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2D Difference Gel Electrophoresis Analysis of Different Time Points during the Course of Neoplastic Transformation of Human Mammary Epithelial Cells

artículo científico publicado el 20 de diciembre de 2010

A Novel Combination of Withaferin A and Sulforaphane Inhibits Epigenetic Machinery, Cellular Viability and Induces Apoptosis of Breast Cancer Cells

artículo científico publicado en 2017

A Novel Combinatorial Epigenetic Therapy Using Resveratrol and Pterostilbene for Restoring Estrogen Receptor-α (ERα) Expression in ERα-Negative Breast Cancer Cells

artículo científico publicado en 2016

A Novel Prodrug of Epigallocatechin-3-gallate: Differential Epigenetic hTERT Repression in Human Breast Cancer Cells

artículo científico publicado el 16 de marzo de 2011

A method to detect DNA methyltransferase I gene transcription in vitro in aging systems

artículo científico publicado en 2007

A method to study the expression of DNA methyltransferases in aging systems in vitro

artículo científico publicado en 2007

Activity, function, and gene regulation of the catalytic subunit of telomerase (hTERT)

artículo científico publicado en 2001

Advances in Epigenetic Technology

artículo científico publicado el 1 de enero de 2011

Age-related epigenetic drift and phenotypic plasticity loss: implications in prevention of age-related human diseases

artículo científico publicado en 2016

Aging and energetics' 'Top 40' future research opportunities 2010-2013.

artículo científico publicado en 2014

Aging cell culture: methods and observations

artículo científico publicado en 2007

Aging, cancer and nutrition: the DNA methylation connection

artículo científico publicado en 2003

An integrated analysis of the effects of maternal broccoli sprouts exposure on transcriptome and methylome in prevention of offspring mammary cancer

artículo científico publicado en 2022

Analysis in Escherichia coli of the effects of in vivo CpG methylation catalyzed by the cloned murine maintenance methyltransferase

artículo científico publicado en 1998

Analysis of biomarkers of caloric restriction in aging cells

scientific article published on January 2013

Analysis of telomerase activity and detection of its catalytic subunit, hTERT.

artículo científico publicado en 2003

Assessment of telomere length and factors that contribute to its stability

artículo científico publicado en 2003

Bioactive dietary supplements reactivate ER expression in ER-negative breast cancer cells by active chromatin modifications

artículo científico publicado en 2012

Carbohydrate metabolism in transforming lymphocytes from the aged

scientific article published on 01 June 1985

Cell senescence culturing methods.

artículo científico publicado en 2013

Collaborative Molecular Epidemiology Study of Metabolic Dysregulation, DNA Methylation, and Breast Cancer Risk Among Nigerian Women: MEND Study Objectives and Design

artículo científico publicado en 2019

Combinational Proanthocyanidins and Resveratrol Synergistically Inhibit Human Breast Cancer Cells and Impact Epigenetic⁻Mediating Machinery

artículo científico publicado en 2018

Combinatorial Epigenetics Impact of Polyphenols and Phytochemicals in Cancer Prevention and Therapy

artículo científico publicado en 2019

Combinatorial PX-866 and Raloxifene Decrease Rb Phosphorylation, Cyclin E2 Transcription, and Proliferation of MCF-7 Breast Cancer Cells

artículo científico publicado en 2015

Combinatorial bioactive botanicals re-sensitize tamoxifen treatment in ER-negative breast cancer via epigenetic reactivation of ERα expression

artículo científico publicado en 2017

Combinatorial epigenetic mechanisms and efficacy of early breast cancer inhibition by nutritive botanicals

artículo científico publicado en 2016

Combined Broccoli Sprouts and Green Tea Polyphenols Contribute to the Prevention of Estrogen Receptor-Negative Mammary Cancer via Cell Cycle Arrest and Inducing Apoptosis in HER2/neu Mice

artículo científico publicado en 2020

Combined Chromatin Immunoprecipitation and Bisulfite Methylation Sequencing Analysis

artículo científico publicado el 1 de enero de 2011

Computational methods and next-generation sequencing approaches to analyze epigenetics data: Profiling of methods and applications

scientific article published on 14 September 2020

Control mechanisms in the regulation of telomerase reverse transcriptase expression in differentiating human teratocarcinoma cells

artículo científico publicado en 2003

Control of methylation spreading in synthetic DNA sequences by the murine DNA methyltransferase

artículo científico publicado el 20 de junio de 1997

Could epigenetics help explain racial disparities in chronic pain?

