Lista de obras - Jaroslav Roh - Dominio Público Uruguay

1-Substituted-5-[(3,5-dinitrobenzyl)sulfanyl]-1H-tetrazoles and their isosteric analogs: A new class of selective antitubercular agents active against drug-susceptible and multidrug-resistant mycobacteria

artículo científico publicado en 2014

2,6-Dihydroxybenzaldehyde Analogues of the Iron Chelator Salicylaldehyde Isonicotinoyl Hydrazone: Increased Hydrolytic Stability and Cytoprotective Activity against Oxidative Stress

scientific article published on 05 November 2018

A UHPLC-UV-QTOF study on the stability of carfilzomib, a novel proteasome inhibitor

artículo científico publicado en 2016

Amino acid derivatives as transdermal permeation enhancers

artículo científico publicado en 2012

Azaphthalocyanines with fused triazolo rings: formation of sterically stressed constitutional isomers

artículo científico publicado en 2012

Ceramides in the Skin Lipid Membranes: Length Matters

scientific article published on 06 December 2013

Characterization of cytoprotective and toxic properties of iron chelator SIH, prochelator BSIH and their degradation products.

artículo científico publicado en 2016

Development of 2-Methoxyhuprine as Novel Lead for Alzheimer's Disease Therapy.

artículo científico publicado en 2017

Development of 3,5-Dinitrobenzylsulfanyl-1,3,4-oxadiazoles and Thiadiazoles as Selective Antitubercular Agents Active Against Replicating and Nonreplicating Mycobacterium tuberculosis

artículo científico publicado en 2016

Development of 3,5-Dinitrophenyl-Containing 1,2,4-Triazoles and Their Trifluoromethyl Analogues as Highly Efficient Antitubercular Agents Inhibiting Decaprenylphosphoryl-β-d-ribofuranose 2'-Oxidase

artículo científico publicado en 2019

Development of water-soluble 3,5-dinitrophenyl tetrazole and oxadiazole antitubercular agents.

artículo científico publicado en 2017

Different Phase Behavior and Packing of Ceramides with Long (C16) and Very Long (C24) Acyls in Model Membranes: Infrared Spectroscopy Using Deuterated Lipids

scientific article published on 21 August 2014

Enhanced Topical and Transdermal Delivery of Antineoplastic and Antiviral Acyclic Nucleoside Phosphonate cPr-PMEDAP

artículo científico publicado en 2011

Esters of terpene alcohols as highly potent, reversible, and low toxic skin penetration enhancers

artículo científico publicado en 2019

In Vitro Characterization of the Pharmacological Properties of the Anti-Cancer Chelator, Bp4eT, and Its Phase I Metabolites

artículo científico publicado en 2015

Investigation of novel dexrazoxane analogue JR-311 shows significant cardioprotective effects through topoisomerase IIbeta but not its iron chelating metabolite.

artículo científico publicado en 2017

Investigation of structure-activity relationships of dexrazoxane analogues reveals topoisomerase IIβ interaction as a prerequisite for effective protection against anthracycline cardiotoxicity

scientific article published on 06 April 2020

Metal-Cation Recognition in Water by a Tetrapyrazinoporphyrazine-Based Tweezer Receptor

artículo científico publicado en 2016

Novel SPME fibers based on a plastic support for determination of plasma protein binding of thiosemicarbazone metal chelators: a case example of DpC, an anti-cancer drug that entered clinical trials

scientific article published on 01 March 2019

Novel and potent anti-tumor and anti-metastatic di-2-pyridylketone thiosemicarbazones demonstrate marked differences in pharmacology between the first and second generation lead agents.

artículo científico publicado en 2015

Pharmacokinetics of the cardioprotective drug dexrazoxane and its active metabolite ADR-925 with focus on cardiomyocytes and the heart.

artículo científico publicado en 2017

S-substituted 3,5-dinitrophenyl 1,3,4-oxadiazole-2-thiols and tetrazole-5-thiols as highly efficient antitubercular agents

scientific article published on 21 November 2016

Scalable Synthesis of Human Ultralong Chain Ceramides

artículo científico publicado en 2015

Simultaneous determination of the novel thiosemicarbazone anti-cancer agent, Bp4eT, and its main phase I metabolites in plasma: application to a pilot pharmacokinetic study in rats

artículo científico publicado en 2013

Structure-activity relationship studies on 3,5-dinitrophenyl tetrazoles as antitubercular agents

artículo científico publicado en 2017

Tetrazole regioisomers in the development of nitro group-containing antitubercular agents

article

The Role of the Trans Double Bond in Skin Barrier Sphingolipids: Permeability and Infrared Spectroscopic Study of Model Ceramide and Dihydroceramide Membranes

