Lista de obras -

A disintegrin and metalloproteases: molecular scissors in angiogenesis, inflammation and atherosclerosis

artículo científico

Absence of p55 TNF receptor reduces atherosclerosis, but has no major effect on angiotensin II induced aneurysms in LDL receptor deficient mice

artículo científico publicado en 2009

Accumulation of Myeloperoxidase-Positive Neutrophils in Atherosclerotic Lesions in LDLR −/− Mice

artículo científico publicado en 2007

Afucosylated IgG characterizes enveloped viral responses and correlates with COVID-19 severity

scientific article published on 23 December 2020

Anti-inflammatory M2, but not pro-inflammatory M1 macrophages promote angiogenesis in vivo

artículo científico publicado en 2013

Antibody-Mediated Inhibition of CTLA4 Aggravates Atherosclerotic Plaque Inflammation and Progression in Hyperlipidemic Mice

artículo científico publicado en 2020

Arginase-1 deficiency regulates arginine concentrations and NOS2-mediated NO production during endotoxemia.

scientific article published on 21 January 2014

Atherosclerotic plaque destabilization: mechanisms, models, and therapeutic strategies.

artículo científico publicado en 2014

Autopsy and Histological Analysis of the Transgenic Mouse

artículo científico publicado en 2011

Autopsy and histologic analysis of the transgenic mouse

artículo científico publicado en 2003

BCG lowers plasma cholesterol levels and delays atherosclerotic lesion progression in mice.

artículo científico publicado en 2016

BMP7 activates brown adipose tissue and reduces diet-induced obesity only at subthermoneutrality

artículo científico publicado en 2013

Blocking CD40-TRAF6 signaling is a therapeutic target in obesity-associated insulin resistance

artículo científico publicado en 2014

Bone Marrow Transplantations to Study Gene Function in Hematopoietic Cells

article

Bone Marrow–Specific Deficiency of Nuclear Receptor Nur77 Enhances Atherosclerosis

scientific article published on 22 December 2011

Bone marrow p16INK4a-deficiency does not modulate obesity, glucose homeostasis or atherosclerosis development

artículo científico publicado en 2012

Bone marrow transplantations to study gene function in hematopoietic cells

article

Bone marrow-specific knock-in of a non-activatable Ikkα kinase mutant influences haematopoiesis but not atherosclerosis in Apoe-deficient mice

scientific article published on 03 February 2014

CD70 limits atherosclerosis and promotes macrophage function.

artículo científico publicado en 2016

Cannabinoid Receptor 2 Deficiency in Haematopoietic cells Aggravates Early Atherosclerosis in LDL Receptor Deficient Mice.

artículo científico publicado en 2011

Centromeric and noncentromeric ADE2-selectable fragmentation vectors for yeast artificial chromosomes in AB1380.

artículo científico publicado en 1997

Circulating CD14+CD16- classical monocytes do not associate with a vulnerable plaque phenotype, and do not predict secondary events in severe atherosclerotic patients

scientific article published on 07 January 2019

DARC matter(s) for inflammatory cells

artículo científico publicado en 2018

Dectin-1 deficiency does not affect atherosclerosis development in mice

artículo científico publicado en 2015

Deficient CD40-TRAF6 signaling in leukocytes prevents atherosclerosis by skewing the immune response toward an antiinflammatory profile

artículo científico publicado en 2010

Defining tissue- and disease-associated macrophages using a transcriptome-based classification model

Deleting myeloid IL-10 receptor signalling attenuates atherosclerosis in LDLR-/- mice by altering intestinal cholesterol fluxes

artículo científico publicado en 2016

Diet-induced obesity in mice diminishes hematopoietic stem and progenitor cells in the bone marrow

artículo científico publicado en 2016

Dietary (1-->3), (1-->4)-beta-D-glucans from oat activate nuclear factor-kappaB in intestinal leukocytes and enterocytes from mice

Distribution of macrophage polarization markers in human atherosclerosis

scientific article published on 26 September 2012

Echogenic perfluorohexane-loaded macrophages adhere in vivo to activated vascular endothelium in mice, an explorative study

artículo científico publicado en 2015

Endothelial CSN5 impairs NF-κB activation and monocyte adhesion to endothelial cells and is highly expressed in human atherosclerotic lesions

artículo científico publicado en 2013

Endothelial cell-specific NF-kappaB inhibition protects mice from atherosclerosis

artículo científico publicado en 2008

Epigenetic Regulation of Monocyte and Macrophage Function

artículo científico publicado en 2016

Epigenetic mechanisms of macrophage activation in type 2 diabetes.

