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A prohormone convertase cleavage site within a predicted alpha-helix mediates sorting of the neuronal and endocrine polypeptide VGF into the regulated secretory pathway

scientific journal article

Analysis of knockout mice suggests a role for VGF in the control of fat storage and energy expenditure

artículo científico publicado en 2009

Biochemical properties of the nerve growth factor-inducible large external (NILE) glycoprotein.

artículo científico publicado en 1983

Characterization of Gonadotrope Secretoproteome Identifies Neurosecretory Protein VGF-derived Peptide Suppression of Follicle-stimulating Hormone Gene Expression

artículo científico publicado en 2016

Comparison of VGF and trk mRNA distributions in the developing and adult rat nervous systems.

artículo científico publicado en 1997

Complex carbohydrates of cultured PC12 pheochromocytoma cells. Effects of nerve growth factor and comparison with neonatal and mature rat brain

artículo científico publicado en 1983

DNA sequences required for expression of the LH beta promoter in primary cultures of rat pituitary cells.

artículo científico publicado en 1990

Developmental expression of VGF mRNA in the prenatal and postnatal rat

artículo científico publicado el 27 de abril de 1998

ERMs colocalize transiently with L1 during neocortical axon outgrowth

scientific journal article

Effects of ethanol on axon outgrowth and branching in developing rat cortical neurons

scientific journal article

Embryonic ablation of neuronal VGF increases energy expenditure and reduces body weight.

artículo científico publicado en 2016

Expression of VGF mRNA in developing neuroendocrine and endocrine tissues.

artículo científico publicado en 2003

Expression of VGF mRNA in the adult rat central nervous system

artículo científico publicado el 27 de abril de 1998

Expression of luteinising hormone-beta subunit chloramphenicol acetyltransferase (LH-beta-CAT) fusion gene in rat pituitary cells: induction by cyclic 3'-adenosine monophosphate (cAMP).

artículo científico publicado en 1991

Functional binding interaction identified between the axonal CAM L1 and members of the ERM family

artículo científico publicado en 2002

Germline ablation of VGF increases lipolysis in white adipose tissue.

artículo científico publicado en 2012

Granins as disease-biomarkers: translational potential for psychiatric and neurological disorders.

artículo científico publicado en 2010

Grape-derived polyphenols produce antidepressant effects via VGF- and BDNF-dependent mechanisms

scientific article published on 10 May 2019

Interactions between the L1 cell adhesion molecule and ezrin support traction-force generation and can be regulated by tyrosine phosphorylation.

artículo científico publicado en 2008

L1 cell adhesion molecule promotes resistance to alcohol-induced silencing of growth cone responses to guidance cues

artículo científico publicado el 16 de febrero de 2011

Mining microarrays for metabolic meaning: nutritional regulation of hypothalamic gene expression

artículo científico publicado en 2004

Models and mechanisms of metabolic regulation: genes, stress, and the HPA and HPG axes.

artículo científico

Multiscale causal networks identify VGF as a key regulator of Alzheimer's disease

scientific article published on 07 August 2020

Nerve and epidermal growth factors induce the release of the Alzheimer amyloid precursor from PC 12 cell cultures.

artículo científico publicado en 1989

Nerve growth factor rapidly regulates VGF gene transcription through cycloheximide sensitive and insensitive pathways

artículo científico publicado en 1992

Nerve growth factor-inducible large external (NILE) glycoprotein: studies of a central and peripheral neuronal marker

artículo científico publicado en 1983

Nucleotide sequence and regulatory studies of VGF, a nervous system-specific mRNA that is rapidly and relatively selectively induced by nerve growth factor.

artículo científico publicado en 1991

Origins, actions and dynamic expression patterns of the neuropeptide VGF in rat peripheral and central sensory neurones following peripheral nerve injury

artículo científico publicado en 2008

Quantification of VGF- and pro-SAAS-derived peptides in endocrine tissues and the brain, and their regulation by diet and cold stress

scientific journal article

Regional differences in neurotrophin availability regulate selective expression of VGF in the developing limbic cortex.

artículo científico publicado en 2001

Release of chromaffin granule glycoproteins and proteoglycans from potassium-stimulated PC12 pheochromocytoma cells

artículo científico publicado en 1983

Release of the NILE and other glycoproteins from cultured PC12 rat pheochromocytoma cells and sympathetic neurons

artículo científico publicado en 1984

Role of Hypothalamic VGF in Energy Balance and Metabolic Adaption to Environmental Enrichment in Mice

artículo científico publicado en 2016

Role of VGF-derived carboxy-terminal peptides in energy balance and reproduction: analysis of "humanized" knockin mice expressing full-length or truncated VGF.

artículo científico publicado en 2015

Role of a VGF/BDNF/TrkB Autoregulatory Feedback Loop in Rapid-Acting Antidepressant Efficacy

artículo científico publicado en 2018

Role of neurotrophins in the development and function of neural circuits that regulate energy homeostasis

artículo científico publicado en 2012

Stimulation of pituitary luteinizing hormone secretion by gonadotropin-releasing hormone is not coupled to beta-luteinizing hormone gene transcription

artículo científico publicado en 1988

Stimulation of vgf gene expression by NGF is mediated through multiple signal transduction pathways involving protein phosphorylation

article

Structural features of the nerve growth factor inducible large external glycoprotein of PC12 pheochromocytoma cells and brain.

artículo científico publicado en 1983

The Extended Granin Family: Structure, Function, and Biomedical Implications

artículo científico publicado el 23 de agosto de 2011

The Prohormone VGF Regulates β Cell Function via Insulin Secretory Granule Biogenesis.

artículo científico publicado en 2017

The VGF-derived peptide TLQP-21 contributes to inflammatory and nerve injury-induced hypersensitivity

artículo científico publicado en 2014

The granin VGF promotes genesis of secretory vesicles, and regulates circulating catecholamine levels and blood pressure.

scientific article published on 04 February 2014

The messenger RNA encoding VGF, a neuronal peptide precursor, is rapidly regulated in the rat central nervous system by neuronal activity, seizure and lesion.

artículo científico publicado en 1998

The neurotrophin-inducible gene Vgf regulates hippocampal function and behavior through a brain-derived neurotrophic factor-dependent mechanism

artículo científico publicado en 2008

VGF ablation blocks the development of hyperinsulinemia and hyperglycemia in several mouse models of obesity

scientific journal article

VGF and Its C-Terminal Peptide TLQP-62 Regulate Memory Formation in Hippocampus via a BDNF-TrkB-Dependent Mechanism.

artículo científico publicado en 2015

VGF is required for obesity induced by diet, gold thioglucose treatment, and agouti and is differentially regulated in pro-opiomelanocortin- and neuropeptide Y-containing arcuate neurons in response to fasting

scientific journal article