Lista de obras -

AML-associated Flt3 kinase domain mutations show signal transduction differences compared with Flt3 ITD mutations.

artículo científico publicado en 2005

Activating c-KIT mutations confer oncogenic cooperativity and rescue RUNX1/ETO-induced DNA damage and apoptosis in human primary CD34+ hematopoietic progenitors.

artículo científico publicado en 2014

Adaptor protein Lnk binds to PDGF receptor and inhibits PDGF-dependent signaling

artículo científico publicado en 2011

Adaptor protein Lnk inhibits c-Fms-mediated macrophage function

artículo científico publicado en 2010

Addition of sorafenib versus placebo to standard therapy in patients aged 60 years or younger with newly diagnosed acute myeloid leukaemia (SORAML): a multicentre, phase 2, randomised controlled trial

artículo científico publicado en 2015

Adjuvant therapy for resectable high-risk soft tissue sarcoma: feasibility and efficacy of a sandwich chemoradiotherapy strategy

artículo científico publicado en 2011

Biglycan is a new high-affinity ligand for CD14 in macrophages

artículo científico publicado en 2018

Clinical Impact of Colonization with Multidrug-Resistant Organisms on Outcome after Autologous Stem Cell Transplantation: A Retrospective Single-Center Study.

artículo científico publicado en 2017

Comparative proteomics reveals a diagnostic signature for pulmonary head-and-neck cancer metastasis

scientific article published on 01 September 2018

Conservation of structure, function and inhibitor binding in UNC-51-like kinase 1 and 2 (ULK1/2)

scientific article published on 12 March 2019

Constitutive activation of Akt by Flt3 internal tandem duplications is necessary for increased survival, proliferation, and myeloid transformation.

artículo científico publicado en 2005

Curing of chloroquine-resistant malaria with clindamycin.

artículo científico publicado en 1993

Dabrafenib in patients with recurrent, BRAF V600E mutated malignant glioma and leptomeningeal disease.

artículo científico publicado en 2017

Donor cell leukemia: evidence for multiple preleukemic clones and parallel long term clonal evolution in donor and recipient

artículo científico publicado en 2017

Drug sensitivity of Plasmodium falciparum in Gabon. Activity correlations between various antimalarials.

artículo científico publicado en 1994

E3 ligase-defective Cbl mutants lead to a generalized mastocytosis and myeloproliferative disease.

artículo científico publicado en 2009

Effect of paracetamol on parasite clearance time in Plasmodium falciparum malaria.

artículo científico publicado en 1997

Estrogen receptor α regulates non-canonical autophagy that provides stress resistance to neuroblastoma and breast cancer cells and involves BAG3 function

artículo científico publicado en 2015

Feasibility of azacitidine added to standard chemotherapy in older patients with acute myeloid leukemia--a randomised SAL pilot study

artículo científico publicado en 2012

Flt3 tandem duplication mutations cooperate with Wnt signaling in leukemic signal transduction.

artículo científico publicado en 2005

Flt3-dependent transformation by inactivating c-Cbl mutations in AML

artículo científico publicado en 2007

Hemolysis is associated with low reticulocyte production index and predicts blood transfusion in severe malarial anemia

artículo científico publicado en 2010

IT behind a platform for Translational Cancer Research - concept and objectives.

artículo científico publicado en 2012

Improved Outcomes With Retinoic Acid and Arsenic Trioxide Compared With Retinoic Acid and Chemotherapy in Non-High-Risk Acute Promyelocytic Leukemia: Final Results of the Randomized Italian-German APL0406 Trial

artículo científico publicado en 2016

Innovating the outreach of comprehensive cancer centers

artículo científico publicado en 2019

Interferon-γ impairs proliferation of hematopoietic stem cells in mice

artículo científico publicado en 2013

Long-term results of all-trans retinoic acid and arsenic trioxide in non-high-risk acute promyelocytic leukemia: update of the APL0406 Italian-German randomized trial

artículo científico publicado en 2019

Loss of p14ARF in tumor cells facilitates replication of the adenovirus mutant dl1520 (ONYX-015).

