Lista de obras - Valentina Grossi - Dominio Público Uruguay

A novel AMPK-dependent FoxO3A-SIRT3 intramitochondrial complex sensing glucose levels.

artículo científico publicado en 2013

A rare MSH2 mutation causes defective binding to hMSH6, normal hMSH2 staining, and loss of hMSH6 at advanced cancer stage

artículo científico publicado en 2014

Chasing the FOXO3: Insights into Its New Mitochondrial Lair in Colorectal Cancer Landscape

artículo científico publicado en 2019

FOXO3 on the Road to Longevity: Lessons From SNPs and Chromatin Hubs

artículo científico publicado en 2019

Gastric polyposis and desmoid tumours as a new familial adenomatous polyposis clinical variant associated with APC mutation at the extreme 3'-end

artículo científico publicado en 2019

Germline pathogenic variant in PIK3CA leading to symmetrical overgrowth with marked macrocephaly and mild global developmental delay

scientific article published on 09 July 2019

In vitro efficacy of ARQ 092, an allosteric AKT inhibitor, on primary fibroblast cells derived from patients with PIK3CA-related overgrowth spectrum (PROS).

artículo científico publicado en 2018

Integrated multi-omics characterization reveals a distinctive metabolic signature and the role of NDUFA4L2 in promoting angiogenesis, chemoresistance, and mitochondrial dysfunction in clear cell renal cell carcinoma

artículo científico publicado en 2018

Loss of STK11 expression is an early event in prostate carcinogenesis and predicts therapeutic response to targeted therapy against MAPK/p38.

artículo científico publicado en 2015

Molecular and Functional Characterization of Three Different Postzygotic Mutations in PIK3CA-Related Overgrowth Spectrum (PROS) Patients: Effects on PI3K/AKT/mTOR Signaling and Sensitivity to PIK3 Inhibitors.

artículo científico publicado en 2015

Sorafenib inhibits p38α activity in colorectal cancer cells and synergizes with the DFG-in inhibitor SB202190 to increase apoptotic response

artículo científico publicado en 2012

Targeted therapy against chemoresistant colorectal cancers: Inhibition of p38α modulates the effect of cisplatin in vitro and in vivo through the tumor suppressor FoxO3A.

artículo científico publicado en 2013

The longevity SNP rs2802292 uncovered: HSF1 activates stress-dependent expression of FOXO3 through an intronic enhancer.

artículo científico publicado en 2018

Uncoupling FoxO3A mitochondrial and nuclear functions in cancer cells undergoing metabolic stress and chemotherapy

artículo científico publicado en 2018

Updates from the Intestinal Front Line: Autophagic Weapons against Inflammation and Cancer

artículo científico

p38alpha is required for ovarian cancer cell metabolism and survival.

artículo científico publicado en 2010

p38α MAPK pathway: a key factor in colorectal cancer therapy and chemoresistance.

artículo científico publicado en 2014

Lista de obras de Valentina Grossi

A novel AMPK-dependent FoxO3A-SIRT3 intramitochondrial complex sensing glucose levels.

A rare MSH2 mutation causes defective binding to hMSH6, normal hMSH2 staining, and loss of hMSH6 at advanced cancer stage

Chasing the FOXO3: Insights into Its New Mitochondrial Lair in Colorectal Cancer Landscape

FOXO3 on the Road to Longevity: Lessons From SNPs and Chromatin Hubs

Gastric polyposis and desmoid tumours as a new familial adenomatous polyposis clinical variant associated with APC mutation at the extreme 3'-end

Germline pathogenic variant in PIK3CA leading to symmetrical overgrowth with marked macrocephaly and mild global developmental delay

In vitro efficacy of ARQ 092, an allosteric AKT inhibitor, on primary fibroblast cells derived from patients with PIK3CA-related overgrowth spectrum (PROS).

Integrated multi-omics characterization reveals a distinctive metabolic signature and the role of NDUFA4L2 in promoting angiogenesis, chemoresistance, and mitochondrial dysfunction in clear cell renal cell carcinoma

Loss of STK11 expression is an early event in prostate carcinogenesis and predicts therapeutic response to targeted therapy against MAPK/p38.

Molecular and Functional Characterization of Three Different Postzygotic Mutations in PIK3CA-Related Overgrowth Spectrum (PROS) Patients: Effects on PI3K/AKT/mTOR Signaling and Sensitivity to PIK3 Inhibitors.

Sorafenib inhibits p38α activity in colorectal cancer cells and synergizes with the DFG-in inhibitor SB202190 to increase apoptotic response

Targeted therapy against chemoresistant colorectal cancers: Inhibition of p38α modulates the effect of cisplatin in vitro and in vivo through the tumor suppressor FoxO3A.

The longevity SNP rs2802292 uncovered: HSF1 activates stress-dependent expression of FOXO3 through an intronic enhancer.

Uncoupling FoxO3A mitochondrial and nuclear functions in cancer cells undergoing metabolic stress and chemotherapy

Updates from the Intestinal Front Line: Autophagic Weapons against Inflammation and Cancer

p38alpha is required for ovarian cancer cell metabolism and survival.

p38α MAPK pathway: a key factor in colorectal cancer therapy and chemoresistance.