scientific article published on 07 May 2014

The chemistry and biology of 6-hydroxyceramide, the youngest member of the human sphingolipid family

artículo científico publicado en 2014

Transdermal delivery and cutaneous targeting of antivirals using a penetration enhancer and lysolipid prodrugs

artículo científico publicado en 2013

UHPLC-MS/MS method for analysis of sobuzoxane, its active form ICRF-154 and metabolite EDTA-diamide and its application to bioactivation study

artículo científico publicado en 2019

Lista de obras de Jaroslav Roh

1-Substituted-5-[(3,5-dinitrobenzyl)sulfanyl]-1H-tetrazoles and their isosteric analogs: A new class of selective antitubercular agents active against drug-susceptible and multidrug-resistant mycobacteria

2,6-Dihydroxybenzaldehyde Analogues of the Iron Chelator Salicylaldehyde Isonicotinoyl Hydrazone: Increased Hydrolytic Stability and Cytoprotective Activity against Oxidative Stress

A UHPLC-UV-QTOF study on the stability of carfilzomib, a novel proteasome inhibitor

Amino acid derivatives as transdermal permeation enhancers

Azaphthalocyanines with fused triazolo rings: formation of sterically stressed constitutional isomers

Ceramides in the Skin Lipid Membranes: Length Matters

Characterization of cytoprotective and toxic properties of iron chelator SIH, prochelator BSIH and their degradation products.

Development of 2-Methoxyhuprine as Novel Lead for Alzheimer's Disease Therapy.

Development of 3,5-Dinitrobenzylsulfanyl-1,3,4-oxadiazoles and Thiadiazoles as Selective Antitubercular Agents Active Against Replicating and Nonreplicating Mycobacterium tuberculosis

Development of 3,5-Dinitrophenyl-Containing 1,2,4-Triazoles and Their Trifluoromethyl Analogues as Highly Efficient Antitubercular Agents Inhibiting Decaprenylphosphoryl-β-d-ribofuranose 2'-Oxidase

Development of water-soluble 3,5-dinitrophenyl tetrazole and oxadiazole antitubercular agents.

Different Phase Behavior and Packing of Ceramides with Long (C16) and Very Long (C24) Acyls in Model Membranes: Infrared Spectroscopy Using Deuterated Lipids

Enhanced Topical and Transdermal Delivery of Antineoplastic and Antiviral Acyclic Nucleoside Phosphonate cPr-PMEDAP

Esters of terpene alcohols as highly potent, reversible, and low toxic skin penetration enhancers

In Vitro Characterization of the Pharmacological Properties of the Anti-Cancer Chelator, Bp4eT, and Its Phase I Metabolites

Investigation of novel dexrazoxane analogue JR-311 shows significant cardioprotective effects through topoisomerase IIbeta but not its iron chelating metabolite.

Investigation of structure-activity relationships of dexrazoxane analogues reveals topoisomerase IIβ interaction as a prerequisite for effective protection against anthracycline cardiotoxicity

Metal-Cation Recognition in Water by a Tetrapyrazinoporphyrazine-Based Tweezer Receptor

Novel SPME fibers based on a plastic support for determination of plasma protein binding of thiosemicarbazone metal chelators: a case example of DpC, an anti-cancer drug that entered clinical trials

Novel and potent anti-tumor and anti-metastatic di-2-pyridylketone thiosemicarbazones demonstrate marked differences in pharmacology between the first and second generation lead agents.

Pharmacokinetics of the cardioprotective drug dexrazoxane and its active metabolite ADR-925 with focus on cardiomyocytes and the heart.

S-substituted 3,5-dinitrophenyl 1,3,4-oxadiazole-2-thiols and tetrazole-5-thiols as highly efficient antitubercular agents

Scalable Synthesis of Human Ultralong Chain Ceramides

Simultaneous determination of the novel thiosemicarbazone anti-cancer agent, Bp4eT, and its main phase I metabolites in plasma: application to a pilot pharmacokinetic study in rats

Structure-activity relationship studies on 3,5-dinitrophenyl tetrazoles as antitubercular agents

Tetrazole regioisomers in the development of nitro group-containing antitubercular agents

The Role of the Trans Double Bond in Skin Barrier Sphingolipids: Permeability and Infrared Spectroscopic Study of Model Ceramide and Dihydroceramide Membranes

The chemistry and biology of 6-hydroxyceramide, the youngest member of the human sphingolipid family

Transdermal delivery and cutaneous targeting of antivirals using a penetration enhancer and lysolipid prodrugs

UHPLC-MS/MS method for analysis of sobuzoxane, its active form ICRF-154 and metabolite EDTA-diamide and its application to bioactivation study