artículo científico publicado en 2000

Loss of the selective autophagy receptor p62 impairs murine myeloid leukemia progression and mitophagy

artículo científico publicado en 2018

Malaria epidemiology in the province of Moyen Ogoov, Gabon.

artículo científico publicado en 1995

Minimized combinatorial CRISPR screens identify genetic interactions in autophagy

artículo científico publicado en 2021

Mutations of growth factor receptor Flt3 in acute myeloid leukemia: transformation of myeloid cells by Ras-dependent and Ras-independent mechanisms

artículo científico publicado en 2002

New method to quantify erythrophagocytosis by autologous monocytes.

artículo científico publicado en 2007

Oncolytic viruses for the treatment of cancer: current strategies and clinical trials.

artículo científico publicado en 2004

Prediction of accelerated cure in Plasmodium falciparum malaria by the elevated capacity of tumor necrosis factor production.

artículo científico publicado en 1995

Protein kinase C-mediated phosphorylation of the leukemia-associated HOXA9 protein impairs its DNA binding ability and induces myeloid differentiation.

artículo científico publicado en 2004

RGS2 is an important target gene of Flt3-ITD mutations in AML and functions in myeloid differentiation and leukemic transformation.

artículo científico publicado en 2004

Retinoic acid and arsenic trioxide for acute promyelocytic leukemia

artículo científico publicado en 2013

SOCS1 function in BCR-ABL mediated myeloproliferative disease is dependent on the cytokine environment

artículo científico publicado en 2017

Selective Autophagy in Normal and Malignant Hematopoiesis

scientific article published on 28 June 2019

Sorafenib Maintenance After Allogeneic Hematopoietic Stem Cell Transplantation for Acute Myeloid Leukemia With FLT3-Internal Tandem Duplication Mutation (SORMAIN)

artículo científico publicado en 2020

Sorafenib in combination with intensive chemotherapy in elderly patients with acute myeloid leukemia: results from a randomized, placebo-controlled trial

artículo científico publicado en 2013

Successful treatment of AIDS-associated, primary CNS lymphoma with rituximab- and methotrexate-based chemotherapy and autologous stem cell transplantation.

artículo científico publicado en 2014

Survey and analysis of the efficacy and prescription pattern of sorafenib in patients with acute myeloid leukemia

artículo científico publicado en 2011

The Phosphatases STS1 and STS2 Regulate Hematopoietic Stem and Progenitor Cell Fitness.

artículo científico publicado en 2015

The dual role of tumor necrosis factor (TNF) during a malarial attack

artículo científico publicado en 1997

Topical transforming growth factor-beta3 in the prevention or alleviation of chemotherapy-induced oral mucositis in patients with lymphomas or solid tumors

scientific article published on 01 July 2001

Ubiquitination and selective autophagy

artículo científico publicado en 2012

Lista de obras de

AML-associated Flt3 kinase domain mutations show signal transduction differences compared with Flt3 ITD mutations.

Activating c-KIT mutations confer oncogenic cooperativity and rescue RUNX1/ETO-induced DNA damage and apoptosis in human primary CD34+ hematopoietic progenitors.

Adaptor protein Lnk binds to PDGF receptor and inhibits PDGF-dependent signaling

Adaptor protein Lnk inhibits c-Fms-mediated macrophage function

Addition of sorafenib versus placebo to standard therapy in patients aged 60 years or younger with newly diagnosed acute myeloid leukaemia (SORAML): a multicentre, phase 2, randomised controlled trial

Adjuvant therapy for resectable high-risk soft tissue sarcoma: feasibility and efficacy of a sandwich chemoradiotherapy strategy

Biglycan is a new high-affinity ligand for CD14 in macrophages

Clinical Impact of Colonization with Multidrug-Resistant Organisms on Outcome after Autologous Stem Cell Transplantation: A Retrospective Single-Center Study.

Comparative proteomics reveals a diagnostic signature for pulmonary head-and-neck cancer metastasis

Conservation of structure, function and inhibitor binding in UNC-51-like kinase 1 and 2 (ULK1/2)

Constitutive activation of Akt by Flt3 internal tandem duplications is necessary for increased survival, proliferation, and myeloid transformation.

