Lista de obras - Petr Dzubak - Dominio Público Uruguay

2-Substituted 6-(Het)aryl-7-deazapurine Ribonucleosides: Synthesis, Inhibition of Adenosine Kinases, and Antimycobacterial Activity.

artículo científico publicado en 2015

7-(2-Thienyl)-7-Deazaadenosine (AB61), a New Potent Nucleoside Cytostatic with a Complex Mode of Action.

artículo científico publicado en 2016

Alcohol-abuse drug disulfiram targets cancer via p97 segregase adaptor NPL4.

artículo científico publicado en 2017

Aurora kinase inhibitors: progress towards the clinic

artículo científico publicado en 2012

Bioavailability and structural study of 20-hydroxyecdysone complexes with cyclodextrins

scientific article published on 17 November 2018

Biodegradable system for drug delivery of hydrolytically labile azanucleoside drugs.

artículo científico publicado en 2016

Caffeine-hydrazones as anticancer agents with pronounced selectivity toward T-lymphoblastic leukaemia cells

artículo científico publicado en 2015

Cancer cell response to anthracyclines effects: mysteries of the hidden proteins associated with these drugs

artículo científico publicado en 2012

Cell-based DNA demethylation detection system for screening of epigenetic drugs in 2D, 3D, and xenograft models.

artículo científico publicado en 2016

Cellular effects of the microtubule-targeting agent peloruside A in hypoxia-conditioned colorectal carcinoma cells.

artículo científico publicado en 2017

Correction to "Synthesis and Cytotoxic and Antiviral Profiling of Pyrrolo- and Furo-Fused 7-Deazapurine Ribonucleosides"

artículo científico publicado en 2019

Cytotoxic conjugates of betulinic acid and substituted triazoles prepared by Huisgen Cycloaddition from 30-azidoderivatives

artículo científico publicado en 2017

Cytotoxic heterocyclic triterpenoids derived from betulin and betulinic acid.

artículo científico publicado en 2012

Effects of Ginger Phenylpropanoids and Quercetin on Nrf2-ARE Pathway in Human BJ Fibroblasts and HaCaT Keratinocytes

artículo científico publicado en 2016

Estradiol dimer inhibits tubulin polymerization and microtubule dynamics

artículo científico publicado en 2018

Evaporation-reducing Culture Condition Increases the Reproducibility of Multicellular Spheroid Formation in Microtiter Plates

artículo científico publicado en 2017

Fluorinated derivatives of 2-phenyl-3-hydroxy-4(1H)-quinolinone as tubulin polymerization inhibitors

artículo científico publicado en 2020

Lupane and 18α-oleanane derivatives substituted in the position 2, their cytotoxicity and influence on cancer cells.

artículo científico publicado en 2016

Mass Spectrometry Amyloid Typing Is Reproducible across Multiple Organ Sites

artículo científico publicado en 2019

Metallacarborane Sulfamides: Unconventional, Specific, and Highly Selective Inhibitors of Carbonic Anhydrase IX

artículo científico publicado en 2019

Microtubule affinity-regulating kinases are potential druggable targets for Alzheimer's disease

artículo científico publicado en 2017

N-Benzyl Substitution of Polyhydroxypyrrolidines: The Way to Selective Inhibitors of Golgi α-Mannosidase II.

artículo científico publicado en 2018

New derivatives of silybin and 2,3-dehydrosilybin and their cytotoxic and P-glycoprotein modulatory activity.

artículo científico publicado en 2006

Optimization of the Synthesis of Flavone-Amino Acid and Flavone-Dipeptide Hybrids via Buchwald-Hartwig Reaction.

artículo científico publicado en 2017

Pharmacological activities of natural triterpenoids and their therapeutic implications.

artículo científico publicado en 2006

Preparation of Conjugates of Cytotoxic Lupane Triterpenes with Biotin.

artículo científico publicado en 2015

Protein fingerprints of anti-cancer effects of cyclin-dependent kinase inhibition: identification of candidate biomarkers using 2-D liquid phase separation coupled to mass spectrometry.

artículo científico publicado en 2005

Proteomic profiling reveals DNA damage, nucleolar and ribosomal stress are the main responses to oxaliplatin treatment in cancer cells.

