Lista de obras -

A new family of membrane electron transporters and its substrates, including a new cell envelope peroxiredoxin, reveal a broadened reductive capacity of the oxidative bacterial cell envelope

artículo científico publicado en 2012

A simple and effective strategy for labeling cysteine sulfenic acid in proteins by utilization of β-ketoesters as cleavable probes.

artículo científico publicado en 2012

Acyl-lipid desaturases and Vipp1 cooperate in cyanobacteria to produce novel omega-3 PUFA-containing glycolipids

scientific article published on 06 May 2020

AhpF can be dissected into two functional units: tandem repeats of two thioredoxin-like folds in the N-terminus mediate electron transfer from the thioredoxin reductase-like C-terminus to AhpC.

artículo científico publicado en 2000

Amphibacillus xylanus NADH oxidase and Salmonella typhimurium alkyl-hydroperoxide reductase flavoprotein components show extremely high scavenging activity for both alkyl hydroperoxide and hydrogen peroxide in the presence of S. typhimurium alkyl-hy ⬇️

artículo científico publicado el 27 de octubre de 1995

An Atlas of Peroxiredoxins Created Using an Active Site Profile-Based Approach to Functionally Relevant Clustering of Proteins.

artículo científico publicado en 2017

An NADH-dependent bacterial thioredoxin reductase-like protein in conjunction with a glutaredoxin homologue form a unique peroxiredoxin (AhpC) reducing system in Clostridium pasteurianum.

artículo científico publicado en 2002

An iron-binding protein, Dpr, from Streptococcus mutans prevents iron-dependent hydroxyl radical formation in vitro.

artículo científico publicado en 2002

An unusual surface peroxiredoxin protects invasive Entamoeba histolytica from oxidant attack.

artículo científico publicado en 2005

Analysis of the Kinetic Mechanism of Enterococcal NADH Peroxidase Reveals Catalytic Roles for NADH Complexes with both Oxidized and Two-Electron-Reduced Enzyme Forms ⬇️

artículo científico publicado el 31 de octubre de 1995

Analysis of the link between enzymatic activity and oligomeric state in AhpC, a bacterial peroxiredoxin

artículo científico publicado en 2005

Analysis of the peroxiredoxin family: using active-site structure and sequence information for global classification and residue analysis

artículo científico publicado en 2010

Attachment of the N-terminal domain of Salmonella typhimurium AhpF to Escherichia coli thioredoxin reductase confers AhpC reductase activity but does not affect thioredoxin reductase activity.

artículo científico publicado en 2000

Au-ACRAMTU-PEt3 Alters Redox Balance To Inhibit T Cell Proliferation and Function

artículo científico publicado en 2015

Backbone chemical shift assignments for Xanthomonas campestris peroxiredoxin Q in the reduced and oxidized states: a dramatic change in backbone dynamics.

artículo científico publicado en 2015

Bacterial defenses against oxidants: mechanistic features of cysteine-based peroxidases and their flavoprotein reductases

artículo científico publicado en 2005

Chemical approaches to detect and analyze protein sulfenic acids

artículo científico publicado en 2014

Conformational and oligomeric effects on the cysteine pK(a) of tryparedoxin peroxidase

artículo científico publicado en 2010

Conformational studies of the robust 2-Cys peroxiredoxin Salmonella typhimurium AhpC by solution phase hydrogen/deuterium (H/D) exchange monitored by electrospray ionization mass spectrometry ⬇️

artículo científico publicado el 30 de abril de 2011

Crystal structure of alkyl hydroperoxidase D like protein PA0269 from Pseudomonas aeruginosa: homology of the AhpD-like structural family.

artículo científico publicado en 2011

Cysteine p K a Values for the Bacterial Peroxiredoxin AhpC † ‡

artículo científico publicado en 2008

Cysteine-Based Redox Switches in Enzymes ⬇️

artículo científico publicado el 17 de septiembre de 2010

Cysteine-Mediated Redox Regulation of Cell Signaling in Chondrocytes Stimulated With Fibronectin Fragments.