artículo científico publicado en 2016

Epigenetic pathways in macrophages emerge as novel targets in atherosclerosis

artículo científico

Head-to-Head Comparison of Anti-Inflammatory Performance of Known Natural Products In Vitro

artículo científico publicado en 2016

Helminth antigens counteract a rapid high-fat diet-induced decrease in adipose tissue eosinophils.

artículo científico publicado en 2017

Hematopoietic NF- B1 deficiency results in small atherosclerotic lesions with an inflammatory phenotype

artículo científico publicado en 2003

Hematopoietic miR155 deficiency enhances atherosclerosis and decreases plaque stability in hyperlipidemic mice.

artículo científico publicado en 2012

High miR-124-3p expression identifies smoking individuals susceptible to atherosclerosis.

artículo científico publicado en 2017

High-Density Lipoproteins Exert Pro-inflammatory Effects on Macrophages via Passive Cholesterol Depletion and PKC-NF-κB/STAT1-IRF1 Signaling

artículo científico publicado en 2016

Hyaluronan Nanoparticles Selectively Target Plaque-Associated Macrophages and Improve Plaque Stability in Atherosclerosis

artículo científico publicado en 2017

Hypercholesterolemia-induced priming of hematopoietic stem and progenitor cells aggravates atherosclerosis

artículo científico publicado en 2014

IFN-γ priming of macrophages represses a part of the inflammatory program and attenuates neutrophil recruitment.

artículo científico publicado en 2015

Immune Modulation of Brown(ing) Adipose Tissue in Obesity.

artículo científico publicado en 2016

Impact of cholesterol on proinflammatory monocyte production by the bone marrow

artículo científico publicado en 2021

Impaired microbial killing by neutrophils from patients with protein kinase C delta deficiency

artículo científico publicado en 2015

In memoriam: Marten Hofker (1956–2016)

Inhibiting epigenetic enzymes to improve atherogenic macrophage functions.

artículo científico publicado en 2014

Inhibition of NF-kappaB activation in macrophages increases atherosclerosis in LDL receptor-deficient mice.

artículo científico publicado en 2003

Inhibition of atherogenesis by the COP9 signalosome subunit 5 in vivo.

artículo científico publicado en 2017

Interferon-β promotes macrophage foam cell formation by altering both cholesterol influx and efflux mechanisms.

artículo científico publicado en 2015

Interferons as Essential Modulators of Atherosclerosis

artículo científico

Lipopolysaccharide Lowers Cholesteryl Ester Transfer Protein by Activating F4/80+Clec4f+Vsig4+Ly6C- Kupffer Cell Subsets.

artículo científico publicado en 2018

Lipopolysaccharide-induced gene expression in murine macrophages is enhanced by prior exposure to oxLDL.

artículo científico publicado en 2006

Liposomal prednisolone promotes macrophage lipotoxicity in experimental atherosclerosis.

artículo científico publicado en 2016

Local delivery of polarized macrophages improves reperfusion recovery in a mouse hind limb ischemia model

artículo científico publicado en 2013

Loss of SR-A and CD36 activity reduces atherosclerotic lesion complexity without abrogating foam cell formation in hyperlipidemic mice

scientific article published on 23 October 2008

MAb therapy against the IFN-α/β receptor subunit 1 stimulates arteriogenesis in a murine hindlimb ischaemia model without enhancing atherosclerotic burden

artículo científico publicado en 2015

Macrophage ATP citrate lyase deficiency stabilizes atherosclerotic plaques

artículo científico publicado en 2020

Macrophage Heterogeneity: Relevance and Functional Implications in Atherosclerosis

artículo científico publicado en 2010

Macrophage Kdm6b controls the pro-fibrotic transcriptome signature of foam cells

artículo científico publicado en 2017

Macrophage microRNA-155 promotes cardiac hypertrophy and failure.

artículo científico publicado en 2013

Macrophage p53 controls macrophage death in atherosclerotic lesions of apolipoprotein E deficient mice.

artículo científico publicado en 2009

Macrophage polarization: the epigenetic point of view

artículo científico

Macrophage retinoblastoma deficiency leads to enhanced atherosclerosis development in ApoE-deficient mice

article

Macrophage secretory phospholipase A2 group X enhances anti-inflammatory responses, promotes lipid accumulation, and contributes to aberrant lung pathology

artículo científico publicado en 2008

Macrophage subsets in atherosclerosis as defined by single-cell technologies

artículo científico publicado en 2020

Macrophage-specific expression of mannose-binding lectin controls atherosclerosis in low-density lipoprotein receptor-deficient mice.