artículo científico publicado en 2017

Reproducibility of Uniform Spheroid Formation in 384-Well Plates: The Effect of Medium Evaporation

scientific article published on 25 May 2016

Role of Salmonella Typhi Vi Antigen and Secretory Systems on Immune Response

artículo científico publicado en 2016

Striking antitumor activity of a methinium system with incorporated quinoxaline unit obtained by spontaneous cyclization

artículo científico publicado en 2015

Sugar modified pyrimido[4,5-]indole nucleosides: synthesis and antiviral activity

artículo científico publicado en 2017

Sulfonamido carboranes as highly selective inhibitors of cancer-specific carbonic anhydrase IX

scientific article published on 18 May 2020

Synthesis and Biological Profiling of Pyrazolo-fused 7-Deazapurine Nucleosides

artículo científico publicado en 2020

Synthesis and Cytostatic and Antiviral Profiling of Thieno-Fused 7-Deazapurine Ribonucleosides.

artículo científico publicado en 2017

Synthesis and Cytotoxic Activity of Triterpenoid Thiazoles Derived from Allobetulin, Methyl Betulonate, Methyl Oleanonate, and Oleanonic Acid

artículo científico publicado en 2017

Synthesis and Cytotoxic and Antiviral Activity Profiling of All-Four Isomeric Series of Pyrido-Fused 7-Deazapurine Ribonucleosides

scientific article published on 10 April 2020

Synthesis and Cytotoxic and Antiviral Profiling of Pyrrolo- and Furo-fused 7-Deazapurine Ribonucleosides

artículo científico publicado en 2018

Synthesis and biological activity evaluation of hydrazone derivatives based on a Tröger’s base skeleton

scientific article published on 23 January 2015

Synthesis and biological evaluation of cis-restrained carbocyclic combretastatin A-4 analogs: Influence of the ring size and saturation on cytotoxic properties

artículo científico publicado en 2019

Synthesis and biological profiling of 6- or 7-(het)aryl-7-deazapurine 4'-C-methylribonucleosides.

artículo científico publicado en 2015

Synthesis of cytotoxic 2,2-difluoroderivatives of dihydrobetulinic acid and allobetulin and study of their impact on cancer cells.

artículo científico publicado en 2015

Synthesis, Photophysical Properties and Biological Profiling of Benzothieno-Fused 7-Deazapurine Ribonucleosides

scientific article published on 20 May 2020

Synthetic approach for rapid preparation of BODIPY conjugates and their use in imaging of cellular drug uptake and distribution.

artículo científico publicado en 2018

TLR 7/8 Ligand, S28463, Suppresses Ascaris Suum Induced Allergic Asthma in Nonhuman Primates

artículo científico

The dual role of asporin in breast cancer progression

scientific article published on 07 July 2016

The natural cytokinin 2OH3MeOBAR induces cell death by a mechanism that is different from that of the "classical" cytokinin ribosides

artículo científico publicado en 2017

Trilobolide-steroid hybrids: Synthesis, cytotoxic and antimycobacterial activity.

artículo científico

Triterpenic azines, a new class of compounds with selective cytotoxicity to leukemia cells CCRF-CEM.

artículo científico publicado en 2018

Two novel mutations (p.(Ser160Pro) and p.(Arg472Cys)) causing glucose-6-phosphate isomerase deficiency are associated with erythroid dysplasia and inappropriately suppressed hepcidin.

artículo científico publicado en 2017

[Tumor cells transfer between the patient and laboratory animal as a basic methodological approach to the study of cancerogenesis and identification of biomarkers]

Lista de obras de Petr Dzubak

2-Substituted 6-(Het)aryl-7-deazapurine Ribonucleosides: Synthesis, Inhibition of Adenosine Kinases, and Antimycobacterial Activity.

7-(2-Thienyl)-7-Deazaadenosine (AB61), a New Potent Nucleoside Cytostatic with a Complex Mode of Action.

Alcohol-abuse drug disulfiram targets cancer via p97 segregase adaptor NPL4.

Aurora kinase inhibitors: progress towards the clinic

Bioavailability and structural study of 20-hydroxyecdysone complexes with cyclodextrins

Biodegradable system for drug delivery of hydrolytically labile azanucleoside drugs.

Caffeine-hydrazones as anticancer agents with pronounced selectivity toward T-lymphoblastic leukaemia cells

Cancer cell response to anthracyclines effects: mysteries of the hidden proteins associated with these drugs

Cell-based DNA demethylation detection system for screening of epigenetic drugs in 2D, 3D, and xenograft models.

Cellular effects of the microtubule-targeting agent peloruside A in hypoxia-conditioned colorectal carcinoma cells.

Correction to "Synthesis and Cytotoxic and Antiviral Profiling of Pyrrolo- and Furo-Fused 7-Deazapurine Ribonucleosides"

Cytotoxic conjugates of betulinic acid and substituted triazoles prepared by Huisgen Cycloaddition from 30-azidoderivatives

Cytotoxic heterocyclic triterpenoids derived from betulin and betulinic acid.

