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Acquisition of chemoresistance and EMT phenotype is linked with activation of the endothelin A receptor pathway in ovarian carcinoma cells.

artículo científico publicado en 2011

Beta-arrestin links endothelin A receptor to beta-catenin signaling to induce ovarian cancer cell invasion and metastasis

scholarly article

Endothelin A receptor/β-arrestin signaling to the Wnt pathway renders ovarian cancer cells resistant to chemotherapy

artículo científico publicado en 2014

Endothelin B receptor blockade inhibits dynamics of cell interactions and communications in melanoma cell progression.

artículo científico publicado en 2004

Endothelin axis induces metalloproteinase activation and invasiveness in human lymphatic endothelial cells

scientific article published on 01 August 2010

Endothelin receptor blockade inhibits molecular effectors of Kaposi's sarcoma cell invasion and tumor growth in vivo

artículo científico publicado en 2003

Endothelin receptor blockade inhibits proliferation of Kaposi's sarcoma cells

artículo científico publicado en 2001

Endothelin-1 and endothelin-3 promote invasive behavior via hypoxia-inducible factor-1alpha in human melanoma cells

scientific article published on 01 February 2007

Endothelin-1 cooperates with hypoxia to induce vascular-like structures through vascular endothelial growth factor-C, -D and -A in lymphatic endothelial cells.

artículo científico publicado en 2012

Endothelin-1 induces an angiogenic phenotype in cultured endothelial cells and stimulates neovascularization in vivo.

artículo científico publicado en 2000

Endothelin-1 induces the transactivation of vascular endothelial growth factor receptor-3 and modulates cell migration and vasculogenic mimicry in melanoma cells.

artículo científico publicado en 2012

Endothelin-1 induces vascular endothelial growth factor by increasing hypoxia-inducible factor-1alpha in ovarian carcinoma cells.

artículo científico publicado en 2002

Endothelin-1 inhibits prolyl hydroxylase domain 2 to activate hypoxia-inducible factor-1alpha in melanoma cells

artículo científico publicado en 2010

Endothelin-1 promotes epithelial-to-mesenchymal transition in human ovarian cancer cells

scientific article published on 01 December 2005

Endothelin-1 protects ovarian carcinoma cells against paclitaxel-induced apoptosis: requirement for Akt activation

artículo científico publicado en 2002

Endothelin-1 regulates hypoxia-inducible factor-1α and -2α stability through prolyl hydroxylase domain 2 inhibition in human lymphatic endothelial cells

artículo científico publicado en 2014

Endothelin-1 stimulates cyclooxygenase-2 expression in ovarian cancer cells through multiple signaling pathways: evidence for involvement of transactivation of the epidermal growth factor receptor.

artículo científico publicado en 2004

Endothelin-1 stimulates lymphatic endothelial cells and lymphatic vessels to grow and invade.

artículo científico publicado en 2009

Endothelin-1-induced prostaglandin E2-EP2, EP4 signaling regulates vascular endothelial growth factor production and ovarian carcinoma cell invasion.

artículo científico publicado en 2004

Endothelin-1/endothelin A receptor axis activates RhoA GTPase in epithelial ovarian cancer.

artículo científico publicado en 2016

Endothelin-B receptor blockade inhibits molecular effectors of melanoma cell progression.

artículo científico publicado en 2004

Green tea polyphenol epigallocatechin-3-gallate inhibits the endothelin axis and downstream signaling pathways in ovarian carcinoma

artículo científico publicado en 2006

Integrin-linked kinase functions as a downstream mediator of endothelin-1 to promote invasive behavior in ovarian carcinoma.

artículo científico publicado en 2006

Macitentan blocks endothelin-1 receptor activation required for chemoresistant ovarian cancer cell plasticity and metastasis.

artículo científico publicado en 2016

Role of endothelin-1 in neovascularization of ovarian carcinoma

artículo científico publicado en 2000

The endothelin A receptor and epidermal growth factor receptor signaling converge on β-catenin to promote ovarian cancer metastasis.

artículo científico publicado en 2012

The interplay between hypoxia, endothelial and melanoma cells regulates vascularization and cell motility through endothelin-1 and vascular endothelial growth factor.

artículo científico publicado en 2014

β-Arrestin 1 is required for endothelin-1-induced NF-κB activation in ovarian cancer cells.

artículo científico publicado en 2014

β-arrestin-1 is a nuclear transcriptional regulator of endothelin-1-induced β-catenin signaling.

artículo científico publicado en 2012