artículo científico publicado en 2019

Culture kinetics of glycolytic enzyme induction, glucose utilization, and thymidine incorporation of extended-exposure phytohemagglutinin-stimulated human lymphocytes

artículo científico publicado en 1985

DNA methylation detection: bisulfite genomic sequencing analysis

artículo científico publicado en 2011

DNA methylation impacts on learning and memory in aging

artículo científico publicado en 2007

DNA methylation methods: global DNA methylation and methylomic analyses

artículo científico publicado en 2020

Decreased protein synthesis of transforming lymphocytes from aged humans: relationship to impaired mitogenesis with age

artículo científico publicado en 1985

Dietary epigenetics in cancer and aging

artículo científico publicado en 2014

Differential expression of epigenetic modulators during human embryonic stem cell differentiation

artículo científico publicado en 2008

Differential maintenance and de novo methylating activity by three DNA methyltransferases in aging and immortalized fibroblasts

artículo científico publicado en 2002

Display of adenoregulin with a novel Pichia pastoris cell surface display system

artículo científico publicado en 2007

Down-regulation of hTERT and Cyclin D1 transcription via PI3K/Akt and TGF-β pathways in MCF-7 Cancer cells with PX-866 and Raloxifene

artículo científico publicado en 2016

EGCG down-regulates telomerase in human breast carcinoma MCF-7 cells, leading to suppression of cell viability and induction of apoptosis.

artículo científico publicado en 2004

EGCG inhibits mammary cancer cell migration through inhibition of nitric oxide synthase and guanylate cyclase

artículo científico publicado en 2008

Effects of SAHA and EGCG on Growth Potentiation of Triple-Negative Breast Cancer Cells

scientific article published on 27 December 2018

Enhancement of Cisplatin-Mediated Apoptosis in Ovarian Cancer Cells through Potentiating G2/M Arrest and p21 Upregulation by Combinatorial Epigallocatechin Gallate and Sulforaphane

artículo científico publicado en 2013

Epigallocatechin gallate and sulforaphane combination treatment induce apoptosis in paclitaxel-resistant ovarian cancer cells through hTERT and Bcl-2 down-regulation.

artículo científico publicado en 2013

Epigenetic Regulation of Epidermal Stem Cell Biomarkers and Their Role in Wound Healing

artículo científico publicado en 2016

Epigenetic and genetic mechanisms contribute to telomerase inhibition by EGCG

artículo científico publicado en 2008

Epigenetic biomarkers: Current strategies and future challenges for their use in the clinical laboratory.

artículo científico publicado en 2017

Epigenetic control of telomerase and modes of telomere maintenance in aging and abnormal systems

artículo científico publicado en 2005

Epigenetic diet: impact on the epigenome and cancer

artículo científico publicado el 1 de agosto de 2011

Epigenetic linkage of aging, cancer and nutrition

artículo científico publicado en 2015

Epigenetic modifications of the Estrogen receptor beta gene in epithelial ovarian cancer cells

artículo científico publicado en 2009

Epigenetic reactivation of estrogen receptor-α (ERα) by genistein enhances hormonal therapy sensitivity in ERα-negative breast cancer

artículo científico publicado en 2013

Epigenetic reactivation of p21CIP1/WAF1 and KLOTHO by a combination of bioactive dietary supplements is partially ERα-dependent in ERα-negative human breast cancer cells

artículo científico publicado en 2015

Epigenetic regulation of caloric restriction in aging

artículo científico publicado el 25 de agosto de 2011

Epigenetic regulation of human telomerase reverse transcriptase promoter activity during cellular differentiation

artículo científico publicado en 2004

Epigenetic regulation of multiple tumor-related genes leads to suppression of breast tumorigenesis by dietary genistein

artículo científico publicado en 2013

Epigenetic regulation of telomerase in retinoid-induced differentiation of human leukemia cells

artículo científico publicado en 2008

Epigenetic regulation of thy-1 by histone deacetylase inhibitor in rat lung fibroblasts.

