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A comparative study of the androgenic properties of progesterone and the progestins, medroxyprogesterone acetate (MPA) and norethisterone acetate (NET-A).

artículo científico publicado en 2014

A fully dissociated compound of plant origin for inflammatory gene repression

artículo científico publicado en 2005

A novel human GnRH receptor homolog gene: abundant and wide tissue distribution of the antisense transcript

artículo científico publicado en 1999

Abrogation of glucocorticoid receptor dimerization correlates with dissociated glucocorticoid behavior of compound a.

artículo científico publicado en 2009

Absence of mutations in exon 3 of the GnRH receptor in human gonadotroph adenomas

artículo científico publicado en 1997

Alanine-261 in intracellular loop III of the human gonadotropin-releasing hormone receptor is crucial for G-protein coupling and receptor internalization.

artículo científico publicado en 1998

Amplification, Sequence and Expression of the Harpin Encoding Gene of the Bacterial Canker Pathogen, Pseudomonas syringae pv. syringae Strain NV

article

Comparing the androgenic and estrogenic properties of progestins used in contraception and hormone therapy.

artículo científico publicado en 2017

Covalent labelling of histones with aurothiomalate. Gold-labelled H2A-H2B dimers assemble to octamers, which form crystalline helical tubes

scientific article published on 01 November 1986

Differential glucocorticoid receptor-mediated effects on immunomodulatory gene expression by progestin contraceptives: implications for HIV-1 pathogenesis

artículo científico

Differential metabolism of clinically-relevant progestogens in cell lines and tissue: Implications for biological mechanisms

scientific article published on 26 February 2019

Differential nuclear localisation and promoter occupancy play a role in glucocorticoid receptor ligand-specific transcriptional responses

artículo científico publicado en 2011

Differential regulation of endogenous pro-inflammatory cytokine genes by medroxyprogesterone acetate and norethisterone acetate in cell lines of the female genital tract.

artículo científico publicado en 2011

Expression of the Mouse Gonadotropin-Releasing Hormone Receptor Gene in αT3-1 Gonadotrope Cells Is Stimulated by Cyclic 3′,5′-Adenosine Monophosphate and Protein Kinase A, and Is Modulated by Steroidogenic Factor-1 and Nur77

artículo científico publicado el 1 de mayo de 2003

Genomic and nongenomic cross talk between the gonadotropin-releasing hormone receptor and glucocorticoid receptor signaling pathways

artículo científico publicado en 2009

Glucocorticoid receptor concentration and the ability to dimerize influence nuclear translocation and distribution

artículo científico publicado en 2012

Glucocorticoid receptor phosphorylation modulates transcription efficacy through GRIP-1 recruitment.

artículo científico publicado en 2010

Glucocorticoid-independent modulation of GR activity: Implications for immunotherapy

artículo científico publicado en 2016

Glucocorticoid-independent repression of tumor necrosis factor (TNF) alpha-stimulated interleukin (IL)-6 expression by the glucocorticoid receptor: a potential mechanism for protection against an excessive inflammatory response.

artículo científico publicado en 2011

HIV-1 Latency Is Maintained by the Estrogen Receptor

article

Hormonal Contraception and HIV-1 Acquisition: Biological Mechanisms

artículo científico publicado en 2018

Identification of Three Putative GnRH Receptor Subtypes in Vertebrates

artículo científico publicado en 1998

Impact of glucocorticoid receptor density on ligand-independent dimerization, cooperative ligand-binding and basal priming of transactivation: a cell culture model

artículo científico publicado en 2013

Incorporation of an additional glycosylation site enhances expression of functional human gonadotropin-releasing hormone receptor

artículo científico publicado en 1996

Inhibition of corticosteroid-binding globulin gene expression by glucocorticoids involves C/EBPβ

artículo científico publicado en 2014

Is a lower-dose, subcutaneous contraceptive injectable containing depot medroxyprogesterone acetate likely to impact women's risk of HIV?

artículo científico publicado en 2017

Ligand-dependent interaction of the dioxin receptor with target DNA.

artículo científico

Ligand-selective transactivation and transrepression via the glucocorticoid receptor: role of cofactor interaction

artículo científico publicado en 2008

Lipid raft- and protein kinase C-mediated synergism between glucocorticoid- and gonadotropin-releasing hormone signaling results in decreased cell proliferation.

