Lista de obras - Bao-Liang Song - Dominio Público Uruguay

A LIMA1 variant promotes low plasma LDL cholesterol and decreases intestinal cholesterol absorption

artículo científico publicado en 2018

A special issue on 'Metabolism'

artículo científico publicado en 2013

A specific cholesterol metabolic pathway is established in a subset of HCCs for tumor growth.

artículo científico publicado en 2013

AAV9-NPC1 significantly ameliorates Purkinje cell death and behavioral abnormalities in mouse NPC disease

artículo científico publicado en 2017

Ablation of gp78 in liver improves hyperlipidemia and insulin resistance by inhibiting SREBP to decrease lipid biosynthesis

artículo científico publicado en 2012

Acyl-CoA:cholesterol acyltransferases (ACATs/SOATs): Enzymes with multiple sterols as substrates and as activators.

artículo científico

Cholesterol Homeostatic Regulator SCAP-SREBP2 Integrates NLRP3 Inflammasome Activation and Cholesterol Biosynthetic Signaling in Macrophages

artículo científico publicado en 2018

Cholesterol Modification of Smoothened Is Required for Hedgehog Signaling.

artículo científico publicado en 2017

Cholesterol and fatty acids regulate cysteine ubiquitylation of ACAT2 through competitive oxidation.

artículo científico publicado en 2017

Cholesterol metabolism in cancer: mechanisms and therapeutic opportunities

artículo científico publicado en 2020

Cholesterol transport through lysosome-peroxisome membrane contacts

scientific journal article

Competitive oxidation and ubiquitylation on the evolutionarily conserved cysteine confer tissue-specific stabilization of Insig-2

artículo científico publicado en 2020

Discovery of a potent HMG-CoA reductase degrader that eliminates statin-induced reductase accumulation and lowers cholesterol

artículo científico publicado en 2018

Disruption of the ERLIN-TM6SF2-APOB complex destabilizes APOB and contributes to non-alcoholic fatty liver disease

artículo científico publicado en 2020

Effects of chrysophanol on expression of SREBPs and lipid metabolism in Huh-7 cells

artículo científico publicado en 2015

Endogenous sterol intermediates of the mevalonate pathway regulate HMGCR degradation and SREBP-2 processing

artículo científico publicado en 2019

Ezetimibe blocks the internalization of NPC1L1 and cholesterol in mouse small intestine.

artículo científico publicado en 2012

Feeding induces cholesterol biosynthesis via the mTORC1-USP20-HMGCR axis

artículo científico publicado en 2020

Flotillins play an essential role in Niemann-Pick C1-like 1-mediated cholesterol uptake.

artículo científico publicado en 2010

Forward genetic screening for regulators involved in cholesterol synthesis using validation-based insertional mutagenesis

artículo científico publicado en 2014

Gp78, a membrane-anchored ubiquitin ligase, associates with Insig-1 and couples sterol-regulated ubiquitination to degradation of HMG CoA reductase

artículo científico publicado en 2005

Gpnmb secreted from liver promotes lipogenesis in white adipose tissue and aggravates obesity and insulin resistance

artículo científico publicado en 2019

Human acyl-CoA:cholesterol acyltransferase 2 gene expression in intestinal Caco-2 cells and in hepatocellular carcinoma.

artículo científico publicado en 2006

Hypercholesterolemia risk-associated GPR146 is an orphan G-protein coupled receptor that regulates blood cholesterol levels in humans and mice

artículo científico publicado en 2020

Identification and characterization of NPC1L1 variants in Uygur and Kazakh with extreme low-density lipoprotein cholesterol.