artículo científico publicado en 2015

D-alanine modification of a protease-susceptible outer membrane component by the Bordetella pertussis dra locus promotes resistance to antimicrobial peptides and polymorphonuclear leukocyte-mediated killing

artículo científico publicado en 2013

Decreasing peroxiredoxin II expression decreases glutathione, alters cell cycle distribution, and sensitizes glioma cells to ionizing radiation and H(2)O(2).

artículo científico publicado en 2008

Differential Kinetics of Two-Cysteine Peroxiredoxin Disulfide Formation Reveal a Novel Model for Peroxide Sensing.

artículo científico publicado en 2018

Differential peroxiredoxin hyperoxidation regulates MAP kinase signaling in human articular chondrocytes

artículo científico publicado en 2019

Discovering mechanisms of signaling-mediated cysteine oxidation.

artículo científico publicado en 2008

Dissecting peroxiredoxin catalysis: separating binding, peroxidation, and resolution for a bacterial AhpC

artículo científico publicado en 2015

Distribution and Features of the Six Classes of Peroxiredoxins

artículo científico publicado en 2016

Electrostatics of cysteine residues in proteins: parameterization and validation of a simple model.

artículo científico publicado en 2012

Endogenous, regulatory cysteine sulfenylation of ERK kinases in response to proliferative signals.

artículo científico publicado en 2017

Endosomal H2O2 production leads to localized cysteine sulfenic acid formation on proteins during lysophosphatidic acid-mediated cell signaling

artículo científico publicado en 2014

Evaluating peroxiredoxin sensitivity toward inactivation by peroxide substrates.

artículo científico publicado en 2013

Experimentally Dissecting the Origins of Peroxiredoxin Catalysis

artículo científico publicado en 2017

Extracellular SOD-derived H2O2 promotes VEGF signaling in caveolae/lipid rafts and post-ischemic angiogenesis in mice

artículo científico publicado en 2010

Fluorescent and affinity-based tools to detect cysteine sulfenic acid formation in proteins

artículo científico publicado en 2007

Functional site profiling and electrostatic analysis of cysteines modifiable to cysteine sulfenic acid.

artículo científico publicado en 2008

H2O2 oxidation of cysteine residues in c-Jun N-terminal kinase 2 (JNK2) contributes to redox regulation in human articular chondrocytes

artículo científico publicado en 2018

Human mitochondrial branched chain aminotransferase: structural basis for substrate specificity and role of redox active cysteines

artículo científico publicado en 2003

Hydroxyapatite chromatography: altering the phosphate-dependent elution profile of protein as a function of pH

artículo científico publicado en 2003

Identification of a peroxide-sensitive redox switch at the CXXC motif in the human mitochondrial branched chain aminotransferase.

artículo científico publicado en 2002

Introduction to approaches and tools for the evaluation of protein cysteine oxidation

artículo científico publicado en 2020

Introduction: What we do and do not know regarding redox processes of thiols in signaling pathways

artículo científico publicado en 2015

Isoform-specific regulation of Akt by PDGF-induced reactive oxygen species ⬇️

artículo científico publicado el 13 de junio de 2011

Kinetic and thermodynamic features reveal that Escherichia coli BCP is an unusually versatile peroxiredoxin.

artículo científico publicado en 2011

Localized cysteine sulfenic acid formation by vascular endothelial growth factor: role in endothelial cell migration and angiogenesis ⬇️

artículo científico publicado el 25 de julio de 2011

Mapping the Active Site Helix-to-Strand Conversion of CxxxxC Peroxiredoxin Q Enzymes ⬇️

artículo científico publicado el 14 de septiembre de 2012

Measurement of Protein Sulfenic Acid Content ⬇️

artículo científico publicado el 1 de noviembre de 2008

Mitochondria-targeted Probes for Imaging Protein Sulfenylation.

