Lista de obras - Alexandra M Antunes - Dominio Público Uruguay

2'-Deoxythymidine adducts from the anti-HIV drug nevirapine.

artículo científico publicado en 2013

A Metabolomics-Inspired Strategy for the Identification of Protein Covalent Modifications

scientific article published on 31 July 2019

Amino acid adduct formation by the nevirapine metabolite, 12-hydroxynevirapine--a possible factor in nevirapine toxicity.

artículo científico publicado en 2010

Bioactivation to an aldehyde metabolite--possible role in the onset of toxicity induced by the anti-HIV drug abacavir

artículo científico publicado en 2013

Bioactivity of Isostructural Hydrogen Bonding Frameworks Built from Pipemidic Acid Metal Complexes

artículo científico publicado en 2020

Biomimetic oxidation of aromatic xenobiotics: synthesis of the phenolic metabolites from the anti-HIV drug efavirenz

artículo científico publicado en 2012

Differences in nevirapine biotransformation as a factor for its sex-dependent dimorphic profile of adverse drug reactions.

artículo científico publicado en 2013

Differentiation of isomeric C8-substituted alkylaniline adducts of guanine by electrospray ionization and tandem quadrupole ion trap mass spectrometry.

artículo científico publicado en 2003

Efavirenz biotransformation as an up-stream event of mood changes in HIV-infected patients.

artículo científico publicado en 2016

Electronic communication in linear oligo(azobenzene) radical anions

artículo científico publicado en 2013

Evidence for nevirapine bioactivation in man: Searching for the first step in the mechanism of nevirapine toxicity ⬇️

artículo científico publicado el 28 de junio de 2012

Genotoxic and Epigenotoxic Alterations in the Lung and Liver of Mice Induced by Acrylamide: A 28 Day Drinking Water Study

artículo científico publicado en 2019

Hepatocyte spheroids as a competent in vitro system for drug biotransformation studies: nevirapine as a bioactivation case study.

artículo científico publicado en 2016

High resolution mass spectrometry-based methodologies for identification of Etravirine bioactivation to reactive metabolites: In vitro and in vivo approaches

artículo científico publicado en 2018

Mass Spectrometry-Based Methodologies for Targeted and Untargeted Identification of Protein Covalent Adducts (Adductomics): Current Status and Challenges

artículo científico publicado en 2019

Mercapturate Pathway in the Tubulocentric Perspective of Diabetic Kidney Disease

scientific article published on 09 January 2019

Molecular motions in amorphous ibuprofen as studied by broadband dielectric spectroscopy.

artículo científico publicado en 2008

Monitoring abacavir bioactivation in humans: screening for an aldehyde metabolite

artículo científico publicado en 2013

Nevirapine Biotransformation Insights: An Integrated In Vitro Approach Unveils the Biocompetence and Glutathiolomic Profile of a Human Hepatocyte-Like Cell 3D Model

artículo científico publicado en 2020

Nevirapine modulation of paraoxonase-1 in the liver: An in vitro three-model approach

artículo científico publicado en 2015

New Syntheses of DNA Adducts from Methylated Anilines Present in Tobacco Smoke

artículo científico publicado en 1999

New insights into the molecular mechanisms of chemical carcinogenesis: In vivo adduction of histone H2B by a reactive metabolite of the chemical carcinogen furan.

artículo científico publicado en 2016

N‐terminal valine adduct from the anti‐HIV drug abacavir in rat haemoglobin as evidence for abacavir metabolism to a reactive aldehyde in vivo ⬇️

artículo científico publicado el 1 de noviembre de 2012

Oxidation of 2-Hydroxynevirapine, a Phenolic Metabolite of the Anti-HIV Drug Nevirapine: Evidence for an Unusual Pyridine Ring Contraction

article

Packing Interactions and Physicochemical Properties of Novel Multicomponent Crystal Forms of the Anti-Inflammatory Azelaic Acid Studied by X-ray and Solid-State NMR

Protein adducts as prospective biomarkers of nevirapine toxicity.

artículo científico publicado en 2010

Reactive aldehyde metabolites from the anti-HIV drug abacavir: amino acid adducts as possible factors in abacavir toxicity

scientific article published on 11 November 2011

Scavenging activity of aminoantipyrines against hydroxyl radical.

artículo científico publicado en 2010

Selenium-containing chrysin and quercetin derivatives: attractive scaffolds for cancer therapy.

artículo científico publicado en 2015

Severe Acute Kidney Injury and Double Tubulopathy Due to Dual Toxicity Caused by Combination Antiretroviral Therapy.

artículo científico publicado en 2018

Sex differences in hepatic and intestinal contributions to nevirapine biotransformation in rats.

artículo científico publicado en 2015

Singularities of nevirapine metabolism: from sex-dependent differences to idiosyncratic toxicity

scientific article published on 01 February 2019

Synthesis and biological activity of 6-selenocaffeine: potential modulator of chemotherapeutic drugs in breast cancer cells.

artículo científico publicado en 2013

Synthesis and characterization of DNA adducts from the HIV reverse transcriptase inhibitor nevirapine.

artículo científico publicado en 2008

Synthesis and evaluation of diaryl sulfides and diaryl selenide compounds for antitubulin and cytotoxic activity.

artículo científico publicado en 2013

Targeting Glutathione and Cystathionine β-Synthase in Ovarian Cancer Treatment by Selenium-Chrysin Polyurea Dendrimer Nanoformulation

artículo científico publicado en 2019

The first-line antiepileptic drug carbamazepine: Reaction with biologically relevant free radicals

article

The mercapturomic profile of health and non-communicable diseases

artículo científico publicado en 2019

The phenolic metabolites of the anti-HIV drug efavirenz: evidence for distinct reactivities upon oxidation with Frémy's salt

artículo científico publicado en 2013

The role of competitive binding to human serum albumin on efavirenz-warfarin interaction: a nuclear magnetic resonance study.

artículo científico publicado en 2013

Unmasking efavirenz neurotoxicity: Time matters to the underlying mechanisms.

artículo científico publicado en 2017

Lista de obras de Alexandra M Antunes

2'-Deoxythymidine adducts from the anti-HIV drug nevirapine.