artículo científico publicado en 2016

Identification of Cholesterol 25-Hydroxylase as a Novel Host Restriction Factor and a Part of the Primary Innate Immune Responses against Hepatitis C Virus Infection

artículo científico publicado en 2015

Inhibition of the sterol regulatory element-binding protein pathway suppresses hepatocellular carcinoma by repressing inflammation in mice

artículo científico publicado en 2016

Intracellular Cholesterol Transport by Sterol Transfer Proteins at Membrane Contact Sites

scientific article published on 08 November 2018

Isolation of mutant cells lacking Insig-1 through selection with SR-12813, an agent that stimulates degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase

artículo científico publicado en 2004

Measurement of Cholesterol Transfer from Lysosome to Peroxisome Using an In Vitro Reconstitution Assay

artículo científico publicado en 2017

Mechanisms and regulation of cholesterol homeostasis

scientific article published on 17 December 2019

Molecular characterization of the NPC1L1 variants identified from cholesterol low absorbers

artículo científico publicado en 2010

Myeloid Acat1/Soat1 KO attenuates pro-inflammatory responses in macrophages and protects against atherosclerosis in a model of advanced lesions

scientific article published on 08 September 2019

Myosin Vb controls biogenesis of post-Golgi Rab10 carriers during axon development ⬇️

artículo científico publicado el 1 de enero de 2013

Niemann-Pick C1-Like 1 and cholesterol uptake.

artículo científico publicado en 2012

Numb directs the subcellular localization of EAAT3 through binding the YxNxxF motif.

artículo científico publicado en 2016

PAQR3 modulates cholesterol homeostasis by anchoring Scap/SREBP complex to the Golgi apparatus

artículo científico publicado en 2015

PIP4K2A regulates intracellular cholesterol transport through modulating PI(4,5)P2 homeostasis.

artículo científico publicado en 2018

POST1/C12ORF49 regulates the SREBP pathway by promoting site-1 protease maturation

artículo científico publicado en 2020

Post-translational regulation of lipogenesis via AMPK-dependent phosphorylation of insulin-induced gene

scientific article published in Nature Communications

Potentiating the antitumour response of CD8(+) T cells by modulating cholesterol metabolism

artículo científico publicado en 2016

Preparation of an anti-Cdx-2 antibody for analysis of different species Cdx-2 binding to acat2 promoter

artículo científico publicado en 2003

Production of ACAT1 56-kDa isoform in human cells via trans-splicing involving the ampicillin resistance gene ⬇️

artículo científico publicado el 9 de julio de 2013

Requirement of myosin Vb.Rab11a.Rab11-FIP2 complex in cholesterol-regulated translocation of NPC1L1 to the cell surface

artículo científico publicado en 2009

Ring finger protein 145 (RNF145) is a ubiquitin ligase for sterol-induced degradation of HMG-CoA reductase.

artículo científico publicado en 2018

Routes and mechanisms of post-endosomal cholesterol trafficking: A story that never ends.

artículo científico publicado en 2017

SREBP: a novel therapeutic target ⬇️

artículo científico publicado el 1 de enero de 2013

SUMOylation of the ubiquitin ligase IDOL decreases LDL receptor levels and is reversed by SENP1

artículo científico publicado en 2020

Schnyder corneal dystrophy-associated UBIAD1 mutations cause corneal cholesterol accumulation by stabilizing HMG-CoA reductase

artículo científico publicado en 2019

TNF-alpha stimulates the ACAT1 expression in differentiating monocytes to promote the CE-laden cell formation

artículo científico publicado en 2009

Tetra-glutamic acid residues adjacent to Lys248 in HMG-CoA reductase are critical for the ubiquitination mediated by gp78 and UBE2G2.

artículo científico publicado en 2010

The GARP Complex Is Involved in Intracellular Cholesterol Transport via Targeting NPC2 to Lysosomes.

artículo científico publicado en 2017

The N-terminal domain of NPC1L1 protein binds cholesterol and plays essential roles in cholesterol uptake.

artículo científico publicado en 2011

The cholesterol absorption inhibitor ezetimibe acts by blocking the sterol-induced internalization of NPC1L1.

artículo científico publicado en 2008

The clathrin adaptor Numb regulates intestinal cholesterol absorption through dynamic interaction with NPC1L1.

artículo científico publicado en 2013

The clathrin adaptor proteins ARH, Dab2, and numb play distinct roles in Niemann-Pick C1-Like 1 versus low density lipoprotein receptor-mediated cholesterol uptake.