artículo científico publicado en 2018

Mutant AhpC peroxiredoxins suppress thiol-disulfide redox deficiencies and acquire deglutathionylating activity

artículo científico publicado en 2008

NOX4 (NADPH Oxidase 4) and Poldip2 (Polymerase δ-Interacting Protein 2) Induce Filamentous Actin Oxidation and Promote Its Interaction With Vinculin During Integrin-Mediated Cell Adhesion

artículo científico publicado en 2018

Nitration transforms a sensitive peroxiredoxin 2 into a more active and robust peroxidase.

artículo científico publicado en 2014

Novel Application of 7-Chloro-4-nitrobenzo-2-oxa-1,3-diazole To Identify Cysteine Sulfenic Acid in the AhpC Component of Alkyl Hydroperoxide Reductase ⬇️

artículo científico publicado el 2 de diciembre de 1997

Novel hyperoxidation resistance motifs in 2-Cys peroxiredoxins

artículo científico publicado en 2018

Novel organic hydroperoxide-sensing and responding mechanisms for OhrR, a major bacterial sensor and regulator of organic hydroperoxide stress.

artículo científico publicado en 2006

Overview of peroxiredoxins in oxidant defense and redox regulation.

artículo científico publicado en 2011

Oxidative Stress Promotes Peroxiredoxin Hyperoxidation and Attenuates Pro-survival Signaling in Aging Chondrocytes.

artículo científico publicado en 2016

Oxidized and synchrotron cleaved structures of the disulfide redox center in the N-terminal domain of Salmonella typhimurium AhpF.

artículo científico publicado en 2005

PREX: PeroxiRedoxin classification indEX, a database of subfamily assignments across the diverse peroxiredoxin family

artículo científico publicado en 2011

Peroxiredoxin II Regulates Effector and Secondary Memory CD8+T Cell Responses ⬇️

artículo científico publicado el 10 de octubre de 2012

Peroxiredoxins as molecular triage agents, sacrificing themselves to enhance cell survival during a peroxide attack.

artículo científico publicado en 2012

Peroxiredoxins in Cancer and Response to Radiation Therapies

artículo científico publicado en 2019

Peroxiredoxins in parasites.

artículo científico publicado en 2012

Peroxiredoxins: guardians against oxidative stress and modulators of peroxide signaling

artículo científico publicado en 2015

Protein sulfenic acids in redox signaling.

artículo científico publicado en 2004

Reactive oxygen species mediate lysophosphatidic acid induced signaling in ovarian cancer cells.

artículo científico publicado en 2010

Redox proteins

artículo científico publicado en 2019

Redox regulation and trapping sulfenic acid in the peroxide-sensitive human mitochondrial branched chain aminotransferase.

artículo científico publicado en 2008

Redox-dependent dynamics of a dual thioredoxin fold protein: evolution of specialized folds.

scientific article published on June 2009

Relation of Pre-anthracycline Serum Bilirubin Levels to Left Ventricular Ejection Fraction After Chemotherapy.

artículo científico publicado en 2015

Requirement for the Two AhpF Cystine Disulfide Centers in Catalysis of Peroxide Reduction by Alkyl Hydroperoxide Reductase ⬇️

artículo científico publicado el 28 de octubre de 1997

Roles for the two cysteine residues of AhpC in catalysis of peroxide reduction by alkyl hydroperoxide reductase from Salmonella typhimurium.

artículo científico publicado en 1997

SVM-SulfoSite: A support vector machine based predictor for sulfenylation sites

artículo científico publicado en 2018

Simple synthesis of 1,3-cyclopentanedione derived probes for labeling sulfenic acid proteins ⬇️

artículo científico publicado el 8 de julio de 2011

Structural Changes Common to Catalysis in the Tpx Peroxiredoxin Subfamily

artículo científico publicado en 2009

Structural Evidence that Peroxiredoxin Catalytic Power Is Based on Transition-State Stabilization

artículo científico publicado en 2010

Structural and electrostatic asymmetry at the active site in typical and atypical peroxiredoxin dimers.

