publicado en 2007

Enantiospecific synthesis of heterocycles linked to purines: different apoptosis modulation of enantiomers in breast cancer cells

artículo científico publicado en 2013

How Can Nanotechnology Help to Repair the Body? Advances in Cardiac, Skin, Bone, Cartilage and Nerve Tissue Regeneration

artículo científico

Human gene profiling in response to the active protein kinase, interferon-induced serine/threonine protein kinase (PKR), in infected cells. Involvement of the transcription factor ATF-3 IN PKR-induced apoptosis.

artículo científico publicado en 2006

In vitro treatment of carcinoma cell lines with pancreatic (pro)enzymes suppresses the EMT programme and promotes cell differentiation

scientific article published on 16 May 2013

Involvement of PKR and RNase L in translational control and induction of apoptosis after Hepatitis C polyprotein expression from a vaccinia virus recombinant

artículo científico publicado en 2005

Low adherent cancer cell subpopulations are enriched in tumorigenic and metastatic epithelial-to-mesenchymal transition-induced cancer stem-like cells.

artículo científico publicado en 2016

Mesenchymal stem cell's secretome promotes selective enrichment of cancer stem-like cells with specific cytogenetic profile

scientific article published on 05 May 2018

New (RS)-benzoxazepin-purines with antitumour activity: The chiral switch from (RS)-2,6-dichloro-9-[1-(p-nitrobenzenesulfonyl)-1,2,3,5-tetrahydro-4,1-benzoxazepin-3-yl]-9H-purine.

artículo científico publicado en 2010

Pancreatic (pro)enzymes treatment suppresses BXPC-3 pancreatic Cancer Stem Cell subpopulation and impairs tumour engrafting

artículo científico publicado en 2019

Polymers, scaffolds and bioactive molecules with therapeutic properties in osteochondral pathologies: what's new?

artículo científico publicado en 2016

Resistance to viral infection of super p53 mice.

artículo científico publicado en 2005

SIRT1 stabilizes PML promoting its sumoylation

artículo científico publicado en 2010

Synthesis and anticancer activity of (RS)-9-(2,3-dihydro-1,4-benzoxaheteroin-2-ylmethyl)-9H-purines.

artículo científico publicado en 2011

Synthesis and anticancer activity of the (R,S)-benzofused 1,5-oxathiepine moiety tethered to purines through alkylidenoxy linkers.

artículo científico publicado en 2011

The catalytic activity of dsRNA-dependent protein kinase, PKR, is required for NF-kappaB activation.

artículo científico publicado en 2001

The chemotherapeutic drug 5-fluorouracil promotes PKR-mediated apoptosis in a p53-independent manner in colon and breast cancer cells

artículo científico publicado en 2011

The dsRNA protein kinase PKR: virus and cell control

artículo científico publicado en 2007

The impact of PKR activation: from neurodegeneration to cancer.

artículo científico

Uncovering Tumour Heterogeneity through PKR and nc886 Analysis in Metastatic Colon Cancer Patients Treated with 5-FU-Based Chemotherapy

scientific article published on 07 February 2020

Validation of suitable normalizers for miR expression patterns analysis covering tumour heterogeneity.

artículo científico publicado en 2017

Lista de obras de Maria A Garcia

1-(Benzenesulfonyl)-1,5-dihydro-4,1-benzoxazepine as a new scaffold for the design of antitumor compounds

5-Fluorouracil derivatives: a patent review (2012 - 2014).

A formulation of pancreatic pro-enzymes provides potent anti-tumour efficacy: a pilot study focused on pancreatic and ovarian cancer.

Activating Transcription Factor 4 Modulates TGFβ-Induced Aggressiveness in Triple-Negative Breast Cancer via SMAD2/3/4 and mTORC2 Signaling

Activation of NF-kB pathway by virus infection requires Rb expression

Activation of the double-stranded RNA-dependent protein kinase PKR by small ubiquitin-like modifier (SUMO).

Anti-apoptotic and oncogenic properties of the dsRNA-binding protein of vaccinia virus, E3L.

Bozepinib, a novel small antitumor agent, induces PKR-mediated apoptosis and synergizes with IFNα triggering apoptosis, autophagy and senescence

Cardiomyogenic differentiation potential of human endothelial progenitor cells isolated from patients with myocardial infarction

Caspase 9 activation by the dsRNA-dependent protein kinase, PKR: molecular mechanism and relevance.

Clinical and therapeutic potential of protein kinase PKR in cancer and metabolism

Clinical failure of nanoparticles in cancer: mimicking nature's solutions

Control of virus infection by tumour suppressors.

Enantiospecific synthesis of heterocycles linked to purines: different apoptosis modulation of enantiomers in breast cancer cells

How Can Nanotechnology Help to Repair the Body? Advances in Cardiac, Skin, Bone, Cartilage and Nerve Tissue Regeneration

Human gene profiling in response to the active protein kinase, interferon-induced serine/threonine protein kinase (PKR), in infected cells. Involvement of the transcription factor ATF-3 IN PKR-induced apoptosis.

In vitro treatment of carcinoma cell lines with pancreatic (pro)enzymes suppresses the EMT programme and promotes cell differentiation

Involvement of PKR and RNase L in translational control and induction of apoptosis after Hepatitis C polyprotein expression from a vaccinia virus recombinant

Low adherent cancer cell subpopulations are enriched in tumorigenic and metastatic epithelial-to-mesenchymal transition-induced cancer stem-like cells.

Mesenchymal stem cell's secretome promotes selective enrichment of cancer stem-like cells with specific cytogenetic profile

New (RS)-benzoxazepin-purines with antitumour activity: The chiral switch from (RS)-2,6-dichloro-9-[1-(p-nitrobenzenesulfonyl)-1,2,3,5-tetrahydro-4,1-benzoxazepin-3-yl]-9H-purine.

Pancreatic (pro)enzymes treatment suppresses BXPC-3 pancreatic Cancer Stem Cell subpopulation and impairs tumour engrafting

Polymers, scaffolds and bioactive molecules with therapeutic properties in osteochondral pathologies: what's new?

Resistance to viral infection of super p53 mice.

SIRT1 stabilizes PML promoting its sumoylation

Synthesis and anticancer activity of (RS)-9-(2,3-dihydro-1,4-benzoxaheteroin-2-ylmethyl)-9H-purines.

Synthesis and anticancer activity of the (R,S)-benzofused 1,5-oxathiepine moiety tethered to purines through alkylidenoxy linkers.

The catalytic activity of dsRNA-dependent protein kinase, PKR, is required for NF-kappaB activation.

The chemotherapeutic drug 5-fluorouracil promotes PKR-mediated apoptosis in a p53-independent manner in colon and breast cancer cells

The dsRNA protein kinase PKR: virus and cell control

The impact of PKR activation: from neurodegeneration to cancer.

Uncovering Tumour Heterogeneity through PKR and nc886 Analysis in Metastatic Colon Cancer Patients Treated with 5-FU-Based Chemotherapy

Validation of suitable normalizers for miR expression patterns analysis covering tumour heterogeneity.