artículo científico publicado en 2010

Epigenetic targets of bioactive dietary components for cancer prevention and therapy

artículo científico publicado el 1 de diciembre de 2010

Epigenetic-based combinatorial resveratrol and pterostilbene alters DNA damage response by affecting SIRT1 and DNMT enzyme expression, including SIRT1-dependent γ-H2AX and telomerase regulation in triple-negative breast cancer

artículo científico publicado en 2015

Epigenomics of ovarian cancer and its chemoprevention

artículo científico publicado en 2011

Erratum to "Down-regulation of hTERT and Cyclin D1 transcription via PI3K/Akt and TGF-β pathways in MCF-7 cancer cells with PX-866 and Raloxifene" [Exp. Cell Res. 344 (2016) 95-102]

artículo científico publicado en 2016

Evidence of extra-telomeric effects of hTERT and its regulation involving a feedback loop

artículo científico publicado en 2006

Expression of intracellular biochemical defects of lymphocytes in aging: proposal of a general aging mechanism which is not cell-specific

artículo científico publicado en 1986

Gene expression of carbohydrate metabolism in cellular senescence and aging

artículo científico publicado en 1987

Gene-environment interactions and epigenetic basis of human diseases

artículo científico publicado en 2008

Genetic and epigenetic modulation of telomerase activity in development and disease

artículo científico publicado en 2004

Genistein depletes telomerase activity through cross-talk between genetic and epigenetic mechanisms

artículo científico publicado en 2009

Glucose restriction can extend normal cell lifespan and impair precancerous cell growth through epigenetic control of hTERT and p16 expression

artículo científico publicado en 2009

Identification of DNA methylation associated enrichment pathways in adults with non-specific chronic low back pain

artículo científico publicado en 2020

Impact of Epigenetic Dietary Components on Cancer through Histone Modifications

artículo científico

Impact of Nutrition on Non-Coding RNA Epigenetics in Breast and Gynecological Cancer

artículo científico publicado en 2015

Impact of epigenetic dietary compounds on transgenerational prevention of human diseases

artículo científico publicado en 2013

Impact of genistein on the gut microbiome of humanized mice and its role in breast tumor inhibition

artículo científico publicado en 2017

Impact on DNA methylation in cancer prevention and therapy by bioactive dietary components

artículo científico publicado en 2010

Impaired glycolysis of human lymphocytes during aging

artículo científico publicado el 1 de diciembre de 1981

Increased lability of triosephosphate isomerase in progeria and Werner's syndrome fibroblasts

artículo científico publicado en 1982

Induction of endogenous telomerase (hTERT) by c-Myc in WI-38 fibroblasts transformed with specific genetic elements

artículo científico publicado el 16 de octubre de 2003

Influences of diet and the gut microbiome on epigenetic modulation in cancer and other diseases

artículo científico publicado en 2015

Insufficient DNA methylation affects healthy aging and promotes age-related health problems

artículo científico publicado en 2011

Loss of the human polycomb group protein BMI1 promotes cancer-specific cell death

artículo científico publicado en 2006

Mammalian DNA (Cytosine-5-)-methyltransferase Expressed in Escherichia coli, Purified and Characterized

artículo científico publicado el 4 de agosto de 1995

Maternal epigenetic regulation contributes to prevention of estrogen receptor-negative mammary cancer with broccoli sprout consumption

artículo científico publicado en 2020

Mechanisms for methylation-mediated gene silencing and aging

artículo científico publicado en 1993

Mechanisms for telomerase gene control in aging cells and tumorigenesis.

