Lista de obras - Guillaume Robert - Dominio Público Uruguay

A New Hydroxylated Nonaprenylhydroquinone from the Mediterranean Marine Sponge Sarcotragus spinosulus ⬇️

artículo científico publicado el 7 de julio de 2011

A new posttranslational regulation of REDD1/DDIT4 through cleavage by caspase 3 modifies its cellular function

artículo científico publicado en 2014

ATP-competitive Plk1 inhibitors induce caspase 3-mediated Plk1 cleavage and activation in hematopoietic cell lines.

artículo científico publicado en 2017

Acadesine kills chronic myelogenous leukemia (CML) cells through PKC-dependent induction of autophagic cell death

artículo científico publicado en 2009

All tyrosine kinase inhibitor-resistant chronic myelogenous cells are highly sensitive to Ponatinib ⬇️

artículo científico publicado el 1 de diciembre de 2012

An miRNA-DNMT1 Axis Is Involved in Azacitidine Resistance and Predicts Survival in Higher-Risk Myelodysplastic Syndrome and Low Blast Count Acute Myeloid Leukemia

artículo científico publicado en 2016

Autophagy is required for CSF-1-induced macrophagic differentiation and acquisition of phagocytic functions.

artículo científico publicado en 2012

Azacitidine resistance caused by LAMP2 deficiency: a therapeutic window for the use of autophagy inhibitors in MDS/AML patients?

scientific article published on 01 March 2019

Azacitidine-resistant SKM1 myeloid cells are defective for AZA-induced mitochondrial apoptosis and autophagy.

artículo científico publicado en 2011

BCL-B (BCL2L10) is overexpressed in patients suffering from multiple myeloma (MM) and drives an MM-like disease in transgenic mice

artículo científico publicado en 2016

BCL2L10 positive cells in bone marrow are an independent prognostic factor of azacitidine outcome in myelodysplastic syndrome and acute myeloid leukemia

artículo científico publicado en 2017

Caspase 1/11 Deficiency or Pharmacological Inhibition Mitigates Psoriasis-Like Phenotype in Mice

artículo científico publicado en 2018

Differentiation inducing factor 3 mediates its anti-leukemic effect through ROS-dependent DRP1-mediated mitochondrial fission and induction of caspase-independent cell death

artículo científico publicado en 2016

Dual role of Sp3 transcription factor as an inducer of apoptosis and a marker of tumour aggressiveness

artículo científico publicado en 2009

FeCl3-promoted and ultrasound-assisted synthesis of resveratrol O-derived glycoside analogs.

artículo científico publicado en 2014

HGF induces fibronectin matrix synthesis in melanoma cells through MAP kinase-dependent signaling pathway and induction of Egr-1.

artículo científico publicado en 2005

IL-34 and CSF-1 display an equivalent macrophage differentiation ability but a different polarization potential.

artículo científico publicado en 2018

Imatinib triggers mesenchymal-like conversion of CML cells associated with increased aggressiveness.

artículo científico publicado en 2012

Implication and Regulation of AMPK during Physiological and Pathological Myeloid Differentiation

scientific article published on 30 September 2018

In Vitro and in Vivo Evaluation of Fully Substituted (5-(3-Ethoxy-3-oxopropynyl)-4-(ethoxycarbonyl)-1,2,3-triazolyl-glycosides as Original Nucleoside Analogues to Circumvent Resistance in Myeloid Malignancies

artículo científico publicado en 2017

LAMP2 expression dictates azacytidine response and prognosis in MDS/AML

artículo científico publicado en 2019

Limbic versus cognitive target for deep brain stimulation in treatment-resistant depression: accumbens more promising than caudate.

artículo científico publicado en 2014

Low-dose vemurafenib induces complete remission in a case of hairy-cell leukemia with a V600E mutation.

artículo científico publicado en 2013

Mechanism of action of the multikinase inhibitor Foretinib.

artículo científico publicado en 2011

Mechanisms of AXL overexpression and function in Imatinib-resistant chronic myeloid leukemia cells ⬇️

artículo científico publicado el 1 de noviembre de 2011

Metformin inhibits melanoma development through autophagy and apoptosis mechanisms.

artículo científico publicado en 2011

Metformin, independent of AMPK, induces mTOR inhibition and cell-cycle arrest through REDD1.