artículo científico publicado en 2009

Macrophage-specific overexpression of group IIa sPLA2 increases atherosclerosis and enhances collagen deposition

artículo científico publicado en 2004

Marten Hofker (1956–2016)

Metabolic Characterization of Polarized M1 and M2 Bone Marrow-derived Macrophages Using Real-time Extracellular Flux Analysis

artículo científico publicado en 2015

MiR-92a

artículo científico publicado en 2014

MicroRNA profiling identifies microRNA-155 as an adverse mediator of cardiac injury and dysfunction during acute viral myocarditis

artículo científico publicado en 2012

Microanatomy of the Human Atherosclerotic Plaque by Single-Cell Transcriptomics

scientific article published on 28 September 2020

Mitochondrial Dysfunction Prevents Repolarization of Inflammatory Macrophages.

artículo científico publicado en 2016

Modification of LDL with oxidized 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine (oxPAPC) results in a novel form of minimally modified LDL that modulates gene expression in macrophages

artículo científico publicado en 2008

Modulating liver inflammation: a crucial role for cholesterol

article published in 2008

Molecular pathways regulating macrophage polarization: implications for atherosclerosis

artículo científico

Monocyte and haematopoietic progenitor reprogramming as common mechanism underlying chronic inflammatory and cardiovascular diseases.

artículo científico publicado en 2017

Myeloid A disintegrin and metalloproteinase domain 10 deficiency modulates atherosclerotic plaque composition by shifting the balance from inflammation toward fibrosis.

artículo científico publicado en 2015

Myeloid IκBα deficiency promotes atherogenesis by enhancing leukocyte recruitment to the plaques

artículo científico publicado en 2011

Myeloid Type I Interferon Signaling Promotes Atherosclerosis by Stimulating Macrophage Recruitment to Lesions

artículo científico publicado en 2010

Myeloid interferon-γ receptor deficiency does not affect atherosclerosis in LDLR(-/-) mice.

artículo científico publicado en 2016

Myeloperoxidase: molecular mechanisms of action and their relevance to human health and disease.

artículo científico publicado en 2009

NF-κB activation is required for the transition of pulmonary inflammation to muscle atrophy

artículo científico publicado en 2012

New mouse models for lipoprotein metabolism and atherosclerosis

artículo científico publicado en 2002

Noncanonical NF-κB signaling in microvessels of atherosclerotic lesions is associated with inflammation, atheromatous plaque morphology and myocardial infarction

artículo científico publicado en 2018

Nuclear factor kappa B signaling in macrophage function and atherogenesis.

artículo científico publicado en 2005

Nuclear factor kappaB signaling in atherogenesis.

artículo científico publicado en 2005

PCSK9 monoclonal antibodies reverse the pro-inflammatory profile of monocytes in familial hypercholesterolaemia

artículo científico publicado en 2017

PKCδ is dispensible for oxLDL uptake and foam cell formation by human and murine macrophages

artículo científico publicado en 2014

Passive immunization with hypochlorite-oxLDL specific antibodies reduces plaque volume in LDL receptor-deficient mice

artículo científico publicado en 2013

Perfluorohexane-loaded macrophages as a novel ultrasound contrast agent: a feasibility study.

artículo científico publicado en 2008

Peritoneal macrophages have an impaired immune response in obesity which can be reversed by subsequent weight loss

scientific article published on 02 November 2019

Plant sterol or stanol esters retard lesion formation in LDL receptor-deficient mice independent of changes in serum plant sterols

article

Repressing the repressor: Ezh2 mediates macrophage activation

artículo científico publicado en 2018

Reprogramming macrophages to an anti-inflammatory phenotype by helminth antigens reduces murine atherosclerosis

artículo científico publicado en 2013

Role of scavenger receptor A and CD36 in diet-induced nonalcoholic steatohepatitis in hyperlipidemic mice.

artículo científico publicado en 2010

Rupture of the atherosclerotic plaque: does a good animal model exist?

artículo científico publicado en 2003

Salsalate activates brown adipose tissue in mice

artículo científico publicado en 2014

Scavenger receptor-AI-targeted iron oxide nanoparticles for in vivo MRI detection of atherosclerotic lesions

artículo científico publicado en 2013

Succinate Is an Inflammation-Induced Immunoregulatory Metabolite in Macrophages

scientific article published on 15 September 2020

Targeting CD40-Induced TRAF6 Signaling in Macrophages Reduces Atherosclerosis.

artículo científico publicado en 2018

Targeting macrophage Histone deacetylase 3 stabilizes atherosclerotic lesions.