artículo científico publicado en 2014

The non-canonical NF-κB pathway promotes NPC2 expression and regulates intracellular cholesterol trafficking

scientific article published on 07 August 2018

The small GTPase Cdc42 interacts with Niemann-Pick C1-like 1 (NPC1L1) and controls its movement from endocytic recycling compartment to plasma membrane in a cholesterol-dependent manner

scientific journal article

Two human ACAT2 mRNA variants produced by alternative splicing and coding for novel isoenzymes.

artículo científico publicado en 2005

Ubiquitin ligases in cholesterol metabolism

artículo científico publicado en 2014

Ubiquitination of 3-hydroxy-3-methylglutaryl-CoA reductase in permeabilized cells mediated by cytosolic E1 and a putative membrane-bound ubiquitin ligase.

artículo científico publicado en 2004

Ufd1 is a cofactor of gp78 and plays a key role in cholesterol metabolism by regulating the stability of HMG-CoA reductase

artículo científico publicado en 2007

Lista de obras de Bao-Liang Song

A LIMA1 variant promotes low plasma LDL cholesterol and decreases intestinal cholesterol absorption

A special issue on 'Metabolism'

A specific cholesterol metabolic pathway is established in a subset of HCCs for tumor growth.

AAV9-NPC1 significantly ameliorates Purkinje cell death and behavioral abnormalities in mouse NPC disease

Ablation of gp78 in liver improves hyperlipidemia and insulin resistance by inhibiting SREBP to decrease lipid biosynthesis

Acyl-CoA:cholesterol acyltransferases (ACATs/SOATs): Enzymes with multiple sterols as substrates and as activators.

Cholesterol Homeostatic Regulator SCAP-SREBP2 Integrates NLRP3 Inflammasome Activation and Cholesterol Biosynthetic Signaling in Macrophages

Cholesterol Modification of Smoothened Is Required for Hedgehog Signaling.

Cholesterol and fatty acids regulate cysteine ubiquitylation of ACAT2 through competitive oxidation.

Cholesterol metabolism in cancer: mechanisms and therapeutic opportunities

Cholesterol transport through lysosome-peroxisome membrane contacts

Competitive oxidation and ubiquitylation on the evolutionarily conserved cysteine confer tissue-specific stabilization of Insig-2

Discovery of a potent HMG-CoA reductase degrader that eliminates statin-induced reductase accumulation and lowers cholesterol

Disruption of the ERLIN-TM6SF2-APOB complex destabilizes APOB and contributes to non-alcoholic fatty liver disease

Effects of chrysophanol on expression of SREBPs and lipid metabolism in Huh-7 cells

Endogenous sterol intermediates of the mevalonate pathway regulate HMGCR degradation and SREBP-2 processing

Ezetimibe blocks the internalization of NPC1L1 and cholesterol in mouse small intestine.

Feeding induces cholesterol biosynthesis via the mTORC1-USP20-HMGCR axis

Flotillins play an essential role in Niemann-Pick C1-like 1-mediated cholesterol uptake.

Forward genetic screening for regulators involved in cholesterol synthesis using validation-based insertional mutagenesis

Gp78, a membrane-anchored ubiquitin ligase, associates with Insig-1 and couples sterol-regulated ubiquitination to degradation of HMG CoA reductase

Gpnmb secreted from liver promotes lipogenesis in white adipose tissue and aggravates obesity and insulin resistance

Human acyl-CoA:cholesterol acyltransferase 2 gene expression in intestinal Caco-2 cells and in hepatocellular carcinoma.

Hypercholesterolemia risk-associated GPR146 is an orphan G-protein coupled receptor that regulates blood cholesterol levels in humans and mice

Identification and characterization of NPC1L1 variants in Uygur and Kazakh with extreme low-density lipoprotein cholesterol.