artículo científico publicado en 2014

Liver cells contain constitutive DNase I-hypersensitive sites at the xenobiotic response elements 1 and 2 (XRE1 and -2) of the rat cytochrome P-450IA1 gene and a constitutive, nuclear XRE-binding factor that is distinct from the dioxin receptor

artículo científico publicado el 1 de septiembre de 1991

Medroxyprogesterone acetate differentially regulates interleukin (IL)-12 and IL-10 in a human ectocervical epithelial cell line in a glucocorticoid receptor (GR)-dependent manner

artículo científico publicado en 2014

Medroxyprogesterone acetate downregulates cytokine gene expression in mouse fibroblast cells.

artículo científico publicado en 2004

Medroxyprogesterone acetate, unlike norethisterone, increases HIV-1 replication in human peripheral blood mononuclear cells and an indicator cell line, via mechanisms involving the glucocorticoid receptor, increased CD4/CD8 ratios and CCR5 levels.

artículo científico publicado en 2018

Modulation of HIV-1 virulence via the host glucocorticoid receptor: towards further understanding the molecular mechanisms of HIV-1 pathogenesis.

artículo científico publicado en 2010

Molecular mechanisms of steroid receptor-mediated actions by synthetic progestins used in HRT and contraception.

scientific article published on 15 March 2011

Not all progestins are the same: implications for usage

artículo científico publicado en 2004

Pharmacokinetic, biologic and epidemiologic differences in MPA- and NET-based progestin-only injectable contraceptives relative to the potential impact on HIV acquisition in women

article

Progestogens used in postmenopausal hormone therapy: differences in their pharmacological properties, intracellular actions, and clinical effects

artículo científico publicado en 2012

Purification of an oligo(dG).oligo(dC)-binding sea urchin nuclear protein, suGF1: a family of G-string factors involved in gene regulation during development.

artículo científico publicado en 1994

Rat liver glucocorticoid receptor isolated by affinity chromatography is not a Mg2+- or Ca2+-dependent protein kinase

artículo científico publicado en 1986

Regulation of expression of mammalian gonadotrophin-releasing hormone receptor genes.

artículo científico publicado en 2005

Role of ligand-dependent GR phosphorylation and half-life in determination of ligand-specific transcriptional activity

artículo científico publicado en 2010

Specific protein-DNA interactions at a xenobiotic-responsive element: copurification of dioxin receptor and DNA-binding activity.

artículo científico publicado en 1989

Synthetic progestins used in HRT have different glucocorticoid agonist properties

artículo científico publicado en 2005

The Injectable Contraceptive Medroxyprogesterone Acetate Attenuates Mycobacterium tuberculosis-Specific Host Immunity Through the Glucocorticoid Receptor

scientific article published on 01 April 2019

The contraceptive medroxyprogesterone acetate, unlike norethisterone, directly increases R5 HIV-1 infection in human cervical explant tissue at physiologically relevant concentrations

article

The injectable-only contraceptive medroxyprogesterone acetate, unlike norethisterone acetate and progesterone, regulates inflammatory genes in endocervical cells via the glucocorticoid receptor

artículo científico publicado en 2014

The progestin-only contraceptive medroxyprogesterone acetate, but not norethisterone acetate, enhances HIV-1 Vpr-mediated apoptosis in human CD4+ T cells through the glucocorticoid receptor.

artículo científico publicado en 2013

The use of sulfosuccinimidyl-2-(p-azidosalicylamido)-1,3′-dithiopropionate as a crosslinking reagent to identify cell surface receptors

artículo científico publicado el 1 de febrero de 1988

Transformation in vitro and covalent modification with biotin of steroid-affinity-purified rat-liver glucocorticoid-hormone-receptor complex

artículo científico publicado en 1987

Two gonadotropin-releasing hormone receptor subtypes with distinct ligand selectivity and differential distribution in brain and pituitary in the goldfish (Carassius auratus)

scientific article published on March 1999

suGF1 binds in the major groove of its oligo(dG).oligo(dC) recognition sequence and is excluded by a positioned nucleosome core.

artículo científico publicado en 1994