artículo científico publicado en 2012

Structural basis for the retroreduction of inactivated peroxiredoxins by human sulfiredoxin

artículo científico publicado en 2005

Structural changes upon peroxynitrite-mediated nitration of peroxiredoxin 2; nitrated Prx2 resembles its disulfide-oxidized form

artículo científico publicado en 2015

Structure, mechanism and regulation of peroxiredoxins

artículo científico publicado en 2003

Structure-based Insights into the Catalytic Power and Conformational Dexterity of Peroxiredoxins ⬇️

artículo científico publicado el 20 de abril de 2011

Substrate specificity and redox potential of AhpC, a bacterial peroxiredoxin

artículo científico publicado en 2007

Synthesis of chemical probes to map sulfenic acid modifications on proteins.

artículo científico publicado en 2005

The Oxidative State of Cysteine Thiol 144 Regulates the SIRT6 Glucose Homeostat.

artículo científico publicado en 2017

The SAMHD1 dNTP Triphosphohydrolase Is Controlled by a Redox Switch.

artículo científico publicado en 2017

The Sensitive Balance between the Fully Folded and Locally Unfolded Conformations of a Model Peroxiredoxin

artículo científico publicado en 2013

The basics of thiols and cysteines in redox biology and chemistry

artículo científico publicado en 2015

The requirement of reversible cysteine sulfenic acid formation for T cell activation and function.

artículo científico publicado en 2007

The reversible formation of cysteine sulfenic acid promotes B-cell activation and proliferation.

artículo científico publicado en 2012

Thiol-blocking electrophiles interfere with labeling and detection of protein sulfenic acids.

artículo científico publicado en 2013

Tuning of peroxiredoxin catalysis for various physiological roles

artículo científico publicado en 2014

Typical 2-Cys peroxiredoxins--structures, mechanisms and functions.

scientific article published on 24 March 2009

Vascular Bioactivation of Nitroglycerin by Aldehyde Dehydrogenase-2: REACTION INTERMEDIATES REVEALED BY CRYSTALLOGRAPHY AND MASS SPECTROMETRY

artículo científico publicado en 2012

Water-soluble triarylphosphines as biomarkers for protein S-nitrosation

artículo científico publicado en 2010

Lista de obras de

A new family of membrane electron transporters and its substrates, including a new cell envelope peroxiredoxin, reveal a broadened reductive capacity of the oxidative bacterial cell envelope

A simple and effective strategy for labeling cysteine sulfenic acid in proteins by utilization of β-ketoesters as cleavable probes.

Acyl-lipid desaturases and Vipp1 cooperate in cyanobacteria to produce novel omega-3 PUFA-containing glycolipids

AhpF can be dissected into two functional units: tandem repeats of two thioredoxin-like folds in the N-terminus mediate electron transfer from the thioredoxin reductase-like C-terminus to AhpC.

Amphibacillus xylanus NADH oxidase and Salmonella typhimurium alkyl-hydroperoxide reductase flavoprotein components show extremely high scavenging activity for both alkyl hydroperoxide and hydrogen peroxide in the presence of S. typhimurium alkyl-hy ⬇️

An Atlas of Peroxiredoxins Created Using an Active Site Profile-Based Approach to Functionally Relevant Clustering of Proteins.

An NADH-dependent bacterial thioredoxin reductase-like protein in conjunction with a glutaredoxin homologue form a unique peroxiredoxin (AhpC) reducing system in Clostridium pasteurianum.

An iron-binding protein, Dpr, from Streptococcus mutans prevents iron-dependent hydroxyl radical formation in vitro.

An unusual surface peroxiredoxin protects invasive Entamoeba histolytica from oxidant attack.