artículo científico publicado en 2014

The IgM response to modified LDL in experimental atherosclerosis: hypochlorite-modified LDL IgM antibodies versus classical natural T15 IgM antibodies

artículo científico publicado en 2009

The class A macrophage scavenger receptor is a major pattern recognition receptor for Neisseria meningitidis which is independent of lipopolysaccharide and not required for secretory responses

artículo científico publicado en 2002

The environmental carcinogen benzo[a]pyrene induces expression of monocyte-chemoattractant protein-1 in vascular tissue: a possible role in atherogenesis

artículo científico publicado en 2007

The role of phospholipases in lipid modification and atherosclerosis

artículo científico publicado en 2005

Transcriptional and epigenetic regulation of macrophages in atherosclerosis

artículo científico publicado en 2019

Treatment with Trichuris suis soluble products during monocyte-to-macrophage differentiation reduces inflammatory responses through epigenetic remodeling.

artículo científico publicado en 2016

Tumor necrosis factor-alpha promotes atherosclerotic lesion progression in APOE*3-Leiden transgenic mice

artículo científico publicado en 2005

Type-I interferons in atherosclerosis

artículo científico publicado en 2020

Wound administration of M2-polarized macrophages does not improve murine cutaneous healing responses.

artículo científico publicado en 2014

p55 Tumour necrosis factor receptor in bone marrow-derived cells promotes atherosclerosis development in low-density lipoprotein receptor knock-out mice

article

Lista de obras de

A disintegrin and metalloproteases: molecular scissors in angiogenesis, inflammation and atherosclerosis

Absence of p55 TNF receptor reduces atherosclerosis, but has no major effect on angiotensin II induced aneurysms in LDL receptor deficient mice

Accumulation of Myeloperoxidase-Positive Neutrophils in Atherosclerotic Lesions in LDLR −/− Mice

Afucosylated IgG characterizes enveloped viral responses and correlates with COVID-19 severity

Anti-inflammatory M2, but not pro-inflammatory M1 macrophages promote angiogenesis in vivo

Antibody-Mediated Inhibition of CTLA4 Aggravates Atherosclerotic Plaque Inflammation and Progression in Hyperlipidemic Mice

Arginase-1 deficiency regulates arginine concentrations and NOS2-mediated NO production during endotoxemia.

Atherosclerotic plaque destabilization: mechanisms, models, and therapeutic strategies.

Autopsy and Histological Analysis of the Transgenic Mouse

Autopsy and histologic analysis of the transgenic mouse

BCG lowers plasma cholesterol levels and delays atherosclerotic lesion progression in mice.

BMP7 activates brown adipose tissue and reduces diet-induced obesity only at subthermoneutrality

Blocking CD40-TRAF6 signaling is a therapeutic target in obesity-associated insulin resistance

Bone Marrow Transplantations to Study Gene Function in Hematopoietic Cells

Bone Marrow–Specific Deficiency of Nuclear Receptor Nur77 Enhances Atherosclerosis

Bone marrow p16INK4a-deficiency does not modulate obesity, glucose homeostasis or atherosclerosis development

Bone marrow transplantations to study gene function in hematopoietic cells

Bone marrow-specific knock-in of a non-activatable Ikkα kinase mutant influences haematopoiesis but not atherosclerosis in Apoe-deficient mice

CD70 limits atherosclerosis and promotes macrophage function.

Cannabinoid Receptor 2 Deficiency in Haematopoietic cells Aggravates Early Atherosclerosis in LDL Receptor Deficient Mice.

Centromeric and noncentromeric ADE2-selectable fragmentation vectors for yeast artificial chromosomes in AB1380.

Circulating CD14+CD16- classical monocytes do not associate with a vulnerable plaque phenotype, and do not predict secondary events in severe atherosclerotic patients

DARC matter(s) for inflammatory cells

Dectin-1 deficiency does not affect atherosclerosis development in mice

Deficient CD40-TRAF6 signaling in leukocytes prevents atherosclerosis by skewing the immune response toward an antiinflammatory profile

Defining tissue- and disease-associated macrophages using a transcriptome-based classification model

Deleting myeloid IL-10 receptor signalling attenuates atherosclerosis in LDLR-/- mice by altering intestinal cholesterol fluxes

Diet-induced obesity in mice diminishes hematopoietic stem and progenitor cells in the bone marrow

Dietary (1-->3), (1-->4)-beta-D-glucans from oat activate nuclear factor-kappaB in intestinal leukocytes and enterocytes from mice

Distribution of macrophage polarization markers in human atherosclerosis

Echogenic perfluorohexane-loaded macrophages adhere in vivo to activated vascular endothelium in mice, an explorative study

Endothelial CSN5 impairs NF-κB activation and monocyte adhesion to endothelial cells and is highly expressed in human atherosclerotic lesions

Endothelial cell-specific NF-kappaB inhibition protects mice from atherosclerosis

Epigenetic Regulation of Monocyte and Macrophage Function

Epigenetic mechanisms of macrophage activation in type 2 diabetes.