artículo científico publicado en 2001

Mechanisms for the Inhibition of Colon Cancer Cells by Sulforaphane through Epigenetic Modulation of MicroRNA-21 and Human Telomerase Reverse Transcriptase (hTERT) Down-regulation

artículo científico publicado en 2017

Medicinal chemistry of the epigenetic diet and caloric restriction

artículo científico publicado en 2013

Methods of epigenetic analysis

artículo científico publicado en 2004

Methods of telomerase inhibition

artículo científico publicado en 2007

Methylated-CpG Island Recovery Assay

artículo científico publicado en 2011

MicroRNAs and Epigenetics Strategies to Reverse Breast Cancer

scientific article published on 08 October 2019

MicroRNAs: an emerging science in cancer epigenetics

artículo científico

Mitochondrial regulation of epigenetics and its role in human diseases

artículo científico publicado en 2012

Molecular basis of the accumulation of abnormal proteins in progeria and aging fibroblasts

Molecular mechanisms for inhibition of colon cancer cells by combined epigenetic-modulating epigallocatechin gallate and sodium butyrate

artículo científico publicado en 2014

Molecular resurrection of an extinct ancestral promoter for mouse L1.

artículo científico publicado en 1994

Nutritional combinatorial impact on the gut microbiota and plasma short-chain fatty acids levels in the prevention of mammary cancer in Her2/neu estrogen receptor-negative transgenic mice

scientific article published on 31 December 2020

Pathway modulations and epigenetic alterations in ovarian tumorbiogenesis

scientific article published on April 2014

Polyphenols and aging

artículo científico publicado en 2010

Prenatal epigenetics diets play protective roles against environmental pollution

artículo científico publicado en 2019

Profiling DNA methylation by bisulfite genomic sequencing: problems and solutions

artículo científico publicado en 2004

Proteolytic modification of human phosphoglycerate kinase from lymphoblasts

scientific article published on 01 November 1980

Pterostilbene down-regulates hTERT at physiological concentrations in breast cancer cells: Potentially through the inhibition of cMyc.

artículo científico publicado en 2017

RETRACTED: Aberrant DNA hypermethylation patterns lead to transcriptional silencing of tumor suppressor genes in UVB-exposed skin and UVB-induced skin tumors of mice

artículo científico publicado el 24 de diciembre de 2010

RNA interference using a plasmid construct expressing short-hairpin RNA

artículo científico publicado en 2007

Real-time methylomic aberrations during initiation and progression of induced human mammary epithelial cell tumorigenesis

artículo científico publicado en 2013

Regulation of the Telomerase Reverse Transcriptase Subunit through Epigenetic Mechanisms

artículo científico publicado en 2016

Regulation of the human catalytic subunit of telomerase (hTERT).

artículo científico publicado en 2012

Retinoid-induced histone deacetylation inhibits telomerase activity in estrogen receptor-negative breast cancer cells.

artículo científico publicado en 2009

Retrovirus-mediated RNA interference. Targeting hTERT through stable expression of short-hairpin RNA.

artículo científico publicado en 2007

Role of protein molecular and metabolic aberrations in aging, in the physiologic decline of the aged, and in age-associated diseases

artículo científico publicado en 1986

SAHA and EGCG Promote Apoptosis in Triple-negative Breast Cancer Cells, Possibly Through the Modulation of cIAP2

artículo científico publicado en 2020

Strategies targeting telomerase inhibition

scientific article published on 28 October 2008

Sulforaphane causes epigenetic repression of hTERT expression in human breast cancer cell lines

artículo científico publicado en 2010

Synergistic epigenetic reactivation of estrogen receptor-α (ERα) by combined green tea polyphenol and histone deacetylase inhibitor in ERα-negative breast cancer cells