Analysis of the Kinetic Mechanism of Enterococcal NADH Peroxidase Reveals Catalytic Roles for NADH Complexes with both Oxidized and Two-Electron-Reduced Enzyme Forms ⬇️

Analysis of the link between enzymatic activity and oligomeric state in AhpC, a bacterial peroxiredoxin

Analysis of the peroxiredoxin family: using active-site structure and sequence information for global classification and residue analysis

Attachment of the N-terminal domain of Salmonella typhimurium AhpF to Escherichia coli thioredoxin reductase confers AhpC reductase activity but does not affect thioredoxin reductase activity.

Au-ACRAMTU-PEt3 Alters Redox Balance To Inhibit T Cell Proliferation and Function

Backbone chemical shift assignments for Xanthomonas campestris peroxiredoxin Q in the reduced and oxidized states: a dramatic change in backbone dynamics.

Bacterial defenses against oxidants: mechanistic features of cysteine-based peroxidases and their flavoprotein reductases

Chemical approaches to detect and analyze protein sulfenic acids

Conformational and oligomeric effects on the cysteine pK(a) of tryparedoxin peroxidase

Conformational studies of the robust 2-Cys peroxiredoxin Salmonella typhimurium AhpC by solution phase hydrogen/deuterium (H/D) exchange monitored by electrospray ionization mass spectrometry ⬇️

Crystal structure of alkyl hydroperoxidase D like protein PA0269 from Pseudomonas aeruginosa: homology of the AhpD-like structural family.

Cysteine p K a Values for the Bacterial Peroxiredoxin AhpC † ‡

Cysteine-Based Redox Switches in Enzymes ⬇️

Cysteine-Mediated Redox Regulation of Cell Signaling in Chondrocytes Stimulated With Fibronectin Fragments.

D-alanine modification of a protease-susceptible outer membrane component by the Bordetella pertussis dra locus promotes resistance to antimicrobial peptides and polymorphonuclear leukocyte-mediated killing

Decreasing peroxiredoxin II expression decreases glutathione, alters cell cycle distribution, and sensitizes glioma cells to ionizing radiation and H(2)O(2).

Differential Kinetics of Two-Cysteine Peroxiredoxin Disulfide Formation Reveal a Novel Model for Peroxide Sensing.

Differential peroxiredoxin hyperoxidation regulates MAP kinase signaling in human articular chondrocytes

Discovering mechanisms of signaling-mediated cysteine oxidation.

Dissecting peroxiredoxin catalysis: separating binding, peroxidation, and resolution for a bacterial AhpC

Distribution and Features of the Six Classes of Peroxiredoxins

Electrostatics of cysteine residues in proteins: parameterization and validation of a simple model.

Endogenous, regulatory cysteine sulfenylation of ERK kinases in response to proliferative signals.

Endosomal H2O2 production leads to localized cysteine sulfenic acid formation on proteins during lysophosphatidic acid-mediated cell signaling

Evaluating peroxiredoxin sensitivity toward inactivation by peroxide substrates.

Experimentally Dissecting the Origins of Peroxiredoxin Catalysis

Extracellular SOD-derived H2O2 promotes VEGF signaling in caveolae/lipid rafts and post-ischemic angiogenesis in mice

Fluorescent and affinity-based tools to detect cysteine sulfenic acid formation in proteins

Functional site profiling and electrostatic analysis of cysteines modifiable to cysteine sulfenic acid.

H2O2 oxidation of cysteine residues in c-Jun N-terminal kinase 2 (JNK2) contributes to redox regulation in human articular chondrocytes

Human mitochondrial branched chain aminotransferase: structural basis for substrate specificity and role of redox active cysteines

Hydroxyapatite chromatography: altering the phosphate-dependent elution profile of protein as a function of pH

Identification of a peroxide-sensitive redox switch at the CXXC motif in the human mitochondrial branched chain aminotransferase.

