Lista de obras - Pilar Blancafort - Dominio Público Uruguay

A MYC-ZNF148-ID1/3 regulatory axis modulating cancer stem cell traits in aggressive breast cancer

artículo científico publicado en 2022

Activating PTEN Tumor Suppressor Expression with the CRISPR/dCas9 System

scientific article published on 14 December 2018

Analysis of an artificial zinc finger epigenetic modulator: widespread binding but limited regulation

artículo científico publicado en 2014

Atomistic molecular dynamics simulations of bioactive engrailed 1 interference peptides (EN1-iPeps).

artículo científico publicado en 2018

Aurantoside C Targets and Induces Apoptosis in Triple Negative Breast Cancer Cells

artículo científico publicado en 2018

Bidirectional modulation of endogenous EpCAM expression to unravel its function in ovarian cancer ⬇️

artículo científico publicado el 12 de febrero de 2013

Breaking through an epigenetic wall: re-activation of Oct4 by KRAB-containing designer zinc finger transcription factors.

artículo científico publicado en 2013

Breastmilk is a novel source of stem cells with multilineage differentiation potential.

artículo científico publicado en 2012

Cisplatin induces differentiation of breast cancer cells

artículo científico publicado en 2013

Crambescidin 800, Isolated from the Marine Sponge Monanchora viridis, Induces Cell Cycle Arrest and Apoptosis in Triple-Negative Breast Cancer Cells

artículo científico publicado en 2018

Designing transcription factor architectures for drug discovery.

artículo científico publicado en 2004

Development of zinc finger domains for recognition of the 5'-CNN-3' family DNA sequences and their use in the construction of artificial transcription factors

artículo científico publicado en 2005

Epigenetic reprogramming of cancer cells via targeted DNA methylation.

artículo científico publicado en 2012

Epigenome engineering in cancer: fairytale or a realistic path to the clinic?

artículo científico publicado en 2015

Evaluation of a modular strategy for the construction of novel polydactyl zinc finger DNA-binding proteins

artículo científico publicado en 2003

Expression of the Pluripotency Transcription Factor OCT4 in the Normal and Aberrant Mammary Gland

artículo científico publicado en 2013

Frequent lack of repressive capacity of promoter DNA methylation identified through genome-wide epigenomic manipulation

article

Gene expression in breastmilk cells is associated with maternal and infant characteristics.

artículo científico publicado en 2015

Generation of tumor-initiating cells by exogenous delivery of OCT4 transcription factor.

artículo científico publicado en 2011

Genetic reprogramming of tumor cells by zinc finger transcription factors

artículo científico publicado en 2005

Hallmarks of cancer: The CRISPR generation

artículo científico publicado en 2018

Honeybee venom and melittin suppress growth factor receptor activation in HER2-enriched and triple-negative breast cancer

scientific article published on 01 September 2020

In vivo selection of combinatorial libraries and designed affinity maturation of polydactyl zinc finger transcription factors for ICAM-1 provides new insights into gene regulation

artículo científico publicado en 2004

Long live the stem cell: the use of stem cells isolated from post mortem tissues for translational strategies

artículo científico publicado en 2014

Modulation of drug resistance by artificial transcription factors.

artículo científico publicado en 2008

Non-viral Methodology for Efficient Co-transfection

artículo científico publicado en 2018

Novel role of Engrailed 1 as a prosurvival transcription factor in basal-like breast cancer and engineering of interference peptides block its oncogenic function.

artículo científico publicado en 2013

PolI-driven integrative expression vectors for yeast

artículo científico publicado en 1997

Precision medicine by designer interference peptides: applications in oncology and molecular therapeutics

scientific article published on 21 October 2019

Promoter-targeted phage display selections with preassembled synthetic zinc finger libraries for endogenous gene regulation.

