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6E11, a highly selective inhibitor of Receptor-Interacting Protein Kinase 1, protects cells against cold hypoxia-reoxygenation injury

artículo científico publicado en 2017

A role for lipid rafts in the protection afforded by docosahexaenoic acid against ethanol toxicity in primary rat hepatocytes.

artículo científico publicado en 2013

Acid sphingomyelinase deficiency protects from cisplatin-induced gastrointestinal damage.

artículo científico publicado en 2008

Apoptotic mitochondrial dysfunction induced by benzo(a)pyrene in liver epithelial cells: role of p53 and pHi changes.

artículo científico publicado en 2003

Chemotherapy enhances TNF-related apoptosis-inducing ligand DISC assembly in HT29 human colon cancer cells

Cinchonine, a potent efflux inhibitor to circumvent anthracycline resistance in vivo

artículo científico publicado el 15 de mayo de 1992

Cisplatin cytotoxicity: DNA and plasma membrane targets.

scientific article published on January 2008

Cisplatin-Induced Apoptosis Involves Membrane Fluidification via Inhibition of NHE1 in Human Colon Cancer Cells

scientific article published on 01 August 2007

Cisplatin-induced CD95 redistribution into membrane lipid rafts of HT29 human colon cancer cells.

artículo científico publicado en 2004

Cisplatin-induced apoptosis involves a Fas-ROCK-ezrin-dependent actin remodelling in human colon cancer cells.

artículo científico publicado en 2010

Colon-cancer cell variants producing regressive tumors in syngeneic rats, unlike variants yielding progressive tumors, attach to interstitial collagens through integrin alpha2beta1

scientific article published on 01 March 1996

Comparative effects of quinine and cinchonine in reversing multidrug resistance on human leukemic cell line K562/ADM.

artículo científico publicado en 1994

Confluence-dependent resistance in human colon cancer cells: role of reduced drug accumulation and low intrinsic chemosensitivity of resting cells

artículo científico publicado en 1992

Contribution of the cyclin-dependent kinase inhibitor p27KIP1 to the confluence-dependent resistance of HT29 human colon carcinoma cells

artículo científico publicado el 31 de agosto de 1998

Cooperative interaction of benzo[a]pyrene and ethanol on plasma membrane remodeling is responsible for enhanced oxidative stress and cell death in primary rat hepatocytes.

artículo científico publicado en 2014

Cytotoxicity of TRAIL/anticancer drug combinations in human normal cells

artículo científico publicado en 2006

Effects of interferon-gamma (IFN-gamma) and tumor necrosis factor-alpha (TNF-alpha) on the expression of LFA-1 in the moderate phenotype of leukocyte adhesion deficiency (LAD)

artículo científico publicado en 1989

Fas ligand-independent, FADD-mediated activation of the Fas death pathway by anticancer drugs.

artículo científico publicado en 1999

Heterogeneity in the molecular defect leading to the leukocyte adhesion deficiency

artículo científico publicado en 1988

Identification of Na+/H+ exchange as a new target for toxic polycyclic aromatic hydrocarbons.

artículo científico publicado en 2003

Identification of the couple GSK3α/c-Myc as a new regulator of hexokinase II in benzo[a]pyrene-induced apoptosis

scientific journal article

Localization of Fas/CD95 into the lipid rafts on down-modulation of the phosphatidylinositol 3-kinase signaling pathway

artículo científico publicado en 2008

Milk fermented by Propionibacterium freudenreichii induces apoptosis of HGT-1 human gastric cancer cells

artículo científico publicado en 2012

NHE-1 relocation outside cholesterol-rich membrane microdomains is associated with its benzo[a]pyrene-related apoptotic function.

artículo científico publicado en 2012

Nongenomic effects of cisplatin: acute inhibition of mechanosensitive transporters and channels without actin remodeling.

artículo científico publicado en 2010

P27KiP1 overexpression inhibits the growth and doxorubicin sensitivity of HT29 human colon cancer cells in vivo

artículo científico publicado en 2000

Physical and chemical modulation of lipid rafts by a dietary n-3 polyunsaturated fatty acid increases ethanol-induced oxidative stress

artículo científico publicado en 2011

Positive and negative regulation of apoptotic pathways by cytotoxic agents in hematological malignancies.

artículo científico publicado en 2000

Protective action of n-3 fatty acids on benzo[a]pyrene-induced apoptosis through the plasma membrane remodeling-dependent NHE1 pathway.

artículo científico publicado en 2013

RIPK1 protects from TNF-α-mediated liver damage during hepatitis

artículo científico publicado en 2016

RIPK1 protects hepatocytes from death in Fas-induced hepatitis

artículo científico publicado en 2017

Regulation of Na+/H+ exchanger 1 allosteric balance by its localization in cholesterol- and caveolin-rich membrane microdomains.

artículo científico publicado en 2008

Reversal of tumor resistance to apoptotic stimuli by alteration of membrane fluidity: therapeutic implications.

artículo científico publicado en 2007

Role of early plasma membrane events in chemotherapy-induced cell death.

artículo científico publicado en 2005

Role of intracellular glutathione in cell sensitivity to the apoptosis induced by tumor necrosis factor {alpha}-related apoptosis-inducing ligand/anticancer drug combinations.

artículo científico publicado en 2005

Sibiriline, a new small chemical inhibitor of receptor-interacting protein kinase 1, prevents immune-dependent hepatitis

artículo científico publicado en 2017

Soluble CD14 acts as a DAMP in human macrophages: origin and involvement in inflammatory cytokine/chemokine production

artículo científico publicado en 2017

Sphingolipids and response to chemotherapy.

artículo científico publicado en 2013

Targeting the ceramide system in cancer

artículo científico publicado el 23 de julio de 2011

The chemical inhibitors of cellular death, PJ34 and Necrostatin-1, down-regulate IL-33 expression in liver.

artículo científico publicado en 2015

The probiotic Propionibacterium freudenreichii as a new adjuvant for TRAIL-based therapy in colorectal cancer

artículo científico publicado en 2016

Unprecedented incorporation of α-emitter radioisotope 213Bi into porphyrin chelates with reference to a daughter isotope mediated assistance mechanism

artículo científico publicado en 2011

Upregulation of CASP genes in human tumor cells undergoing etoposide-induced apoptosis

artículo científico publicado el 4 de junio de 1998

[Experimental chemotherapy of peritoneal carcinomatosis of colonic origin in rats]

artículo científico publicado en 1992

[The Fas/Fas-ligand system: implications in the antitumor immune response and in the activity of cytotoxic agents]

artículo científico publicado en 1998