Introduction to approaches and tools for the evaluation of protein cysteine oxidation

Introduction: What we do and do not know regarding redox processes of thiols in signaling pathways

Isoform-specific regulation of Akt by PDGF-induced reactive oxygen species ⬇️

Kinetic and thermodynamic features reveal that Escherichia coli BCP is an unusually versatile peroxiredoxin.

Localized cysteine sulfenic acid formation by vascular endothelial growth factor: role in endothelial cell migration and angiogenesis ⬇️

Mapping the Active Site Helix-to-Strand Conversion of CxxxxC Peroxiredoxin Q Enzymes ⬇️

Measurement of Protein Sulfenic Acid Content ⬇️

Mitochondria-targeted Probes for Imaging Protein Sulfenylation.

Mutant AhpC peroxiredoxins suppress thiol-disulfide redox deficiencies and acquire deglutathionylating activity

NOX4 (NADPH Oxidase 4) and Poldip2 (Polymerase δ-Interacting Protein 2) Induce Filamentous Actin Oxidation and Promote Its Interaction With Vinculin During Integrin-Mediated Cell Adhesion

Nitration transforms a sensitive peroxiredoxin 2 into a more active and robust peroxidase.

Novel Application of 7-Chloro-4-nitrobenzo-2-oxa-1,3-diazole To Identify Cysteine Sulfenic Acid in the AhpC Component of Alkyl Hydroperoxide Reductase ⬇️

Novel hyperoxidation resistance motifs in 2-Cys peroxiredoxins

Novel organic hydroperoxide-sensing and responding mechanisms for OhrR, a major bacterial sensor and regulator of organic hydroperoxide stress.

Overview of peroxiredoxins in oxidant defense and redox regulation.

Oxidative Stress Promotes Peroxiredoxin Hyperoxidation and Attenuates Pro-survival Signaling in Aging Chondrocytes.

Oxidized and synchrotron cleaved structures of the disulfide redox center in the N-terminal domain of Salmonella typhimurium AhpF.

PREX: PeroxiRedoxin classification indEX, a database of subfamily assignments across the diverse peroxiredoxin family

Peroxiredoxin II Regulates Effector and Secondary Memory CD8+T Cell Responses ⬇️

Peroxiredoxins as molecular triage agents, sacrificing themselves to enhance cell survival during a peroxide attack.

Peroxiredoxins in Cancer and Response to Radiation Therapies

Peroxiredoxins in parasites.

Peroxiredoxins: guardians against oxidative stress and modulators of peroxide signaling

Protein sulfenic acids in redox signaling.

Reactive oxygen species mediate lysophosphatidic acid induced signaling in ovarian cancer cells.

Redox proteins

Redox regulation and trapping sulfenic acid in the peroxide-sensitive human mitochondrial branched chain aminotransferase.

Redox-dependent dynamics of a dual thioredoxin fold protein: evolution of specialized folds.

Relation of Pre-anthracycline Serum Bilirubin Levels to Left Ventricular Ejection Fraction After Chemotherapy.

Requirement for the Two AhpF Cystine Disulfide Centers in Catalysis of Peroxide Reduction by Alkyl Hydroperoxide Reductase ⬇️

Roles for the two cysteine residues of AhpC in catalysis of peroxide reduction by alkyl hydroperoxide reductase from Salmonella typhimurium.

SVM-SulfoSite: A support vector machine based predictor for sulfenylation sites

Simple synthesis of 1,3-cyclopentanedione derived probes for labeling sulfenic acid proteins ⬇️

Structural Changes Common to Catalysis in the Tpx Peroxiredoxin Subfamily

Structural Evidence that Peroxiredoxin Catalytic Power Is Based on Transition-State Stabilization

Structural and electrostatic asymmetry at the active site in typical and atypical peroxiredoxin dimers.

Structural basis for the retroreduction of inactivated peroxiredoxins by human sulfiredoxin