artículo científico publicado en 2004

Re-activation of a dormant tumor suppressor gene maspin by designed transcription factors

scientific article published on 23 October 2006

Re-expression of Selected Epigenetically Silenced Candidate Tumor Suppressor Genes in Cervical Cancer by TET2-directed Demethylation

artículo científico publicado en 2015

Reactivation of MASPIN in non-small cell lung carcinoma (NSCLC) cells by artificial transcription factors (ATFs)

artículo científico publicado en 2011

Remodeling genomes with artificial transcription factors (ATFs).

artículo científico publicado en 2010

Reprogramming epigenetic silencing: artificial transcription factors synergize with chromatin remodeling drugs to reactivate the tumor suppressor mammary serine protease inhibitor.

artículo científico publicado en 2008

Scanning the human genome with combinatorial transcription factor libraries.

artículo científico publicado en 2003

Sensitizing basal-like breast cancer to chemotherapy using nanoparticles conjugated with interference peptide.

artículo científico publicado en 2016

Sequence-specific biosensors report drug-induced changes in epigenetic silencing in living cells.

artículo científico publicado en 2012

Stable oncogenic silencing in vivo by programmable and targeted de novo DNA methylation in breast cancer

artículo científico publicado en 2015

Suppression of breast tumor growth and metastasis by an engineered transcription factor

artículo científico publicado en 2011

Synthetically controlling dendrimer flexibility improves delivery of large plasmid DNA.

scientific article published on 27 January 2017

Systemic delivery of modified mRNA encoding herpes simplex virus 1 thymidine kinase for targeted cancer gene therapy

artículo científico publicado en 2012

Targeted silencing of the oncogenic transcription factor SOX2 in breast cancer

artículo científico publicado en 2012

Targeting serous epithelial ovarian cancer with designer zinc finger transcription factors

artículo científico publicado en 2012

The CRISPR road: from bench to bedside on an RNA-guided path.

artículo científico publicado en 2015

The oncogene AAMDC links PI3K-AKT-mTOR signaling with metabolic reprograming in estrogen receptor-positive breast cancer

artículo científico publicado en 2021

The recognition of a noncanonical RNA base pair by a zinc finger protein.

artículo científico publicado en 1999

Triple-hit therapeutic approach for triple negative breast cancers using docetaxel nanoparticles, EN1-iPeps and RGD peptides

scientific article published on 02 May 2019

Tumor penetrating peptides inhibiting MYC as a potent targeted therapeutic strategy for triple-negative breast cancers

scientific article published on 03 August 2018

Tumour suppression by targeted intravenous non-viral CRISPRa using dendritic polymers

scientific article published on 27 June 2019

Waking up dormant tumor suppressor genes with zinc fingers, TALEs and the CRISPR/dCas9 system

artículo científico publicado en 2016

Writing and rewriting the epigenetic code of cancer cells: from engineered proteins to small molecules

artículo científico publicado en 2012

Zinc Fingers, TALEs, and CRISPR Systems: A Comparison of Tools for Epigenome Editing

artículo científico publicado en 2018

Lista de obras de Pilar Blancafort

A MYC-ZNF148-ID1/3 regulatory axis modulating cancer stem cell traits in aggressive breast cancer

Activating PTEN Tumor Suppressor Expression with the CRISPR/dCas9 System

Analysis of an artificial zinc finger epigenetic modulator: widespread binding but limited regulation

Atomistic molecular dynamics simulations of bioactive engrailed 1 interference peptides (EN1-iPeps).

Aurantoside C Targets and Induces Apoptosis in Triple Negative Breast Cancer Cells

Bidirectional modulation of endogenous EpCAM expression to unravel its function in ovarian cancer ⬇️

Breaking through an epigenetic wall: re-activation of Oct4 by KRAB-containing designer zinc finger transcription factors.

Breastmilk is a novel source of stem cells with multilineage differentiation potential.

Cisplatin induces differentiation of breast cancer cells

Crambescidin 800, Isolated from the Marine Sponge Monanchora viridis, Induces Cell Cycle Arrest and Apoptosis in Triple-Negative Breast Cancer Cells

Designing transcription factor architectures for drug discovery.