Epigenetic pathways in macrophages emerge as novel targets in atherosclerosis

Head-to-Head Comparison of Anti-Inflammatory Performance of Known Natural Products In Vitro

Helminth antigens counteract a rapid high-fat diet-induced decrease in adipose tissue eosinophils.

Hematopoietic NF- B1 deficiency results in small atherosclerotic lesions with an inflammatory phenotype

Hematopoietic miR155 deficiency enhances atherosclerosis and decreases plaque stability in hyperlipidemic mice.

High miR-124-3p expression identifies smoking individuals susceptible to atherosclerosis.

High-Density Lipoproteins Exert Pro-inflammatory Effects on Macrophages via Passive Cholesterol Depletion and PKC-NF-κB/STAT1-IRF1 Signaling

Hyaluronan Nanoparticles Selectively Target Plaque-Associated Macrophages and Improve Plaque Stability in Atherosclerosis

Hypercholesterolemia-induced priming of hematopoietic stem and progenitor cells aggravates atherosclerosis

IFN-γ priming of macrophages represses a part of the inflammatory program and attenuates neutrophil recruitment.

Immune Modulation of Brown(ing) Adipose Tissue in Obesity.

Impact of cholesterol on proinflammatory monocyte production by the bone marrow

Impaired microbial killing by neutrophils from patients with protein kinase C delta deficiency

In memoriam: Marten Hofker (1956–2016)

Inhibiting epigenetic enzymes to improve atherogenic macrophage functions.

Inhibition of NF-kappaB activation in macrophages increases atherosclerosis in LDL receptor-deficient mice.

Inhibition of atherogenesis by the COP9 signalosome subunit 5 in vivo.

Interferon-β promotes macrophage foam cell formation by altering both cholesterol influx and efflux mechanisms.

Interferons as Essential Modulators of Atherosclerosis

Lipopolysaccharide Lowers Cholesteryl Ester Transfer Protein by Activating F4/80+Clec4f+Vsig4+Ly6C- Kupffer Cell Subsets.

Lipopolysaccharide-induced gene expression in murine macrophages is enhanced by prior exposure to oxLDL.

Liposomal prednisolone promotes macrophage lipotoxicity in experimental atherosclerosis.

Local delivery of polarized macrophages improves reperfusion recovery in a mouse hind limb ischemia model

Loss of SR-A and CD36 activity reduces atherosclerotic lesion complexity without abrogating foam cell formation in hyperlipidemic mice

MAb therapy against the IFN-α/β receptor subunit 1 stimulates arteriogenesis in a murine hindlimb ischaemia model without enhancing atherosclerotic burden

Macrophage ATP citrate lyase deficiency stabilizes atherosclerotic plaques

Macrophage Heterogeneity: Relevance and Functional Implications in Atherosclerosis

Macrophage Kdm6b controls the pro-fibrotic transcriptome signature of foam cells

Macrophage microRNA-155 promotes cardiac hypertrophy and failure.

Macrophage p53 controls macrophage death in atherosclerotic lesions of apolipoprotein E deficient mice.

Macrophage polarization: the epigenetic point of view

Macrophage retinoblastoma deficiency leads to enhanced atherosclerosis development in ApoE-deficient mice

Macrophage secretory phospholipase A2 group X enhances anti-inflammatory responses, promotes lipid accumulation, and contributes to aberrant lung pathology

Macrophage subsets in atherosclerosis as defined by single-cell technologies

Macrophage-specific expression of mannose-binding lectin controls atherosclerosis in low-density lipoprotein receptor-deficient mice.

Macrophage-specific overexpression of group IIa sPLA2 increases atherosclerosis and enhances collagen deposition

Marten Hofker (1956–2016)

Metabolic Characterization of Polarized M1 and M2 Bone Marrow-derived Macrophages Using Real-time Extracellular Flux Analysis

MiR-92a

MicroRNA profiling identifies microRNA-155 as an adverse mediator of cardiac injury and dysfunction during acute viral myocarditis

Microanatomy of the Human Atherosclerotic Plaque by Single-Cell Transcriptomics

Mitochondrial Dysfunction Prevents Repolarization of Inflammatory Macrophages.

Modification of LDL with oxidized 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine (oxPAPC) results in a novel form of minimally modified LDL that modulates gene expression in macrophages

Modulating liver inflammation: a crucial role for cholesterol