artículo científico publicado el 14 de octubre de 2010

Systematic integrated analyses of methylomic and transcriptomic impacts of early combined botanicals on estrogen receptor-negative mammary cancer

artículo científico publicado en 2021

Targeting Telomeres and Telomerase: Studies in Aging and Disease Utilizing CRISPR/Cas9 Technology

artículo científico publicado en 2019

Targeting cancer epigenetics with CRISPR-dCAS9: Principles and prospects

artículo científico publicado en 2020

Techniques for analysis of biological aging

artículo científico publicado en 2007

Telomerase inhibition by retinoids precedes cytodifferentiation of leukemia cells and may contribute to terminal differentiation

artículo científico publicado en 2004

Telomerase inhibition in cancer therapeutics: molecular-based approaches

artículo científico publicado en 2006

Telomerase, telomerase inhibition, and cancer

artículo científico publicado en 2003

Telomeres and telomerase: basic science implications for aging

artículo científico publicado en 2001

Telomeres, telomerase, and telomerase inhibition: clinical implications for cancer

artículo científico publicado en 2003

Temporal Efficacy of a Sulforaphane-Based Broccoli Sprout Diet in Prevention of Breast Cancer through Modulation of Epigenetic Mechanisms

artículo científico publicado en 2018

The Effects of Combinatorial Genistein and Sulforaphane in Breast Tumor Inhibition: Role in Epigenetic Regulation.

artículo científico publicado en 2018

The Epigenetic Connection Between the Gut Microbiome in Obesity and Diabetes

artículo científico publicado en 2019

The Epigenetic Impact of Cruciferous Vegetables on Cancer Prevention

artículo científico publicado en 2015

The Epigenetic Link between Polyphenols, Aging and Age-Related Diseases

scientific article published on 18 September 2020

The Novel Retinoid, 9cUAB30, Inhibits Telomerase and Induces Apoptosis in HL60 Cells

artículo científico publicado en 2008

The Role of Non-coding RNAs and Isothiocyanates in Cancer.

artículo científico publicado en 2018

The effect of age on the accumulation of labile triosephosphate isomerase and thymidine incorporation in pokeweed mitogen stimulated human lymphocytes

scientific article published on 01 July 1984

The effects of aging on phosphofructokinase induction during lymphocyte mitogenesis in relation to DNA and protein synthesis

artículo científico publicado en 1987

The impact of metabolism on DNA methylation

artículo científico publicado en 2005

The influence of an epigenetics diet on the cancer epigenome.

artículo científico publicado en 2017

The low-toxicity 9-cis UAB30 novel retinoid down-regulates the DNA methyltransferases and has anti-telomerase activity in human breast cancer cells

artículo científico publicado en 2007

The protein synthetic surge in response to mitogen triggers high glycolytic enzyme levels in human lymphocytes and occurs prior to DNA synthesis

artículo científico publicado en 1990

The role of nutraceuticals in chemoprevention and chemotherapy and their clinical outcomes

artículo científico publicado en 2011

The transposon-driven evolutionary origin and basis of histone deacetylase functions and limitations in disease prevention

artículo científico publicado en 2011

Thy-1 promoter hypermethylation: a novel epigenetic pathogenic mechanism in pulmonary fibrosis

artículo científico publicado en 2008

Transcriptional control of the DNA methyltransferases is altered in aging and neoplastically-transformed human fibroblasts

artículo científico publicado el 1 de octubre de 2003

Transforming Cancer Epigenetics Using Nutritive Approaches and Non-coding RNAs

artículo científico publicado en 2017

Withaferin A and sulforaphane regulate breast cancer cell cycle progression through epigenetic mechanisms.

artículo científico publicado en 2018

hTERT knockdown in human embryonic kidney cells using double-stranded RNA

artículo científico publicado en 2007

p16INK4a Suppression by Glucose Restriction Contributes to Human Cellular Lifespan Extension through SIRT1-Mediated Epigenetic and Genetic Mechanisms

artículo científico publicado el 24 de febrero de 2011