A Metabolomics-Inspired Strategy for the Identification of Protein Covalent Modifications

Amino acid adduct formation by the nevirapine metabolite, 12-hydroxynevirapine--a possible factor in nevirapine toxicity.

Bioactivation to an aldehyde metabolite--possible role in the onset of toxicity induced by the anti-HIV drug abacavir

Bioactivity of Isostructural Hydrogen Bonding Frameworks Built from Pipemidic Acid Metal Complexes

Biomimetic oxidation of aromatic xenobiotics: synthesis of the phenolic metabolites from the anti-HIV drug efavirenz

Differences in nevirapine biotransformation as a factor for its sex-dependent dimorphic profile of adverse drug reactions.

Differentiation of isomeric C8-substituted alkylaniline adducts of guanine by electrospray ionization and tandem quadrupole ion trap mass spectrometry.

Efavirenz biotransformation as an up-stream event of mood changes in HIV-infected patients.

Electronic communication in linear oligo(azobenzene) radical anions

Evidence for nevirapine bioactivation in man: Searching for the first step in the mechanism of nevirapine toxicity ⬇️

Genotoxic and Epigenotoxic Alterations in the Lung and Liver of Mice Induced by Acrylamide: A 28 Day Drinking Water Study

Hepatocyte spheroids as a competent in vitro system for drug biotransformation studies: nevirapine as a bioactivation case study.

High resolution mass spectrometry-based methodologies for identification of Etravirine bioactivation to reactive metabolites: In vitro and in vivo approaches

Mass Spectrometry-Based Methodologies for Targeted and Untargeted Identification of Protein Covalent Adducts (Adductomics): Current Status and Challenges

Mercapturate Pathway in the Tubulocentric Perspective of Diabetic Kidney Disease

Molecular motions in amorphous ibuprofen as studied by broadband dielectric spectroscopy.

Monitoring abacavir bioactivation in humans: screening for an aldehyde metabolite

Nevirapine Biotransformation Insights: An Integrated In Vitro Approach Unveils the Biocompetence and Glutathiolomic Profile of a Human Hepatocyte-Like Cell 3D Model

Nevirapine modulation of paraoxonase-1 in the liver: An in vitro three-model approach

New Syntheses of DNA Adducts from Methylated Anilines Present in Tobacco Smoke

New insights into the molecular mechanisms of chemical carcinogenesis: In vivo adduction of histone H2B by a reactive metabolite of the chemical carcinogen furan.

N‐terminal valine adduct from the anti‐HIV drug abacavir in rat haemoglobin as evidence for abacavir metabolism to a reactive aldehyde in vivo ⬇️

Oxidation of 2-Hydroxynevirapine, a Phenolic Metabolite of the Anti-HIV Drug Nevirapine: Evidence for an Unusual Pyridine Ring Contraction

Packing Interactions and Physicochemical Properties of Novel Multicomponent Crystal Forms of the Anti-Inflammatory Azelaic Acid Studied by X-ray and Solid-State NMR

Protein adducts as prospective biomarkers of nevirapine toxicity.

Reactive aldehyde metabolites from the anti-HIV drug abacavir: amino acid adducts as possible factors in abacavir toxicity

Scavenging activity of aminoantipyrines against hydroxyl radical.

Selenium-containing chrysin and quercetin derivatives: attractive scaffolds for cancer therapy.

Severe Acute Kidney Injury and Double Tubulopathy Due to Dual Toxicity Caused by Combination Antiretroviral Therapy.

Sex differences in hepatic and intestinal contributions to nevirapine biotransformation in rats.

Singularities of nevirapine metabolism: from sex-dependent differences to idiosyncratic toxicity

Synthesis and biological activity of 6-selenocaffeine: potential modulator of chemotherapeutic drugs in breast cancer cells.

Synthesis and characterization of DNA adducts from the HIV reverse transcriptase inhibitor nevirapine.

Synthesis and evaluation of diaryl sulfides and diaryl selenide compounds for antitubulin and cytotoxic activity.

Targeting Glutathione and Cystathionine β-Synthase in Ovarian Cancer Treatment by Selenium-Chrysin Polyurea Dendrimer Nanoformulation

The first-line antiepileptic drug carbamazepine: Reaction with biologically relevant free radicals

The mercapturomic profile of health and non-communicable diseases

The phenolic metabolites of the anti-HIV drug efavirenz: evidence for distinct reactivities upon oxidation with Frémy's salt

The role of competitive binding to human serum albumin on efavirenz-warfarin interaction: a nuclear magnetic resonance study.

Unmasking efavirenz neurotoxicity: Time matters to the underlying mechanisms.