artículo científico publicado en 2011

Modular synthesis of new C-aryl-nucleosides and their anti-CML activity

artículo científico publicado en 2018

Persistent activation of the Fyn/ERK kinase signaling axis mediates imatinib resistance in chronic myelogenous leukemia cells through upregulation of intracellular SPARC.

artículo científico publicado en 2010

Phenotypic and genotypic characterization of azacitidine-sensitive and resistant SKM1 myeloid cell lines

artículo científico publicado en 2014

Resveratrol promotes autophagic cell death in chronic myelogenous leukemia cells via JNK-mediated p62/SQSTM1 expression and AMPK activation

artículo científico publicado en 2010

SPARC represses E-cadherin and induces mesenchymal transition during melanoma development

artículo científico publicado en 2006

Simalikalactone E (SkE), a new weapon in the armamentarium of drugs targeting cancers that exhibit constitutive activation of the ERK pathway

artículo científico publicado en 2012

Sirtuin 7: a new marker of aggressiveness in prostate cancer

artículo científico publicado en 2017

Spleen tyrosine kinase functions as a tumor suppressor in melanoma cells by inducing senescence-like growth arrest

artículo científico publicado en 2009

Successful re-treatment of a relapsed V600E mutated HCL patient with low-dose vemurafenib.

artículo científico publicado en 2014

Synthesis and anti-cancer activities of new sulfonamides 4-substituted-triazolyl nucleosides

artículo científico publicado en 2017

Targeting autophagy to fight hematopoietic malignancies.

artículo científico publicado en 2010

The PRKAA1/AMPKα1 pathway triggers autophagy during CSF1-induced human monocyte differentiation and is a potential target in CMML

artículo científico publicado en 2015

The anti-apoptotic Bcl-B protein inhibits BECN1-dependent autophagic cell death.

artículo científico publicado en 2012

The caspase 6 derived N-terminal fragment of DJ-1 promotes apoptosis via increased ROS production ⬇️

artículo científico publicado el 4 de mayo de 2012

The oncogenic tyrosine kinase Lyn impairs the pro-apoptotic function of Bim.

artículo científico publicado en 2018

The p53/p21Cip1/ Waf1 pathway mediates the effects of SPARC on melanoma cell cycle progression.

artículo científico publicado en 2010

The small heat shock protein B8 (HSPB8) confers resistance to bortezomib by promoting autophagic removal of misfolded proteins in multiple myeloma cells.

artículo científico publicado en 2014

Tumor-Derived Fibronectin Is Involved in Melanoma Cell Invasion and Regulated by V600E B-Raf Signaling Pathway

artículo científico publicado en 2006

Ultrasound-assisted one-pot synthesis of anti-CML nucleosides featuring 1,2,3-triazole nucleobase under iron-copper catalysis.

artículo científico publicado en 2012

[Autophagy, a key player in leukemogenesis and a therapeutic target in hematopoietic malignancies]

artículo científico publicado en 2017

Lista de obras de Guillaume Robert

A New Hydroxylated Nonaprenylhydroquinone from the Mediterranean Marine Sponge Sarcotragus spinosulus ⬇️

A new posttranslational regulation of REDD1/DDIT4 through cleavage by caspase 3 modifies its cellular function

ATP-competitive Plk1 inhibitors induce caspase 3-mediated Plk1 cleavage and activation in hematopoietic cell lines.

Acadesine kills chronic myelogenous leukemia (CML) cells through PKC-dependent induction of autophagic cell death

All tyrosine kinase inhibitor-resistant chronic myelogenous cells are highly sensitive to Ponatinib ⬇️

An miRNA-DNMT1 Axis Is Involved in Azacitidine Resistance and Predicts Survival in Higher-Risk Myelodysplastic Syndrome and Low Blast Count Acute Myeloid Leukemia

Autophagy is required for CSF-1-induced macrophagic differentiation and acquisition of phagocytic functions.

Azacitidine resistance caused by LAMP2 deficiency: a therapeutic window for the use of autophagy inhibitors in MDS/AML patients?

Azacitidine-resistant SKM1 myeloid cells are defective for AZA-induced mitochondrial apoptosis and autophagy.