Development of zinc finger domains for recognition of the 5'-CNN-3' family DNA sequences and their use in the construction of artificial transcription factors

Epigenetic reprogramming of cancer cells via targeted DNA methylation.

Epigenome engineering in cancer: fairytale or a realistic path to the clinic?

Evaluation of a modular strategy for the construction of novel polydactyl zinc finger DNA-binding proteins

Expression of the Pluripotency Transcription Factor OCT4 in the Normal and Aberrant Mammary Gland

Frequent lack of repressive capacity of promoter DNA methylation identified through genome-wide epigenomic manipulation

Gene expression in breastmilk cells is associated with maternal and infant characteristics.

Generation of tumor-initiating cells by exogenous delivery of OCT4 transcription factor.

Genetic reprogramming of tumor cells by zinc finger transcription factors

Hallmarks of cancer: The CRISPR generation

Honeybee venom and melittin suppress growth factor receptor activation in HER2-enriched and triple-negative breast cancer

In vivo selection of combinatorial libraries and designed affinity maturation of polydactyl zinc finger transcription factors for ICAM-1 provides new insights into gene regulation

Long live the stem cell: the use of stem cells isolated from post mortem tissues for translational strategies

Modulation of drug resistance by artificial transcription factors.

Non-viral Methodology for Efficient Co-transfection

Novel role of Engrailed 1 as a prosurvival transcription factor in basal-like breast cancer and engineering of interference peptides block its oncogenic function.

PolI-driven integrative expression vectors for yeast

Precision medicine by designer interference peptides: applications in oncology and molecular therapeutics

Promoter-targeted phage display selections with preassembled synthetic zinc finger libraries for endogenous gene regulation.

Re-activation of a dormant tumor suppressor gene maspin by designed transcription factors

Re-expression of Selected Epigenetically Silenced Candidate Tumor Suppressor Genes in Cervical Cancer by TET2-directed Demethylation

Reactivation of MASPIN in non-small cell lung carcinoma (NSCLC) cells by artificial transcription factors (ATFs)

Remodeling genomes with artificial transcription factors (ATFs).

Reprogramming epigenetic silencing: artificial transcription factors synergize with chromatin remodeling drugs to reactivate the tumor suppressor mammary serine protease inhibitor.

Scanning the human genome with combinatorial transcription factor libraries.

Sensitizing basal-like breast cancer to chemotherapy using nanoparticles conjugated with interference peptide.

Sequence-specific biosensors report drug-induced changes in epigenetic silencing in living cells.

Stable oncogenic silencing in vivo by programmable and targeted de novo DNA methylation in breast cancer

Suppression of breast tumor growth and metastasis by an engineered transcription factor

Synthetically controlling dendrimer flexibility improves delivery of large plasmid DNA.

Systemic delivery of modified mRNA encoding herpes simplex virus 1 thymidine kinase for targeted cancer gene therapy

Targeted silencing of the oncogenic transcription factor SOX2 in breast cancer

Targeting serous epithelial ovarian cancer with designer zinc finger transcription factors

The CRISPR road: from bench to bedside on an RNA-guided path.

The oncogene AAMDC links PI3K-AKT-mTOR signaling with metabolic reprograming in estrogen receptor-positive breast cancer

The recognition of a noncanonical RNA base pair by a zinc finger protein.

Triple-hit therapeutic approach for triple negative breast cancers using docetaxel nanoparticles, EN1-iPeps and RGD peptides

Tumor penetrating peptides inhibiting MYC as a potent targeted therapeutic strategy for triple-negative breast cancers

Tumour suppression by targeted intravenous non-viral CRISPRa using dendritic polymers

Waking up dormant tumor suppressor genes with zinc fingers, TALEs and the CRISPR/dCas9 system

Writing and rewriting the epigenetic code of cancer cells: from engineered proteins to small molecules

Zinc Fingers, TALEs, and CRISPR Systems: A Comparison of Tools for Epigenome Editing