Identification of Cholesterol 25-Hydroxylase as a Novel Host Restriction Factor and a Part of the Primary Innate Immune Responses against Hepatitis C Virus Infection

Inhibition of the sterol regulatory element-binding protein pathway suppresses hepatocellular carcinoma by repressing inflammation in mice

Intracellular Cholesterol Transport by Sterol Transfer Proteins at Membrane Contact Sites

Isolation of mutant cells lacking Insig-1 through selection with SR-12813, an agent that stimulates degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase

Measurement of Cholesterol Transfer from Lysosome to Peroxisome Using an In Vitro Reconstitution Assay

Mechanisms and regulation of cholesterol homeostasis

Molecular characterization of the NPC1L1 variants identified from cholesterol low absorbers

Myeloid Acat1/Soat1 KO attenuates pro-inflammatory responses in macrophages and protects against atherosclerosis in a model of advanced lesions

Myosin Vb controls biogenesis of post-Golgi Rab10 carriers during axon development ⬇️

Niemann-Pick C1-Like 1 and cholesterol uptake.

Numb directs the subcellular localization of EAAT3 through binding the YxNxxF motif.

PAQR3 modulates cholesterol homeostasis by anchoring Scap/SREBP complex to the Golgi apparatus

PIP4K2A regulates intracellular cholesterol transport through modulating PI(4,5)P2 homeostasis.

POST1/C12ORF49 regulates the SREBP pathway by promoting site-1 protease maturation

Post-translational regulation of lipogenesis via AMPK-dependent phosphorylation of insulin-induced gene

Potentiating the antitumour response of CD8(+) T cells by modulating cholesterol metabolism

Preparation of an anti-Cdx-2 antibody for analysis of different species Cdx-2 binding to acat2 promoter

Production of ACAT1 56-kDa isoform in human cells via trans-splicing involving the ampicillin resistance gene ⬇️

Requirement of myosin Vb.Rab11a.Rab11-FIP2 complex in cholesterol-regulated translocation of NPC1L1 to the cell surface

Ring finger protein 145 (RNF145) is a ubiquitin ligase for sterol-induced degradation of HMG-CoA reductase.

Routes and mechanisms of post-endosomal cholesterol trafficking: A story that never ends.

SREBP: a novel therapeutic target ⬇️

SUMOylation of the ubiquitin ligase IDOL decreases LDL receptor levels and is reversed by SENP1

Schnyder corneal dystrophy-associated UBIAD1 mutations cause corneal cholesterol accumulation by stabilizing HMG-CoA reductase

TNF-alpha stimulates the ACAT1 expression in differentiating monocytes to promote the CE-laden cell formation

Tetra-glutamic acid residues adjacent to Lys248 in HMG-CoA reductase are critical for the ubiquitination mediated by gp78 and UBE2G2.

The GARP Complex Is Involved in Intracellular Cholesterol Transport via Targeting NPC2 to Lysosomes.

The N-terminal domain of NPC1L1 protein binds cholesterol and plays essential roles in cholesterol uptake.

The cholesterol absorption inhibitor ezetimibe acts by blocking the sterol-induced internalization of NPC1L1.

The clathrin adaptor Numb regulates intestinal cholesterol absorption through dynamic interaction with NPC1L1.

The clathrin adaptor proteins ARH, Dab2, and numb play distinct roles in Niemann-Pick C1-Like 1 versus low density lipoprotein receptor-mediated cholesterol uptake.

The non-canonical NF-κB pathway promotes NPC2 expression and regulates intracellular cholesterol trafficking

The small GTPase Cdc42 interacts with Niemann-Pick C1-like 1 (NPC1L1) and controls its movement from endocytic recycling compartment to plasma membrane in a cholesterol-dependent manner

Two human ACAT2 mRNA variants produced by alternative splicing and coding for novel isoenzymes.

Ubiquitin ligases in cholesterol metabolism

Ubiquitination of 3-hydroxy-3-methylglutaryl-CoA reductase in permeabilized cells mediated by cytosolic E1 and a putative membrane-bound ubiquitin ligase.

Ufd1 is a cofactor of gp78 and plays a key role in cholesterol metabolism by regulating the stability of HMG-CoA reductase