BCL-B (BCL2L10) is overexpressed in patients suffering from multiple myeloma (MM) and drives an MM-like disease in transgenic mice

BCL2L10 positive cells in bone marrow are an independent prognostic factor of azacitidine outcome in myelodysplastic syndrome and acute myeloid leukemia

Caspase 1/11 Deficiency or Pharmacological Inhibition Mitigates Psoriasis-Like Phenotype in Mice

Differentiation inducing factor 3 mediates its anti-leukemic effect through ROS-dependent DRP1-mediated mitochondrial fission and induction of caspase-independent cell death

Dual role of Sp3 transcription factor as an inducer of apoptosis and a marker of tumour aggressiveness

FeCl3-promoted and ultrasound-assisted synthesis of resveratrol O-derived glycoside analogs.

HGF induces fibronectin matrix synthesis in melanoma cells through MAP kinase-dependent signaling pathway and induction of Egr-1.

IL-34 and CSF-1 display an equivalent macrophage differentiation ability but a different polarization potential.

Imatinib triggers mesenchymal-like conversion of CML cells associated with increased aggressiveness.

Implication and Regulation of AMPK during Physiological and Pathological Myeloid Differentiation

In Vitro and in Vivo Evaluation of Fully Substituted (5-(3-Ethoxy-3-oxopropynyl)-4-(ethoxycarbonyl)-1,2,3-triazolyl-glycosides as Original Nucleoside Analogues to Circumvent Resistance in Myeloid Malignancies

LAMP2 expression dictates azacytidine response and prognosis in MDS/AML

Limbic versus cognitive target for deep brain stimulation in treatment-resistant depression: accumbens more promising than caudate.

Low-dose vemurafenib induces complete remission in a case of hairy-cell leukemia with a V600E mutation.

Mechanism of action of the multikinase inhibitor Foretinib.

Mechanisms of AXL overexpression and function in Imatinib-resistant chronic myeloid leukemia cells ⬇️

Metformin inhibits melanoma development through autophagy and apoptosis mechanisms.

Metformin, independent of AMPK, induces mTOR inhibition and cell-cycle arrest through REDD1.

Modular synthesis of new C-aryl-nucleosides and their anti-CML activity

Persistent activation of the Fyn/ERK kinase signaling axis mediates imatinib resistance in chronic myelogenous leukemia cells through upregulation of intracellular SPARC.

Phenotypic and genotypic characterization of azacitidine-sensitive and resistant SKM1 myeloid cell lines

Resveratrol promotes autophagic cell death in chronic myelogenous leukemia cells via JNK-mediated p62/SQSTM1 expression and AMPK activation

SPARC represses E-cadherin and induces mesenchymal transition during melanoma development

Simalikalactone E (SkE), a new weapon in the armamentarium of drugs targeting cancers that exhibit constitutive activation of the ERK pathway

Sirtuin 7: a new marker of aggressiveness in prostate cancer

Spleen tyrosine kinase functions as a tumor suppressor in melanoma cells by inducing senescence-like growth arrest

Successful re-treatment of a relapsed V600E mutated HCL patient with low-dose vemurafenib.

Synthesis and anti-cancer activities of new sulfonamides 4-substituted-triazolyl nucleosides

Targeting autophagy to fight hematopoietic malignancies.

The PRKAA1/AMPKα1 pathway triggers autophagy during CSF1-induced human monocyte differentiation and is a potential target in CMML

The anti-apoptotic Bcl-B protein inhibits BECN1-dependent autophagic cell death.

The caspase 6 derived N-terminal fragment of DJ-1 promotes apoptosis via increased ROS production ⬇️

The oncogenic tyrosine kinase Lyn impairs the pro-apoptotic function of Bim.

The p53/p21Cip1/ Waf1 pathway mediates the effects of SPARC on melanoma cell cycle progression.

The small heat shock protein B8 (HSPB8) confers resistance to bortezomib by promoting autophagic removal of misfolded proteins in multiple myeloma cells.

Tumor-Derived Fibronectin Is Involved in Melanoma Cell Invasion and Regulated by V600E B-Raf Signaling Pathway

Ultrasound-assisted one-pot synthesis of anti-CML nucleosides featuring 1,2,3-triazole nucleobase under iron-copper catalysis.

[Autophagy, a key player in leukemogenesis and a therapeutic target in hematopoietic malignancies]