Curing of chloroquine-resistant malaria with clindamycin.

Dabrafenib in patients with recurrent, BRAF V600E mutated malignant glioma and leptomeningeal disease.

Donor cell leukemia: evidence for multiple preleukemic clones and parallel long term clonal evolution in donor and recipient

Drug sensitivity of Plasmodium falciparum in Gabon. Activity correlations between various antimalarials.

E3 ligase-defective Cbl mutants lead to a generalized mastocytosis and myeloproliferative disease.

Effect of paracetamol on parasite clearance time in Plasmodium falciparum malaria.

Estrogen receptor α regulates non-canonical autophagy that provides stress resistance to neuroblastoma and breast cancer cells and involves BAG3 function

Feasibility of azacitidine added to standard chemotherapy in older patients with acute myeloid leukemia--a randomised SAL pilot study

Flt3 tandem duplication mutations cooperate with Wnt signaling in leukemic signal transduction.

Flt3-dependent transformation by inactivating c-Cbl mutations in AML

Hemolysis is associated with low reticulocyte production index and predicts blood transfusion in severe malarial anemia

IT behind a platform for Translational Cancer Research - concept and objectives.

Improved Outcomes With Retinoic Acid and Arsenic Trioxide Compared With Retinoic Acid and Chemotherapy in Non-High-Risk Acute Promyelocytic Leukemia: Final Results of the Randomized Italian-German APL0406 Trial

Innovating the outreach of comprehensive cancer centers

Interferon-γ impairs proliferation of hematopoietic stem cells in mice

Long-term results of all-trans retinoic acid and arsenic trioxide in non-high-risk acute promyelocytic leukemia: update of the APL0406 Italian-German randomized trial

Loss of p14ARF in tumor cells facilitates replication of the adenovirus mutant dl1520 (ONYX-015).

Loss of the selective autophagy receptor p62 impairs murine myeloid leukemia progression and mitophagy

Malaria epidemiology in the province of Moyen Ogoov, Gabon.

Minimized combinatorial CRISPR screens identify genetic interactions in autophagy

Mutations of growth factor receptor Flt3 in acute myeloid leukemia: transformation of myeloid cells by Ras-dependent and Ras-independent mechanisms

New method to quantify erythrophagocytosis by autologous monocytes.

Oncolytic viruses for the treatment of cancer: current strategies and clinical trials.

Prediction of accelerated cure in Plasmodium falciparum malaria by the elevated capacity of tumor necrosis factor production.

Protein kinase C-mediated phosphorylation of the leukemia-associated HOXA9 protein impairs its DNA binding ability and induces myeloid differentiation.

RGS2 is an important target gene of Flt3-ITD mutations in AML and functions in myeloid differentiation and leukemic transformation.

Retinoic acid and arsenic trioxide for acute promyelocytic leukemia

SOCS1 function in BCR-ABL mediated myeloproliferative disease is dependent on the cytokine environment

Selective Autophagy in Normal and Malignant Hematopoiesis

Sorafenib Maintenance After Allogeneic Hematopoietic Stem Cell Transplantation for Acute Myeloid Leukemia With FLT3-Internal Tandem Duplication Mutation (SORMAIN)

Sorafenib in combination with intensive chemotherapy in elderly patients with acute myeloid leukemia: results from a randomized, placebo-controlled trial

Successful treatment of AIDS-associated, primary CNS lymphoma with rituximab- and methotrexate-based chemotherapy and autologous stem cell transplantation.

Survey and analysis of the efficacy and prescription pattern of sorafenib in patients with acute myeloid leukemia

The Phosphatases STS1 and STS2 Regulate Hematopoietic Stem and Progenitor Cell Fitness.

The dual role of tumor necrosis factor (TNF) during a malarial attack

Topical transforming growth factor-beta3 in the prevention or alleviation of chemotherapy-induced oral mucositis in patients with lymphomas or solid tumors

Ubiquitination and selective autophagy