Effects of Ginger Phenylpropanoids and Quercetin on Nrf2-ARE Pathway in Human BJ Fibroblasts and HaCaT Keratinocytes

Estradiol dimer inhibits tubulin polymerization and microtubule dynamics

Evaporation-reducing Culture Condition Increases the Reproducibility of Multicellular Spheroid Formation in Microtiter Plates

Fluorinated derivatives of 2-phenyl-3-hydroxy-4(1H)-quinolinone as tubulin polymerization inhibitors

Lupane and 18α-oleanane derivatives substituted in the position 2, their cytotoxicity and influence on cancer cells.

Mass Spectrometry Amyloid Typing Is Reproducible across Multiple Organ Sites

Metallacarborane Sulfamides: Unconventional, Specific, and Highly Selective Inhibitors of Carbonic Anhydrase IX

Microtubule affinity-regulating kinases are potential druggable targets for Alzheimer's disease

N-Benzyl Substitution of Polyhydroxypyrrolidines: The Way to Selective Inhibitors of Golgi α-Mannosidase II.

New derivatives of silybin and 2,3-dehydrosilybin and their cytotoxic and P-glycoprotein modulatory activity.

Optimization of the Synthesis of Flavone-Amino Acid and Flavone-Dipeptide Hybrids via Buchwald-Hartwig Reaction.

Pharmacological activities of natural triterpenoids and their therapeutic implications.

Preparation of Conjugates of Cytotoxic Lupane Triterpenes with Biotin.

Protein fingerprints of anti-cancer effects of cyclin-dependent kinase inhibition: identification of candidate biomarkers using 2-D liquid phase separation coupled to mass spectrometry.

Proteomic profiling reveals DNA damage, nucleolar and ribosomal stress are the main responses to oxaliplatin treatment in cancer cells.

Reproducibility of Uniform Spheroid Formation in 384-Well Plates: The Effect of Medium Evaporation

Role of Salmonella Typhi Vi Antigen and Secretory Systems on Immune Response

Striking antitumor activity of a methinium system with incorporated quinoxaline unit obtained by spontaneous cyclization

Sugar modified pyrimido[4,5-]indole nucleosides: synthesis and antiviral activity

Sulfonamido carboranes as highly selective inhibitors of cancer-specific carbonic anhydrase IX

Synthesis and Biological Profiling of Pyrazolo-fused 7-Deazapurine Nucleosides

Synthesis and Cytostatic and Antiviral Profiling of Thieno-Fused 7-Deazapurine Ribonucleosides.

Synthesis and Cytotoxic Activity of Triterpenoid Thiazoles Derived from Allobetulin, Methyl Betulonate, Methyl Oleanonate, and Oleanonic Acid

Synthesis and Cytotoxic and Antiviral Activity Profiling of All-Four Isomeric Series of Pyrido-Fused 7-Deazapurine Ribonucleosides

Synthesis and Cytotoxic and Antiviral Profiling of Pyrrolo- and Furo-fused 7-Deazapurine Ribonucleosides

Synthesis and biological activity evaluation of hydrazone derivatives based on a Tröger’s base skeleton

Synthesis and biological evaluation of cis-restrained carbocyclic combretastatin A-4 analogs: Influence of the ring size and saturation on cytotoxic properties

Synthesis and biological profiling of 6- or 7-(het)aryl-7-deazapurine 4'-C-methylribonucleosides.

Synthesis of cytotoxic 2,2-difluoroderivatives of dihydrobetulinic acid and allobetulin and study of their impact on cancer cells.

Synthesis, Photophysical Properties and Biological Profiling of Benzothieno-Fused 7-Deazapurine Ribonucleosides

Synthetic approach for rapid preparation of BODIPY conjugates and their use in imaging of cellular drug uptake and distribution.

TLR 7/8 Ligand, S28463, Suppresses Ascaris Suum Induced Allergic Asthma in Nonhuman Primates

The dual role of asporin in breast cancer progression

The natural cytokinin 2OH3MeOBAR induces cell death by a mechanism that is different from that of the "classical" cytokinin ribosides

Trilobolide-steroid hybrids: Synthesis, cytotoxic and antimycobacterial activity.

Triterpenic azines, a new class of compounds with selective cytotoxicity to leukemia cells CCRF-CEM.

Two novel mutations (p.(Ser160Pro) and p.(Arg472Cys)) causing glucose-6-phosphate isomerase deficiency are associated with erythroid dysplasia and inappropriately suppressed hepcidin.

[Tumor cells transfer between the patient and laboratory animal as a basic methodological approach to the study of cancerogenesis and identification of biomarkers]